This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Oncaspar (Pegaspargase) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (66)
Death (8)
Life Threatening Events (17)
Disability (5)
Reports by Reaction Type
Hypersensitivity (12),
Hypertriglyceridaemia (10),
Dyspnoea (8),
Pruritus (7),
Hypotension (7),
Pancreatitis (7),
Urticaria (6),
Pyrexia (6),
Infusion Related Reaction (6),
Death (5),
Blood Cholesterol Increased (5),
Cough (5)
Below are a few examples of reports where side effects / adverse reactions may be related to Oncaspar (Pegaspargase). For a complete list or a specific selection of reports, please use the links above.
Possible Oncaspar side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-24
Patient: male, weighing 121.9 kg (268.2 pounds)
Reactions: Pruritus, Unresponsive To Stimuli, Device Related Infection, Pyrexia, Candidiasis, Abscess Limb, Ventricular Extrasystoles, Metabolic Acidosis, Dyspnoea, Hypotension, Pancytopenia, Tremor, Convulsion, Respiratory Failure, Fungal Infection, Ventricular Tachycardia, Sepsis, Respiratory Arrest, Pulse Absent, Sinus Tachycardia, Hypertension, Feeling Abnormal, Cardiac Arrest, Escherichia Infection, Infusion Related Reaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Epinephrine
Dosage: 4 df, unk
Indication: Cardiac Arrest
Start date: 2012-07-14
End date: 2012-07-14
Cyclophosphamide
Dosage: daily for 5 days
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-06-19
End date: 2012-06-23
Oncaspar
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-07-02
End date: 2012-07-02
Epinephrine
Dosage: unk
Start date: 2012-07-14
End date: 2012-07-14
Clolar
Dosage: 74.4 mg, qd
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-06-19
End date: 2012-06-23
Etoposide
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-06-19
End date: 2012-06-23
Vincristine Sulfate
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-07-02
End date: 2012-07-02
Other drugs received by patient: Colace; Bactrim; Stomatitis Mouthwash; Prilosec; Lortab; Cymbalta; Ondansetron; Ambien
Possible Oncaspar side effects in
Reported by a physician from United States on 2012-08-15
Patient:
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Decadron
Dosage: 10 mg/m2, cyclic
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Doxorubicin Hydrochloride
Dosage: 60 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Hydrocortisone
Indication: Acute Lymphocytic Leukaemia
Vincristine
Dosage: 1.5 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Velcade
Dosage: 1.3 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in
Reported by a physician from United States on 2012-08-15
Patient:
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Methotrexate
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Velcade
Dosage: 1.3 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Hydrocortisone
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Decadron
Dosage: 10 mg/m2, cyclic
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Doxorubicin Hydrochloride
Dosage: 60 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Vincristine
Dosage: 1.5 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in
Reported by a physician from United States on 2012-08-15
Patient:
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Vincristine
Dosage: 1.5 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Doxorubicin Hydrochloride
Dosage: 60 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Hydrocortisone
Indication: Acute Lymphocytic Leukaemia
Velcade
Dosage: 1.3 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Decadron
Dosage: 10 mg/m2, cyclic
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in
Reported by a physician from United States on 2012-08-15
Patient:
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Hydrocortisone
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Velcade
Dosage: 1.3 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: unk, cyclic
Indication: Acute Lymphocytic Leukaemia
Decadron
Dosage: 10 mg/m2, cyclic
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Vincristine
Dosage: 1.5 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Doxorubicin Hydrochloride
Dosage: 60 mg/m2, cyclic
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in female
Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-07-30
Patient: female, weighing 49.0 kg (107.8 pounds)
Reactions: Death, Febrile Neutropenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Clofarabine
Dosage: 71 mg, qdx5
Start date: 2010-11-25
End date: 2010-11-29
Oncaspar
Dosage: 3206.3 iu, unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2010-11-01
End date: 2010-11-01
Oncaspar
Dosage: 3375 iu, unk
Start date: 2010-11-25
End date: 2010-11-25
Vincristine
Dosage: 2 mg, unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2010-11-25
End date: 2010-11-25
Clofarabine
Dosage: 71 mg, qdx5
Indication: Acute Lymphocytic Leukaemia
Start date: 2010-11-01
End date: 2010-11-05
Other drugs received by patient: Itraconazole; Valaciclovir
Possible Oncaspar side effects in male
Reported by a individual with unspecified qualification from United States on 2012-07-26
Patient: male, weighing 27.7 kg (60.9 pounds)
Reactions: Acute Pulmonary Oedema, Hypotension, Tachycardia, General Physical Health Deterioration, Respiratory Distress, Ascites, Heart Rate Decreased, Pleural Effusion, Septic Shock, Oxygen Saturation Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oncaspar
Dosage: 2500 iu
Vincristine Sulfate
Dosage: 3 mg
Methotrexate Sodium
Dosage: 15 mg
Cytarabine
Dosage: 70 mg
Dexamethasone
Dosage: 78 mg
Possible Oncaspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-12
Patient:
Reactions: Blood Triglycerides Increased
Drug(s) suspected as cause:
Dexamethasone
Dosage: 6 mg/m*2;qd;po
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Dosage: 2500 iu/m*2;x1;iv
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in 17 year old female
Reported by a physician from United States on 2012-06-08
Patient: 17 year old female, weighing 47.6 kg (104.7 pounds)
Reactions: Blood Bilirubin Increased, Pyrexia, Caecitis, Loss of Consciousness, Oedema Peripheral, Pulmonary Oedema, Hypocalcaemia, Acute Respiratory Distress Syndrome, Melaena, Hypertriglyceridaemia, Epistaxis, Dysphagia, Anaemia, Hyperglycaemia, General Physical Health Deterioration, Eating Disorder, Tremor, Cerebral Infarction, Depressed Level of Consciousness, Neutropenia, Confusional State, Dyskinesia, Somnolence, Splenic Infarction, Hypokalaemia, Pleural Effusion, White Blood Cell Count Decreased, Cerebrovascular Accident, Ascites, Diarrhoea, Hypophagia, Hypoalbuminaemia, Sinus Tachycardia, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Mercaptopurine
Dosage: 60mgm2 cyclic
Administration route: Oral
Indication: T-Cell Type Acute Leukaemia
Vincristine
Dosage: 1.5mgm2 cyclic
Indication: T-Cell Type Acute Leukaemia
Cyclophosphamide
Dosage: 1000mgm2 cyclic
Indication: T-Cell Type Acute Leukaemia
Methotrexate
Indication: T-Cell Type Acute Leukaemia
Oncaspar
Indication: T-Cell Type Acute Leukaemia
Nelarabine
Dosage: 650mgm2 cyclic
Indication: T-Cell Type Acute Leukaemia
Start date: 2012-04-13
Cytarabine
Dosage: 75mgm2 cyclic
Indication: T-Cell Type Acute Leukaemia
Dalteparin Sodium
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Nystatin; Lansoprazole; Insulin Aspart; Piperacillin and Tazobactam; Vancomycin; Voriconazole
Possible Oncaspar side effects in 21 year old female
Reported by a physician from United States on 2012-06-07
Patient: 21 year old female
Reactions: Abdominal Pain, Hyperbilirubinaemia, Nausea, Hyperglycaemia, Malnutrition, Hepatic Steatosis, Cholelithiasis, Fatigue, Activities of Daily Living Impaired, Hepatotoxicity, Cholangitis, Pancreatitis, Asthenia, Mobility Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Vincristine Sulfate
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Indication: Acute Lymphocytic Leukaemia
Daunorubicin HCL
Indication: Acute Lymphocytic Leukaemia
Prednisone TAB
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in female
Reported by a physician from United States on 2012-05-25
Patient: female
Reactions: Lung Consolidation, Osteonecrosis, Joint Range of Motion Decreased, Arthralgia, Limb Asymmetry, Gait Disturbance
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Cytarabine
Dosage: intrathecal
Indication: Acute Lymphocytic Leukaemia
Daunorubicin HCL
Indication: Acute Lymphocytic Leukaemia
Doxorubicin HCL
Indication: Acute Lymphocytic Leukaemia
Cyclophosphamide
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Indication: Acute Lymphocytic Leukaemia
Vincristine Sulfate
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Dosage: intrathecal
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: intrathecal
Indication: Acute Lymphocytic Leukaemia
Oncaspar
Indication: Acute Lymphocytic Leukaemia
Thioguanine
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in 10 year old male
Reported by a physician from United States on 2012-05-24
Patient: 10 year old male, weighing 22.3 kg (49.1 pounds)
Reactions: Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Doxorubicin HCL
Dosage: 27 mg, qd on day 1 and 5
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-03-31
End date: 2012-05-01
Methylprednisolone Acetate
Dosage: 9.7 mg, q8h on day 4 to day 32
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-05-03
Etoposide
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-05-10
Afinitor
Dosage: 2 mg, qd on day 1 to day 32
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-03-31
End date: 2012-05-01
Oncaspar
Dosage: 2275 iu, qd on days 4 to 32
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-03-31
End date: 2012-05-01
Vincristine
Dosage: 1.4 mg, qd on day 4, 11, 18 and 25
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-03-31
End date: 2012-05-01
Cytoxan
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-05-10
Other drugs received by patient: Leucovorin Calcium; Ondansetron; Senna-Mint WAF; Colace; Sulfamethoxypyrazine / Trimethoprim; Ondansetron; Concerta; Calcium Carbonate; Clonidine
Possible Oncaspar side effects in 7 year old female
Reported by a individual with unspecified qualification from United States on 2012-05-17
Patient: 7 year old female, weighing 39.0 kg (85.8 pounds)
Reactions: Retching, Nausea, Hypophagia, Hypertriglyceridaemia, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Velcade
Dosage: 1.3 mg/m**2; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
End date: 2012-04-17
Doxorubicin HCL
Dosage: 60 mg/m**2;qd;iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
End date: 2012-03-01
Oncaspar
Dosage: 2500 iu/m**2; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
End date: 2012-03-22
Cytarabine
Dosage: 70 mg;x1;inth
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
End date: 2012-02-28
Vincristine
Dosage: 1.5 mg/m**2; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
End date: 2012-03-22
Prednisone TAB
Dosage: 20 mg/m**2;qd;po
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
End date: 2012-03-01
Methotrexate
Dosage: 500 mg/m**2; inth; 4500 mg/m**2; iv
Indication: Acute Lymphocytic Leukaemia
End date: 2012-04-10
Methotrexate
Dosage: 500 mg/m**2; inth; 4500 mg/m**2; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-28
Methotrexate
Dosage: 500 mg/m**2; inth; 4500 mg/m**2; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-04-10
End date: 2012-04-14
Possible Oncaspar side effects in 13 year old female
Reported by a physician from United States on 2012-04-25
Patient: 13 year old female, weighing 64.8 kg (142.6 pounds)
Reactions: Alanine Aminotransferase Increased, Acute Lymphocytic Leukaemia Recurrent, Mental Status Changes, Cerebral Artery Occlusion, Hypokalaemia, Gamma-Glutamyltransferase Increased, Aspartate Aminotransferase Increased, Pancreatitis, Depressed Level of Consciousness, Neurological Symptom, Hypertriglyceridaemia
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Prednisone
Dosage: 20 mg/m2, bid, po
Administration route: Oral
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-11
End date: 2012-02-18
Velcade
Dosage: 1.3 mg/m2, x1, iv
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-11
End date: 2012-02-18
Oncaspar
Dosage: 2500 iu/m2,x1
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-11
End date: 2012-03-02
Cytarabine
Other drugs received by patient: Doxorubicin HCL; Dalteparin Sodium; Vincristine; Methotrexate
Possible Oncaspar side effects in 17 year old male
Reported by a physician from United States on 2012-04-25
Patient: 17 year old male, weighing 45.0 kg (99.0 pounds)
Reactions: Back Pain, Gastrointestinal Haemorrhage, Hypotension, Malnutrition, Neoplasm Progression, Haemorrhoidal Haemorrhage, Convulsion, Leukaemia, Cachexia, Diarrhoea, NO Therapeutic Response, Sepsis, Nervous System Disorder, Altered State of Consciousness
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Methotrexate
Dosage: ;x1;inth
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-03-05
End date: 2012-03-05
Methotrexate
Dosage: ;x1;inth
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-20
End date: 2012-02-20
Cytarabine
Dosage: ;x1;inth
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-20
End date: 2012-02-20
Prednisone
Dosage: 20 mg/m**2; po
Administration route: Oral
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-20
End date: 2012-03-14
Vincristine
Dosage: 1.5 mg/m**2;x1;iv
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-20
End date: 2012-02-20
Vincristine
Dosage: 1.5 mg/m**2;x1;iv
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-03-12
End date: 2012-03-12
Oncaspar
Dosage: 2500 iu/m**2;qw;im
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-20
End date: 2012-03-12
Doxorubicin HCL
Dosage: 60 ug/m**2;x1;iv
Indication: B Precursor Type Acute Leukaemia
Velcade
Dosage: 1.3 mg/m**2;x1;iv
Indication: B Precursor Type Acute Leukaemia
Start date: 2012-02-20
End date: 2012-02-20
Other drugs received by patient: Keppra
Possible Oncaspar side effects in 19 year old female
Reported by a physician from United States on 2012-04-24
Patient: 19 year old female, weighing 160.0 kg (352.0 pounds)
Reactions: Axillary Vein Thrombosis, Pyrexia, High Density Lipoprotein Decreased, Very LOW Density Lipoprotein Increased, Vena Cava Thrombosis, Thrombophlebitis, Blood Cholesterol Increased, Hypertriglyceridaemia
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Oncaspar
Dosage: 4500 iu;x1; 2125 iu;x1;
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-12-01
End date: 2011-12-01
Oncaspar
Dosage: 4500 iu;x1; 2125 iu;x1;
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-01-17
End date: 2012-01-17
Oncaspar
Dosage: 4500 iu;x1; 2125 iu;x1;
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-14
End date: 2012-02-14
Oncaspar
Possible Oncaspar side effects in 13 year old female
Reported by a physician from United States on 2012-04-06
Patient: 13 year old female, weighing 83.0 kg (182.6 pounds)
Reactions: Pancreatitis Acute, Diabetes Mellitus, Disseminated Intravascular Coagulation, Hepatic Failure, Renal Failure, Pancreatitis Necrotising, Respiratory Failure, Pancreatic Pseudocyst, Pleural Effusion, Pancreatic Insufficiency
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Oncaspar
Oncaspar
Dosage: 4925 iu; x1; sc
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-11-07
End date: 2011-11-07
Oncaspar
Dosage: 4925 iu; x1; sc
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-12-20
End date: 2011-12-20
Oncaspar
Dosage: 4925 iu; x1; sc
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-01-17
End date: 2012-01-17
Other drugs received by patient: Mercaptopurine; Zofran; Methotrexate; Cyclophosphamide; Cytarabine
Possible Oncaspar side effects in 15 year old male
Reported by a consumer/non-health professional from United States on 2012-04-03
Patient: 15 year old male, weighing 110.0 kg (242.0 pounds)
Reactions: Hypersensitivity, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytarabine
Dosage: last dose on 24nov09; 60 mg it:15oct09
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Oncaspar
Dosage: lats dose:05oct2009
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Cyclophosphamide
Dosage: last dose on 27nov09. 2352mg:05oct2009
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Methotrexate
Dosage: last dose on 09nov2009: 24000 mg iv mtx
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Daunorubicin HCL
Dosage: last dose:02oct2009
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Vincristine Sulfate
Dosage: last dose:15oct2009
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Etoposide
Dosage: last dose on 27nov09.
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Asparaginase
Dosage: last dose on 06jan10.
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Dexamethasone
Dosage: last dose:21oct2009
Start date: 2009-04-08
Sprycel
Dosage: last dose on 27dec09. 1820mg:14oct2009
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Hydrocortisone
Dosage: last dose on 24nov2009, 15oct2009
Indication: Acute Lymphocytic Leukaemia
Start date: 2009-04-08
Possible Oncaspar side effects in 18 year old male
Reported by a physician from United States on 2012-04-03
Patient: 18 year old male, weighing 126.4 kg (278.1 pounds)
Reactions: White Blood Cell Count Decreased, Abdominal Pain, Metabolic Acidosis, Clostridium Test Positive, Urine Output Decreased, Hypotension, Hyponatraemia, Capillary Leak Syndrome, Platelet Count Decreased, Septic Shock
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Oncaspar
Dosage: 2500 iu;x1;iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-24
End date: 2012-03-02
Doxorubicin HCL
Dosage: 60 mg/m**2;x1;iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-24
End date: 2012-02-24
Velcade
Dosage: 1.3 mg/m**2; qd; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-24
End date: 2012-03-02
Vincristine
Dosage: 1.5 mg/m**2;qd;iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-24
End date: 2012-03-02
Prednisone TAB
Dosage: 20 mg/m**2;qd;po
Administration route: Oral
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-24
End date: 2012-03-04
Cytarabine
Dosage: 70 mg;x1;inth
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-02-24
Hydrocortisone
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Dosage: inth
Indication: Acute Lymphocytic Leukaemia
Possible Oncaspar side effects in 15 year old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 15 year old female, weighing 49.0 kg (107.8 pounds)
Reactions: LIP Swelling, Hypersensitivity, Pruritus, Urticaria
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Oncaspar
Other drugs received by patient: Vincristine; Mercaptopurine; Cotrim
Possible Oncaspar side effects in 29 month old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 29 month old female, weighing 15.0 kg (33.0 pounds)
Reactions: LIP Swelling, Hypersensitivity, Swelling Face
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oncaspar
Possible Oncaspar side effects in 8 year old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 8 year old female, weighing 26.0 kg (57.2 pounds)
Reactions: Hypersensitivity, Vomiting, Nausea, Chills, Pyrexia
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Oncaspar
Possible Oncaspar side effects in 10 year old male
Reported by a pharmacist from United States on 2012-04-02
Patient: 10 year old male, weighing 44.0 kg (96.8 pounds)
Reactions: Face Oedema, Vomiting, Anaphylactic Reaction, Urticaria, Wheezing, Blood Pressure Decreased
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Oncaspar
Dosage: ;x1; iv, 3300 iu;x1; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-07-07
End date: 2011-07-07
Oncaspar
Dosage: ;x1; iv, 3300 iu;x1; iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-05-15
End date: 2011-05-15
Other drugs received by patient: Cotrim
Possible Oncaspar side effects in 12 year old male
Reported by a pharmacist from United States on 2012-04-02
Patient: 12 year old male, weighing 38.0 kg (83.6 pounds)
Reactions: Hypersensitivity, Pruritus, Dyspnoea, Laryngeal Oedema, Cough
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Oncaspar
Dosage: 3150 iu;x1;iv
Indication: Acute Lymphocytic Leukaemia Recurrent
Start date: 2011-10-23
End date: 2011-10-23
Oncaspar
Other drugs received by patient: Cytarabine; Pentamidine Isethionate; Cetirizine Scopolamine / 00008701 /
Possible Oncaspar side effects in 9 year old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 9 year old female, weighing 25.0 kg (55.0 pounds)
Reactions: LIP Swelling, Hypersensitivity, Urticaria, Rash
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oncaspar
Possible Oncaspar side effects in 22 month old male
Reported by a pharmacist from United States on 2012-04-02
Patient: 22 month old male, weighing 13.0 kg (28.6 pounds)
Reactions: Agitation, Dyspnoea, Anaphylactic Reaction, Erythema, Cough
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Oncaspar
Possible Oncaspar side effects in 4 year old male
Reported by a pharmacist from United States on 2012-04-02
Patient: 4 year old male, weighing 17.0 kg (37.4 pounds)
Reactions: Hypersensitivity, Dyspnoea, Urticaria, Respiratory Distress, Cough
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Oncaspar
Other drugs received by patient: Ranitidine; CO-Trimazole; Dexamethasone
Possible Oncaspar side effects in 18 year old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 18 year old female, weighing 66.7 kg (146.7 pounds)
Reactions: Hypersensitivity, Chest Discomfort, Wheezing, Cough
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Oncaspar
Dosage: 4650 iu;x1;iv
Indication: Acute Lymphocytic Leukaemia
Start date: 2011-10-17
End date: 2011-10-17
Oncaspar
Other drugs received by patient: Cotrimaxazole; Vincristine; Daunorubicin HCL; Acyclovir; Prednisone; Ondansetron; Cefepime; Ranitidine
Possible Oncaspar side effects in 7 year old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 7 year old female, weighing 22.0 kg (48.4 pounds)
Reactions: Hypersensitivity, Swelling Face, Eye Swelling
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Oncaspar
Possible Oncaspar side effects in 15 year old female
Reported by a pharmacist from United States on 2012-04-02
Patient: 15 year old female, weighing 62.0 kg (136.4 pounds)
Reactions: Hypersensitivity, Chest Discomfort, Throat Tightness, Cough
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Oncaspar
Other drugs received by patient: Methotrexate; Vincristine
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