Index of reports
> Cases with Hypertrophic Cardiomyopathy (11)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Myozyme (Alglucosidase Alfa) where reactions include hypertrophic cardiomyopathy. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Myozyme side effects in 2 year old female
Reported by a physician from Italy on 2012-07-17
Patient: 2 year old female
Reactions: Left Ventricular Dysfunction, Hypertrophic Cardiomyopathy, Acute Respiratory Failure, Respiratory Tract Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Myozyme
Possible Myozyme side effects in male
Reported by a physician from Germany on 2012-07-09
Patient: male, weighing 7.4 kg (16.3 pounds)
Reactions: Therapeutic Response Decreased, Hypertrophic Cardiomyopathy
Drug(s) suspected as cause:
Myozyme
Other drugs received by patient: Ergocalciferol; Spironolactone; Captopril; Lasix
Possible Myozyme side effects in
Reported by a physician from Israel on 2012-06-25
Patient:
Reactions: Death, Pneumonia, Renal Failure, Hypertrophic Cardiomyopathy, Coma, Cardiac Failure Congestive
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Myozyme
Other drugs received by patient: Deralin
Possible Myozyme side effects in male
Reported by a physician from Italy on 2012-06-22
Patient: male
Reactions: Hypertrophic Cardiomyopathy, Drug Ineffective, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Myozyme
Dosage: 13.5 mg/kg, q2w
Start date: 2011-12-05
End date: 2012-01-18
Myozyme
Dosage: 20 mg/kg, qw
Indication: Glycogen Storage Disease Type II
Start date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, unk
Start date: 2011-07-09
End date: 2011-12-05
Other drugs received by patient: Diuretics; Propranolol; Hydrocortisone; Chlorphenamine
Possible Myozyme side effects in male
Reported by a physician from Italy on 2012-06-11
Patient: male
Reactions: Drug Ineffective, Hypertrophic Cardiomyopathy, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Myozyme
Dosage: 20 mg/kg, qw
Indication: Glycogen Storage Disease Type II
Start date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, q2w
Start date: 2011-12-05
End date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, unk
Start date: 2011-07-09
End date: 2011-12-05
Other drugs received by patient: Diuretics; Chlorphenamine; Propranolol; Hydrocortisone
Possible Myozyme side effects in male
Reported by a physician from Italy on 2012-05-24
Patient: male
Reactions: Hypertrophic Cardiomyopathy, Drug Ineffective, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Myozyme
Dosage: 13.5 mg/kg, q2w
Start date: 2011-12-05
End date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, unk
Start date: 2011-07-09
End date: 2011-12-05
Myozyme
Dosage: 20 mg/kg, qw
Indication: Glycogen Storage Disease Type II
Start date: 2012-01-18
Other drugs received by patient: Rituximab; Propranolol; Chlorpheniramine TAB; Diuretics; Hydrocortisone
Possible Myozyme side effects in female
Reported by a physician from Mexico on 2012-05-07
Patient: female, weighing 4.0 kg (8.8 pounds)
Reactions: Acute Pulmonary Oedema, Cardiac Failure, Hypertrophic Cardiomyopathy, Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Myozyme
Other drugs received by patient: Captopril; Magnesium Sulfate; Furosemide; Acetaminophen; Spironolactone
Possible Myozyme side effects in female
Reported by a physician from Mexico on 2012-04-13
Patient: female, weighing 4.0 kg (8.8 pounds)
Reactions: Acute Pulmonary Oedema, Cardiac Failure, Hypertrophic Cardiomyopathy, Sepsis
Adverse event resulted in: death
Drug(s) suspected as cause:
Myozyme
Other drugs received by patient: Captopril; Acetaminophen; Magnesium Sulfate; Spironolactone; Furosemide
Possible Myozyme side effects in male
Reported by a physician from Italy on 2012-03-20
Patient: male
Reactions: Drug Ineffective, Hypertrophic Cardiomyopathy, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Myozyme
Dosage: 20 mg/kg, qw
Indication: Glycogen Storage Disease Type II
Start date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, q2w
Start date: 2011-12-05
End date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, unk
Start date: 2011-07-09
End date: 2011-12-05
Other drugs received by patient: Diuretics; Hydrocortisone; Propranolol; Chlorpheniramine Maleate
Possible Myozyme side effects in 9 month old male
Reported by a physician from Italy on 2012-03-12
Patient: 9 month old male
Reactions: Hypertrophic Cardiomyopathy, Drug Ineffective, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Myozyme
Dosage: 13.5 mg/kg, q2w
Start date: 2011-12-05
End date: 2012-01-18
Myozyme
Dosage: 20 mg/kg, qw
Indication: Glycogen Storage Disease Type II
Start date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, unk
Start date: 2011-07-09
End date: 2011-12-05
Other drugs received by patient: Diuretics; Chlorpheniramine Maleate; Hydrocortisone; Propranolol
Possible Myozyme side effects in 9 month old male
Reported by a physician from Italy on 2012-02-17
Patient: 9 month old male
Reactions: Drug Ineffective, Hypertrophic Cardiomyopathy, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Myozyme
Dosage: 13.5 mg/kg, q2w
Start date: 2011-12-05
End date: 2012-01-18
Myozyme
Dosage: 13.5 mg/kg, unk
Start date: 2011-07-09
End date: 2011-12-05
Myozyme
Dosage: 20 mg/kg, qw
Indication: Glycogen Storage Disease Type II
Start date: 2012-01-18
Other drugs received by patient: Diuretics; Hydrocortisone; Propranolol; Chlorpheniramine Maleate
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