Neulasta (Pegfilgrastim) - Hospitalization - Suspected Cause - Side Effect Reports

Possible Neulasta side effects in female

Reported by a pharmacist from Canada on 2012-08-27

Patient: female

Reactions: Intestinal Perforation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Cyclophosphamide; Doxorubicin Hydrochloride

Possible Neulasta side effects in female

Reported by a physician from Germany on 2012-08-27

Patient: female

Reactions: Drug Ineffective, Lymphopenia, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Doxorubicin Hydrochloride; Prednisone TAB; Rituximab; Vincristine; Cyclophosphamide

Possible Neulasta side effects in male

Reported by a physician from Germany on 2012-08-24

Patient: male

Reactions: Febrile Neutropenia, Skin Infection, Neutropenia, Pneumonitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1500 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Doxorubicin Hydrochloride
    Dosage: 100 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Neulasta
    Dosage: 6 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-06
    End date: 2012-04-20

Prednisolone
    Dosage: 100 mg, unk
    Administration route: Oral
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-21

Rituximab
    Dosage: 750 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-01
    End date: 2012-04-16

Vincristine
    Dosage: 2 mg, unk
    Indication: B-Cell Lymphoma
    Start date: 2012-02-02
    End date: 2012-04-17

Other drugs received by patient: MST / 00036302 /; Novalgin / 00169801 /; Rulid; Pantoprazole; Paspertin / 00041902 /; Acyclovir; Electrolytes NOS W / Macrogol 3350; Dipyrone INJ; Metoclopramide; Acyclovir

Possible Neulasta side effects in 44 year old female

Reported by a physician from Germany on 2012-08-23

Patient: 44 year old female, weighing 72.0 kg (158.4 pounds)

Reactions: Venous Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1110 mg, q3wk
    Indication: Breast Cancer
    Start date: 2010-08-03
    End date: 2010-10-05

Neulasta
    Dosage: 6 mg, qd
    Indication: Colony Stimulating Factor Prophylaxis
    Start date: 2010-10-06

Taxotere
    Dosage: 138.75 mg, q3wk
    Indication: Breast Cancer
    Start date: 2010-08-03
    End date: 2010-10-05

Other drugs received by patient: Dexamethasone Sodium Phosphate; Dexamethasone Sodium Phosphate; Palonosetron; Mesna; Bromocriptin; Dexamethasone Sodium Phosphate; Mesna

Possible Neulasta side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23

Patient: female, weighing 87.7 kg (192.9 pounds)

Reactions: Anxiety, Chest Pain, Stress

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: every 2 weeks x 3 cycles
    Start date: 2012-07-12
    End date: 2012-08-09

Gemcitabine Hydrochloride
    Dosage: every 2 weeks x 3 cycles
    Start date: 2012-07-12
    End date: 2012-08-09

Neulasta
    Dosage: day 2 of cycle x 3
    Start date: 2012-07-08
    End date: 2012-08-11

Possible Neulasta side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-08-23

Patient: 47 year old female

Reactions: Abdominal Pain, Bone Pain, Neutropenia, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Cyclophosphamide; Docetaxel

Possible Neulasta side effects in 50 year old female

Reported by a pharmacist from United Kingdom on 2012-08-23

Patient: 50 year old female

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Antineoplastic Agents; Ciprofloxacin

Possible Neulasta side effects in 50 year old female

Reported by a physician from United Kingdom on 2012-08-23

Patient: 50 year old female, weighing 68.0 kg (149.6 pounds)

Reactions: Swelling Face, Dyspnoea, Body Temperature Increased, Drug Ineffective, Neutropenic Sepsis, Anaphylactic Reaction, Swollen Tongue, Erythema, Oedema Mucosal, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Fluorouracil; Dexamethasone; Zofran; Metoclopramide; Epirubicin; Cyclophosphamide

Possible Neulasta side effects in 16 year old male

Reported by a pharmacist from Australia on 2012-08-22

Patient: 16 year old male

Reactions: LIP Swelling, Swelling Face, Anaphylactic Reaction

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Doxorubicin HCL; Vinblastine Sulfate; Dacarbazine; Bleomycin

Possible Neulasta side effects in female

Reported by a physician from Denmark on 2012-08-21

Patient: female, weighing 74.0 kg (162.8 pounds)

Reactions: Back Pain, Pulmonary Embolism

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Cyclophosphamide
    Dosage: 05/mar/2012: last dose prioe to onset of sae
    Start date: 2012-03-05

Doxorubicin HCL
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Doxorubicin HCL
    Start date: 2012-03-05

Mabthera
    Dosage: last dose prior to sae was on 13/feb/2012
    Start date: 2012-03-05

Mabthera
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Mabthera
    Start date: 2012-02-13

Neulasta
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-10
    End date: 2012-02-10

Neulasta
    Start date: 2012-02-23

Neulasta
    Start date: 2012-03-08

Prednisone TAB
    Dosage: last dose prior to sae was on 9/mar/2012
    Administration route: Oral
    Start date: 2012-03-05

Prednisone TAB
    Administration route: Oral
    Start date: 2012-02-27
    End date: 2012-02-27

Prednisone TAB
    Administration route: Oral
    Start date: 2012-02-20
    End date: 2012-02-24

Prednisone TAB
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Vincristine
    Start date: 2012-03-05

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-02-07

Other drugs received by patient: Acyclovir; Ondansetron; Tramadol HCL; Lansoprazole; Acyclovir; Lansoprazole; Bactrim

Possible Neulasta side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female

Reactions: Visual Impairment, Dizziness, Asthenia, Bladder Cancer

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Antineoplastic Agents

Possible Neulasta side effects in female

Reported by a physician from Germany on 2012-08-20

Patient: female

Reactions: Drug Ineffective, Lymphopenia, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Doxorubicin HCL; Rituximab; Prednisone TAB; Cyclophosphamide; Vincristine

Possible Neulasta side effects in 77 year old female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-08-20

Patient: 77 year old female, weighing 85.0 kg (187.0 pounds)

Reactions: Myalgia, Dyspnoea, Malaise, Palpitations, Sepsis, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Docetaxel; Doxorubicin Hydrochloride

Possible Neulasta side effects in 18 year old

Reported by a physician from Germany on 2012-08-17

Patient: 18 year old

Reactions: Abdominal Discomfort

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Adriamycin PFS
    Dosage: 35 mg/m2, unk
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: 10 mg/m2, unk
    Indication: Hodgkin's Disease

Cotrim

Cyclophosphamide
    Dosage: 1250 mg/m2, unk
    Indication: Hodgkin's Disease

Etoposide
    Dosage: 200 mg/m2, unk
    Indication: Hodgkin's Disease

Neulasta
    Dosage: 6 mg, unk
    Indication: Chemotherapy
    Start date: 2011-10-15

Prednisone TAB
    Dosage: 40 mg/m2, unk
    Indication: Hodgkin's Disease

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, unk
    Indication: Hodgkin's Disease

Vincristine
    Dosage: 1.4 mg/m2, unk
    Indication: Hodgkin's Disease

Possible Neulasta side effects in 39 year old

Reported by a physician from Germany on 2012-08-16

Patient: 39 year old

Reactions: Angina Pectoris, Bone Pain, Chest Pain, Febrile Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Bleomycin Sulfate; Diazepam; Adriamycin PFS; Procarbazine Hydrochloride; Emend; Vincristine; Etoposide; Prednisone TAB; Mesna; Levofloxacin; Cyclophosphamide; Emend

Possible Neulasta side effects in 51 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16

Patient: 51 year old male, weighing 65.4 kg (143.9 pounds)

Reactions: Pseudomonas Infection, Thrombophlebitis, Device Related Infection, Pulmonary Cavitation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Mantle Cell Lymphoma

Cytarabine
    Dosage: 5.64 g with 500 ml of 0.9 % nacl infused over 2 hours at 250 ml/hr
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-06
    End date: 2012-07-07

Dexamethasone Sodium Phosphate
    Dosage: unk
    Indication: Mantle Cell Lymphoma

Doxorubicin HCL
    Indication: Mantle Cell Lymphoma
    Start date: 2012-06-06
    End date: 2012-06-11

Doxorubicin HCL
    Start date: 2012-07-04

Fluconazole
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-04

Methotrexate
    Dosage: 1504 mg in 250 ml of nacl 0.9 % infused over 22 hours at 11.3636 ml/hr
    Start date: 2012-07-06

Methotrexate
    Dosage: 376 mg with 250 ml of 0.9 % sodium chloride, infuse over 2 hours
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05

Neulasta
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-10

Rasburicase
    Dosage: 100 ml/hr for 15 min then 100 ml/hr for 30 min then increased to 400 ml/hr
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-03

Rituximab
    Indication: Mantle Cell Lymphoma
    Start date: 2012-06-06
    End date: 2012-06-11

Rituximab
    Dosage: 375 mg/m2, unk

Velcade
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-04

Vincristine
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: RED Blood Cells; Pantoprazole; Diphenhydramine Hydrochloride; Sodium Bicarbonate; Hydrocortisone; Haloperidol; Benadryl; Acetaminophen; Mesna; Ceftazidime; Voriconazole; Acetaminophen; Xanax; Oxycodone; Vicodin; Tylenol; Zolpidem; Meperidine HCL; Acetaminophen; Valtrex; RED Blood Cells; Ondansetron; Lorazepam; Ciprofloxacin; Diphenhydramine Hydrochloride; Leucovorin Calcium; Rituxan; Meropenem; Hydrocortisone

Possible Neulasta side effects in 81 year old male

Reported by a consumer/non-health professional from United States on 2012-08-16

Patient: 81 year old male

Reactions: White Blood Cell Count Decreased, Palpitations, Platelet Count Decreased, Clostridial Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Possible Neulasta side effects in

Reported by a physician from Germany on 2012-08-15

Patient:

Reactions: Pain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Vincristine; Procarbazine Hydrochloride; Cyclophosphamide; Bleomycin; Etoposide; Adriamycin PFS; Prednisone TAB

Possible Neulasta side effects in female

Reported by a physician from United States on 2012-08-13

Patient: female, weighing 37.1 kg (81.6 pounds)

Reactions: Fatigue, Body Temperature Increased, Hypophagia, Heart Rate Increased, Oropharyngeal Pain, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1000 mg
    End date: 2012-07-27

Doxorubicin HCL
    Dosage: 100 mg
    End date: 2012-07-27

Neulasta
    Dosage: 6 mg
    End date: 2012-07-28

Possible Neulasta side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-13

Patient: 47 year old female

Reactions: Urticaria

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta
    Dosage: 3.6 mg, unk
    Indication: Chemotherapy
    Start date: 2011-06-07
    End date: 2012-06-07

Neulasta
    Dosage: 3.6 mg, unk
    Start date: 2011-06-28
    End date: 2011-06-28

Other drugs received by patient: Hachiazule; Magmitt; Fluorometholone; Cyclophosphamide; Levofloxacin; Lyrica; Taxotere; Levothyroxine Sodium; Kytril; Betamethasone Sodium Phosphate; Decadron Phosphate

Possible Neulasta side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10

Patient: male, weighing 65.4 kg (143.9 pounds)

Reactions: Pseudomonas Infection, Thrombophlebitis, Device Related Infection, Pulmonary Cavitation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Mantle Cell Lymphoma

Cytarabine
    Dosage: 5.64 g with 500 ml of 0.9% nacl infused over 2 hours at 250 ml/hr
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-06
    End date: 2012-07-07

Dexamethasone
    Indication: Mantle Cell Lymphoma

Doxorubicin Hydrochloride
    Dosage: cycle 1
    Indication: Mantle Cell Lymphoma
    Start date: 2012-06-06
    End date: 2012-06-11

Doxorubicin Hydrochloride
    Dosage: cycle 2
    Start date: 2012-07-04

Fluconazole
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-04

Methotrexate
    Dosage: 1504 mf in 250 ml of nacl 0.9% infused over 22 hours at 11.3636ml/hr
    Start date: 2012-07-06

Methotrexate
    Dosage: on day 2; 376 mg with 250 ml of 0.9% sodium chloride, infuse over 2 hours at 125 ml/hr
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-05
    End date: 2012-07-05

Neulasta
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-10

Rasburicase
    Dosage: 100 ml/hr for 15 min then 100 ml/hr for 30 min then increased to 400 ml/hr
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-03

Rituximab

Rituximab
    Indication: Mantle Cell Lymphoma
    Start date: 2012-06-06
    End date: 2012-06-11

Velcade
    Indication: Mantle Cell Lymphoma
    Start date: 2012-07-04

Vincristine
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: Tylenol; Lorazepam; Voriconazole; Diphenhydramine Hydrochloride; Zolpidem; Meperidine HCL; Ciprofloxacin; Acetaminophen; Leucovorin Calcium; Acetaminophen; Acetaminophen; Meropenem; RED Blood Cells; Diphenhydramine Hydrochloride; Sodium Bicarbonate; Hydrocortisone; Xanax; Haloperidol; Oxycodone HCL; Valtrex; Vicodin; Pantoprazole; Mesna; Benadryl; RED Blood Cells; Hydrocortisone; Ondansetron; Ceftazidime; Rituxan

Possible Neulasta side effects in 65 year old male

Reported by a consumer/non-health professional from United States on 2012-08-09

Patient: 65 year old male, weighing 75.3 kg (165.6 pounds)

Reactions: Hypocalcaemia, Pancytopenia, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Aranesp
    Dosage: unk
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-05-03

Neulasta
    Dosage: unk
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-03-30
    End date: 2011-07-20

Xgeva
    Dosage: 120 mg, one time dose
    Indication: Metastases To Bone
    Start date: 2011-07-20
    End date: 2011-07-20

Other drugs received by patient: Kytril; Alimta; Avastin; Vitamin B12 / 00056201 /; Decadron

Possible Neulasta side effects in female

Reported by a consumer/non-health professional from Ireland on 2012-08-09

Patient: female

Reactions: Pyrexia, Influenza

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Dexamethasone; Lansoprazole; Lyrica; Antineoplastic Agents; Lexapro; Valoid / 00014902 /; Zofran; Amitriptyline HCL; Emend; Motilium / 00498201 /; Mycostatin; Ativan

Possible Neulasta side effects in male

Reported by a health professional (non-physician/pharmacist) from Portugal on 2012-08-08

Patient: male

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Cisplatin; Bleomycin Sulfate; Etoposide

Possible Neulasta side effects in male

Reported by a consumer/non-health professional from Portugal on 2012-08-08

Patient: male

Reactions: Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Bleomycin Sulfate; Etoposide; Cisplatin

Possible Neulasta side effects in

Reported by a physician from Germany on 2012-08-07

Patient:

Reactions: Pain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Cyclophosphamide; Prednisone TAB; Adriamycin PFS; Bleomycin Sulfate; Procarbazine Hydrochloride; Etoposide; Vincristine

Possible Neulasta side effects in 64 year old male

Reported by a physician from Australia on 2012-08-03

Patient: 64 year old male

Reactions: Neutropenic Sepsis, Necrotising Colitis, Febrile Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Cisplatin; Immunosuppressants; Etoposide

Possible Neulasta side effects in 71 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-02

Patient: 71 year old female, weighing 74.0 kg (162.8 pounds)

Reactions: Fatigue

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 1020 mg, q3wk
    Indication: Breast Cancer
    Start date: 2009-12-09
    End date: 2010-01-27

Neulasta
    Dosage: 6 mg, q3wk
    Indication: Premedication
    Start date: 2009-12-09
    End date: 2010-01-27

Neulasta
    Indication: Colony Stimulating Factor Prophylaxis

Taxotere
    Dosage: 128 mg, q3wk
    Indication: Breast Cancer
    Start date: 2009-12-09
    End date: 2010-01-27

Other drugs received by patient: Dexamethasone; Aloxi; Mesna; Dexamethasone

Possible Neulasta side effects in 54 year old female

Reported by a physician from Australia on 2012-08-02

Patient: 54 year old female

Reactions: Pneumonia, Sepsis, Hypotension, Lactic Acidosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Neulasta
    Indication: Chemotherapy

Neulasta
    Indication: Neutropenia

Other drugs received by patient: Taxotere; Cyclophosphamide

Possible Neulasta side effects in 54 year old female

Reported by a physician from Australia on 2012-08-01

Patient: 54 year old female

Reactions: Pneumonia, Neutropenic Sepsis, Hypotension, Lactic Acidosis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Neulasta

Other drugs received by patient: Cyclophosphamide; Taxotere