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Nipent (Pentostatin) - Dyspnoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Dyspnoea (4)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nipent (Pentostatin) where reactions include dyspnoea. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Nipent side effects in 54 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-05

Patient: 54 year old male, weighing 119.0 kg (261.8 pounds)

Reactions: Nasopharyngitis, Dyspnoea, Oropharyngeal Pain, Pyrexia, Cough

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Acyclovir Sodium
    Dosage: 100 mg mwf cycle 1, then 878 d1 cycle 2-6
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-03-14
    End date: 2011-08-02

Campath
    Dosage: 30 mg, tiw x 4 weeks, subcutaneous
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-10-31
    End date: 2011-11-25

Cytoxan
    Dosage: 1404 mg on d1 c1-6, wks 1, 5, 9, 13, 17 and 21, intravenous (not otherwise specified)
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-03-14
    End date: 2011-08-02

Nipent
    Dosage: 9.36 mg on day 1 c1-6, intravenous (not otherwise specified)
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-03-14
    End date: 2011-08-02

Other drugs received by patient: Bactrim DS; Acyclovir



Possible Nipent side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-17

Patient: 70 year old male, weighing 66.3 kg (145.9 pounds)

Reactions: Productive Cough, Rales, Pericardial Effusion, Cardiomegaly, Oedema Peripheral, Pneumothorax, Cardiac Failure Congestive, Bronchopulmonary Aspergillosis, Pulmonary Necrosis, Cytomegalovirus Test Positive, Anaemia, Hypotension, Pancytopenia, Rhonchi, Dehydration, non-Small Cell Lung Cancer, Atelectasis, Confusional State, Nuchal Rigidity, Fall, Fatigue, Pleural Effusion, Musculoskeletal Stiffness, Sinusitis, Thrombocytopenia, Lethargy, Candidiasis, Decreased Appetite, Dyspnoea, Lung Neoplasm, Jugular Vein Distension, Cerebral Atrophy, Ascites, Hypophagia, Bradycardia, Bronchitis, Gait Disturbance, Asthenia, Blood Pressure Fluctuation, Face Injury

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Alemtuzumab
    Dosage: 60 mg, not reported
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-10-31
    End date: 2011-11-02

Cyclophosphamide
    Dosage: 1212mg, not reported
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

Nipent
    Dosage: 8 mg, not reported
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

Rituximab
    Dosage: 758 mg, not reported
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18



Possible Nipent side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-12

Patient: 70 year old male, weighing 61.0 kg (134.3 pounds)

Reactions: Confusional State, Atelectasis, Lung Infection, Nuchal Rigidity, Fall, Cardiomegaly, Pericardial Effusion, Fatigue, Oedema Peripheral, Musculoskeletal Stiffness, Pleural Effusion, Thrombocytopenia, Candidiasis, Lethargy, Cardiac Failure Congestive, Dyspnoea, Cytomegalovirus Test Positive, Anaemia, Cerebral Atrophy, Pancytopenia, Ascites, Fungal Infection, Dehydration, non-Small Cell Lung Cancer, Bronchitis, Face Injury, Mobility Decreased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
(Alemtuzumab)
    Dosage: 60 mg,
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-10-31
    End date: 2011-11-02

(Rituximab)
    Dosage: 758 mg
    Indication: Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

Cyclophosphamide
    Dosage: 1212 mg,
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

Nipent
    Dosage: 8 mg,
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18



Possible Nipent side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-27

Patient: 70 year old male, weighing 67.9 kg (149.4 pounds)

Reactions: Dyspnoea, Anaemia, Muscular Weakness, Hypoaesthesia, Fall, Paraesthesia, Fatigue, Dehydration, Platelet Count Decreased, Cytomegalovirus Infection, Blood Pressure Decreased, Immobile, Infestation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
(Rituximab)
    Dosage: 758 mg, not reported
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

Campath
    Dosage: 30 mg, tiw x 18 weeks, subcutaneous
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2011-07-29
    End date: 2011-09-14

Cyclophosphamide
    Dosage: 1212 mg
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

Nipent
    Dosage: 8 mg
    Indication: Chronic Lymphocytic Leukaemia
    Start date: 2010-12-27
    End date: 2011-05-18

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