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Index of reports
> Cases with Atrial Fibrillation ()
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Paclitaxel where reactions include atrial fibrillation. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Paclitaxel side effects in female
Reported by a physician from Italy on 2012-08-22
Patient: female, weighing 57.0 kg (125.4 pounds)
Reactions: Atrial Fibrillation
Drug(s) suspected as cause:
Paclitaxel
Dosage: date of last dose prior to sae:10/jul/2012
Indication: Breast Cancer
Start date: 2012-05-28
End date: 2012-07-10
Paclitaxel
Start date: 2012-07-31
Herceptin
Dosage: maintanence dose
Pertuzumab
Dosage: maintanance dose
Herceptin
Dosage: date of last dose prior to sae: 10/jul/2012, loading dose
Indication: Breast Cancer
Start date: 2012-05-28
Pertuzumab
Dosage: date of last dose prior to sae was 10/jul/2012, loading dose
Indication: Breast Cancer
Start date: 2012-05-28
Other drugs received by patient: Bisoprolol Fumarate; Epirubicin; Fluorouracil
Possible Paclitaxel side effects in female
Reported by a physician from Italy on 2012-07-24
Patient: female, weighing 57.0 kg (125.4 pounds)
Reactions: Atrial Fibrillation
Drug(s) suspected as cause:
Paclitaxel
Dosage: date of last dose prior to sae:10/jul/2012
Indication: Breast Cancer
Start date: 2012-05-28
Herceptin
Dosage: date of last dose prior to sae: 10/jul/2012, loading dose
Indication: Breast Cancer
Start date: 2012-05-28
Fluorouracil
Indication: Breast Cancer
Pertuzumab
Dosage: maintanance dose
Pertuzumab
Dosage: date of last dose prior to sae was 10/jul/2012, loading dose
Indication: Breast Cancer
Start date: 2012-05-28
Herceptin
Dosage: maintanence dose
Epirubicin Hydrochloride
Indication: Breast Cancer
Other drugs received by patient: Bisoprolol Fumarate
Possible Paclitaxel side effects in male
Reported by a physician from United States on 2012-07-04
Patient: male, weighing 71.7 kg (157.7 pounds)
Reactions: Cardio-Respiratory Arrest, Pneumonia, Dehydration, Atrial Fibrillation
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 327.3 mg, q21d
Indication: Squamous Cell Carcinoma
Start date: 2010-11-30
Placebo
Dosage: unk
Indication: Squamous Cell Carcinoma
Cisplatin
Dosage: 140.25 mg, q21d
Indication: Squamous Cell Carcinoma
Start date: 2010-11-30
Afinitor
Dosage: unk
Indication: Squamous Cell Carcinoma
Blinded NO Treatment Received
Dosage: unk
Indication: Squamous Cell Carcinoma
Rad001
Dosage: 5 mg, qd
Administration route: Oral
Indication: Squamous Cell Carcinoma
Start date: 2010-12-07
Comparator Cetuximab
Dosage: 467.5 mg, unk
Indication: Squamous Cell Carcinoma
Start date: 2010-12-07
Other drugs received by patient: Nicotine; Xalatan; Symbicort; Tiotropium Bromide; Enzymes; Albuterol; Proventil; Enoxaparin; Dexamethasone Sodium Phosphate; Trusopt
Possible Paclitaxel side effects in male
Reported by a individual with unspecified qualification from United States on 2012-05-22
Patient: male, weighing 65.5 kg (144.0 pounds)
Reactions: Atrial Flutter, Oedema Peripheral, Atrial Fibrillation, Pulmonary Embolism
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 94 mg
End date: 2012-05-14
Cisplatin
Dosage: 47 mg
End date: 2012-05-14
Possible Paclitaxel side effects in female
Reported by a individual with unspecified qualification from United States on 2012-05-03
Patient: female
Reactions: Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Pegfilgrastim
Indication: Breast Cancer
Doxorubicin HCL
Indication: Breast Cancer
Bevacizumab
Cyclophosphamide
Indication: Breast Cancer
Paclitaxel
Indication: Breast Cancer
Bevacizumab
Indication: Breast Cancer
Possible Paclitaxel side effects in 76 year old female
Reported by a physician from United States on 2012-04-25
Patient: 76 year old female, weighing 61.6 kg (135.5 pounds)
Reactions: Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Blinded Megf0444a (Anti-Egfl7)
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Avastin
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Paclitaxel
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Carboplatin
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Possible Paclitaxel side effects in 76 year old female
Reported by a physician from United States on 2012-04-17
Patient: 76 year old female, weighing 61.6 kg (135.5 pounds)
Reactions: Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Avastin
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Paclitaxel
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Blinded Megf0444a (Anti-Egfl7)
Dosage: last doe prior to sae 12 mar 2012
Indication: non-Small Cell Lung Cancer
Start date: 2012-03-12
Possible Paclitaxel side effects in 58 year old female
Reported by a consumer/non-health professional from France on 2012-03-16
Patient: 58 year old female
Reactions: Tachyarrhythmia, Anaphylactic Shock, Bronchospasm, Atrial Fibrillation, Electrocardiogram QRS Complex Abnormal, Electrocardiogram ST Segment Elevation, Hypertension
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Paclitaxel
Dosage: 132 mg/ cyclic/ intravenous
Indication: Breast Cancer
Start date: 2012-01-26
End date: 2012-02-09
Ranitidine Hydrochloride
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Metoclopramide; Dexamethasone; Dexchlorpheniram Maleate; Ondansetron HCL; Letrozole
Possible Paclitaxel side effects in 58 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-16
Patient: 58 year old female
Reactions: Tachyarrhythmia, Anaphylactic Shock, Bronchospasm, Atrial Fibrillation
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Zantac
Dosage: 50 mg, unk
Paclitaxel
Dosage: 132 mg
Indication: Breast Cancer
Start date: 2012-01-26
End date: 2012-02-09
Other drugs received by patient: Ondansetron; Dexamethasone; Metoclopramide; Polaramine; Femara
Possible Paclitaxel side effects in female
Reported by a physician from Norway on 2012-02-23
Patient: female, weighing 103.0 kg (226.6 pounds)
Reactions: Left Ventricular Dysfunction, Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Avastin
Dosage: last dose prior to sae 19/dec/2011
Indication: Breast Cancer
Start date: 2011-08-02
End date: 2012-01-03
Epirubicin Hydrochloride
Dosage: last dose prior to sae 3/oct/2011
Indication: Breast Cancer
Start date: 2011-08-02
Paclitaxel
Dosage: last dose prior to sae 19/dec/2011
Indication: Breast Cancer
Start date: 2011-10-24
End date: 2012-01-03
Cyclophosphamide
Dosage: last dose prior to sae 3/oct/2011
Indication: Breast Cancer
Start date: 2011-08-02
Fluorouracil
Dosage: last dose prior to sae 3/oct/2011
Indication: Breast Cancer
Start date: 2011-08-02
Other drugs received by patient: Lovaza; Magnesium; Vitamin K TAB; Ascorbic Acid; Vitamin E; Vitamin D; Glucosamine; Nexium; Levothyroxine Sodium; Zinc Sulfate; Triobe; Liothyronin; Calcium
Possible Paclitaxel side effects in 56 year old male
Reported by a consumer/non-health professional from China on 2012-02-20
Patient: 56 year old male, weighing 96.0 kg (211.2 pounds)
Reactions: Atrial Fibrillation
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Blinded: Placebo
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-11
Paclitaxel
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-11
Blinded: Bevacizumab
Dosage: batch numbers:101388, 100614
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-11
Carboplatin
Indication: non-Small Cell Lung Cancer
Start date: 2011-11-11
Possible Paclitaxel side effects in male
Reported by a individual with unspecified qualification from United States on 2012-02-15
Patient: male, weighing 94.6 kg (208.1 pounds)
Reactions: Atrial Fibrillation, Acute Myocardial Infarction, Cardiac Failure Congestive
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 588 mg
End date: 2011-12-05
Carboplatin
Dosage: 1686 mg
End date: 2011-12-05
Possible Paclitaxel side effects in female
Reported by a physician from Spain on 2012-02-14
Patient: female, weighing 64.3 kg (141.5 pounds)
Reactions: Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: last dose prior to sae: 23 aug 2010
Indication: Ovarian Cancer
Avastin
Dosage: last dose prior to sae: 13 sep 2010. form: infusion
Indication: Ovarian Cancer
Paclitaxel
Dosage: last dose prior to sae: 23 aug 2010
Indication: Ovarian Cancer
Other drugs received by patient: Calcium Carbonate; Lorazepam; Omeprazole
Possible Paclitaxel side effects in 71 year old female
Reported by a individual with unspecified qualification from United States on 2012-01-30
Patient: 71 year old female, weighing 64.4 kg (141.7 pounds)
Reactions: Ejection Fraction Decreased, Atrial Fibrillation, Ventricular Fibrillation, Sinus Tachycardia, Hypokalaemia
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: over 1 hour on day 1,8 and 15
Indication: Ovarian Epithelial Cancer
Avastin
Dosage: over 30 -90 minutes on day 1 of cycle 2 plus
Indication: Ovarian Epithelial Cancer
Start date: 2011-11-03
Carboplatin
Dosage: auc 6 on day 1 (cycles 1-6),
Indication: Ovarian Epithelial Cancer
Start date: 2011-11-03
Paclitaxel
Dosage: dose reduced
Start date: 2011-11-23
Possible Paclitaxel side effects in 71 year old female
Reported by a individual with unspecified qualification from United States on 2011-12-30
Patient: 71 year old female, weighing 64.4 kg (141.7 pounds)
Reactions: Atrial Fibrillation, Ventricular Fibrillation, Sinus Tachycardia
Adverse event resulted in: death
Drug(s) suspected as cause:
Avastin
Dosage: over 30 -90 minutes on day 1 of cycle 2 plus
Indication: Ovarian Epithelial Cancer
Start date: 2011-11-03
Paclitaxel
Dosage: over 1 hour on day 1,8 and 15
Indication: Ovarian Epithelial Cancer
Paclitaxel
Dosage: dose reduced
Start date: 2011-11-23
Carboplatin
Dosage: auc 6 on day 1 (cycles 1-6),
Indication: Ovarian Epithelial Cancer
Start date: 2011-11-03
Possible Paclitaxel side effects in 84 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-04
Patient: 84 year old female, weighing 53.0 kg (116.6 pounds)
Reactions: Neoplasm Malignant, Febrile Neutropenia, Atrial Fibrillation, Bacterial Sepsis
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Paclitaxel
Dosage: 200mg/m2. inter date: 26jul11. duration : 1day.
Indication: non-Small Cell Lung Cancer
Start date: 2011-07-26
Carboplatin
Dosage: 6df
Indication: non-Small Cell Lung Cancer
Start date: 2011-07-06
Other drugs received by patient: Gemfibrozil; Coumadin; Carvedilol; Furosemide; Nitroglycerin; Albuterol; Fosamax; Amlodipine; Amiodarone HCL; Aspirin; Prednisone
Possible Paclitaxel side effects in male
Reported by a individual with unspecified qualification from Netherlands on 2011-10-26
Patient: male, weighing 90.0 kg (198.0 pounds)
Reactions: Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Indication: non-Small Cell Lung Cancer
Start date: 2011-10-18
Avastin
Indication: non-Small Cell Lung Cancer
Start date: 2011-10-18
Paclitaxel
Indication: non-Small Cell Lung Cancer
Start date: 2011-10-18
Possible Paclitaxel side effects in male
Reported by a individual with unspecified qualification from Netherlands on 2011-10-20
Patient: male, weighing 90.0 kg (198.0 pounds)
Reactions: Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Indication: non-Small Cell Lung Cancer
Start date: 2011-10-15
End date: 2011-10-15
Carboplatin
Indication: non-Small Cell Lung Cancer
Start date: 2011-10-15
End date: 2011-10-15
Avastin
Indication: non-Small Cell Lung Cancer
Start date: 2011-10-15
End date: 2011-10-15
Possible Paclitaxel side effects in male
Reported by a health professional (non-physician/pharmacist) from Netherlands on 2011-10-07
Patient: male, weighing 50.0 kg (110.0 pounds)
Reactions: Cachexia, Pneumonia, Circulatory Collapse, Atrial Fibrillation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Paclitaxel
Start date: 2006-03-17
Carboplatin
Indication: non-Small Cell Lung Cancer
Start date: 2006-03-17
Vinorelbine
Indication: non-Small Cell Lung Cancer
Start date: 2006-05-04
Other drugs received by patient: Radiotherapy
Possible Paclitaxel side effects in 71 year old male
Reported by a health professional (non-physician/pharmacist) from Germany on 2011-10-03
Patient: 71 year old male, weighing 50.0 kg (110.0 pounds)
Reactions: Pneumonia, Atrial Fibrillation, Circulatory Collapse
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: recent dose:23may06; 04-23may-2006
Indication: non-Small Cell Lung Cancer
Start date: 2006-03-17
Paclitaxel
Dosage: recent dose: 30-apr-2006.
Indication: non-Small Cell Lung Cancer
Start date: 2006-03-17
Vinorelbine
Dosage: recent dose:23may06
Indication: non-Small Cell Lung Cancer
Start date: 2006-05-04
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