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Index of reports
> Death (538)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) death. The selected reports were submitted to the FDA during the sample period of about a year. Reports 1 - 30 of 538 Next >>
Possible Nexavar side effects in 35 year old male
Reported by a physician from Japan on 2012-08-27
Patient: 35 year old male, weighing 68.3 kg (150.3 pounds)
Reactions: Hepatic Function Abnormal
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg (daily dose), , oral
Administration route: Oral
Start date: 2010-06-18
End date: 2010-06-19
Nexavar
Dosage: 400 mg (daily dose), , oral
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-06-11
End date: 2010-06-17
Other drugs received by patient: Fentanyl-100; Oxycontin; Restamin; Primperan TAB; Omeprazole; Magmitt; Enteronon R; Cefazolin Sodium; Ketoprofen; Celecoxib; Pursennid; Zometa; Baraclude; Prochlorperazine; Acetaminophen; Wystal; Enteronon R; Oxycodone Hydrochloride; Primperan TAB; Primperan TAB
Possible Nexavar side effects in male
Reported by a physician from United States on 2012-08-27
Patient: male
Reactions: Death, Adverse Drug Reaction, Toxicity To Various Agents
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 73 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-24
Patient: 73 year old female, weighing 48.0 kg (105.6 pounds)
Reactions: Hyperbilirubinaemia, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, General Physical Health Deterioration, Encephalopathy, Dizziness, Hypertension, Decreased Appetite
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-01-08
End date: 2010-01-10
Nexavar
Dosage: 800 mg, qd
Administration route: Oral
Start date: 2010-01-13
End date: 2010-01-19
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Start date: 2010-01-20
End date: 2010-03-02
Other drugs received by patient: Aldactone; Shakuyakukanzoutou; Omeprazole; Urso 250; Medicon; Allegra; Acetaminophen; Onealfa
Possible Nexavar side effects in 78 year old female
Reported by a physician from Czech Republic on 2012-08-24
Patient: 78 year old female, weighing 58.0 kg (127.6 pounds)
Reactions: Cardiac Failure, Malnutrition
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400mg daily
Administration route: Oral
Start date: 2010-06-03
End date: 2010-06-17
Nexavar
Dosage: 800mg daily
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-04-20
End date: 2010-06-02
Other drugs received by patient: Enalapril Maleate; Furosemide; Spironolactone; Furosemidum; Furosemidum
Possible Nexavar side effects in 58 year old female
Reported by a consumer/non-health professional from United States on 2012-08-24
Patient: 58 year old female, weighing 89.5 kg (197.0 pounds)
Reactions: Migraine, Respiratory Failure, Mitral Valve Incompetence
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-03-11
End date: 2010-04-08
Nexavar
Dosage: cycle 8 - as used dose: 400-200 mg
Administration route: Oral
Start date: 2010-08-03
End date: 2010-08-05
Nexavar
Dosage: cycle 10-due to subject error
Administration route: Oral
Start date: 2010-09-19
End date: 2010-09-20
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-01-15
End date: 2010-02-08
Nexavar
Dosage: cycle 10 - as used does: 400-200 mg
Administration route: Oral
Start date: 2010-09-21
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Thyroid Cancer Metastatic
Start date: 2009-12-17
End date: 2010-01-15
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-02-08
End date: 2010-03-11
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-04-08
End date: 2010-04-13
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-05-21
End date: 2010-06-23
Nexavar
Dosage: cycle 9 - as used dose: 400-200 mg
Administration route: Oral
Start date: 2010-08-05
End date: 2010-09-01
Nexavar
Dosage: cycle 12 : 400+200 mg qd
Administration route: Oral
Start date: 2010-09-23
End date: 2010-11-26
Other drugs received by patient: Synthroid; Lisinopril; Trazodone Hydrochloride; Pristiq; Ativan; Vitamin D; Lomotil [diphenoxylate Hydrochloride]; Dilaudid; Ambien; Hyzaar; Prednisone TAB; Valium; Sodium Chloride; Lorazepam; Calcium Carbonate; Procardia XL; Fiorinal W / Codeine; Fioricet W / Codeine; Procardia XL; Sodium Chloride
Possible Nexavar side effects in 55 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23
Patient: 55 year old male
Reactions: Jaundice, Abdominal Pain, Hyperkalaemia, Chills, Mental Status Changes, Pyrexia, Loss of Consciousness, Death, Hepatic Encephalopathy, Fatigue, Cholangitis, Pleural Effusion, Thrombocytopenia, Renal Failure Acute, Nausea, Malnutrition, Urinary Tract Infection, Anaemia, Hyponatraemia, Rash, Bacteraemia, Dehydration, Ammonia Increased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, bid
Indication: Hepatic Neoplasm Malignant
Start date: 2012-05-25
End date: 2012-06-05
Nexavar
Dosage: 400 mg, bid
Start date: 2012-06-01
Other drugs received by patient: Lorazepam; Diphenoxylate HCL and Atropine Sulfate; Lortab; Lasix; Albuterol; Aldactone; Protonix
Possible Nexavar side effects in 59 year old male
Reported by a physician from France on 2012-08-23
Patient: 59 year old male, weighing 120.0 kg (264.0 pounds)
Reactions: Fatigue, Hepatic Neoplasm Malignant, Hepatic Failure, Encephalopathy, Hepatic Cirrhosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Propranolol; Glucophage; Lorazepam
Possible Nexavar side effects in 58 year old female
Reported by a physician from Korea, Republic of on 2012-08-22
Patient: 58 year old female, weighing 37.0 kg (81.4 pounds)
Reactions: Fanconi Syndrome, Lung Infection
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Capecitabine
Dosage: 2900 mg, qd
Indication: Gastric Cancer
Start date: 2012-03-08
End date: 2012-03-22
Capecitabine
Dosage: 2900 mg, qd
Start date: 2012-03-28
End date: 2012-04-09
Cisplatin
Dosage: 118 mg
Start date: 2012-03-28
End date: 2012-03-28
Cisplatin
Dosage: 118 mg
Indication: Gastric Cancer
Start date: 2012-03-08
End date: 2012-03-08
Nexavar
Dosage: 400 mg, bid
Indication: Gastric Cancer
Start date: 2012-06-30
End date: 2012-07-14
Other drugs received by patient: Enoxaparin; Levofloxacin; Nystatin; Nystatin; Enoxaparin; Enoxaparin; Piperacillin / Tazobactam; Bromhexin; Ceftriaxone; Ambroxol; Meropenem; Moxifloxacin; Azithromycin; Ceftriaxone; Acetylcysteine; Azithromycin
Possible Nexavar side effects in 73 year old male
Reported by a physician from Japan on 2012-08-20
Patient: 73 year old male, weighing 52.0 kg (114.4 pounds)
Reactions: Malaise, Hepatic Neoplasm Malignant, Diarrhoea, Pyrexia, Altered State of Consciousness
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 69 year old male
Reported by a physician from Japan on 2012-08-17
Patient: 69 year old male
Reactions: Liver Abscess, Septic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Baraclude
Dosage: 0.5 mg, qd
Administration route: Oral
Indication: Hepatitis B
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-05-11
End date: 2012-06-26
Possible Nexavar side effects in 53 year old male
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 53 year old male
Reactions: Confusional State, Agitation, Dysphagia, Pain, Anaemia, Failure To Thrive, Hypokalaemia, Death, Fatigue, Fluid Intake Reduced, Asthenia, Decreased Appetite, Deep Vein Thrombosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg am, 200 mg pm x 21days
Indication: Colorectal Cancer Metastatic
Start date: 2012-06-22
End date: 2012-08-07
Xeloda
Dosage: 1500 mg am, 1650 mg pm x 14 days
Indication: Colorectal Cancer Metastatic
Start date: 2012-06-22
End date: 2012-08-01
Other drugs received by patient: Roxicodone; Compazine; Ferrous Fumarate; MS Contin; Phenergan HCL; Prinzide; Multi-Vitamin; Compazine
Possible Nexavar side effects in 58 year old female
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 58 year old female, weighing 89.5 kg (197.0 pounds)
Reactions: Migraine, Respiratory Failure, Mitral Valve Incompetence
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-02-08
End date: 2010-03-11
Nexavar
Dosage: cycle 10-due to subject error
Administration route: Oral
Start date: 2010-09-19
End date: 2010-09-20
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-04-08
End date: 2010-04-13
Nexavar
Dosage: cycle 12 : 400+200 mg qd
Administration route: Oral
Start date: 2010-09-23
End date: 2010-11-26
Nexavar
Dosage: cycle 8 - as used dose: 400-200 mg
Administration route: Oral
Start date: 2010-08-03
End date: 2010-08-05
Nexavar
Dosage: cycle 10 - as used does: 400-200 mg
Administration route: Oral
Start date: 2010-09-21
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Thyroid Cancer Metastatic
Start date: 2009-12-17
End date: 2010-01-15
Nexavar
Dosage: cycle 9 - as used dose: 400-200 mg
Administration route: Oral
Start date: 2010-08-05
End date: 2010-09-01
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-03-11
End date: 2010-04-08
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-05-21
End date: 2010-06-23
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2010-01-15
End date: 2010-02-08
Other drugs received by patient: Synthroid; Dilaudid; Lisinopril; Lorazepam; Lomotil [diphenoxylate Hydrochloride]; Pristiq; Procardia XL; Valium; Sodium Chloride; Sodium Chloride; Ativan; Hyzaar; Prednisone TAB; Fioricet W / Codeine; Procardia XL; Calcium Carbonate; Trazodone Hydrochloride; Fiorinal W / Codeine; Ambien; Vitamin D
Possible Nexavar side effects in 54 year old male
Reported by a physician from Japan on 2012-08-13
Patient: 54 year old male, weighing 40.5 kg (89.1 pounds)
Reactions: Blood Bilirubin Increased, Blood Alkaline Phosphatase Increased, Pneumonia, Hepatic Function Abnormal, Anaemia, Constipation, Ascites, Diarrhoea, Platelet Count Decreased, Metastases To Bone, Liver Carcinoma Ruptured, Bilirubin Conjugated Increased, Decreased Appetite
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-10
End date: 2009-09-10
Nexavar
Dosage: 600 mg, qd
Administration route: Oral
Start date: 2009-09-12
End date: 2009-09-25
Other drugs received by patient: Fentanyl-100; TPN; Zolpidem; Bismuth Subnitrate; Voltaren; Lansoprazole; Albumin Tannate; Oxycodone Hydrochloride; Elemenmic
Possible Nexavar side effects in 64 year old male
Reported by a physician from Italy on 2012-08-10
Patient: 64 year old male, weighing 90.0 kg (198.0 pounds)
Reactions: Hepatic Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 56 year old male
Reported by a physician from United States on 2012-08-10
Patient: 56 year old male
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 64 year old male
Reported by a pharmacist from Japan on 2012-08-09
Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Diarrhoea, Hepatic Neoplasm Malignant, Hyperammonaemia, Eczema, Decreased Appetite, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-09-09
End date: 2009-10-01
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-10-28
End date: 2009-10-30
Nexavar
Dosage: 600 mg/day
Administration route: Oral
Start date: 2009-10-02
End date: 2009-10-27
Nexavar
Dosage: 800 mg/day
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-06
End date: 2009-09-08
Other drugs received by patient: Lamivudine; Mucosta; Aldactone; Lasix; Oxycontin; Rabeprazole Sodium; Loxoprofen; Fentanyl-100; Pastaron; Ensure [minerals Nos,vitamins Nos]; Hepsera; Hypoca; Morphine; Aldactone
Possible Nexavar side effects in 68 year old female
Reported by a physician from Japan on 2012-08-09
Patient: 68 year old female, weighing 49.0 kg (107.8 pounds)
Reactions: Hepatic Neoplasm Malignant, Disseminated Intravascular Coagulation, Sepsis, Duodenal Ulcer, Melaena, Haemorrhagic Ascites
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Diclofenac Sodium
Dosage: 25 mg, unk
Indication: Product Used FOR Unknown Indication
Start date: 2009-06-22
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-06-16
End date: 2009-06-23
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2009-06-24
End date: 2009-06-28
Other drugs received by patient: Aldactone; Lasix; Fentanyl-100
Possible Nexavar side effects in 59 year old female
Reported by a physician from Korea, Republic of on 2012-08-09
Patient: 59 year old female, weighing 48.0 kg (105.6 pounds)
Reactions: Fanconi Syndrome, Lung Infection
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Capecitabine
Cisplatin
Nexavar
Dosage: 400 mg, bid
Indication: Gastric Cancer
Start date: 2012-06-30
End date: 2012-07-14
Possible Nexavar side effects in 65 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 65 year old male, weighing 73.0 kg (160.6 pounds)
Reactions: Hepatic Failure, Liver Disorder
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, daily
Administration route: Oral
Start date: 2012-04-12
End date: 2012-05-15
Nexavar
Dosage: 800 mg,daily
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-03-06
End date: 2012-04-11
Other drugs received by patient: Claritin; Lasix; Spironolactone; Livact
Possible Nexavar side effects in 67 year old female
Reported by a physician from Japan on 2012-08-08
Patient: 67 year old female
Reactions: Hepatic Failure, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 62 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 62 year old male, weighing 57.0 kg (125.4 pounds)
Reactions: Fatigue, Dyspnoea, Diarrhoea, Bone Marrow Failure, Acute Respiratory Distress Syndrome, Decreased Appetite
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 800 mg
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-03-10
End date: 2012-03-20
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2012-04-01
End date: 2012-05-01
Nexavar
Dosage: 400 mg, qod
Start date: 2012-04-28
End date: 2012-04-30
Nexavar
Dosage: 200 mg, bid
Start date: 2012-03-29
End date: 2012-04-27
Other drugs received by patient: Silece; Risperidone; Zometa; Fentanyl Citrate; Lyrica; Loxonin; Lamivudine; Hepsera
Possible Nexavar side effects in 48 year old male
Reported by a physician from Taiwan, Province of China on 2012-08-08
Patient: 48 year old male, weighing 67.7 kg (148.9 pounds)
Reactions: Hepatic Function Abnormal, Sepsis, Hepatic Failure, Constipation, Acute Respiratory Failure, Oesophageal Varices Haemorrhage
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-10-05
End date: 2011-10-25
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Start date: 2011-11-15
End date: 2011-11-15
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2011-10-26
End date: 2011-11-14
Other drugs received by patient: Entecavir; Lactulose; Metoclopramide; Ultracet; Oxybutynin Chloride; Tamsulosin HCL; Esomeprazole
Possible Nexavar side effects in 74 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 74 year old male
Reactions: Intra-Abdominal Haemorrhage, Haematemesis, Loss of Consciousness, Upper Gastrointestinal Haemorrhage, Liver Carcinoma Ruptured, Melaena, Cardiac Arrest, Catheter Site Pain
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-10-29
End date: 2009-11-23
Nexavar
Dosage: 400 mg (daily dose), , oral
Administration route: Oral
Start date: 2009-11-24
End date: 2009-11-28
Other drugs received by patient: Novorapid; Novolin R; Norfloxacin; Tokisyakuyakusan; Magmitt; Lamivudine
Possible Nexavar side effects in 77 year old female
Reported by a physician from Japan on 2012-08-08
Patient: 77 year old female
Reactions: Abdominal Pain, Vomiting, Portal Venous GAS, Intestinal Haemorrhage, Malaise, Pneumatosis Intestinalis, Blood Creatinine Increased, Thrombocytopenia
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Indication: Renal Cell Carcinoma
Start date: 2011-05-23
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
End date: 2011-06-01
Possible Nexavar side effects in 59 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 59 year old male
Reactions: Hepatic Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 72 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 72 year old male
Reactions: Hepatic Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 72 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 72 year old male
Reactions: Hepatic Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 65 year old female
Reported by a physician from Australia on 2012-08-07
Patient: 65 year old female, weighing 79.8 kg (175.6 pounds)
Reactions: Influenza
Adverse event resulted in: death
Drug(s) suspected as cause:
Erlotinib Hydrochloride
Dosage: 50 mg, qd
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
End date: 2012-07-26
Erlotinib Hydrochloride
Dosage: 50 mg, qd
Administration route: Oral
Start date: 2012-07-30
Nexavar
Dosage: 400 mg, qod
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
End date: 2012-07-26
Nexavar
Dosage: unk
Start date: 2012-07-30
Other drugs received by patient: Valium; Amlodipine; Temazepam; Vitaminorum; Irbesartan; Thiamine HCL; Seretide MDI; Magnesium Aspartate Hydrochloride; Human Insulin; Motilium; Alendronate Sodium; Propranolol; Doxepin HCL; Lactulose
Possible Nexavar side effects in 59 year old male
Reported by a physician from United States on 2012-08-06
Patient: 59 year old male
Reactions: Death, Hepatic Neoplasm Malignant
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 55 year old male
Reported by a physician from Japan on 2012-08-06
Patient: 55 year old male
Reactions: Jaundice Cholestatic
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
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