This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Neupogen (Filgrastim) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (850)
Death (77)
Life Threatening Events (34)
Disability (8)
Reports by Reaction Type
Febrile Neutropenia (89),
Neutropenia (70),
Pneumonia (65),
Pyrexia (53),
White Blood Cell Count Decreased (49),
Deep Vein Thrombosis (44),
Drug Ineffective (41),
Diarrhoea (38),
Bone Pain (36),
Infection (35),
Leukopenia (35),
Malaise (29)
Below are a few examples of reports where side effects / adverse reactions may be related to Neupogen (Filgrastim). For a complete list or a specific selection of reports, please use the links above.
Possible Neupogen side effects in 62 year old female
Reported by a physician from Finland on 2012-08-27
Patient: 62 year old female
Reactions: Back Pain, Dysphagia, Stomatitis, Dyspnoea, Pain in Extremity, Hypotension, Bone Pain, Constipation, Abdominal Pain Upper, Joint Stiffness, Myalgia, Malaise, Insomnia, Oedema Peripheral, Musculoskeletal Stiffness, Gait Disturbance, Candidiasis
Drug(s) suspected as cause:
Docetaxel
Dosage: 80 mg/m2, unk
Indication: Metastasis
Start date: 2012-04-26
End date: 2012-04-28
Neulasta
Dosage: 6 mg, unk
Indication: Chemotherapy
Start date: 2012-04-28
End date: 2012-06-11
Neupogen
Dosage: unk
Indication: Chemotherapy
Start date: 2012-07-21
End date: 2012-07-27
Possible Neupogen side effects in female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-27
Patient: female
Reactions: Therapeutic Response Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 62 year old female
Reported by a pharmacist from Canada on 2012-08-27
Patient: 62 year old female, weighing 119.0 kg (261.8 pounds)
Reactions: Back Pain, Hypersensitivity, Vomiting, Nausea, Hypotension, Tachycardia, Hyperhidrosis, Heart Rate Increased, Dizziness, Tachypnoea, Hypertension, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Other drugs received by patient: Dilaudid; Gabapentin; Dexamethasone; Levemir; Granisetron; Cesamet
Possible Neupogen side effects in male
Reported by a physician from Netherlands on 2012-08-27
Patient: male, weighing 95.0 kg (209.0 pounds)
Reactions: Cranial Nerve Disorder
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: third maintenance cycle
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2010-09-06
Cyclophosphamide
Doxorubicin HCL
Indication: Diffuse Large B-Cell Lymphoma
Doxorubicin HCL
Dosage: third maintenance cycle
Start date: 2010-09-06
Neupogen
Indication: Diffuse Large B-Cell Lymphoma
Neupogen
Dosage: third maintenance cycle
Start date: 2010-09-07
Prednisone TAB
Administration route: Oral
Indication: Diffuse Large B-Cell Lymphoma
Prednisone TAB
Dosage: third maintenance cycle
Administration route: Oral
Start date: 2010-09-06
Rituximab
Dosage: third maintenance cycle
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2010-09-06
Rituximab
Start date: 2010-11-29
End date: 2011-03-21
Vincristine
Dosage: third maintenance cycle
Start date: 2010-09-06
Vincristine
Indication: Diffuse Large B-Cell Lymphoma
Possible Neupogen side effects in 71 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23
Patient: 71 year old female
Reactions: Breast Cancer Metastatic, Metastases To Liver, Urticaria, Metastases To Central Nervous System, Metastases To Bone, Metastases To Lung, Arthropod Bite
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupogen
Dosage: unk
Indication: Chemotherapy
Start date: 2011-01-31
End date: 2011-06-10
Xgeva
Dosage: unk
Indication: Metastases To Bone
Other drugs received by patient: Navelbine
Possible Neupogen side effects in 56 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23
Patient: 56 year old female
Reactions: Weight Decreased, White Blood Cell Count Decreased, Vomiting, Dyspnoea, Anaemia, Headache
Drug(s) suspected as cause:
Boceprevir
Dosage: 4 df, tid
Administration route: Oral
Indication: Hepatitis C
Neupogen
Dosage: unk
Indication: Product Used FOR Unknown Indication
Pegasys
Dosage: 90 mug, qwk
Pegasys
Dosage: 90 mug, qwk
Indication: Hepatitis C
Start date: 2011-12-20
Ribasphere
Dosage: 1200 mg, qd
Indication: Hepatitis C
Start date: 2011-12-20
Other drugs received by patient: Klor-CON; Ibuprofen; Furosemide; Amlodipine
Possible Neupogen side effects in 67 year old female
Reported by a physician from Netherlands on 2012-08-23
Patient: 67 year old female, weighing 46.0 kg (101.2 pounds)
Reactions: Anaemia, Circulatory Collapse
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: unk
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2011-10-05
Doxorubicin Hydrochloride
Dosage: 72 mg, unk
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2011-10-05
Neupogen
Dosage: 6 mg, unk
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2011-10-06
Prednisone TAB
Dosage: 100 mg, unk
Administration route: Oral
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2011-10-05
Rituximab
Dosage: 540 mg, unk
Indication: Diffuse Large B-Cell Lymphoma
Start date: 2011-10-06
Possible Neupogen side effects in female
Reported by a consumer/non-health professional from Canada on 2012-08-23
Patient: female
Reactions: NO Therapeutic Response
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in female
Reported by a pharmacist from United States on 2012-08-21
Patient: female
Reactions: Pain in Extremity, Gait Disturbance
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 59 year old female
Reported by a physician from United States on 2012-08-20
Patient: 59 year old female, weighing 58.9 kg (129.6 pounds)
Reactions: White Blood Cell Count Decreased, Blood Bilirubin Increased, Jaundice, Hepatic Function Abnormal, Haematuria, Alanine Aminotransferase Increased, Cystitis, Fatigue, Diarrhoea, Aspartate Aminotransferase Increased, Platelet Count Decreased, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fluconazole
Dosage: unk
Indication: Antifungal Treatment
End date: 2012-07-24
Mozobil
Dosage: unk, 2 cycles
Indication: Acute Myeloid Leukaemia
Neupogen
Dosage: unk, 2 cycles
Indication: Acute Myeloid Leukaemia
Sorafenib
Dosage: unk, 2 cycles
Indication: Acute Myeloid Leukaemia
Other drugs received by patient: Antibacterial NOS; Antivirals NOS
Possible Neupogen side effects in female
Reported by a physician from United States on 2012-08-17
Patient: female, weighing 47.6 kg (104.7 pounds)
Reactions: White Blood Cell Count Decreased, Metastases To Liver, Bone Pain
Drug(s) suspected as cause:
Neupogen
Other drugs received by patient: Herceptin; Taxotere; Carboplatin
Possible Neupogen side effects in
Reported by a physician from Hungary on 2012-08-17
Patient:
Reactions: Hypersensitivity
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 71 year old female
Reported by a physician from United States on 2012-08-17
Patient: 71 year old female
Reactions: Breast Cancer Metastatic, Urticaria, Arthropod Bite
Adverse event resulted in: death
Drug(s) suspected as cause:
Neupogen
Dosage: unk
Indication: Chemotherapy
Start date: 2011-01-31
End date: 2011-06-10
Xgeva
Dosage: unk
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Navelbine
Possible Neupogen side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: male
Reactions: Diarrhoea
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in female
Reported by a pharmacist from United States on 2012-08-16
Patient: female
Reactions: Injection Site Extravasation, Underdose
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: female
Reactions: Pain
Drug(s) suspected as cause:
Neupogen
Other drugs received by patient: Herceptin; Taxotere; Carboplatin
Possible Neupogen side effects in
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient:
Reactions: Bone Pain
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Dosage: 480 mug, unk
Indication: Product Used FOR Unknown Indication
Neupogen
Dosage: 480 mug, unk
Neupogen
Neupogen
Possible Neupogen side effects in 51 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 51 year old female, weighing 114.3 kg (251.4 pounds)
Reactions: Dyspnoea, Cough
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in
Reported by a pharmacist from United States on 2012-08-16
Patient:
Reactions: Bone Pain
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in
Reported by a pharmacist from United States on 2012-08-16
Patient:
Reactions: Incorrect Route of Drug Administration
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in male
Reported by a physician from United States on 2012-08-16
Patient: male
Reactions: Cutaneous Vasculitis
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 49 year old male
Reported by a physician from United States on 2012-08-16
Patient: 49 year old male, weighing 80.0 kg (176.0 pounds)
Reactions: Burning Sensation, Nausea, Arthralgia, Oedema Peripheral
Drug(s) suspected as cause:
Aranesp
Dosage: unk
Indication: Anaemia of Malignant Disease
Start date: 2011-08-13
Neulasta
Dosage: 6 mg, unk
Indication: Chemotherapy
Start date: 2011-08-13
Neupogen
Dosage: unk
Indication: Chemotherapy
Start date: 2011-08-15
Nplate
Dosage: 500 mug, prn
Indication: Idiopathic Thrombocytopenic Purpura
Start date: 2011-08-15
Other drugs received by patient: Gemzar; Oxycodone; Bactroban; Ondansetron; Oxaliplatin; Nystatin; Remeron; Melatonin; Restoril; Aldactone
Possible Neupogen side effects in 57 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 57 year old female
Reactions: Headache
Drug(s) suspected as cause:
Neupogen
Other drugs received by patient: Nexium; Crestor; Hydrochlorothiazide; Atenolol; Plavix
Possible Neupogen side effects in 53 year old female
Reported by a physician from United States on 2012-08-16
Patient: 53 year old female, weighing 77.1 kg (169.6 pounds)
Reactions: Drug Ineffective, Condition Aggravated
Drug(s) suspected as cause:
Enbrel
Dosage: 25 mg, 2 times/wk
Indication: Product Used FOR Unknown Indication
Neupogen
Dosage: 300 mug, unk
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Triamterene and Hydrochlorothiazide; Pepcid AC; Chromium Chloride; Drospirenone and Ethinyl Estradiol; Flaxseed OIL; Vitamin D; Minerals NOS
Possible Neupogen side effects in 25 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 25 year old female
Reactions: Neutropenia
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 56 year old female
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: 56 year old female
Reactions: Arthralgia
Drug(s) suspected as cause:
Neupogen
Other drugs received by patient: Ciprofloxacin HCL; Rifampin; Etoposide; Zofran
Possible Neupogen side effects in 23 year old female
Reported by a physician from United States on 2012-08-16
Patient: 23 year old female
Reactions: Pyrexia, Pregnancy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in
Reported by a pharmacist from United States on 2012-08-16
Patient:
Reactions: Expired Drug Administered, Drug Dispensing Error
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 50 year old male
Reported by a consumer/non-health professional from United States on 2012-08-16
Patient: 50 year old male
Reactions: Injection Site Haemorrhage, Neutropenia
Drug(s) suspected as cause:
Neupogen
Possible Neupogen side effects in 78 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 78 year old male, weighing 99.8 kg (219.5 pounds)
Reactions: Eosinophil Count Increased
Drug(s) suspected as cause:
Aranesp
Dosage: 200 mg, q2wk
Indication: Anaemia
Neupogen
Dosage: 480 mug, unk
Indication: Neutropenia
Start date: 2012-07-18
Other drugs received by patient: Vancomycin; Triamterene; Synthroid; Vancomycin; Norco; Cefepime; Questran; Florinef
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