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Paclitaxel (Paclitaxel) - Hypertension - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypertension (94)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Paclitaxel where reactions include hypertension. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 94   Next >>

Possible Paclitaxel side effects in 71 year old female

Reported by a pharmacist from Brazil on 2012-08-20

Patient: 71 year old female, weighing 62.0 kg (136.4 pounds)

Reactions: Back Pain, Hyperaemia, Hypertension, Deep Vein Thrombosis

Drug(s) suspected as cause:
Paclitaxel

Other drugs received by patient: Dexamethasone; Ranitidine; Ondansetron; Diphenhydramine Hydrochloride



Possible Paclitaxel side effects in male

Reported by a physician from Japan on 2012-08-15

Patient: male, weighing 51.0 kg (112.2 pounds)

Reactions: Haemoptysis, Interstitial Lung Disease, Platelet Count Decreased, Hypertension

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Avastin
    Start date: 2010-11-16
    End date: 2010-11-16

Paclitaxel
    Start date: 2010-09-14
    End date: 2010-09-14

Avastin
    Start date: 2010-12-16
    End date: 2010-12-16

Paclitaxel
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Avastin
    Start date: 2010-10-14
    End date: 2010-10-14

Carboplatin
    Start date: 2010-09-14
    End date: 2010-09-14

Carboplatin
    Start date: 2010-12-16
    End date: 2010-12-16

Carboplatin
    Start date: 2010-11-16
    End date: 2010-11-16

Carboplatin
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Avastin
    Indication: Lung Adenocarcinoma Recurrent
    Start date: 2010-08-17
    End date: 2010-08-17

Paclitaxel
    Start date: 2010-10-14
    End date: 2010-10-14

Paclitaxel
    Start date: 2010-12-16
    End date: 2010-12-16

Carboplatin
    Start date: 2010-10-14
    End date: 2010-10-14

Avastin
    Start date: 2010-09-14
    End date: 2010-09-14

Paclitaxel
    Start date: 2010-11-16
    End date: 2010-11-16



Possible Paclitaxel side effects in 66 year old male

Reported by a pharmacist from United States on 2012-08-14

Patient: 66 year old male, weighing 60.7 kg (133.5 pounds)

Reactions: Anxiety, Blood Pressure Increased, Respiratory Depression, Hypertension, Infusion Related Reaction

Drug(s) suspected as cause:
Paclitaxel



Possible Paclitaxel side effects in 66 year old female

Reported by a physician from Germany on 2012-08-09

Patient: 66 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Oedema DUE To Cardiac Disease, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: date of most recent dose-11/jul/2012.
    Indication: non-Small Cell Lung Cancer Recurrent
    Start date: 2012-03-26

Avastin
    Dosage: date of most recent dose-11/jul/2012.
    Indication: non-Small Cell Lung Cancer Recurrent
    Start date: 2012-03-26

Carboplatin
    Dosage: date of most recent dose-11/jul/2012.
    Indication: non-Small Cell Lung Cancer Recurrent
    Start date: 2012-03-26

Placebo
    Indication: non-Small Cell Lung Cancer Recurrent

Other drugs received by patient: Bisoprolol Fumarate; Potassium Chloride; Dexamethasone; Oxazepam; Novalgin; Zofran; Zofran; Lasix; Tavor (Germany); Oxygen; Torsemide; Paroxetine; Dexamethasone; Dexamethasone; Ranitidine HCL; Ximovan; Kalium; Lasix; Ramipril; Optipect; Spironolactone; Torsemide; Ringer Solution; Levothyroxine Sodium; Torsemide; Pantoprazole; Clemastine Fumarate; Perenterol Forte; Kalium; Metoclopramide



Possible Paclitaxel side effects in 64 year old female

Reported by a physician from Italy on 2012-07-30

Patient: 64 year old female

Reactions: Extrasystoles, Heart Rate Increased, Vertigo, Scotoma, Hypertension, Erythema

Drug(s) suspected as cause:
Paclitaxel

Other drugs received by patient: Solu-Cortef; Doxorubicin HCL; Ranitidine HCL; Ondansetron; Trimeton / 00072502 /



Possible Paclitaxel side effects in male

Reported by a physician from Japan on 2012-07-27

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Pneumonia, Nasopharyngitis, Rash, Eczema, Colonic Polyp, Interstitial Lung Disease, Hypertension, Neutrophil Count Decreased

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Start date: 2012-02-01

Paclitaxel
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28
    End date: 2012-01-01

Avastin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28
    End date: 2011-12-28

Avastin
    Start date: 2012-03-15
    End date: 2012-03-15

Paclitaxel
    Start date: 2012-02-01
    End date: 2012-01-01

Carboplatin
    Start date: 2012-03-15
    End date: 2012-03-15

Ampicillin Sodium
    Indication: Interstitial Lung Disease
    Start date: 2012-05-02
    End date: 2012-05-09

Avastin
    Start date: 2012-02-01
    End date: 2012-02-01

Paclitaxel
    Start date: 2012-03-15
    End date: 2012-04-12

Carboplatin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28

Other drugs received by patient: Dexamethasone Sodium Phosphate; Rebamipide; Loxoprofen Sodium; Zofran; Restamin; Diclofenac Sodium; Sennoside; Brotizolam; Vitamedin (Japan); Gaster (Japan); Granisetron Hydrochloride



Possible Paclitaxel side effects in female

Reported by a physician from United States on 2012-07-23

Patient: female, weighing 93.0 kg (204.5 pounds)

Reactions: Tooth Loss, Tricuspid Valve Incompetence, Hot Flush, Mood Altered, Iron Deficiency Anaemia, Retinal Pigment Epitheliopathy, Back Pain, Osteopenia, Cervical Dysplasia, Joint Injury, Diverticulum, Metastases To Spine, Compression Fracture, Pancreatitis, Calculus Ureteric, Upper-Airway Cough Syndrome, Adnexa Uteri Cyst, Vitreous Floaters, Hydroureter, Depression, Injury, Decreased Appetite, Vomiting, Cataract, Retinal Melanoma, Lung Neoplasm, Musculoskeletal Pain, Thyroid Cyst, Pulmonary Valve Incompetence, Arthralgia, Oral Pain, Mitral Valve Incompetence, Asthenia, DRY Eye, Abdominal Hernia, Night Sweats, Weight Decreased, Femur Fracture, Metastases To Liver, Nocturia, Headache, Pericardial Effusion, Tendon Injury, Neoplasm Skin, Dyspepsia, Sexually Transmitted Disease, Sinus Congestion, Mastoid Disorder, Intervertebral Disc Protrusion, Hydronephrosis, Hiatus Hernia, Cardiac Murmur, Peptic Ulcer, Anaemia, General Physical Health Deterioration, Renal Cyst, Hypoaesthesia, Atelectasis, Pain, Bone Pain, Conjunctivitis, Nephrolithiasis, Fatigue, Neuropathy Peripheral, Biliary Dyskinesia, Photophobia, Pleural Effusion, Intervertebral Disc Degeneration, Sinusitis, RIB Fracture, Spondylolisthesis, Nausea, Myopia, Anxiety, Osteonecrosis of JAW, Diarrhoea, Oral Disorder, Osteosarcoma Metastatic, Bronchitis, Hypertension, Deep Vein Thrombosis

Drug(s) suspected as cause:
Paclitaxel

Zometa
    Dosage: 4 mg, unk
    Indication: Metastases To Bone
    Start date: 2002-03-04
    End date: 2004-09-01

Aredia
    Dosage: 90 mg, unk
    End date: 2001-02-21

Other drugs received by patient: Lipitor; Cefuroxime Axetil; Vitamin D; Hydrocodone Bitartrate and Acetaminophen; Motrin; Cytoxan; Folate Sodium; Oxycodone HCL; Amoxicillin; Trazodone Hydrochloride; Depo-Medrol; Arimidex; Radiation Therapy; Lupron; Paxil; Sertraline Hydrochloride; Zoloft; Robaxin; Magnesium Sulfate; Alpha Lipoic Acid; Aromasin; Avastin; Femara; Prochlorperazine; Aspirin; Multivitamin ^lappe^; Adriamycin PFS; Anzemet; Fish OIL; Turmeric; Simvastatin; Calcium; Zoladex; Taxotere; Hydrogen Peroxide Mouth Rinse; Methocarbamol; Prilosec; Penicillin VK; Dexamethasone; Clindamycin; Fexofenadine; Taxol; Ethyol; Magace; Pepcid; Lortab; Oophorectomy



Possible Paclitaxel side effects in female

Reported by a individual with unspecified qualification from United States on 2012-07-16

Patient: female, weighing 114.1 kg (251.0 pounds)

Reactions: Hypertension

Drug(s) suspected as cause:
Paclitaxel
    Dosage: 270 mg

Carboplatin
    Dosage: 688 mg

Other drugs received by patient: Potassium Chloride



Possible Paclitaxel side effects in female

Reported by a physician from Germany on 2012-07-12

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Hypercholesterolaemia, Cholestasis, Pancreatitis Chronic, Metastases To Lymph Nodes, Hypertension

Drug(s) suspected as cause:
Herceptin
    Dosage: 384 mg/lbs
    Indication: Breast Cancer
    Start date: 2012-01-04

Paclitaxel
    Dosage: 183 mg/lbs
    Indication: Metastases To Lymph Nodes
    Start date: 2012-01-11
    End date: 2012-03-28

Other drugs received by patient: Hydrochlorothiazide; Omeprazole; Ramipril; Dipyrone TAB



Possible Paclitaxel side effects in male

Reported by a physician from Japan on 2012-07-12

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Pneumonia, Nasopharyngitis, Rash, Eczema, Pruritus Generalised, Colonic Polyp, Interstitial Lung Disease, Insomnia, Bone Marrow Failure, Neutropenia, Neutrophil Count Decreased, Hypertension

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Start date: 2012-03-15
    End date: 2012-03-15

Carboplatin
    Start date: 2012-03-15
    End date: 2012-03-15

Paclitaxel
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-03-15
    End date: 2012-04-12

Sulbacilline
    Indication: Interstitial Lung Disease
    Start date: 2012-05-02
    End date: 2012-05-09

Avastin
    Start date: 2012-02-01
    End date: 2012-02-01

Carboplatin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-02-01
    End date: 2012-02-01

Avastin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28
    End date: 2011-12-28

Other drugs received by patient: Loxoprofen; Famotidine; Dexamethasone Sodium Phosphate; Restamin; Granisetron; Diclofenac Sodium; Sennoside; Vitamedin; Rebamipide; Zofran



Possible Paclitaxel side effects in male

Reported by a physician from Japan on 2012-07-06

Patient: male, weighing 57.0 kg (125.4 pounds)

Reactions: Nasopharyngitis, Pneumonia, Eczema, Rash, Colonic Polyp, Interstitial Lung Disease, Insomnia, Neutrophil Count Decreased, Hypertension

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Start date: 2012-02-01
    End date: 2012-02-01

Carboplatin
    Start date: 2012-03-15
    End date: 2012-03-15

Carboplatin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-02-01
    End date: 2012-02-01

Avastin
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2011-12-28
    End date: 2011-12-28

Avastin
    Start date: 2012-03-15
    End date: 2012-03-15

Paclitaxel
    Indication: Lung Adenocarcinoma Metastatic
    Start date: 2012-03-15
    End date: 2012-04-12

Sulbacilline
    Indication: Interstitial Lung Disease
    Start date: 2012-05-02
    End date: 2012-05-09

Other drugs received by patient: Granisetron; Dexamethasone Sodium Phosphate; Loxoprofen; Sennoside; Famotidine; Diclofenac Sodium; Vitamedin; Rebamipide; Restamin; Zofran



Possible Paclitaxel side effects in

Reported by a individual with unspecified qualification from Japan on 2012-07-06

Patient:

Reactions: White Blood Cell Count Decreased, Pruritus, Alanine Aminotransferase Increased, Hypoaesthesia, Rash, Haemoglobin Decreased, Arthralgia, Diarrhoea, Aspartate Aminotransferase Increased, Platelet Count Decreased, Acute Lung Injury, Neutrophil Count Decreased, Hypertension, Myocardial Infarction

Adverse event resulted in: death

Drug(s) suspected as cause:
Pemetrexed Disodium
    Indication: non-Small Cell Lung Cancer

Paclitaxel
    Indication: non-Small Cell Lung Cancer

Cisplatin
    Indication: non-Small Cell Lung Cancer

Carboplatin
    Indication: non-Small Cell Lung Cancer

Gemcitabine Hydrochloride
    Indication: non-Small Cell Lung Cancer

Avastin
    Indication: non-Small Cell Lung Cancer



Possible Paclitaxel side effects in female

Reported by a physician from Germany on 2012-07-05

Patient: female, weighing 64.0 kg (140.8 pounds)

Reactions: Hypercholesterolaemia, Cholestasis, Pancreatitis Chronic, Metastases To Lymph Nodes, Hypertension

Drug(s) suspected as cause:
Herceptin
    Dosage: 384 mg/lbs
    Indication: Breast Cancer
    Start date: 2012-01-04

Paclitaxel
    Dosage: 183 mg/lbs
    Indication: Metastases To Lymph Nodes
    Start date: 2012-01-11
    End date: 2012-03-28

Other drugs received by patient: Omeprazole; Hydrochlorothiazide; Dipyrone TAB; Ramipril



Possible Paclitaxel side effects in

Reported by a individual with unspecified qualification from France on 2012-06-26

Patient:

Reactions: Pulmonary Haemorrhage, Neuropathy Peripheral, Intestinal Perforation, Neutropenia, Onycholysis, Hypertension, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Paclitaxel
    Dosage: on days 1, 8, 15
    Indication: non-Small Cell Lung Cancer Metastatic

Avastin
    Dosage: on day 1
    Indication: non-Small Cell Lung Cancer Metastatic



Possible Paclitaxel side effects in 33 year old female

Reported by a physician from Spain on 2012-06-25

Patient: 33 year old female, weighing 60.0 kg (132.0 pounds)

Reactions: Cardio-Respiratory Arrest, Renal Failure, Venous Thrombosis, Encephalopathy, Hypertension

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-16
    End date: 2012-03-01

Paclitaxel
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-16
    End date: 2012-03-15

Zoledronic Acid
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-16
    End date: 2012-03-15

Other drugs received by patient: Naproxen; Acetaminophen; Codeine Sulfate; Capoten



Possible Paclitaxel side effects in female

Reported by a individual with unspecified qualification from United States on 2012-06-25

Patient: female, weighing 68.5 kg (150.7 pounds)

Reactions: Abdominal Pain, Vomiting, Gallbladder Obstruction, Diarrhoea, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: cycle: 1; over 3 hours on day 1; tota dose administered: 243 mg; last dose prior to sae:15 sep 2011
    Indication: Fallopian Tube Cancer
    Start date: 2011-08-23

Cisplatin
    Dosage: cycle 1; on day 2; total dose administered: 135 mg; last dose prior to sae; 16 sep 2011
    Indication: Fallopian Tube Cancer
    Start date: 2011-08-23

Avastin
    Dosage: cycle 1; over 30-90 min on day 1; total dose administered: 1064 mg; last dose prior to sae: 26/jan/2
    Indication: Fallopian Tube Cancer
    Start date: 2011-08-23



Possible Paclitaxel side effects in 33 year old female

Reported by a physician from Spain on 2012-06-14

Patient: 33 year old female, weighing 60.0 kg (132.0 pounds)

Reactions: Cardio-Respiratory Arrest, Renal Failure, Venous Thrombosis, Encephalopathy, Hypertension

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-16
    End date: 2012-03-01

Paclitaxel
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-16
    End date: 2012-03-15

Zoledronic Acid
    Indication: Breast Cancer Metastatic
    Start date: 2012-02-16
    End date: 2012-03-15

Other drugs received by patient: Capoten; Codeine SUL TAB; Acetaminophen; Naproxen



Possible Paclitaxel side effects in

Reported by a health professional (non-physician/pharmacist) from Portugal on 2012-06-08

Patient:

Reactions: Haemoptysis, Anaemia, Renal Failure, Embolism, Thrombocytosis, Neutropenia, Hypertension, Thrombocytopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Avastin
    Indication: non-Small Cell Lung Cancer

Gemcitabine Hydrochloride
    Indication: non-Small Cell Lung Cancer

Pemetrexed Disodium
    Indication: non-Small Cell Lung Cancer

Paclitaxel
    Indication: non-Small Cell Lung Cancer



Possible Paclitaxel side effects in female

Reported by a individual with unspecified qualification from United States on 2012-06-08

Patient: female, weighing 61.8 kg (136.0 pounds)

Reactions: Anaemia, Posterior Reversible Encephalopathy Syndrome, Depressed Level of Consciousness, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: phase b (cycles 7-22): 15mg/kg iv over 30-90 min on day 1.date of last dose prior to sae: 11/apr/201
    Start date: 2012-04-11
    End date: 2012-05-02

Cisplatin
    Dosage: phase a (cycles 1-6): 75 mg/m2 ip on day 2.
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-11-30

Paclitaxel
    Dosage: phase a (cycles 1-6): 135mg/m2 iv over 3 hours on day 1.
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-11-30

Paclitaxel
    Dosage: phase a (cycles 1-6): 60 mg/m2 ip on day 8.
    Start date: 2011-11-30

Avastin
    Dosage: phase a (cycles 1-6): 15 mg/kg iv over 30-90 min on day 1, beginning with cycle 2.
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-11-30



Possible Paclitaxel side effects in

Reported by a individual with unspecified qualification from United States on 2012-06-07

Patient:

Reactions: Stomatitis, Renal Failure, Fatigue, Neuropathy Peripheral, Diarrhoea, Nausea, Hypertension

Drug(s) suspected as cause:
Avastin
    Indication: Pancreatic Carcinoma

Leucovorin Calcium
    Dosage: route: ivp
    Indication: Pancreatic Carcinoma

Fluorouracil
    Dosage: route: ambulatory pump
    Indication: Pancreatic Carcinoma

Paclitaxel
    Indication: Pancreatic Carcinoma

Oxaliplatin
    Indication: Pancreatic Carcinoma



Possible Paclitaxel side effects in female

Reported by a individual with unspecified qualification from United States on 2012-06-05

Patient: female

Reactions: Vomiting, Wound Dehiscence, Nausea, Pain, Hyperglycaemia, Proteinuria, Ejection Fraction Decreased, Neutropenia, Hypertension, Blood Creatinine Increased, Thrombocytopenia, Infection

Drug(s) suspected as cause:
Herceptin
    Dosage: for 23 weeks

Avastin
    Dosage: for 23 weeks
    Indication: Breast Cancer

Herceptin
    Dosage: loading dose
    Indication: Breast Cancer

Herceptin
    Dosage: total 54 weeks

Paclitaxel
    Dosage: days 1, 8 and 15
    Indication: Breast Cancer

Avastin
    Dosage: total 54 weeks

Carboplatin
    Dosage: auc=6 for 6 cycles
    Indication: Breast Cancer



Possible Paclitaxel side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-30

Patient: female, weighing 61.8 kg (136.0 pounds)

Reactions: Posterior Reversible Encephalopathy Syndrome, Anaemia, Depressed Level of Consciousness, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: phase a (cycles 1-6): 15 mg/kg iv over 30-90 min on day 1, beginning with cycle 2.
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-11-30

Paclitaxel
    Dosage: phase a (cycles 1-6): 60 mg/m2 ip on day 8.
    Start date: 2011-11-30

Cisplatin
    Dosage: phase a (cycles 1-6): 75 mg/m2 ip on day 2.
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-11-30

Avastin
    Dosage: phase b (cycles 7-22): 15mg/kg iv over 30-90 min on day 1.date of last dose prior to sae: 11/apr/201
    Start date: 2012-04-11
    End date: 2012-05-02

Paclitaxel
    Dosage: phase a (cycles 1-6): 135mg/m2 iv over 3 hours on day 1.
    Indication: Malignant Peritoneal Neoplasm
    Start date: 2011-11-30



Possible Paclitaxel side effects in female

Reported by a pharmacist from Brazil on 2012-05-29

Patient: female, weighing 78.6 kg (172.9 pounds)

Reactions: Abdominal Pain, Back Pain, DRY Mouth, Hyperaemia, Hypertension, Respiratory Distress

Drug(s) suspected as cause:
Paclitaxel

Other drugs received by patient: Cisplatin; Dexamethasone; Hydrocortisone; Cimetidine; Ondansetron; Cisplatin; Transamine CAP; Metoclopramide; Dexchlorpheniramin; Diphenhydramine HCL



Possible Paclitaxel side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-03

Patient: female

Reactions: Headache, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Pegfilgrastim
    Indication: Breast Cancer

Bevacizumab
    Indication: Breast Cancer

Cyclophosphamide
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer

Doxorubicin HCL
    Indication: Breast Cancer

Bevacizumab



Possible Paclitaxel side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-03

Patient: female

Reactions: Headache, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bevacizumab
    Indication: Breast Cancer

Bevacizumab

Doxorubicin HCL
    Indication: Breast Cancer

Cyclophosphamide
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer

Pegfilgrastim
    Indication: Breast Cancer



Possible Paclitaxel side effects in 50 year old female

Reported by a physician from United States on 2012-04-20

Patient: 50 year old female

Reactions: Electrocardiogram QT Prolonged, Haemoglobin Decreased, Oedema Peripheral, Chest Pain, Hypertension, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: maintenence dose.

Paclitaxel
    Indication: Breast Cancer

Herceptin
    Dosage: loading dose.
    Indication: Breast Cancer



Possible Paclitaxel side effects in 44 year old female

Reported by a physician from United States on 2012-04-13

Patient: 44 year old female, weighing 119.5 kg (262.9 pounds)

Reactions: White Blood Cell Count Decreased, Type 2 Diabetes Mellitus, Diabetes Mellitus, Lymphatic Disorder, Hyperglycaemia, Anaemia, Pancytopenia, Febrile Neutropenia, Cardiac Disorder, Diarrhoea, Blood Disorder, Platelet Count Decreased, Hypertension, Gastrooesophageal Reflux Disease

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Pegfilgrastim
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Indication: Breast Cancer
    Start date: 2011-03-24

Doxil
    Indication: Breast Cancer
    Start date: 2011-03-24

Bevacizumab
    Indication: Breast Cancer
    Start date: 2011-03-24

Paclitaxel
    Indication: Breast Cancer
    Start date: 2011-03-24

Other drugs received by patient: Tylenol (Caplet); Prochlorperazine; Toprol-XL; Cefepime; Mucinex; Diflucan; Bacitracin; Ambien; Pepcid; Tessalon



Possible Paclitaxel side effects in 50 year old male

Reported by a pharmacist from United States on 2012-04-10

Patient: 50 year old male, weighing 75.1 kg (165.2 pounds)

Reactions: Tachycardia, Anaphylactic Reaction, Tachypnoea, Respiratory Depression, Hypertension

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Paclitaxel



Possible Paclitaxel side effects in 67 year old female

Reported by a physician from United States on 2012-04-04

Patient: 67 year old female, weighing 68.5 kg (150.7 pounds)

Reactions: Abdominal Pain, Vomiting, Gallbladder Obstruction, Diarrhoea, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: cycle: 1; over 3 hours on day 1; tota dose administered: 243 mg; last dose prior to sae:15 sep 2011
    Indication: Fallopian Tube Cancer
    Start date: 2011-08-23

Paclitaxel
    Dosage: on day 8.

Avastin
    Dosage: cycle 1; over 30-90 min on day 1; total dose administered: 1064 mg; last dose prior to sae: 26/jan/2
    Indication: Fallopian Tube Cancer
    Start date: 2011-08-23

Cisplatin
    Dosage: cycle 1; on day 2; total dose administered: 135 mg; last dose prior to sae; 16 sep 2011
    Indication: Fallopian Tube Cancer
    Start date: 2011-08-23



Possible Paclitaxel side effects in 66 year old female

Reported by a individual with unspecified qualification from United States on 2012-04-03

Patient: 66 year old female, weighing 74.1 kg (163.0 pounds)

Reactions: Pelvic Infection, Colonic Fistula, Embolism, Respiratory Failure, Anaemia, Opportunistic Infection, Female Genital Tract Fistula, Hypertension, Convulsion

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: over 3 hrs on day 1. cycle 3; phase a.
    Indication: Ovarian Epithelial Cancer

Avastin
    Dosage: last dose prior to sae: 18 august 2010. cycle 3; phase a.
    Indication: Ovarian Epithelial Cancer

Cisplatin
    Dosage: cycle 3; phase a.
    Indication: Ovarian Epithelial Cancer



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