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Nplate (Romiplostim Subcutaneous) - Therapeutic Response Decreased - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Therapeutic Response Decreased (281)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nplate (Romiplostim Subcutaneous) where reactions include therapeutic response decreased. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 281   Next >>

Possible Nplate side effects in 49 year old male

Reported by a physician from Egypt on 2012-08-27

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Therapeutic Response Decreased, Surgery, Post Procedural Complication, Bronchitis, Nosocomial Infection, Preoperative Care

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate
    Dosage: 2 mug/kg, qwk

Nplate
    Dosage: 7 mug/kg, qwk

Nplate
    Dosage: 1 mug/kg, qwk
    Indication: Idiopathic Thrombocytopenic Purpura

Other drugs received by patient: Kanakion; Folic Acid; Selenium ACE



Possible Nplate side effects in 62 year old male

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: 62 year old male, weighing 91.1 kg (200.4 pounds)

Reactions: Therapeutic Response Decreased, Arthralgia, Treatment Failure

Drug(s) suspected as cause:
Nplate
    Dosage: 10 mug, qwk
    Indication: Autoimmune Thrombocytopenia
    Start date: 2011-11-28
    End date: 2012-07-19

Nplate
    Dosage: 9 mug/kg, unk

Other drugs received by patient: Losartan Potassium



Possible Nplate side effects in 14 year old female

Reported by a physician from United States on 2012-08-23

Patient: 14 year old female, weighing 99.6 kg (219.1 pounds)

Reactions: Abdominal Pain, Viral Infection, Body Temperature Increased, Nausea, Blood Lactate Dehydrogenase Increased, Underdose, Purpura, Pyrexia, Haemolysis, RED Blood Cell Morphology Abnormal, Therapeutic Response Decreased, Injection Site Extravasation, Poor Venous Access, Blood Smear Test Abnormal, Menorrhagia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate
    Dosage: 300 mug, qwk
    Start date: 2011-02-07
    End date: 2011-02-17

Nplate
    Dosage: 600 mug, qwk
    Start date: 2011-03-10
    End date: 2011-03-17

Nplate
    Dosage: 100 mug, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2010-12-14
    End date: 2010-12-28

Nplate
    Dosage: 250 mug, qwk
    Start date: 2011-01-31
    End date: 2011-02-07

Nplate
    Dosage: 500 mug, qwk
    Start date: 2011-03-02
    End date: 2011-03-02

Nplate
    Dosage: 200 mug, qwk
    Start date: 2010-12-28
    End date: 2011-01-04

Nplate
    Dosage: 200 mug, qwk
    Start date: 2011-01-24
    End date: 2011-01-31

Nplate
    Dosage: 400 mug, qwk
    Start date: 2011-02-17
    End date: 2011-02-17

Other drugs received by patient: Prednisone TAB; Prednisone TAB; Prednisone TAB; Prednisone TAB; Dexamethasone; Prednisone TAB



Possible Nplate side effects in female

Reported by a physician from United Kingdom on 2012-08-22

Patient: female

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 82 year old female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: 82 year old female, weighing 41.4 kg (91.0 pounds)

Reactions: Therapeutic Response Decreased, Thrombocytopenia

Drug(s) suspected as cause:
Nplate
    Dosage: 4 mug/kg, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2011-11-15

Nplate
    Dosage: 168 mug, qwk
    End date: 2012-08-07

Other drugs received by patient: Imdur; Nexium; Magnesium Oxide; Iviglob-EX; Iviglob-EX; Boniva; Aspirin; Vitamin D; Calcium Carbonate; Rituxan; Metoprolol Tartrate; Rituxan; Rituxan; Rituxan; Iviglob-EX; Capoten; Lipitor; Rituxan; Iviglob-EX



Possible Nplate side effects in male

Reported by a physician from United Kingdom on 2012-08-17

Patient: male, weighing 100.0 kg (220.0 pounds)

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate

Other drugs received by patient: NEO-Mercazole TAB



Possible Nplate side effects in 52 year old male

Reported by a physician from United States on 2012-08-17

Patient: 52 year old male

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 82 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 82 year old female

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate
    Dosage: 4 mug/kg, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2011-11-15

Nplate
    Dosage: 1 mug/kg, unk

Other drugs received by patient: Magnesium Oxide; Metoprolol; Imdur; Capoten; Calcium Carbonate; Vitamin D; Lipitor; Nexium; Boniva; Aspirin



Possible Nplate side effects in 5 year old male

Reported by a physician from Egypt on 2012-08-10

Patient: 5 year old male

Reactions: Therapeutic Response Decreased, Bronchitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate
    Dosage: 7 mug/kg, qwk

Nplate
    Dosage: 1 mug/kg, qwk
    Indication: Idiopathic Thrombocytopenic Purpura

Nplate
    Dosage: 2 mug/kg, qwk



Possible Nplate side effects in 15 year old female

Reported by a physician from United States on 2012-08-09

Patient: 15 year old female, weighing 99.6 kg (219.1 pounds)

Reactions: RED Blood Cell Morphology Abnormal, Therapeutic Response Decreased, Injection Site Extravasation, Blood Lactate Dehydrogenase Increased, Underdose, Blood Smear Test Abnormal, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate
    Dosage: 100 mug, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2010-12-14
    End date: 2010-12-28

Nplate
    Dosage: 200 mug, qwk
    Start date: 2010-12-28
    End date: 2011-01-04

Nplate
    Dosage: 200 mug, qwk
    Start date: 2011-01-24
    End date: 2011-01-31

Nplate
    Dosage: 300 mug, qwk
    Start date: 2011-02-07
    End date: 2011-02-17

Nplate
    Dosage: 500 mug, qwk
    Start date: 2011-03-02
    End date: 2011-03-02

Nplate
    Dosage: 250 mug, qwk
    Start date: 2011-01-31
    End date: 2011-02-07

Nplate
    Dosage: 400 mug, qwk
    Start date: 2011-02-17
    End date: 2011-02-17

Nplate
    Dosage: 600 mug, qwk
    Start date: 2011-03-10
    End date: 2011-03-17

Other drugs received by patient: Prednisone TAB; Prednisone TAB; Prednisone TAB; Prednisone TAB; Prednisone TAB; Dexamethasone



Possible Nplate side effects in 62 year old male

Reported by a physician from United States on 2012-08-06

Patient: 62 year old male, weighing 91.1 kg (200.4 pounds)

Reactions: Therapeutic Response Decreased, Arthralgia, Treatment Failure

Drug(s) suspected as cause:
Nplate
    Dosage: unk
    Start date: 2011-11-01
    End date: 2012-06-01

Nplate
    Dosage: 10 mug, qwk
    Indication: Autoimmune Thrombocytopenia
    Start date: 2011-11-28
    End date: 2012-07-19

Other drugs received by patient: Losartan Potassium



Possible Nplate side effects in 70 year old male

Reported by a physician from Hungary on 2012-08-06

Patient: 70 year old male

Reactions: Therapeutic Response Decreased, Gastrointestinal Haemorrhage, Mouth Haemorrhage, Haemorrhage, Platelet Count Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 74 year old male

Reported by a physician from Portugal on 2012-08-06

Patient: 74 year old male, weighing 60.0 kg (132.0 pounds)

Reactions: Therapeutic Response Decreased, Gingival Bleeding, Ecchymosis, Petechiae, Platelet Count Increased, Thrombocytopenia, Epistaxis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate
    Dosage: 490 mug, unk

Nplate
    Dosage: 600 mug, qwk
    Indication: Thrombocytopenic Purpura
    Start date: 2011-12-16

Other drugs received by patient: Rituximab



Possible Nplate side effects in 56 year old male

Reported by a physician from United States on 2012-08-02

Patient: 56 year old male

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate

Other drugs received by patient: Lamivudine; Zidovudine; Iron; Tylenol (Caplet); Efavirenz; Folic Acid; Colace



Possible Nplate side effects in 51 year old male

Reported by a consumer/non-health professional from United States on 2012-08-02

Patient: 51 year old male, weighing 160.5 kg (353.2 pounds)

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate

Other drugs received by patient: Augmentin '125'; Lasix; Immune Globulin NOS; Ambien



Possible Nplate side effects in female

Reported by a physician from United States on 2012-08-01

Patient: female

Reactions: Therapeutic Response Decreased, Drug Ineffective, Platelet Count Decreased

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 61 year old female

Reported by a physician from United States on 2012-08-01

Patient: 61 year old female, weighing 113.0 kg (248.6 pounds)

Reactions: Therapeutic Response Decreased, Platelet Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate

Other drugs received by patient: Metformin Hydrochloride; Folic Acid; Prednisone; Insulin; Protonix; Sertraline Hydrochloride



Possible Nplate side effects in 65 year old female

Reported by a pharmacist from Spain on 2012-08-01

Patient: 65 year old female, weighing 118.0 kg (259.6 pounds)

Reactions: Therapeutic Response Decreased, Hypersensitivity

Drug(s) suspected as cause:
Nplate
    Dosage: unk unk, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2012-03-13

Nplate
    Dosage: 236 mug, unk
    Start date: 2012-07-12

Nplate
    Dosage: unk
    Start date: 2011-09-14
    End date: 2012-02-23

Nplate
    Dosage: unk

Other drugs received by patient: Eltrombopag; Prednisone; Roname; Roname; Tranexamic Acid; Colemin; Sutrilneo; Rituximab; Eltrombopag; Omeprazole; Candesartan Cilexetil; Loratadina; Tramadol HCL; Acetaminophen



Possible Nplate side effects in 40 year old female

Reported by a physician from Spain on 2012-07-24

Patient: 40 year old female

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 29 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-23

Patient: 29 year old male, weighing 76.2 kg (167.6 pounds)

Reactions: Therapeutic Response Decreased, Bone Pain, Platelet Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 44 year old female

Reported by a physician from United States on 2012-07-19

Patient: 44 year old female, weighing 87.5 kg (192.5 pounds)

Reactions: Therapeutic Response Decreased, Platelet Count Abnormal

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 50 year old female

Reported by a physician from United States on 2012-07-12

Patient: 50 year old female, weighing 69.9 kg (153.8 pounds)

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate
    Dosage: 62 mug, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2008-09-29
    End date: 2009-05-21

Nplate
    Dosage: 373 mug/kg, unk
    End date: 2009-07-06

Nplate
    Dosage: unk
    Start date: 2008-10-06



Possible Nplate side effects in

Reported by a physician from United Kingdom on 2012-07-11

Patient:

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in male

Reported by a physician from Canada on 2012-07-09

Patient: male

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate

Other drugs received by patient: Immune Globulin NOS



Possible Nplate side effects in 50 year old female

Reported by a physician from United States on 2012-07-09

Patient: 50 year old female, weighing 69.9 kg (153.8 pounds)

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate
    Dosage: unk
    Start date: 2008-10-06

Nplate
    Dosage: 373 mug/kg, unk
    End date: 2009-07-06

Nplate
    Dosage: 62 mug, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2008-09-29
    End date: 2009-05-21



Possible Nplate side effects in 62 year old male

Reported by a physician from United States on 2012-07-05

Patient: 62 year old male

Reactions: Therapeutic Response Decreased

Drug(s) suspected as cause:
Nplate
    Dosage: 10 mug, qwk

Nplate
    Dosage: unk
    Indication: Autoimmune Thrombocytopenia
    Start date: 2011-11-01
    End date: 2012-06-01



Possible Nplate side effects in female

Reported by a physician from United States on 2012-07-05

Patient: female

Reactions: Therapeutic Response Decreased, Injection Site Extravasation, Underdose, Blood Smear Test Abnormal

Drug(s) suspected as cause:
Nplate



Possible Nplate side effects in 53 year old male

Reported by a consumer/non-health professional from United States on 2012-07-04

Patient: 53 year old male, weighing 78.0 kg (171.6 pounds)

Reactions: Therapeutic Response Decreased, Therapeutic Response Unexpected

Drug(s) suspected as cause:
Nplate
    Dosage: 500 mug, unk
    Start date: 2010-02-04
    End date: 2010-02-04

Nplate
    Dosage: 510 mug, unk
    Start date: 2010-04-08
    End date: 2010-04-08

Nplate
    Dosage: 672 mug, unk
    Start date: 2010-05-06
    End date: 2010-05-06

Nplate
    Dosage: 850 mug, qwk
    Start date: 2010-12-09
    End date: 2011-08-04

Nplate
    Dosage: 160 mug, unk
    Start date: 2010-01-07
    End date: 2010-01-07

Nplate
    Dosage: 670 mug, qwk
    Start date: 2010-10-21
    End date: 2010-10-29

Nplate
    Dosage: 560 mug, unk
    Start date: 2010-02-11
    End date: 2010-02-11

Nplate
    Dosage: 510 mug, unk
    Start date: 2010-04-08
    End date: 2010-04-08

Nplate
    Dosage: 672 mug, qwk
    Start date: 2010-03-18
    End date: 2010-04-01

Nplate
    Dosage: 250 mug, unk
    Start date: 2010-01-14
    End date: 2010-01-14

Nplate
    Dosage: 320 mug, qwk
    Start date: 2010-01-21
    End date: 2010-01-21

Nplate
    Dosage: 400 mug, unk
    Start date: 2010-01-28
    End date: 2010-01-28

Nplate
    Dosage: 672 mug, qwk
    Start date: 2010-02-25
    End date: 2010-03-04

Nplate
    Dosage: 560 mug, qwk
    Start date: 2010-04-15
    End date: 2010-04-29

Nplate
    Dosage: 9 mug/kg, unk
    Start date: 2010-05-13

Nplate
    Dosage: 750 mug, qwk
    Start date: 2010-05-20
    End date: 2010-10-14

Nplate
    Dosage: 80 mug, qwk
    Indication: Idiopathic Thrombocytopenic Purpura
    Start date: 2009-12-31
    End date: 2009-12-31

Nplate
    Dosage: 672 mug, unk
    Start date: 2010-05-06
    End date: 2010-05-06

Nplate
    Dosage: 560 mug, qwk
    Start date: 2010-04-15
    End date: 2010-04-29

Nplate
    Dosage: 750 mug, qwk
    Start date: 2010-11-04
    End date: 2010-12-02

Other drugs received by patient: Niacin; Tylenol (Caplet); Rituxan; Benadryl; Danazol; Danazol; Zocor



Possible Nplate side effects in 59 year old female

Reported by a pharmacist from United States on 2012-07-02

Patient: 59 year old female, weighing 93.9 kg (206.5 pounds)

Reactions: Diabetes Mellitus, Haemorrhage, Swollen Tongue, Therapeutic Response Decreased, Iron Deficiency Anaemia, Diabetic Neuropathy, Oedema Mouth, Candidiasis

Drug(s) suspected as cause:
Nplate

Other drugs received by patient: Eltrombopag; Corticosteroids



Possible Nplate side effects in 59 year old male

Reported by a pharmacist from United States on 2012-07-02

Patient: 59 year old male, weighing 97.0 kg (213.4 pounds)

Reactions: Therapeutic Response Decreased, Haemolytic Anaemia, Thrombocytopenia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Nplate

Nplate

Nplate

Nplate
    Dosage: 7 mug/kg, unk
    Indication: Thrombocytopenia
    Start date: 2012-03-16

Nplate

Nplate

Other drugs received by patient: Budesonide; Posaconazole; Prednisone TAB; Atovaquone; Acyclovir



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