This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Oxycontin (Oxycodone) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (1088)
Death (202)
Life Threatening Events (31)
Disability (31)
Reports by Reaction Type
Drug Dependence (154),
Pain (142),
Drug Withdrawal Syndrome (101),
Vomiting (75),
Substance Abuse (68),
Nausea (65),
Drug Abuse (60),
Death (58),
Suicidal Ideation (56),
Depression (53),
Anxiety (52),
Drug Ineffective (51)
Below are a few examples of reports where side effects / adverse reactions may be related to Oxycontin (Oxycodone). For a complete list or a specific selection of reports, please use the links above.
Possible Oxycontin side effects in 79 year old female
Reported by a consumer/non-health professional from United States on 2012-08-27
Patient: 79 year old female
Reactions: Hallucination, Visual, Hallucination, Auditory, Drug Interaction, Toxicity To Various Agents, Somnolence, Crying
Drug(s) suspected as cause:
Lexapro
Indication: Depression
Start date: 2007-01-01
Lunesta
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Morphine
Indication: Pain
Start date: 2011-11-01
End date: 2012-02-01
Oxycontin
Indication: Pain
Oxycontin
Other drugs received by patient: Vicodin
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-27
Patient: female
Reactions: Pain, Headache, Somnolence, Cardiac Disorder
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alprazolam
Lexapro
Oxycontin
Dosage: 80 mg, unk
Roxicodone
Possible Oxycontin side effects in 35 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-24
Patient: 35 year old male
Reactions: Oedema Peripheral, Pain, Rash Vesicular, Erythema, Herpes Zoster
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lasix
Dosage: unk
Administration route: Oral
Start date: 2012-06-01
End date: 2012-06-02
Lidocaine
Dosage: unk
Administration route: Topical
Indication: Pain
Start date: 2012-05-24
Lyrica
Dosage: unk
Administration route: Oral
Indication: Pain
Start date: 2012-05-01
End date: 2012-01-01
Lyrica
Dosage: 75 mg, 2x/day
Administration route: Oral
End date: 2012-05-06
Nefopam
Dosage: unk
Administration route: Oral
Start date: 2012-01-01
Nefopam
Dosage: unk
Indication: Pain
Start date: 2012-05-22
Oxycodone Hydrochloride
Dosage: unk
Administration route: Oral
Indication: Pain
Start date: 2012-05-23
End date: 2012-06-03
Oxycontin
Dosage: unk
Administration route: Oral
Indication: Pain
Start date: 2012-05-23
Pantoprazole Sodium
Dosage: 40 mg, daily
Administration route: Oral
Start date: 2012-05-29
End date: 2012-06-03
Remicade
Dosage: 400 mg,1 in 8 wk
Indication: Spondylitis
Start date: 2009-03-01
End date: 2012-04-18
Possible Oxycontin side effects in male
Reported by a physician from Japan on 2012-08-24
Patient: male
Reactions: Stomatitis, Alanine Aminotransferase Increased, Rash, Xeroderma, Constipation, Interstitial Lung Disease, Neoplasm Malignant, Cholangitis, Aspartate Aminotransferase Increased
Adverse event resulted in: death
Drug(s) suspected as cause:
Erlotinib Hydrochloride
Dosage: 100 mg, uid/qd
Administration route: Oral
Start date: 2011-12-27
End date: 2012-01-10
Erlotinib Hydrochloride
Dosage: 100 mg, uid/qd
Administration route: Oral
Indication: Adenocarcinoma Pancreas
Start date: 2011-11-28
End date: 2011-12-21
Gemcitabine Hydrochloride
Dosage: 1000 mg/m2, uid/qd
Start date: 2012-02-13
End date: 2012-02-13
Gemcitabine Hydrochloride
Dosage: 1000 mg/m2, uid/qd
Start date: 2012-01-04
End date: 2012-01-04
Gemcitabine Hydrochloride
Dosage: 1000 mg/m2, weekly
Start date: 2011-12-19
End date: 2011-12-26
Gemcitabine Hydrochloride
Dosage: 1000 mg/m2, weekly 3 weeks administration and 1 week rest
Start date: 2012-01-16
End date: 2012-01-30
Gemcitabine Hydrochloride
Dosage: 1000 mg/m2, weekly 2 weeks administration and 1 week rest
Indication: Adenocarcinoma Pancreas
Start date: 2011-11-28
End date: 2011-12-05
Levofloxacin
Dosage: 500 mg, uid/qd
Administration route: Oral
Indication: Cholangitis
Start date: 2011-12-11
End date: 2011-12-15
Oxycontin
Dosage: 10 mg, tid
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Levofloxacin; Loxonin; Morphine; Magmitt; Berizym; Pursennid; Lansoprazole
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: female
Reactions: Foot Operation, Poor Peripheral Circulation, Neck Surgery
Drug(s) suspected as cause:
Oxycontin
Possible Oxycontin side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Oxycontin
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: female
Reactions: Fatigue, Insomnia, Mental Disorder, Depression
Drug(s) suspected as cause:
Abilify
Indication: Mental Disorder
Abilify
Dosage: unk
Indication: Depression
Start date: 2012-01-01
Oxycontin
Dosage: 320 mg, hs
Administration route: Oral
Oxycontin
Dosage: 160 mg, pm
Administration route: Oral
Oxycontin
Dosage: 320 mg, am
Administration route: Oral
Indication: Pain
Possible Oxycontin side effects in 33 year old male
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: 33 year old male
Reactions: Euphoric Mood, Overdose, Suicide Attempt, Injury, Polysubstance Dependence, Drug Withdrawal Syndrome, Substance Abuse
Drug(s) suspected as cause:
Heroin
Indication: Drug Abuse
Methamphetamine Hydrochloride
Indication: Drug Abuse
Oxycontin
Dosage: unk
Indication: Pain
Start date: 2008-08-01
Possible Oxycontin side effects in 63 year old female
Reported by a physician from Spain on 2012-08-24
Patient: 63 year old female
Reactions: Akathisia, Myoclonus, Feeling Jittery, Dyskinesia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Naloxolne HCL
Indication: Rheumatoid Arthritis
Naloxolne HCL
Dosage: 20 mg, q12h
Administration route: Oral
Indication: Osteoarthritis
Start date: 2012-05-10
End date: 2012-05-11
Oxycontin
Indication: Rheumatoid Arthritis
Oxycontin
Dosage: unk
Indication: Osteoarthritis
Other drugs received by patient: Prednisone TAB; Calcium Carbonate; Omeprazole; Duragesic-100; Abstral; Arava; Lormetazepam; Enalapril Maleate; Actonel; Metamizole
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: female
Reactions: Gallbladder Operation
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oxycontin
Possible Oxycontin side effects in 57 year old male
Reported by a consumer/non-health professional from United States on 2012-08-23
Patient: 57 year old male, weighing 106.6 kg (234.5 pounds)
Reactions: Wrong Technique in Drug Usage Process, Deafness, Erythema, Abdominal Discomfort, Neurotoxicity, Brain Injury, Balance Disorder, Oedema Peripheral, Sensory Integrative Dysfunction, Unevaluable Event, Back Pain, Pain in Extremity, Inadequate Analgesia, Judgement Impaired, Drug Withdrawal Syndrome, Costochondritis, Decreased Interest, Apathy, Irritability, Affective Disorder, Euphoric Mood, Sleep Disorder, Major Depression, Nervous System Disorder, Disturbance in Attention, Drug Ineffective, Chills, Pain, Intentional Drug Misuse, Anhedonia, Fatigue, Neuropathy Peripheral, Neck Pain, Dizziness, Injury, Allodynia, Loss of Libido, Musculoskeletal Pain, Logorrhoea, Dysarthria, Anxiety, Hyperaesthesia, Arthralgia, Loss of Employment, Drug Dependence, Bradyphrenia, Depressed Mood
Drug(s) suspected as cause:
Oxycontin
Dosage: 160 mg, bid
End date: 2012-04-01
Oxycontin
Dosage: 20 mg, see text
Oxycontin
Dosage: 40 mg, unk
Oxycontin
Dosage: 10 mg, see text
Indication: Pain in Extremity
Start date: 2002-01-01
Other drugs received by patient: Interferon / 05982601 /; Pegintron / 01543001 /; Neupogen; Clonazepam; Lortab; Lexapro; Flexeril; Fluticasone Propionate; Ribavirin
Possible Oxycontin side effects in 37 year old male
Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-23
Patient: 37 year old male
Reactions: Dependence, Suicidal Ideation
Drug(s) suspected as cause:
Morphine
Indication: Product Used FOR Unknown Indication
Oxycontin
Indication: Product Used FOR Unknown Indication
Valium
Indication: Product Used FOR Unknown Indication
Possible Oxycontin side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-22
Patient: male
Reactions: Concussion, Victim of Crime, Incorrect Dose Administered, Haematoma
Drug(s) suspected as cause:
Oxycontin
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-22
Patient: female
Reactions: Hospitalisation, Gastrointestinal Disorder Therapy, Diabetes Mellitus, Gastrointestinal Disorder, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oxycontin
Dosage: 40 mg, daily
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Oxycontin
Dosage: 20 mg, bid
Administration route: Oral
Start date: 2012-01-01
Possible Oxycontin side effects in male
Reported by a physician from United States on 2012-08-21
Patient: male, weighing 62.1 kg (136.7 pounds)
Reactions: Complications of Transplanted Liver, Pain
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oxycodone HCL
Dosage: 15 mg, q4h
Indication: Product Used FOR Unknown Indication
Oxycontin
Dosage: 40 mg, q8h
Administration route: Oral
Indication: Pain
Start date: 2010-01-01
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-21
Patient: female
Reactions: Nausea, Pain, Inadequate Analgesia, Headache, Somnolence, Abdominal Pain Upper, Cardiac Disorder, Unevaluable Event
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Alprazolam
Indication: Product Used FOR Unknown Indication
Cardiac Medication
Indication: Product Used FOR Unknown Indication
Lexapro
Indication: Product Used FOR Unknown Indication
Oxycontin
Dosage: 80 mg, unk
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Roxicodone
Indication: Product Used FOR Unknown Indication
Possible Oxycontin side effects in 57 year old female
Reported by a physician from United States on 2012-08-20
Patient: 57 year old female
Reactions: Chest Pain, Drug Hypersensitivity
Drug(s) suspected as cause:
Celexa
Dosage: unk
Ciprofloxacin HCL
Dosage: unk
Gabapentin
Dosage: unk
Hydrocodone Bitartrate + Acetaminophen
Dosage: unk
Iodine
Dosage: unk
Morphine Sulfate
Dosage: unk
Oxycontin
Dosage: unk
Povidone-Iodine (Formula 47)
Dosage: unk
Prozac
Dosage: unk
Secretin INJ
Dosage: unk
Seroquel
Dosage: unk
Titanium Dioxide
Dosage: unk
Zyprexa
Dosage: unk
Possible Oxycontin side effects in female
Reported by a pharmacist from Japan on 2012-08-20
Patient: female
Reactions: Neoplasm Malignant, Pain
Drug(s) suspected as cause:
Oxycontin
Indication: Cancer Pain
Start date: 2012-07-24
Tramadol HCL
Dosage: 1dfx4 per day
Administration route: Oral
Indication: Pain
Possible Oxycontin side effects in 25 year old male
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 25 year old male, weighing 79.8 kg (175.6 pounds)
Reactions: Abdominal Pain, Gastrointestinal Pain, Amylase Increased, Abdominal Pain Upper
Drug(s) suspected as cause:
Oxycontin
Dosage: 10mg, twice daily, po
Administration route: Oral
Indication: Joint Surgery
Start date: 2012-05-01
End date: 2012-08-15
Oxycontin
Dosage: 10mg, twice daily, po
Administration route: Oral
Indication: Pain
Start date: 2012-05-01
End date: 2012-08-15
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: female
Reactions: Lymphadenopathy, Vomiting, Drug Ineffective, Nausea, Haemoptysis, Musculoskeletal Pain, Headache, Constipation, Product Size Issue, Neoplasm Malignant, Unevaluable Event, Decreased Appetite
Adverse event resulted in: death
Drug(s) suspected as cause:
Oxycodone HCL
Dosage: 10-20 mg q3-4 h prn
Indication: Pain
Start date: 2012-01-31
Oxycontin
Dosage: 10 mg, q12h
Indication: Pain
Start date: 2012-01-31
Xalkori
Dosage: 250 mg, bid
Administration route: Oral
Indication: Lung Neoplasm Malignant
Start date: 2012-02-22
End date: 2012-02-29
Other drugs received by patient: MS Contin; Tylenol (Caplet); Senokot; Zofran; Roxanol; Robitussin / 00048001 /; Klonopin; Sudafed S.a.; Chloraseptic; Vitamin B6; Vitamin B12 / 00056201 /; Tussionex; Viactiv / 00751501 /; Ambien; Fosamax
Possible Oxycontin side effects in 35 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-08-17
Patient: 35 year old male
Reactions: Oedema Peripheral, Pain, Rash Vesicular, Erythema, Herpes Zoster
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Lasix
Dosage: unk
Administration route: Oral
Indication: Oedema Peripheral
Start date: 2012-06-01
End date: 2012-06-02
Lidocaine
Dosage: unk
Administration route: Topical
Indication: Pain
Start date: 2012-05-24
Lyrica
Dosage: unk
Administration route: Oral
Indication: Pain
Start date: 2012-05-01
End date: 2012-01-01
Lyrica
Dosage: 75 mg, 2x/day
Administration route: Oral
End date: 2012-05-06
Nefopam
Dosage: unk
Indication: Pain
Start date: 2012-05-22
Nefopam
Dosage: unk
Administration route: Oral
Start date: 2012-01-01
Oxycodone Hydrochloride
Dosage: unk
Administration route: Oral
Indication: Pain
Start date: 2012-05-23
End date: 2012-06-03
Oxycontin
Dosage: unk
Administration route: Oral
Indication: Pain
Start date: 2012-05-23
Pantoprazole Sodium
Dosage: 40 mg, 1x/day
Administration route: Oral
Start date: 2012-05-29
End date: 2012-06-03
Remicade
Dosage: 400 mg,1 in 8 wk
Indication: Spondylitis
Start date: 2009-03-01
End date: 2012-04-18
Possible Oxycontin side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: male, weighing 64.0 kg (140.7 pounds)
Reactions: Negative Thoughts, Urinary Incontinence, Pain, Mental Status Changes, Suicidal Ideation, Abnormal Loss of Weight, Subcutaneous Abscess, Osteochondrosis, Anaemia, Drug Withdrawal Syndrome, Eating Disorder, Dysgeusia, Incoherent, Anxiety, Activities of Daily Living Impaired, Insomnia, Hypothyroidism, Parosmia, Mobility Decreased, Post Laminectomy Syndrome
Drug(s) suspected as cause:
Oxycontin
Dosage: 80 mg, q12h
Administration route: Oral
Oxycontin
Dosage: 480 mg, q12h
Indication: Pain
Other drugs received by patient: Valium; Synthroid; Zoloft; Unisom / 00000402 /; Valium; Neurontin
Possible Oxycontin side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: male
Reactions: Pulmonary Haemorrhage, Scapula Fracture, Road Traffic Accident, Traumatic Lung Injury, Spinal Column Injury, RIB Fracture
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oxycontin
Possible Oxycontin side effects in 35 year old male
Reported by a consumer/non-health professional from Canada on 2012-08-16
Patient: 35 year old male
Reactions: Pain, General Physical Health Deterioration, Drug Withdrawal Syndrome, Hypoaesthesia, Pallor, Substance Abuse, Suicidal Ideation, Overweight, Euphoric Mood, Overdose, Cyanosis, Social Avoidant Behaviour, Depression, Drug Dependence
Drug(s) suspected as cause:
Alcohol
Indication: Product Used FOR Unknown Indication
Cocaine
Indication: Product Used FOR Unknown Indication
Marijuana
Indication: Product Used FOR Unknown Indication
Oxycontin
Dosage: 20 tablet, daily
Indication: Product Used FOR Unknown Indication
Oxycontin
Dosage: unk unk, daily
Indication: Product Used FOR Unknown Indication
Percocet
Indication: Product Used FOR Unknown Indication
Possible Oxycontin side effects in 65 year old male
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: 65 year old male
Reactions: Psychotic Disorder, Judgement Impaired, Somnambulism, Feeling Abnormal, Amnesia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ativan
Dosage: unk unk, see text
Indication: Product Used FOR Unknown Indication
Haldol
Dosage: 25 mg, see text
Indication: Product Used FOR Unknown Indication
Oxycontin
Dosage: 20 mg, unk
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Versed
Dosage: unk unk, see text
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Oxycodone HCL; Xanax; Valium
Possible Oxycontin side effects in 62 year old male
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: 62 year old male
Reactions: Narcolepsy, Restless Legs Syndrome, Agoraphobia, Fatigue, Road Traffic Accident, Overdose, Dizziness, Depression, Hallucination, Nausea, Paranoia, Drug Withdrawal Syndrome, Renal Failure, Dehydration, Asthenia, Sleep Apnoea Syndrome
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oxycontin
Dosage: dosing details unknown
Indication: Product Used FOR Unknown Indication
Suboxone
Indication: Drug Dependence
Start date: 2008-01-01
Suboxone
Dosage: tapered down to 16 mg daily
Indication: Drug Dependence
Possible Oxycontin side effects in 58 year old female
Reported by a physician from France on 2012-08-16
Patient: 58 year old female
Reactions: Disturbance in Attention
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Amitriptyline Hydrochloride
Indication: Product Used FOR Unknown Indication
End date: 2012-06-21
Cetirizine HCL
Administration route: Oral
Indication: Product Used FOR Unknown Indication
End date: 2012-06-21
Clonazepam
Administration route: Oral
Indication: Product Used FOR Unknown Indication
End date: 2012-06-21
Lyrica
Administration route: Oral
Indication: Product Used FOR Unknown Indication
End date: 2012-06-21
Oxycodone Hydrochloride
Administration route: Oral
Indication: Product Used FOR Unknown Indication
End date: 2012-06-21
Oxycontin
Administration route: Oral
Indication: Product Used FOR Unknown Indication
End date: 2012-06-21
Possible Oxycontin side effects in female
Reported by a pharmacist from Australia on 2012-08-15
Patient: female
Reactions: Death, Hospitalisation, Drug Administration Error
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Oxycontin
Possible Oxycontin side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-15
Patient: female
Reactions: Drug Ineffective, Neoplasm Malignant
Drug(s) suspected as cause:
Oxycontin
Dosage: 30 mg, q12h
Indication: Cancer Pain
Oxycontin
Dosage: 60 mg, tid
Possible Oxycontin side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-15
Patient: male
Reactions: Cellulitis, Restlessness, Tachycardia, Antibiotic Resistant Staphylococcus Test, Drug Abuse, Hyperhidrosis, Tremor, Anxiety, Psychotic Disorder, Skin Ulcer, Diarrhoea, Insomnia, Withdrawal Syndrome, Drug Dependence
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ipilimumab
Dosage: 295 mg, unk
Indication: Prostate Cancer
Start date: 2011-12-06
End date: 2012-05-29
Oxycodone HCL
Dosage: 10 mg, prn
Administration route: Oral
Indication: Back Pain
Start date: 2012-01-01
Oxycontin
Dosage: 20 mg, bid
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Placebo
Dosage: unk
Indication: Prostate Cancer
Start date: 2011-12-06
End date: 2012-05-29
Other drugs received by patient: Lisinopril; Humulin N; Sulfamethoxazole; Citalopram; Trazodone Hydrochloride; Aspirin; Buspar; Prednisone TAB; Paxil; Actos; Amaryl; Prednisone TAB; Zocor; Aleve; Celebrex; Metformin Hydrochloride; Titralac / 00183701 /; Triamcinolone; Humulin R; Novolin 70 / 30
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