This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Neupro (Rotigotine) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (167)
Death (21)
Life Threatening Events (7)
Disability (4)
Reports by Reaction Type
Drug Ineffective (12),
Parkinson's Disease (12),
Sopor (8),
Pruritus (7),
Somnolence (7),
Dyspnoea (7),
Atrial Fibrillation (7),
Urticaria (6),
Erythema (6),
Fall (6),
Application Site Pruritus (6),
Death (6)
Below are a few examples of reports where side effects / adverse reactions may be related to Neupro (Rotigotine). For a complete list or a specific selection of reports, please use the links above.
Possible Neupro side effects in 64 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-27
Patient: 64 year old female
Reactions: Self-Injurious Ideation
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Stalevo 100
Possible Neupro side effects in 64 year old male
Reported by a consumer/non-health professional from Netherlands on 2012-08-24
Patient: 64 year old male
Reactions: Syncope, Vomiting, Listless, Drug Ineffective, Restless Legs Syndrome, Seizure Like Phenomena
Drug(s) suspected as cause:
Neupro
Possible Neupro side effects in male
Reported by a consumer/non-health professional from Netherlands on 2012-08-17
Patient: male
Reactions: Vomiting, Syncope, Listless, Seizure Like Phenomena
Drug(s) suspected as cause:
Neupro
Possible Neupro side effects in 56 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-17
Patient: 56 year old female
Reactions: Death
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Venlafaxine; Trospium Chloride; Solifenacin Succinate; Carbidopa and Levodopa; Carbidopa and Levodopa; Venlafaxine; Rasagiline
Possible Neupro side effects in 56 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 56 year old female, weighing 77.1 kg (169.6 pounds)
Reactions: Confusional State, Thrombosis, Fall, Somnolence, Resuscitation
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Trospium-Sanctura; Solifenacin Succinate; Effexor; Rasagiline-Azilect; Sinemet; Sinemet
Possible Neupro side effects in female
Reported by a consumer/non-health professional from Australia on 2012-08-14
Patient: female
Reactions: Drug Hypersensitivity, Lung Neoplasm
Drug(s) suspected as cause:
Neupro
Possible Neupro side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-09
Patient: female
Reactions: Self-Injurious Ideation
Drug(s) suspected as cause:
Neupro
Possible Neupro side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-09
Patient: female
Reactions: Drug Ineffective, Application Site Pruritus, Ovarian Cancer
Drug(s) suspected as cause:
Neupro
Neupro
Start date: 2012-07-16
End date: 2012-07-01
Neupro
Start date: 2012-07-01
End date: 2012-01-01
Possible Neupro side effects in 65 year old female
Reported by a physician from Germany on 2012-08-03
Patient: 65 year old female, weighing 69.0 kg (151.8 pounds)
Reactions: Breast Cancer
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupro
Start date: 2010-11-20
End date: 2010-11-26
Neupro
Start date: 2011-03-16
End date: 2011-06-28
Neupro
Indication: Parkinson's Disease
Start date: 2011-01-01
Neupro
Start date: 2011-06-29
End date: 2011-09-20
Neupro
Start date: 2011-09-21
End date: 2011-01-01
Neupro
Start date: 2010-11-27
End date: 2011-03-15
Other drugs received by patient: Stalevo 100; Ergocalciferol; Calcium D3; PK Merz; Cosopt; Levocomp; Levocomp Retard; PK Merz; Alendron; Calcimagon D3; Levocomp Retard; Madopar LT
Possible Neupro side effects in male
Reported by a consumer/non-health professional from Germany on 2012-07-31
Patient: male
Reactions: Death, Rash
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupro
Start date: 2008-10-01
End date: 2008-01-01
Neupro
Start date: 2008-01-01
Neupro
Start date: 2008-01-01
End date: 2008-01-01
Neupro
Start date: 2008-01-01
End date: 2008-01-01
Possible Neupro side effects in 77 year old female
Reported by a physician from Germany on 2012-07-30
Patient: 77 year old female, weighing 61.0 kg (134.2 pounds)
Reactions: Dyspnoea, Cardiac Failure, Loss of Consciousness
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Aspirin
Indication: Cardiac Disorder
Bisoprolol Fumarate
Indication: Arrhythmia
Digitoxin TAB
Indication: Cardiac Disorder
Diovan
Indication: Hypertension
Start date: 2010-05-20
Falithrom
Indication: Cardiac Failure
Start date: 2010-05-20
End date: 2010-06-09
Isosorbide Dinitrate
Indication: Hypertension
Start date: 2010-05-20
End date: 2010-06-09
Neupro
Indication: Parkinson's Disease
Start date: 2010-04-09
End date: 2010-05-05
Neupro
Start date: 2010-05-28
Neupro
Start date: 2010-05-06
End date: 2010-05-27
Torsemide
Indication: Hypertension
Other drugs received by patient: Pantoprazole; Ramipril; Felopuren; Simvastatin; Allopurinol; Nephrotrans; Valproate Sodium
Possible Neupro side effects in 57 year old male
Reported by a physician from Germany on 2012-07-30
Patient: 57 year old male
Reactions: Parkinson's Disease
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Clarium
Indication: Parkinson's Disease
Start date: 2008-11-04
End date: 2008-11-08
Clarium
Start date: 2008-11-11
End date: 2009-03-12
Clarium
Start date: 2008-11-09
End date: 2008-11-10
Clarium
Dosage: dose decreased
Start date: 2010-10-04
Clarium
Dosage: frequency: other 2-1-1
Start date: 2009-11-10
End date: 2010-10-03
Clarium
Dosage: frequency: other 2-0-1
Start date: 2009-05-09
End date: 2009-11-09
Clarium
Dosage: dose: other 2-1-1
Start date: 2009-03-13
End date: 2009-06-08
Neupro
Start date: 2009-05-01
End date: 2009-05-07
Neupro
Start date: 2010-10-12
End date: 2010-10-12
Neupro
Start date: 2009-06-26
End date: 2010-10-04
Neupro
Start date: 2010-10-05
End date: 2010-10-07
Neupro
Start date: 2010-10-13
End date: 2010-10-13
Neupro
Start date: 2008-06-09
End date: 2008-06-19
Neupro
Start date: 2008-06-20
End date: 2008-06-22
Neupro
Start date: 2009-06-08
End date: 2009-06-25
Neupro
Start date: 2010-10-08
End date: 2010-10-11
Neupro
Start date: 2010-10-18
Neupro
Start date: 2008-06-23
End date: 2008-11-02
Neupro
Start date: 2009-03-03
End date: 2009-04-30
Neupro
Start date: 2010-10-14
End date: 2010-10-17
Neupro
Indication: Parkinson's Disease
Start date: 2008-06-04
End date: 2008-06-08
Neupro
Start date: 2008-11-10
End date: 2009-03-02
Neupro
Start date: 2008-11-03
End date: 2008-11-09
Primidone
Start date: 2008-11-04
End date: 2008-11-10
Primidone
Indication: Parkinson's Disease
Start date: 2008-07-07
End date: 2008-07-08
Primidone
Dosage: dose: other 2-0-1
Start date: 2008-09-16
End date: 2008-11-03
Primidone
Start date: 2008-07-10
End date: 2008-09-01
Primidone
Dosage: other 1-0-2
Start date: 2010-07-21
End date: 2010-09-20
Primidone
Start date: 2010-09-21
End date: 2010-10-04
Primidone
Start date: 2010-10-08
Primidone
Start date: 2008-11-11
End date: 2010-04-22
Primidone
Start date: 2008-07-09
End date: 2008-07-09
Primidone
Start date: 2010-04-23
End date: 2010-07-20
Primidone
Start date: 2010-10-05
End date: 2010-10-07
Selegelin
Indication: Parkinson's Disease
Start date: 2008-11-14
End date: 2010-10-04
Other drugs received by patient: Levothyroxine Sodium; Madopar Depot; Clonazepam; Protaphane; Madopar Depot; Protaphane; Novorapid; Clonazepam; Moviprep; Madopar Depot; Levothyroxine Sodium; Madopar Depot
Possible Neupro side effects in 69 year old female
Reported by a physician from Germany on 2012-07-25
Patient: 69 year old female, weighing 70.0 kg (154.0 pounds)
Reactions: Drug Intolerance
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Doxepin; Plavix; Enaplus; Jodid; Lacidipin; Simvastatin; Motens; Benalapril
Possible Neupro side effects in 62 year old male
Reported by a physician from Sweden on 2012-07-25
Patient: 62 year old male
Reactions: Aphasia, Headache
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Ibuprofen; Omeprazole; Panodil Film-Coated Tablet; Koffein Recip Tablet 100 MG
Possible Neupro side effects in male
Reported by a consumer/non-health professional from Germany on 2012-07-24
Patient: male, weighing 110.0 kg (242.0 pounds)
Reactions: Application Site Reaction, Dermatitis Allergic, Pathological Gambling, Libido Increased, Erectile Dysfunction
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Citalopram Hydrobromide; Tamsolusin Retard; Stalevo 100; Omeprazole; Levodop Retard; Metoprolol Succinate; Aspirin; Bromazanil; Amantadine HCL; Tambocor
Possible Neupro side effects in 74 year old male
Reported by a pharmacist from France on 2012-07-23
Patient: 74 year old male, weighing 78.0 kg (171.6 pounds)
Reactions: Paraesthesia
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Omeprazole; Lasix; Zoladex; Arixtra; Tilcotil; Stalevo 100; Crestor; Anti-Diabetic Drug; Zolpidem
Possible Neupro side effects in 62 year old male
Reported by a physician from Sweden on 2012-07-20
Patient: 62 year old male
Reactions: Aphasia, Headache
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupro
Dosage: reduced dose
Neupro
Indication: Parkinson's Disease
Other drugs received by patient: Omeprazole; Ibuprofen; Panodil Film-Coated Tablet; Koffein Recip Tablet 100 MG
Possible Neupro side effects in 80 year old male
Reported by a consumer/non-health professional from France on 2012-07-17
Patient: 80 year old male
Reactions: Nightmare, Somnolence, Fall, Decubitus Ulcer, Oedema Peripheral, Extrapyramidal Disorder, Deep Vein Thrombosis, Muscle Spasms
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupro
Indication: Parkinson's Disease
Start date: 2012-05-21
End date: 2012-05-01
Neupro
Start date: 2011-01-01
End date: 2012-05-01
Other drugs received by patient: Sinemet; Nexium; Motilium; Sinemet
Possible Neupro side effects in 74 year old female
Reported by a physician from France on 2012-07-13
Patient: 74 year old female
Reactions: Application Site Reaction, Application Site Vesicles, Application Site Pruritus
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Sinemet
Possible Neupro side effects in 85 year old female
Reported by a consumer/non-health professional from Germany on 2012-07-13
Patient: 85 year old female
Reactions: Ill-Defined Disorder, Erythema, Application Site Pruritus, Application Site Irritation
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupro
Dosage: 8 mg/24 h
Start date: 2007-01-01
Neupro
Dosage: 4 mg/24 h
Other drugs received by patient: Pramipexole Dihydrochloride; Madopar; Entacapone
Possible Neupro side effects in 76 year old female
Reported by a consumer/non-health professional from Germany on 2012-07-09
Patient: 76 year old female, weighing 83.0 kg (182.6 pounds)
Reactions: Product Quality Issue, Pruritus, Application Site Pustules, Alanine Aminotransferase Increased, Urticaria, Muscular Weakness, Skin Burning Sensation, Product Adhesion Issue, Erythema, Transaminases Increased, Tremor, Gamma-Glutamyltransferase Increased, Medication Error, Alopecia, Aspartate Aminotransferase Increased
Drug(s) suspected as cause:
Neupro
Indication: Parkinson's Disease
Start date: 2012-04-01
Neupro
Start date: 2012-04-10
End date: 2012-04-25
Neupro
Dosage: once daily at 06:00am
Start date: 2012-03-10
End date: 2012-01-01
Other drugs received by patient: Torsemide; Ergocalciferol; Omeprazole; Novalgin; Omega 3 KPS; Madopar LT; Aspirin; Madopar; Metoprolol Tartrate; Diovan; Pantoprazole Sodium; Estradiol; Diasporal Dinkt
Possible Neupro side effects in 68 year old male
Reported by a physician from Germany on 2012-07-06
Patient: 68 year old male, weighing 94.0 kg (206.8 pounds)
Reactions: Pleural Effusion
Drug(s) suspected as cause:
Neupro
Other drugs received by patient: Parkinsan; Selegilin; Lormetazepam; Carbidopa and Levodopa
Possible Neupro side effects in 85 year old female
Reported by a health professional (non-physician/pharmacist) from Germany on 2012-07-06
Patient: 85 year old female
Reactions: Erythema, Ill-Defined Disorder, Application Site Pruritus, Skin Irritation
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupro
Dosage: 8 mg
Neupro
Dosage: 4 mg
Possible Neupro side effects in 29 year old female
Reported by a pharmacist from France on 2012-07-05
Patient: 29 year old female
Reactions: Pruritus, Application Site Swelling, Application Site Oedema, Aphonia
Drug(s) suspected as cause:
Neupro
Start date: 2012-02-06
End date: 2012-02-01
Neupro
Dosage: progressively increased dose
Start date: 2012-02-01
End date: 2012-02-01
Neupro
Indication: Parkinson's Disease
Start date: 2012-02-01
End date: 2012-04-13
Other drugs received by patient: Azilect
Possible Neupro side effects in male
Reported by a consumer/non-health professional from Germany on 2012-07-03
Patient: male, weighing 78.0 kg (171.6 pounds)
Reactions: Pruritus, Dermatitis, Application Site Erythema, Application Site Pruritus
Drug(s) suspected as cause:
Neupro
Indication: Parkinson's Disease
Start date: 2011-06-01
Neupro
Indication: Restless Legs Syndrome
Start date: 2011-06-01
Other drugs received by patient: Ropinirol; Tilidin; Ropinirol; Tilidin; Clonazepam
Possible Neupro side effects in 76 year old female
Reported by a consumer/non-health professional from Germany on 2012-06-26
Patient: 76 year old female, weighing 83.0 kg (182.6 pounds)
Reactions: Pruritus, Application Site Pustules, Urticaria, Muscular Weakness, Skin Burning Sensation, Product Adhesion Issue, Erythema, Tremor, Medication Error, Gamma-Glutamyltransferase Increased, Alopecia, Hypertransaminasaemia
Drug(s) suspected as cause:
Neupro
Indication: Parkinson's Disease
Start date: 2012-04-01
Neupro
Start date: 2012-04-10
End date: 2012-04-25
Neupro
Dosage: once daily at 06:00am
Start date: 2012-03-10
End date: 2012-01-01
Other drugs received by patient: Madopar; Novalgin; Madopar LT; Estradiol; Torsemide; Pantoprazole; Diovan; Omeprazole; Ergocalciferol; Metoprolol Tartrate; Aspirin; Diasporal Dinkt; Omega 3 KPS
Possible Neupro side effects in female
Reported by a physician from Germany on 2012-06-26
Patient: female
Reactions: Impulse-Control Disorder, Kleptomania, Pathological Gambling
Drug(s) suspected as cause:
Carbidopa and Levodopa
Dosage: daily dose: 750 mg
Administration route: Oral
Indication: Parkinson's Disease
Madopar LT
Dosage: 5x1
Administration route: Oral
Indication: Parkinson's Disease
Neupro
Dosage: 8 mg/24 hour
Indication: Parkinson's Disease
Requip
Dosage: single dose 8
Administration route: Oral
Indication: Parkinson's Disease
Tasmar
Administration route: Oral
Indication: Parkinson's Disease
Other drugs received by patient: PK-Merz; Lactulose
Possible Neupro side effects in female
Reported by a physician from Germany on 2012-06-26
Patient: female
Reactions: Impulse-Control Disorder, Kleptomania, Pathological Gambling, Theft
Drug(s) suspected as cause:
Carbidopa and Levodopa
Dosage: 125mg unknown
Administration route: Oral
Indication: Parkinson's Disease
Madopar
Dosage: 125mg five times per day
Administration route: Oral
Indication: Parkinson's Disease
Neupro
Dosage: 8mg per day
Indication: Parkinson's Disease
Requip
Dosage: 8mg three times per day
Administration route: Oral
Indication: Parkinson's Disease
Tasmar
Dosage: 100mg three times per day
Administration route: Oral
Indication: Parkinson's Disease
Other drugs received by patient: Lactulose; L-Dopa; PK-Merz
Possible Neupro side effects in 74 year old male
Reported by a physician from Germany on 2012-06-14
Patient: 74 year old male, weighing 120.0 kg (264.0 pounds)
Reactions: Multi-Organ Failure, Cardiac Failure
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupro
Start date: 2006-12-11
End date: 2008-11-11
Neupro
Start date: 2008-11-12
End date: 2008-11-26
Neupro
Dosage: 1/2
Indication: Parkinson's Disease
Start date: 2006-11-27
End date: 2006-12-10
Other drugs received by patient: Torsemide; PK Levo; PK Levo; Marcumar; Stalevo 100; Calcium Brause; Spiriva; Amlodipine; HCT Ratio; Allopurinol; Ramipril; PK Levo; Ramipril; Torsemide; Azilect; Pantoprazole; Ergocalciferol; Loftan; Bronchoretard
Possible Neupro side effects in 74 year old male
Reported by a physician from Germany on 2012-06-14
Patient: 74 year old male, weighing 120.0 kg (264.0 pounds)
Reactions: Cardiac Failure
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Neupro
Indication: Parkinson's Disease
Start date: 2008-11-12
End date: 2008-11-26
Neupro
Start date: 2006-12-11
End date: 2008-11-11
Neupro
Dosage: 1/2 patch
Start date: 2006-11-27
End date: 2006-12-10
Other drugs received by patient: Ramipril; HCT Ratio; Azilect; Ergocalciferol; Torsemide; PK Levo; PK Levo; Amlodipine; Stalevo 100; Marcumar; PK Levo
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