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Index of reports
> Cases with Diarrhoea (345)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include diarrhoea. The selected reports were submitted to the FDA during the sample period of about a year. Reports 1 - 30 of 345 Next >>
Possible Nexavar side effects in 62 year old male
Reported by a physician from Japan on 2012-08-27
Patient: 62 year old male
Reactions: Diarrhoea, Cerebral Infarction, Palmar-Plantar Erythrodysaesthesia Syndrome
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-06-21
End date: 2010-10-11
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Start date: 2010-10-12
End date: 2010-11-19
Possible Nexavar side effects in 59 year old female
Reported by a physician from United States on 2012-08-27
Patient: 59 year old female, weighing 59.0 kg (129.7 pounds)
Reactions: Weight Decreased, Peripheral Coldness, Vomiting, Glossodynia, Nausea, Pain, Rash, Hyperhidrosis, Constipation, Erythema, Fatigue, Diarrhoea, Dehydration, Feeling Hot, Dizziness, Cold Sweat, Blister
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, daily
Administration route: Oral
Start date: 2012-07-14
Nexavar
Dosage: 400 mg, qd
Indication: Hepatic Neoplasm Malignant
Start date: 2012-05-09
Nexavar
Dosage: 400 mg, bid
Start date: 2012-05-19
Nexavar
Dosage: 400 mg am and 200 mg pm
End date: 2012-07-11
Possible Nexavar side effects in 54 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27
Patient: 54 year old male
Reactions: Blood Pressure Increased, Weight Decreased, Nausea, Pain in Extremity, Hypotension, Rash, Skin Irritation, Frequent Bowel Movements, Fatigue, Diarrhoea, Gait Disturbance, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 67 year old male
Reported by a physician from Korea, Republic of on 2012-08-24
Patient: 67 year old male, weighing 63.0 kg (138.6 pounds)
Reactions: Diarrhoea, Febrile Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 800 mg
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-03-09
End date: 2011-04-13
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2011-04-14
End date: 2011-08-26
Possible Nexavar side effects in 65 year old male
Reported by a physician from Japan on 2012-08-24
Patient: 65 year old male, weighing 63.0 kg (138.6 pounds)
Reactions: C-Reactive Protein Increased, Diarrhoea, Aspartate Aminotransferase Increased, Pyrexia, Rash
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-05-15
End date: 2012-07-27
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2012-08-03
Other drugs received by patient: Loxonin; Lendormin; Livact; Allopurinol; Amlodipine; Micardis; Pravastatin Sodium; Urso 250; Lansoprazole; Pursennid; Doxazosin Mesylate; Enalapril Maleate
Possible Nexavar side effects in 63 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-21
Patient: 63 year old female, weighing 48.1 kg (105.8 pounds)
Reactions: Blood Creatine Phosphokinase Increased, Angina Unstable, Palmar-Plantar Erythrodysaesthesia Syndrome, Wound Infection, Blood Creatine Phosphokinase MB Increased, Malaise, C-Reactive Protein Increased, Diarrhoea, Impaired Healing, Hepatectomy, Chest Pain, Platelet Count Decreased, Skin Necrosis, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-01-07
End date: 2011-01-28
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Indication: Metastases To Lung
Start date: 2011-03-05
End date: 2011-03-24
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Start date: 2011-03-17
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-04-22
End date: 2011-08-22
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-10-25
End date: 2011-10-30
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-08-31
End date: 2011-10-23
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-11-03
Other drugs received by patient: Urepearl; Epirubicin Hydrochloride; Famotidine; Amlodipine; Miriplatin
Possible Nexavar side effects in 67 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20
Patient: 67 year old female
Reactions: Adverse Drug Reaction, Oropharyngeal Pain, Constipation, Pharyngeal Oedema, Hair Texture Abnormal, Oedema Peripheral, DRY Mouth, Blister, LIP DRY, Pain in Extremity, Palmar-Plantar Erythrodysaesthesia Syndrome, Ear Infection, Antibiotic Therapy, Arthralgia, Diarrhoea, Limb Injury, Joint Swelling, Alopecia, Hair Disorder
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Indication: Thyroid Cancer
Start date: 2009-07-09
Nexavar
Dosage: 200 mg, qd
Administration route: Oral
Nexavar
Dosage: 200 mg, qd
Administration route: Oral
Nexavar
Dosage: 200 mg, qd
Administration route: Oral
Nexavar
Dosage: 200 mg, qd
Administration route: Oral
Nexavar
Dosage: 200 mg, qd
Administration route: Oral
Nexavar
Possible Nexavar side effects in 73 year old male
Reported by a physician from Japan on 2012-08-20
Patient: 73 year old male, weighing 52.0 kg (114.4 pounds)
Reactions: Malaise, Hepatic Neoplasm Malignant, Diarrhoea, Pyrexia, Altered State of Consciousness
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 65 year old male
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 65 year old male
Reactions: Tumour Necrosis, Vomiting, Nausea, Musculoskeletal Pain, Pain, Neoplasm Progression, Pyrexia, Weight Increased, Diarrhoea, Nail Disorder
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 63 year old male
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-08-17
Patient: 63 year old male, weighing 67.0 kg (147.4 pounds)
Reactions: Weight Decreased, Blood Pressure Increased, Abdominal Pain, Back Pain, Urinary Tract Infection, Diplopia, Diarrhoea, Metastases To Bone, Eye Disorder, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Preparations Increasing Uric Acid Excretion; Omeprazole; Captopril; Hydrochlorothiazide; Preparations Increasing Uric Acid Excretion; Preparations Increasing Uric Acid Excretion; Preparations Increasing Uric Acid Excretion; Hydrochlorothiazide
Possible Nexavar side effects in 54 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 54 year old male
Reactions: Frequent Bowel Movements, Diarrhoea, Pain in Extremity, Rash, Gait Disturbance, Skin Irritation
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 60 year old male
Reported by a physician from United States on 2012-08-15
Patient: 60 year old male
Reactions: Weight Decreased, Cellulitis, Retching, Pain in Extremity, Pyrexia, Fall, Erythema, Diarrhoea, Oedema Peripheral, Asthenia, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Analgesics
Possible Nexavar side effects in 79 year old female
Reported by a physician from Japan on 2012-08-14
Patient: 79 year old female, weighing 54.4 kg (119.7 pounds)
Reactions: Abdominal Pain, Vomiting, Nausea, Diarrhoea, Abdominal Distension, Subileus
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Urso 250; Rabeprazole Sodium; Alcadol; Lorazepam; Dogmatyl; Livact; Alendronate Sodium; Trichlormethiazide
Possible Nexavar side effects in 54 year old male
Reported by a physician from Japan on 2012-08-13
Patient: 54 year old male, weighing 40.5 kg (89.1 pounds)
Reactions: Blood Bilirubin Increased, Blood Alkaline Phosphatase Increased, Pneumonia, Hepatic Function Abnormal, Anaemia, Constipation, Ascites, Diarrhoea, Platelet Count Decreased, Metastases To Bone, Liver Carcinoma Ruptured, Bilirubin Conjugated Increased, Decreased Appetite
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-10
End date: 2009-09-10
Nexavar
Dosage: 600 mg, qd
Administration route: Oral
Start date: 2009-09-12
End date: 2009-09-25
Other drugs received by patient: Fentanyl-100; TPN; Zolpidem; Bismuth Subnitrate; Voltaren; Lansoprazole; Albumin Tannate; Oxycodone Hydrochloride; Elemenmic
Possible Nexavar side effects in 59 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10
Patient: 59 year old female
Reactions: Weight Decreased, Peripheral Coldness, Glossodynia, Pain, Constipation, Erythema, Hyperhidrosis, Fatigue, Feeling Hot, Dizziness, Cold Sweat, Blister, Vomiting, Nausea, Rash, Diarrhoea, Dehydration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Start date: 2012-05-19
Nexavar
Dosage: 400 mg am and 200 mg pm
End date: 2012-07-11
Nexavar
Dosage: 400 mg, daily
Administration route: Oral
Start date: 2012-07-14
Nexavar
Dosage: 400 mg, qd
Indication: Hepatic Neoplasm Malignant
Start date: 2012-05-09
Possible Nexavar side effects in 64 year old male
Reported by a pharmacist from Japan on 2012-08-09
Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Diarrhoea, Hepatic Neoplasm Malignant, Hyperammonaemia, Eczema, Decreased Appetite, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-09-09
End date: 2009-10-01
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-10-28
End date: 2009-10-30
Nexavar
Dosage: 600 mg/day
Administration route: Oral
Start date: 2009-10-02
End date: 2009-10-27
Nexavar
Dosage: 800 mg/day
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-06
End date: 2009-09-08
Other drugs received by patient: Lamivudine; Mucosta; Aldactone; Lasix; Oxycontin; Rabeprazole Sodium; Loxoprofen; Fentanyl-100; Pastaron; Ensure [minerals Nos,vitamins Nos]; Hepsera; Hypoca; Morphine; Aldactone
Possible Nexavar side effects in 79 year old female
Reported by a physician from Japan on 2012-08-09
Patient: 79 year old female
Reactions: Diarrhoea, Abdominal Distension
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 54 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-08
Patient: 54 year old male
Reactions: Frequent Bowel Movements, Diarrhoea, Pain in Extremity, Gait Disturbance, Rash, Skin Irritation
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 62 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 62 year old male, weighing 57.0 kg (125.4 pounds)
Reactions: Fatigue, Dyspnoea, Diarrhoea, Bone Marrow Failure, Acute Respiratory Distress Syndrome, Decreased Appetite
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 800 mg
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-03-10
End date: 2012-03-20
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2012-04-01
End date: 2012-05-01
Nexavar
Dosage: 400 mg, qod
Start date: 2012-04-28
End date: 2012-04-30
Nexavar
Dosage: 200 mg, bid
Start date: 2012-03-29
End date: 2012-04-27
Other drugs received by patient: Silece; Risperidone; Zometa; Fentanyl Citrate; Lyrica; Loxonin; Lamivudine; Hepsera
Possible Nexavar side effects in 63 year old female
Reported by a physician from Japan on 2012-08-06
Patient: 63 year old female, weighing 48.1 kg (105.8 pounds)
Reactions: Blood Creatine Phosphokinase Increased, Angina Unstable, Palmar-Plantar Erythrodysaesthesia Syndrome, Wound Infection, Blood Creatine Phosphokinase MB Increased, Malaise, C-Reactive Protein Increased, Diarrhoea, Impaired Healing, Hepatectomy, Chest Pain, Platelet Count Decreased, Skin Necrosis, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 200-400 mg
Administration route: Oral
Start date: 2011-08-01
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
Indication: Metastases To Lung
Start date: 2011-03-05
End date: 2011-03-24
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Start date: 2011-03-17
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-01-07
End date: 2011-01-28
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Start date: 2011-04-22
Other drugs received by patient: Amlodipine; Miriplatin; Epirubicin Hydrochloride; Famotidine; Urepearl
Possible Nexavar side effects in 80 year old male
Reported by a physician from Japan on 2012-08-06
Patient: 80 year old male
Reactions: Malaise, Dysphonia, Diarrhoea, Haematuria, Pollakiuria, Bladder Cancer
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
End date: 2012-02-15
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
Start date: 2012-02-16
Nexavar
Dosage: 400 mg, qod
Administration route: Oral
Start date: 2012-04-01
End date: 2012-06-14
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-08-01
End date: 2011-08-10
Possible Nexavar side effects in 72 year old female
Reported by a consumer/non-health professional from France on 2012-08-01
Patient: 72 year old female
Reactions: Vomiting, Diarrhoea, Urinary Tract Infection, Pancytopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: unk
Start date: 2010-11-01
End date: 2012-05-25
Ofloxacin
Dosage: 200 mg, bid
Administration route: Oral
Indication: Urinary Tract Infection
Start date: 2012-05-23
End date: 2012-06-02
Other drugs received by patient: Levothyroxine Sodium; Vialebex; Lasix; Propranolol; Lantus; Folic Acid; Novorapid; Potassium Chloride
Possible Nexavar side effects in 85 year old male
Reported by a physician from Japan on 2012-07-31
Patient: 85 year old male
Reactions: Upper Limb Fracture, Diarrhoea, Fall, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-06-07
End date: 2011-08-30
Possible Nexavar side effects in 66 year old female
Reported by a consumer/non-health professional from United States on 2012-07-31
Patient: 66 year old female
Reactions: Blood Pressure Increased, Diarrhoea, Asthenia, Rash Pruritic
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
End date: 2012-07-15
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-07-13
Other drugs received by patient: Ramipril
Possible Nexavar side effects in 54 year old male
Reported by a consumer/non-health professional from United States on 2012-07-31
Patient: 54 year old male
Reactions: Pain in Extremity, DRY Skin, Hyperhidrosis, Abdominal Pain Upper, Dysphonia, Oropharyngitis Fungal, Diarrhoea, Gait Disturbance, Aphonia
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Prednisone TAB; Laxatives; Stool Softener; Morphine Sulfate; Lactulose
Possible Nexavar side effects in 74 year old male
Reported by a physician from Japan on 2012-07-30
Patient: 74 year old male
Reactions: Dyspnoea, Anaemia, Malaise, Cardiac Failure, Diarrhoea, Interstitial Lung Disease, Pneumonia Bacterial, Alopecia, Platelet Count Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: unk
Administration route: Oral
Indication: Renal Cell Carcinoma
Start date: 2011-12-05
End date: 2011-12-18
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2011-12-19
End date: 2012-05-09
Nexavar
Dosage: daily dose 400 mg
Administration route: Oral
Start date: 2012-05-30
End date: 2012-07-11
Other drugs received by patient: Sumiferon; Zoledronic Acid; Sumiferon; Sumiferon; Sumiferon
Possible Nexavar side effects in 67 year old female
Reported by a consumer/non-health professional from United States on 2012-07-30
Patient: 67 year old female
Reactions: Chills, Adverse Drug Reaction, Pyrexia, Oropharyngeal Spasm, Faeces Discoloured, Herpes Zoster, Dyspepsia, Cranial Nerve Disorder, Alpha 1 Foetoprotein Increased, Dizziness, Vulvovaginal Rash, Nausea, Pain of Skin, Musculoskeletal Discomfort, Skin Disorder, Rash, Hepatic Enzyme Increased, Diarrhoea, Thyroid Disorder, Hypertension
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, daily
Administration route: Oral
Indication: Hepatic Neoplasm Malignant non-Resectable
Start date: 2012-04-03
Nexavar
Nexavar
Dosage: 200 mg, bid
Start date: 2012-04-30
End date: 2012-05-15
Nexavar
Dosage: 400 mg, bid
End date: 2012-05-15
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2012-05-21
End date: 2012-05-22
Other drugs received by patient: Antihypertensives; Cardiac Therapy
Possible Nexavar side effects in 75 year old male
Reported by a physician from United States on 2012-07-30
Patient: 75 year old male
Reactions: Chest Discomfort, Dysphagia, Nausea, Pyrexia, Disorientation, Hypoaesthesia, Eructation, Fatigue, Malaise, Diarrhoea, Abdominal Distension, Gastrooesophageal Reflux Disease
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: unk
Start date: 2012-06-11
End date: 2012-07-19
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Start date: 2012-07-06
End date: 2012-07-09
Nexavar
Dosage: daily dose 600 mg (200 in am 400 in pm)
Indication: Hepatic Neoplasm Malignant
Start date: 2012-06-11
End date: 2012-06-22
Nexavar
Dosage: unk
Start date: 2012-07-21
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2012-07-02
End date: 2012-07-05
Other drugs received by patient: Glucophage
Possible Nexavar side effects in 59 year old female
Reported by a consumer/non-health professional from United States on 2012-07-25
Patient: 59 year old female
Reactions: Peripheral Coldness, Weight Decreased, Glossodynia, Vomiting, Nausea, Pain, Rash, Hyperhidrosis, Constipation, Erythema, Fatigue, Diarrhoea, Feeling Hot, Dehydration, Dizziness, Cold Sweat
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Start date: 2012-05-19
Nexavar
Dosage: 400 mg, qd
Indication: Hepatic Neoplasm Malignant
Start date: 2012-05-09
Nexavar
Dosage: 400 mg am and 200 mg pm
End date: 2012-07-11
Possible Nexavar side effects in 76 year old male
Reported by a physician from Colombia on 2012-07-24
Patient: 76 year old male, weighing 64.0 kg (140.8 pounds)
Reactions: Hyperkalaemia, Impetigo, Hepatic Failure, Renal Failure Chronic, Lividity, Hepatic Encephalopathy, Diarrhoea, Oedema Peripheral, Epistaxis
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Start date: 2010-01-30
End date: 2010-12-25
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-12-16
End date: 2010-01-27
Nexavar
Dosage: daily dose 800 mg
Start date: 2011-01-04
End date: 2011-01-11
Other drugs received by patient: Lactulosa; Furosemide; Enoxaparin; Insulin; Spironolactone; Ondansetron HCL; Midazolam; Dextrose 5%; Lactulosa; Propranolol; Midazolam; Furosemide; Dextrose 5%; Insulin; Haldol; Omeprazole; Spironolactone; Lactulosa; Haldol; Saline Solutions; NPH Insulin; Furosemide; Ampicillin and Sulbactam; Heparin; Acetylsalicylic Acid SRT; Diphenhydramine HCL
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