This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Noxafil (Posaconazole) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (72)
Death (16)
Life Threatening Events (15)
Disability (5)
Reports by Reaction Type
Drug Interaction (14),
Sinoatrial Block (7),
Atrioventricular Block Second Degree (6),
Myositis (6),
Nodal Arrhythmia (5),
Septic Shock (5),
Sinus Tachycardia (5),
Sinus Bradycardia (4),
Diabetes Mellitus (3),
Overdose (3),
Neuropathy Peripheral (3),
Thrombocytopenia (3)
Below are a few examples of reports where side effects / adverse reactions may be related to Noxafil (Posaconazole). For a complete list or a specific selection of reports, please use the links above.
Possible Noxafil side effects in
Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-08-23
Patient:
Reactions: Hepatotoxicity, Drug-Induced Liver Injury
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Acetaminophen
Dosage: 1000 mg, tid
Indication: Product Used FOR Unknown Indication
Start date: 2012-01-30
End date: 2012-02-01
Noxafil
Dosage: 200 mg, qid
Administration route: Oral
Indication: Prophylaxis
Start date: 2012-01-25
End date: 2012-02-02
Other drugs received by patient: Fosamax; Urso Falk; Calcimagon D3; Nexium; Ciprofloxacin; Valtrex; Meticorten
Possible Noxafil side effects in
Reported by a physician from United States on 2012-08-23
Patient:
Reactions: Malabsorption, Overdose, Vomiting, Nausea, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient possibly interacting with the suspect drug: Cyclosporine
Famotidine
Dosage: unk
Nifedipine
Noxafil
Dosage: 800 mg, q6h
Administration route: Oral
Noxafil
Dosage: 600 mg, q6h
Noxafil
Dosage: 400 mg, q4h
Pantoprazole
Dosage: unk
Phenytoin
Dosage: unk
Indication: Convulsion Prophylaxis
Sirolimus
Sucralfate
Dosage: unk
Administration route: Oral
Sucralfate
Dosage: unk
Other drugs received by patient: Micafungin
Possible Noxafil side effects in
Reported by a physician from United States on 2012-08-23
Patient:
Reactions: Malabsorption, Overdose, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient possibly interacting with the suspect drug: Famotidine
Noxafil
Dosage: 1500 mg qd
Noxafil
Dosage: 120-300 mg/kg/day
Noxafil
Dosage: 3000 mg/kg/day
Pantoprazole
Sucralfate
Other drugs received by patient: Amphotericin B (+) L-(Alpha)-Dimyristoylphosphatidylcholine (+) L-(Alp; Amphotericin B (+) L-(Alpha)-Dimyristoylphosphatidylcholine (+) L-(Alp; Amphotericin B (+) L-(Alpha)-Dimyristoylphosphatidylcholine (+) L-(Alp; Amphotericin B; Micafungin; Amphotericin B (+) L-(Alpha)-Dimyristoylphosphatidylcholine (+) L-(Alp
Possible Noxafil side effects in
Reported by a physician from Austria on 2012-08-23
Patient:
Reactions: Multi-Organ Failure, Diarrhoea, Graft Versus Host Disease
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Corticosteroids (Unspecified); Mycophenolate Mefetil; Itraconazole; Amphotericin B; Methylprednisolone; Remicade; Voriconazole; Caspofungin Acetate
Possible Noxafil side effects in
Reported by a consumer/non-health professional from Germany on 2012-08-10
Patient:
Reactions: Congestive Cardiomyopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Sulfamethoxazole and Trimethoprim
Possible Noxafil side effects in
Reported by a physician from United States on 2012-08-09
Patient:
Reactions: Fusarium Infection
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in
Reported by a physician from United States on 2012-08-09
Patient:
Reactions: Abdominal Pain, Agitation, Abasia, Drug Interaction, Muscular Weakness, Hyponatraemia, Constipation, Paraesthesia, Convulsion, Neurotoxicity, Peroneal Nerve Palsy, Inappropriate Antidiuretic Hormone Secretion, Areflexia, Brain Oedema
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient possibly interacting with the suspect drug: Vincristine Sulfate
Indication: Prophylaxis
Possible Noxafil side effects in
Reported by a individual with unspecified qualification from United States on 2012-08-07
Patient:
Reactions: Disease Progression
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Amphotericin B
Possible Noxafil side effects in
Reported by a physician from Germany on 2012-08-02
Patient:
Reactions: Congestive Cardiomyopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Sulfamethoxazole and Trimethoprim
Possible Noxafil side effects in
Reported by a physician from Denmark on 2012-07-30
Patient:
Reactions: Neurotoxicity, Hypokinesia, Pain in Extremity, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient possibly interacting with the suspect drug: Oncovin
Dosage: 2 mg, qw
Start date: 2012-04-17
End date: 2012-05-01
Other drugs received by patient: Prednisolone; Vancomycin; Imatinib Mesylate; Meropenem
Possible Noxafil side effects in
Reported by a health professional (non-physician/pharmacist) from France on 2012-07-26
Patient:
Reactions: Pancreatitis Acute
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Dosage: 200 mg, tid
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2012-01-12
End date: 2012-01-30
Tazobactam
Dosage: 4 g, tid
Indication: Pyrexia
Start date: 2012-01-20
End date: 2012-02-10
Other drugs received by patient: Furosemide; Polaramine; Acetaminophen; Vancomycin; Idarubicin Hydrochloride; Vesanoid; Lutenyl; Cytarabine; Fungizone; Zolpidem Tartrate
Possible Noxafil side effects in
Reported by a physician from Germany on 2012-07-20
Patient:
Reactions: Acute Hepatic Failure
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ciprofloxacin
Dosage: 500 mg, bid
Administration route: Oral
Indication: Antibiotic Prophylaxis
Start date: 2011-12-13
End date: 2012-01-05
Exjade
Dosage: 125 mg, bid
Administration route: Oral
Indication: Transfusion Reaction
Start date: 2011-12-20
End date: 2012-01-05
Noxafil
Dosage: 400 mg, bid
Administration route: Oral
Indication: Antifungal Prophylaxis
Start date: 2011-12-20
End date: 2011-12-27
Other drugs received by patient: Acyclovir; Atacand; Cotrim DS; Pantoprazole
Possible Noxafil side effects in
Reported by a physician from United States on 2012-07-20
Patient:
Reactions: Fusarium Infection
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in
Reported by a physician from Spain on 2012-07-18
Patient:
Reactions: Overdose
Drug(s) suspected as cause:
Noxafil
Administration route: Oral
Indication: Fungal Infection
Posaconazole
Dosage: unk
Indication: Fungal Infection
Start date: 2012-06-30
Possible Noxafil side effects in
Reported by a consumer/non-health professional from United States on 2012-07-16
Patient:
Reactions: Arthralgia
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in
Reported by a individual with unspecified qualification from United States on 2012-07-10
Patient:
Reactions: Disease Progression
Adverse event resulted in: death, disablity
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Amphotericin B
Possible Noxafil side effects in male
Reported by a pharmacist from United Kingdom on 2012-07-05
Patient: male
Reactions: Malaise
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in male
Reported by a physician from United Kingdom on 2012-06-27
Patient: male
Reactions: Neuropathy Peripheral, Neoplasm Malignant
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Acyclovir; Septra
Possible Noxafil side effects in female
Reported by a physician from United Kingdom on 2012-06-22
Patient: female
Reactions: Fungal Infection
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Noxafil
Dosage: 600 mg;qd;po
Administration route: Oral
Indication: Fungal Infection
Noxafil
Dosage: 600 mg;qd;po
Administration route: Oral
Indication: Prophylaxis
Possible Noxafil side effects in 22 year old male
Reported by a physician from France on 2012-06-21
Patient: 22 year old male
Reactions: Intentional Overdose, Urticaria, Purpura
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in 62 year old female
Reported by a consumer/non-health professional from United States on 2012-06-14
Patient: 62 year old female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in 42 year old male
Reported by a physician from Thailand on 2012-06-04
Patient: 42 year old male
Reactions: Septic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in male
Reported by a physician from United States on 2012-06-01
Patient: male
Reactions: Drug Level Changed, Fusarium Infection
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in 43 year old male
Reported by a physician from Thailand on 2012-05-30
Patient: 43 year old male
Reactions: Haemorrhage
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in 42 year old male
Reported by a physician from Thailand on 2012-05-30
Patient: 42 year old male
Reactions: Septic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in male
Reported by a physician from Thailand on 2012-05-29
Patient: male
Reactions: Septic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in 18 year old female
Reported by a physician from Thailand on 2012-05-16
Patient: 18 year old female
Reactions: Leukaemia Recurrent
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Noxafil
Other drugs received by patient: Bactrim
Possible Noxafil side effects in 43 year old male
Reported by a physician from Thailand on 2012-05-15
Patient: 43 year old male
Reactions: Haemorrhage
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in male
Reported by a physician from Thailand on 2012-05-15
Patient: male
Reactions: Septic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
Possible Noxafil side effects in 42 year old male
Reported by a physician from Thailand on 2012-05-15
Patient: 42 year old male
Reactions: Septic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Noxafil
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