Index of reports
> Cases with Decreased Appetite (188)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Nexavar (Sorafenib) where reactions include decreased appetite. The selected reports were submitted to the FDA during the sample period of about a year.
Reports 1 - 30 of 188 Next >>
Possible Nexavar side effects in 54 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27
Patient: 54 year old male
Reactions: Blood Pressure Increased, Weight Decreased, Nausea, Pain in Extremity, Hypotension, Rash, Skin Irritation, Frequent Bowel Movements, Fatigue, Diarrhoea, Gait Disturbance, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 73 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-24
Patient: 73 year old female, weighing 48.0 kg (105.6 pounds)
Reactions: Hyperbilirubinaemia, Alanine Aminotransferase Increased, Aspartate Aminotransferase Increased, Palmar-Plantar Erythrodysaesthesia Syndrome, General Physical Health Deterioration, Encephalopathy, Dizziness, Hypertension, Decreased Appetite
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2010-01-08
End date: 2010-01-10
Nexavar
Dosage: 800 mg, qd
Administration route: Oral
Start date: 2010-01-13
End date: 2010-01-19
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Start date: 2010-01-20
End date: 2010-03-02
Other drugs received by patient: Aldactone; Shakuyakukanzoutou; Omeprazole; Urso 250; Medicon; Allegra; Acetaminophen; Onealfa
Possible Nexavar side effects in 63 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-21
Patient: 63 year old female, weighing 48.1 kg (105.8 pounds)
Reactions: Blood Creatine Phosphokinase Increased, Angina Unstable, Palmar-Plantar Erythrodysaesthesia Syndrome, Wound Infection, Blood Creatine Phosphokinase MB Increased, Malaise, C-Reactive Protein Increased, Diarrhoea, Impaired Healing, Hepatectomy, Chest Pain, Platelet Count Decreased, Skin Necrosis, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-01-07
End date: 2011-01-28
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Indication: Metastases To Lung
Start date: 2011-03-05
End date: 2011-03-24
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Start date: 2011-03-17
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-04-22
End date: 2011-08-22
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-10-25
End date: 2011-10-30
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-08-31
End date: 2011-10-23
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2011-11-03
Other drugs received by patient: Urepearl; Epirubicin Hydrochloride; Famotidine; Amlodipine; Miriplatin
Possible Nexavar side effects in 58 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20
Patient: 58 year old male
Reactions: Weight Decreased, Fatigue, Neck Pain, Musculoskeletal Stiffness, Blood Glucose Fluctuation, Gallbladder Disorder, Gastrooesophageal Reflux Disease, Muscle Spasms, Decreased Appetite, Back Pain, Vomiting, Nausea, DRY Skin, Anxiety, Insomnia, Asthenia
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 53 year old male
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 53 year old male
Reactions: Confusional State, Agitation, Dysphagia, Pain, Anaemia, Failure To Thrive, Hypokalaemia, Death, Fatigue, Fluid Intake Reduced, Asthenia, Decreased Appetite, Deep Vein Thrombosis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg am, 200 mg pm x 21days
Indication: Colorectal Cancer Metastatic
Start date: 2012-06-22
End date: 2012-08-07
Xeloda
Dosage: 1500 mg am, 1650 mg pm x 14 days
Indication: Colorectal Cancer Metastatic
Start date: 2012-06-22
End date: 2012-08-01
Other drugs received by patient: Roxicodone; Compazine; Ferrous Fumarate; MS Contin; Phenergan HCL; Prinzide; Multi-Vitamin; Compazine
Possible Nexavar side effects in 63 year old male
Reported by a health professional (non-physician/pharmacist) from Brazil on 2012-08-17
Patient: 63 year old male, weighing 67.0 kg (147.4 pounds)
Reactions: Weight Decreased, Blood Pressure Increased, Abdominal Pain, Back Pain, Urinary Tract Infection, Diplopia, Diarrhoea, Metastases To Bone, Eye Disorder, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Preparations Increasing Uric Acid Excretion; Omeprazole; Captopril; Hydrochlorothiazide; Preparations Increasing Uric Acid Excretion; Preparations Increasing Uric Acid Excretion; Preparations Increasing Uric Acid Excretion; Hydrochlorothiazide
Possible Nexavar side effects in 60 year old male
Reported by a physician from United States on 2012-08-15
Patient: 60 year old male
Reactions: Weight Decreased, Cellulitis, Retching, Pain in Extremity, Pyrexia, Fall, Erythema, Diarrhoea, Oedema Peripheral, Asthenia, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Analgesics
Possible Nexavar side effects in 54 year old male
Reported by a physician from Japan on 2012-08-13
Patient: 54 year old male, weighing 40.5 kg (89.1 pounds)
Reactions: Blood Bilirubin Increased, Blood Alkaline Phosphatase Increased, Pneumonia, Hepatic Function Abnormal, Anaemia, Constipation, Ascites, Diarrhoea, Platelet Count Decreased, Metastases To Bone, Liver Carcinoma Ruptured, Bilirubin Conjugated Increased, Decreased Appetite
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-10
End date: 2009-09-10
Nexavar
Dosage: 600 mg, qd
Administration route: Oral
Start date: 2009-09-12
End date: 2009-09-25
Other drugs received by patient: Fentanyl-100; TPN; Zolpidem; Bismuth Subnitrate; Voltaren; Lansoprazole; Albumin Tannate; Oxycodone Hydrochloride; Elemenmic
Possible Nexavar side effects in 64 year old male
Reported by a pharmacist from Japan on 2012-08-09
Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Diarrhoea, Hepatic Neoplasm Malignant, Hyperammonaemia, Eczema, Decreased Appetite, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-09-09
End date: 2009-10-01
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-10-28
End date: 2009-10-30
Nexavar
Dosage: 600 mg/day
Administration route: Oral
Start date: 2009-10-02
End date: 2009-10-27
Nexavar
Dosage: 800 mg/day
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-06
End date: 2009-09-08
Other drugs received by patient: Lamivudine; Mucosta; Aldactone; Lasix; Oxycontin; Rabeprazole Sodium; Loxoprofen; Fentanyl-100; Pastaron; Ensure [minerals Nos,vitamins Nos]; Hepsera; Hypoca; Morphine; Aldactone
Possible Nexavar side effects in 62 year old male
Reported by a physician from Japan on 2012-08-08
Patient: 62 year old male, weighing 57.0 kg (125.4 pounds)
Reactions: Fatigue, Dyspnoea, Diarrhoea, Bone Marrow Failure, Acute Respiratory Distress Syndrome, Decreased Appetite
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 800 mg
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2012-03-10
End date: 2012-03-20
Nexavar
Dosage: 200 mg, bid
Administration route: Oral
Start date: 2012-04-01
End date: 2012-05-01
Nexavar
Dosage: 400 mg, qod
Start date: 2012-04-28
End date: 2012-04-30
Nexavar
Dosage: 200 mg, bid
Start date: 2012-03-29
End date: 2012-04-27
Other drugs received by patient: Silece; Risperidone; Zometa; Fentanyl Citrate; Lyrica; Loxonin; Lamivudine; Hepsera
Possible Nexavar side effects in 63 year old female
Reported by a physician from Japan on 2012-08-06
Patient: 63 year old female, weighing 48.1 kg (105.8 pounds)
Reactions: Blood Creatine Phosphokinase Increased, Angina Unstable, Palmar-Plantar Erythrodysaesthesia Syndrome, Wound Infection, Blood Creatine Phosphokinase MB Increased, Malaise, C-Reactive Protein Increased, Diarrhoea, Impaired Healing, Hepatectomy, Chest Pain, Platelet Count Decreased, Skin Necrosis, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: daily dose 200-400 mg
Administration route: Oral
Start date: 2011-08-01
Nexavar
Dosage: daily dose 600 mg
Administration route: Oral
Indication: Metastases To Lung
Start date: 2011-03-05
End date: 2011-03-24
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Start date: 2011-03-17
Nexavar
Dosage: 200 mg, tid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-01-07
End date: 2011-01-28
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Start date: 2011-04-22
Other drugs received by patient: Amlodipine; Miriplatin; Epirubicin Hydrochloride; Famotidine; Urepearl
Possible Nexavar side effects in 85 year old male
Reported by a physician from Japan on 2012-07-31
Patient: 85 year old male
Reactions: Upper Limb Fracture, Diarrhoea, Fall, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Nexavar
Dosage: 400 mg, bid
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-06-07
End date: 2011-08-30
Possible Nexavar side effects in 59 year old male
Reported by a physician from United States on 2012-07-27
Patient: 59 year old male, weighing 126.8 kg (279.0 pounds)
Reactions: Myalgia, Blood Bilirubin Increased, Fatigue, Ammonia Increased, Encephalopathy, Decreased Appetite, Lethargy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Hydrochlorothiazide; Losartan Potassium and Hydrochlorothiazide; Protonix
Possible Nexavar side effects in 75 year old male
Reported by a physician from Japan on 2012-07-24
Patient: 75 year old male, weighing 53.2 kg (117.0 pounds)
Reactions: Fatigue, Vomiting, Stomatitis, Ileus, Nausea, Hepatic Neoplasm Malignant, Palmar-Plantar Erythrodysaesthesia Syndrome, Decreased Appetite
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 800 mg (daily dose), , oral
Administration route: Oral
Start date: 2009-08-03
End date: 2009-08-18
Nexavar
Dosage: 800 mg (daily dose), , oral
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-07-30
End date: 2009-07-31
Oxycontin
Dosage: since before nexavar administration
Administration route: Oral
Indication: Pain Management
End date: 2009-08-17
Oxycontin
Dosage: 160 mg (daily dose), , unknown
Start date: 2009-08-18
End date: 2009-08-23
Other drugs received by patient: Sennoside; Sepamit; Gabapentin; Amitriptyline HCL; Keratinamin; Voltaren; Omeprazole; Maglax; Fentanyl-100; Mucosta; Loxonin; Fentanyl-100; Oxycodone Hydrochloride; Anpec
Possible Nexavar side effects in 70 year old male
Reported by a physician from Japan on 2012-07-23
Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)
Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Hypertension, Blood Creatinine Increased, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Urepearl; Pydoxal; Rabeprazole Sodium; Betamethasone Sodium Phosphate; Mobic
Possible Nexavar side effects in 85 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-23
Patient: 85 year old male, weighing 45.0 kg (99.0 pounds)
Reactions: Death, Amylase Increased, Platelet Count Decreased, Decreased Appetite
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Hirudoid; Losartan Potassium
Possible Nexavar side effects in 70 year old male
Reported by a physician from Japan on 2012-07-19
Patient: 70 year old male, weighing 64.7 kg (142.3 pounds)
Reactions: White Blood Cell Count Decreased, Diabetes Mellitus, Nephrotic Syndrome, Haemoglobin Decreased, Fatigue, Blood Creatinine Increased, Hypertension, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Betamethasone Sodium Phosphate; Pydoxal; Rabeprazole Sodium; Mobic; Urepearl
Possible Nexavar side effects in 74 year old female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-19
Patient: 74 year old female
Reactions: Abdominal Pain, Weight Decreased, Hepatic Neoplasm Malignant, Portal Vein Thrombosis, Musculoskeletal Pain, Pyrexia, Headache, Ascites, Hepatic Enzyme Increased, Diarrhoea, Asthenia, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 60 year old male
Reported by a consumer/non-health professional from United States on 2012-07-17
Patient: 60 year old male
Reactions: Cellulitis, Retching, Pyrexia, Erythema, Fall, Diarrhoea, Oedema Peripheral, Asthenia, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Pain Medication
Possible Nexavar side effects in 66 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-16
Patient: 66 year old female
Reactions: Abdominal Pain, Weight Decreased, Blood Urine Present, Skin Exfoliation, Flatulence, Rash, Dysgeusia, Abdominal Discomfort, Hair Texture Abnormal, Diarrhoea, Alopecia, Dermatitis Bullous, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Coumadin; Metformin Hydrochloride
Possible Nexavar side effects in 59 year old male
Reported by a physician from Japan on 2012-07-16
Patient: 59 year old male
Reactions: Pneumocystis Jiroveci Pneumonia, Nausea, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Antihypertensives; ALL Other Therapeutic Products
Possible Nexavar side effects in 63 year old male
Reported by a physician from Japan on 2012-07-13
Patient: 63 year old male, weighing 67.5 kg (148.5 pounds)
Reactions: Hyperbilirubinaemia, Vomiting, Nausea, Alanine Aminotransferase Increased, Hepatic Failure, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Dysphonia, Aspartate Aminotransferase Increased, Decreased Appetite
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Maglax; Keratinamin; Norvasc; NEO-Minophagen C; Oxycontin; Loxoprofen; Famotidine; Candesartan Cilexetil; Urso 250; Oxycodone Hydrochloride; Evamyl; NEO-Minophagen C; Laxoberon; Trichlormethiazide; Flivastatin Sodium; Oxycontin; Oxycontin; NEO-Minophagen C
Possible Nexavar side effects in 51 year old male
Reported by a consumer/non-health professional from United States on 2012-07-11
Patient: 51 year old male
Reactions: Aphagia, Pruritus, Nausea, Skin Exfoliation, Rash, Pruritus Genital, Fatigue, Feeling Hot, Rash Maculo-Papular, Decreased Appetite, Blister
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Diuretics
Possible Nexavar side effects in 74 year old male
Reported by a physician from Japan on 2012-07-06
Patient: 74 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Hepatic Neoplasm Malignant, Hyperkalaemia, Disseminated Intravascular Coagulation, International Normalised Ratio Increased, Pyrexia, Hypernatraemia, Diarrhoea, Sepsis, Metastases To Central Nervous System, Decreased Appetite
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Digoxin; Lasix; Oxycontin; Magnesium Oxide; Motilium; Warfarin Sodium; Alosenn; Aldactone; Oxycodone Hydrochloride; Oxycodone Hydrochloride; Polaramine; Prochlorperazine; Lansoprazole
Possible Nexavar side effects in 59 year old male
Reported by a physician from United States on 2012-07-05
Patient: 59 year old male, weighing 126.8 kg (279.0 pounds)
Reactions: Blood Bilirubin Increased, Myalgia, Fatigue, Encephalopathy, Ammonia Increased, Decreased Appetite, Lethargy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Other drugs received by patient: Protonix; Hydrochlorothiazide; Losartan Potassium
Possible Nexavar side effects in 64 year old male
Reported by a pharmacist from Japan on 2012-07-02
Patient: 64 year old male, weighing 62.0 kg (136.4 pounds)
Reactions: Hepatic Neoplasm Malignant, Diarrhoea, Hyperammonaemia, Palmar-Plantar Erythrodysaesthesia Syndrome, Eczema, Decreased Appetite, Ascites
Adverse event resulted in: death
Drug(s) suspected as cause:
Nexavar
Dosage: 800 mg/day
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2009-08-06
End date: 2009-09-08
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-10-28
End date: 2009-10-30
Nexavar
Dosage: 600 mg/day
Administration route: Oral
Start date: 2009-10-02
End date: 2009-10-27
Nexavar
Dosage: 400 mg/day
Administration route: Oral
Start date: 2009-09-09
End date: 2009-10-01
Other drugs received by patient: Pastaron; Morphine; Fentanyl-100; Aldactone; Rabeprazole Sodium; Mucosta; Ensure [minerals Nos,vitamins Nos]; Hypoca; Aldactone; Lamivudine; Oxycontin; Hepsera; Loxoprofen; Lasix
Possible Nexavar side effects in 74 year old female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-02
Patient: 74 year old female
Reactions: Abdominal Pain Lower, Weight Decreased, Blood Pressure Systolic Increased, Musculoskeletal Pain, Portal Vein Thrombosis, Pyrexia, Headache, Disease Progression, Ascites, Hepatic Enzyme Increased, Diarrhoea, Asthenia, Decreased Appetite
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 81 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-28
Patient: 81 year old male
Reactions: Weight Decreased, Hepatic Neoplasm Malignant, Cystitis, Convulsion, Fatigue, Dehydration, Asthenia, White Blood Cell Count Increased, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Possible Nexavar side effects in 79 year old female
Reported by a pharmacist from Japan on 2012-06-25
Patient: 79 year old female, weighing 47.0 kg (103.4 pounds)
Reactions: Palmar-Plantar Erythrodysaesthesia Syndrome, Lumbar Vertebral Fracture, Epilepsy, Transient Ischaemic Attack, Decreased Appetite
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Nexavar
Dosage: 400 mg, qd
Administration route: Oral
Indication: Hepatic Neoplasm Malignant
Start date: 2011-09-06
End date: 2011-09-12
Nexavar
Dosage: 200 mg, qd
Start date: 2011-09-13
End date: 2011-11-02
Nexavar
Dosage: 200 mg, qd
Start date: 2012-01-11
End date: 2012-01-18
Other drugs received by patient: Ursamic; Lasix; Trichlormethiazide; Lansoprazole; Tolterodine Tartrate; Olmesartan Medoxomil; Amlodipine
Possible Nexavar side effects in 70 year old male
Reported by a physician from Japan on 2012-06-22
Patient: 70 year old male
Reactions: Haemoglobin Decreased, Gastric Ulcer Haemorrhage, Duodenal Ulcer, Gastric Ulcer, Decreased Appetite, Faeces Discoloured
Drug(s) suspected as cause:
Nexavar
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