Index of reports
> Cases with Hepatic Neoplasm Malignant (164)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include hepatic neoplasm malignant. The selected reports were submitted to the FDA during the sample period of about a year.
Reports 1 - 30 of 164 Next >>
Possible Nexavar side effects in 59 year old male
Reported by a physician from France on 2012-08-23
Patient: 59 year old male, weighing 120.0 kg (264.0 pounds)
Reactions: Fatigue, Hepatic Neoplasm Malignant, Hepatic Failure, Encephalopathy, Hepatic Cirrhosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Propranolol; Glucophage; Lorazepam
Possible Nexavar side effects in 69 year old female
Reported by a physician from Denmark on 2012-08-22
Patient: 69 year old female
Reactions: Hepatic Neoplasm Malignant, JAW Fracture, Loose Tooth, Dental Leakage
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 73 year old male
Reported by a physician from Japan on 2012-08-20
Patient: 73 year old male, weighing 52.0 kg (114.4 pounds)
Reactions: Malaise, Hepatic Neoplasm Malignant, Diarrhoea, Pyrexia, Altered State of Consciousness
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 61 year old male
Reported by a consumer/non-health professional from United States on 2012-08-14
Patient: 61 year old male
Reactions: Vomiting, Hepatic Neoplasm Malignant
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Indication: Hepatic Neoplasm Malignant
Start date: 2011-01-01
Nexavar
Dosage: 400 mg, bid
Nexavar
Dosage: 400 mg, bid
Nexavar
Dosage: 400 mg, bid
Nexavar
Dosage: 400 mg, bid
Nexavar
Dosage: unk
End date: 2012-03-23
Nexavar
Dosage: 400 mg, bid
Nexavar
Dosage: 400 mg, bid
Nexavar
Dosage: 400 mg, bid
Possible Nexavar side effects in 64 year old male
Reported by a pharmacist from Japan on 2012-08-09
Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Diarrhoea, Hepatic Neoplasm Malignant, Hyperammonaemia, Eczema, Decreased Appetite, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-09-09
End date: 2009-10-01
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-10-28
End date: 2009-10-30
Nexavar
Dosage: 600 mg/day
Administration route: Oral
Start date: 2009-10-02
End date: 2009-10-27
Nexavar
Dosage: 800 mg/day
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-06
End date: 2009-09-08
Other drugs received by patient: Lamivudine; Mucosta; Aldactone; Lasix; Oxycontin; Rabeprazole Sodium; Loxoprofen; Fentanyl-100; Pastaron; Ensure [minerals Nos,vitamins Nos]; Hepsera; Hypoca; Morphine; Aldactone
Possible Nexavar side effects in 68 year old female
Reported by a physician from Japan on 2012-08-09
Patient: 68 year old female, weighing 49.0 kg (107.8 pounds)
Reactions: Hepatic Neoplasm Malignant, Disseminated Intravascular Coagulation, Sepsis, Duodenal Ulcer, Melaena, Haemorrhagic Ascites
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Diclofenac Sodium
Dosage: 25 mg, unk
Indication: Product Used FOR Unknown Indication
Start date: 2009-06-22
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-06-16
End date: 2009-06-23
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2009-06-24
End date: 2009-06-28
Other drugs received by patient: Aldactone; Lasix; Fentanyl-100
Possible Nexavar side effects in 59 year old male
Reported by a physician from United States on 2012-08-06
Patient: 59 year old male
Reactions: Death, Hepatic Neoplasm Malignant
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 81 year old male
Reported by a physician from Japan on 2012-08-06
Patient: 81 year old male, weighing 45.8 kg (100.8 pounds)
Reactions: Neutrophil Count Increased, Hepatic Function Abnormal, Amylase Increased, Hepatic Neoplasm Malignant, Disseminated Intravascular Coagulation, Anaemia, Hyponatraemia, Pyrexia, Cardiac Failure Acute, Ascites, Platelet Count Decreased, Ammonia Increased, Lipase Increased
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-06-10
End date: 2010-06-22
Nexavar
Dosage: 400 mg, qod
Administration route: Oral
Start date: 2010-06-24
End date: 2010-06-25
Other drugs received by patient: Magmitt; Antianaemic Preparations; Pantosin; Metilon; Aminoleban; Urso 250; Losartan Potassium; Metilon; Urepearl; Metilon; Metilon; Ferrous Sulfate TAB; Hirudoid; Metilon; Metilon
Possible Nexavar side effects in 73 year old female
Reported by a physician from Japan on 2012-08-02
Patient: 73 year old female
Reactions: Hepatic Neoplasm Malignant, Palmar-Plantar Erythrodysaesthesia Syndrome, Jaundice Cholestatic, Duodenal Stenosis, Liver Disorder
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg - dose reduced
Start date: 2012-01-01
End date: 2012-01-01
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-09-09
Other drugs received by patient: Warfarin Potassium
Possible Nexavar side effects in 72 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-30
Patient: 72 year old female
Reactions: Hepatic Neoplasm Malignant
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Oxycodone HCL; Zolpidem; Glimepiride; Spironolactone; Ranitidine; Omeprazole; Cetirizine HCL; Singulair; Torsemide; Calcium D; Qvar 40; Metaxalone; Acebutolol; Januvia; Amlodipine; Prochlorperaz
Possible Nexavar side effects in 86 year old male
Reported by a physician from Japan on 2012-07-26
Patient: 86 year old male, weighing 42.0 kg (92.4 pounds)
Reactions: Hepatic Neoplasm Malignant, Neoplasm Progression, Liver Disorder
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Lasix; Taurine; Famotidine; Urso 250; Aldactone
Possible Nexavar side effects in 67 year old female
Reported by a physician from United States on 2012-07-24
Patient: 67 year old female, weighing 64.5 kg (141.9 pounds)
Reactions: Renal Failure, Vomiting, Hepatic Neoplasm Malignant, Nausea
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 54 year old female
Reported by a consumer/non-health professional from China on 2012-07-24
Patient: 54 year old female
Reactions: Hepatic Neoplasm Malignant, Tumour Haemorrhage, Haematemesis, Abdominal Pain Upper
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 65 year old female
Reported by a consumer/non-health professional from United States on 2012-07-24
Patient: 65 year old female, weighing 70.2 kg (154.4 pounds)
Reactions: Hepatic Neoplasm Malignant, Pulmonary Oedema
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Indication: Metastatic Neoplasm
Start date: 2012-04-03
Nexavar
Indication: Metastases To Liver
Other drugs received by patient: Oxycontin; Compazine; Dulcolax [docusate Sodium]; Oxycodone HCL; Senna-Mint WAF; Amlodipine Besylate and Benazepril HCL; Vicodin
Possible Nexavar side effects in 75 year old male
Reported by a physician from Japan on 2012-07-24
Patient: 75 year old male, weighing 53.2 kg (117.0 pounds)
Reactions: Fatigue, Vomiting, Stomatitis, Ileus, Nausea, Hepatic Neoplasm Malignant, Palmar-Plantar Erythrodysaesthesia Syndrome, Decreased Appetite
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 800 mg (daily dose), , oral
Administration route: Oral
Start date: 2009-08-03
End date: 2009-08-18
Nexavar
Dosage: 800 mg (daily dose), , oral
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-07-30
End date: 2009-07-31
Oxycontin
Dosage: since before nexavar administration
Administration route: Oral
Indication: Pain Management
End date: 2009-08-17
Oxycontin
Dosage: 160 mg (daily dose), , unknown
Start date: 2009-08-18
End date: 2009-08-23
Other drugs received by patient: Sennoside; Sepamit; Gabapentin; Amitriptyline HCL; Keratinamin; Voltaren; Omeprazole; Maglax; Fentanyl-100; Mucosta; Loxonin; Fentanyl-100; Oxycodone Hydrochloride; Anpec
Possible Nexavar side effects in 62 year old female
Reported by a physician from Japan on 2012-07-20
Patient: 62 year old female, weighing 58.0 kg (127.6 pounds)
Reactions: Hepatic Function Abnormal, Hepatic Neoplasm Malignant, Nausea, Diarrhoea
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-01-18
End date: 2012-01-25
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
Start date: 2012-01-25
End date: 2012-01-29
Possible Nexavar side effects in 58 year old male
Reported by a physician from Japan on 2012-07-20
Patient: 58 year old male, weighing 60.0 kg (132.0 pounds)
Reactions: Hepatic Neoplasm Malignant, Duodenal Ulcer Haemorrhage, Faeces Discoloured
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400mg daily
Administration route: Oral
Start date: 2011-06-06
End date: 2011-06-30
Nexavar
Dosage: 200 mg daily
Administration route: Oral
Start date: 2011-05-25
End date: 2011-06-05
Nexavar
Dosage: 800 mg daily
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-03-28
End date: 2011-05-20
Other drugs received by patient: Diovan; Tamsulosin HCL; Carvedilol; Baraclude; Omeprazole; Urso 250; Daikentyuto; Rabeprazole Sodium
Possible Nexavar side effects in 74 year old female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-19
Patient: 74 year old female
Reactions: Abdominal Pain, Weight Decreased, Hepatic Neoplasm Malignant, Portal Vein Thrombosis, Musculoskeletal Pain, Pyrexia, Headache, Ascites, Hepatic Enzyme Increased, Diarrhoea, Asthenia, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 67 year old female
Reported by a physician from Japan on 2012-07-18
Patient: 67 year old female
Reactions: White Blood Cell Count Decreased, Pneumonia, Hepatic Neoplasm Malignant, Platelet Count Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 800 mg
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-04-27
End date: 2012-05-23
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
End date: 2012-05-24
Possible Nexavar side effects in 66 year old male
Reported by a physician from Japan on 2012-07-17
Patient: 66 year old male, weighing 70.0 kg (154.0 pounds)
Reactions: Hepatic Encephalopathy, Hepatic Neoplasm Malignant, Bradykinesia, Depressed Level of Consciousness, Asthenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Adalat; Glimicron
Possible Nexavar side effects in 65 year old male
Reported by a physician from Japan on 2012-07-17
Patient: 65 year old male, weighing 53.4 kg (117.5 pounds)
Reactions: Hepatic Function Abnormal, Hepatic Neoplasm Malignant, Hepatic Failure, Neoplasm Progression, Rash, Oesophageal Varices Haemorrhage, Haematemesis, Renal Failure, Interstitial Lung Disease, Diarrhoea
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 600 mg (daily dose), , oral
Administration route: Oral
Start date: 2009-07-22
End date: 2009-07-30
Nexavar
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-06-29
End date: 2009-07-21
Other drugs received by patient: Proheparum; Monilac; Rabeprazole Sodium; Glycyron [glycyrrhizic Acid]; FOY; Rhythmy; Aldactone; Etodolac; Flomax; Urso 250; Loxonin
Possible Nexavar side effects in 59 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-10
Patient: 59 year old male, weighing 115.0 kg (253.0 pounds)
Reactions: Hepatic Neoplasm Malignant, Cerebral Ischaemia, Convulsion
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Lidocaine; Hydralazine Hydrochloride; Norvasc; Aspirin; Omeprazole; Norvasc; Rapamune; Morphine; Percocet; Percocet; Acyclovir; Acetaminophen; Rapamune; Polyethylene Glycol; Sulfamethoxazole and Trimethoprim; Rapamune; Aspirin; Hydralazine Hydrochloride; Oxycontin; Lidocaine; Magnesium Oxide
Possible Nexavar side effects in 74 year old male
Reported by a physician from Japan on 2012-07-06
Patient: 74 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Hepatic Neoplasm Malignant, Hyperkalaemia, Disseminated Intravascular Coagulation, International Normalised Ratio Increased, Pyrexia, Hypernatraemia, Diarrhoea, Sepsis, Metastases To Central Nervous System, Decreased Appetite
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Digoxin; Lasix; Oxycontin; Magnesium Oxide; Motilium; Warfarin Sodium; Alosenn; Aldactone; Oxycodone Hydrochloride; Oxycodone Hydrochloride; Polaramine; Prochlorperazine; Lansoprazole
Possible Nexavar side effects in 65 year old male
Reported by a physician from Japan on 2012-07-05
Patient: 65 year old male
Reactions: Nausea, Hepatic Neoplasm Malignant, Hepatic Artery Occlusion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2011-02-15
End date: 2011-05-09
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-12-02
Nexavar
Dosage: daily dose 800 mg
Administration route: Oral
Start date: 2011-01-01
Other drugs received by patient: Chemotherapeutics NOS; Combinations OF Antineoplastic Agents; Fluorouracil; Cisplatin
Possible Nexavar side effects in 68 year old female
Reported by a physician from Japan on 2012-07-05
Patient: 68 year old female, weighing 49.0 kg (107.8 pounds)
Reactions: Hepatic Neoplasm Malignant, Disseminated Intravascular Coagulation, Sepsis, Palmar-Plantar Erythrodysaesthesia Syndrome, Duodenal Ulcer, Haemorrhagic Ascites, Melaena
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Diclofenac Sodium
Dosage: 25 mg, unk
Indication: Product Used FOR Unknown Indication
Start date: 2009-06-22
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2009-06-24
End date: 2009-06-28
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-06-16
End date: 2009-06-23
Other drugs received by patient: Lasix; Aldactone; Fentanyl-100
Possible Nexavar side effects in 62 year old female
Reported by a physician from Japan on 2012-07-05
Patient: 62 year old female, weighing 58.0 kg (127.6 pounds)
Reactions: Hepatic Function Abnormal, Nausea, Hepatic Neoplasm Malignant, Diarrhoea
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
Start date: 2012-01-25
End date: 2012-01-29
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-01-18
End date: 2012-01-25
Possible Nexavar side effects in 64 year old male
Reported by a pharmacist from Japan on 2012-07-02
Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Hepatic Neoplasm Malignant, Diarrhoea, Hyperammonaemia, Palmar-Plantar Erythrodysaesthesia Syndrome, Eczema, Decreased Appetite, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 800 mg/day
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-06
End date: 2009-09-08
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-10-28
End date: 2009-10-30
Nexavar
Dosage: 600 mg/day
Administration route: Oral
Start date: 2009-10-02
End date: 2009-10-27
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-09-09
End date: 2009-10-01
Other drugs received by patient: Pastaron; Morphine; Fentanyl-100; Aldactone; Rabeprazole Sodium; Mucosta; Ensure [minerals Nos,vitamins Nos]; Hypoca; Aldactone; Lamivudine; Oxycontin; Hepsera; Loxoprofen; Lasix
Possible Nexavar side effects in 78 year old male
Reported by a physician from Japan on 2012-07-02
Patient: 78 year old male, weighing 53.0 kg (116.6 pounds)
Reactions: Hepatic Function Abnormal, Hepatic Neoplasm Malignant, Platelet Count Decreased
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg daily
Administration route: Oral
Start date: 2011-03-25
End date: 2011-04-21
Nexavar
Dosage: 400 mg, qod
Start date: 2011-04-21
End date: 2011-07-29
Other drugs received by patient: Urso 250; Livact; Lansoprazole
Possible Nexavar side effects in 60 year old female
Reported by a consumer/non-health professional from United States on 2012-06-29
Patient: 60 year old female
Reactions: Hepatic Neoplasm Malignant
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Ondansetron; Lorazepam; Nexium; Rapamune; Lamictal
Possible Nexavar side effects in 73 year old male
Reported by a physician from United States on 2012-06-29
Patient: 73 year old male
Reactions: Hospitalisation, Hepatic Neoplasm Malignant, Hepatic Failure, Pyrexia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
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