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Index of reports
> Cases with Hypokalaemia (12)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Metolazone where reactions include hypokalaemia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Metolazone side effects in 64 year old male
Reported by a pharmacist from United States on 2012-07-30
Patient: 64 year old male, weighing 118.6 kg (260.9 pounds)
Reactions: Hyponatraemia, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bumetanide
Dosage: 2 mg bid po
Administration route: Oral
Indication: Polyuria
Start date: 2010-10-31
End date: 2012-07-24
Metolazone
Dosage: 5 mg other po
Administration route: Oral
Indication: Polyuria
Start date: 2012-07-05
End date: 2012-07-24
Possible Metolazone side effects in 64 year old female
Reported by a physician from Canada on 2012-04-10
Patient: 64 year old female
Reactions: Torsade DE Pointes, Electrocardiogram QT Prolonged, Hypomagnesaemia, Electrolyte Imbalance, Hypokalaemia
Drug(s) suspected as cause:
Amiodarone Hydrochloride
Indication: Ventricular Arrhythmia
Venlafaxine
Furosemide
Domperidone
Metolazone
Possible Metolazone side effects in 64 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-23
Patient: 64 year old female
Reactions: Torsade DE Pointes, Electrocardiogram QT Prolonged, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Amiodarone Hydrochloride
Dosage: 150mg bolus
Amiodarone Hydrochloride
Furosemide
Dosage: 40mg od
Venlafaxine
Dosage: 112.5mg od
Domperidone
Dosage: 10mg tid
Metolazone
Dosage: 2.5mg od
Other drugs received by patient: Glyburide; Omeprazole; Levothyroxine Sodium; Irbesartan; Digoxin; Metformin HCL; Lipitor
Possible Metolazone side effects in 64 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-23
Patient: 64 year old female
Reactions: Torsade DE Pointes, Electrocardiogram QT Prolonged, Road Traffic Accident, Hypomagnesaemia, Atrial Fibrillation, Loss of Consciousness, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Furosemide
Dosage: 40mg od
Domperidone
Dosage: 10mg tid
Amiodarone Hydrochloride
Dosage: 150mg bolus
Metolazone
Dosage: 2.5mg od
Venlafaxine
Dosage: 112.5mg od
Amiodarone Hydrochloride
Other drugs received by patient: Irbesartan; Digoxin; Lipitor; Metformin HCL; Levothyroxine Sodium; Omeprazole; Glyburide
Possible Metolazone side effects in 64 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-23
Patient: 64 year old female
Reactions: Electrocardiogram QT Prolonged, Torsade DE Pointes, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Domperidone
Dosage: 10mg tid
Metolazone
Dosage: 2.5mg od
Venlafaxine
Dosage: 112.5mg od
Amiodarone Hydrochloride
Dosage: 150mg bolus
Amiodarone Hydrochloride
Furosemide
Dosage: 40mg od
Other drugs received by patient: Omeprazole; Metformin HCL; Glyburide; Lipitor; Levothyroxine Sodium; Digoxin; Irbesartan
Possible Metolazone side effects in 64 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-23
Patient: 64 year old female
Reactions: Torsade DE Pointes, Electrocardiogram QT Prolonged, Road Traffic Accident, Hypomagnesaemia, Atrial Fibrillation, Loss of Consciousness, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Venlafaxine
Dosage: 112.5mg od
Amiodarone Hydrochloride
Domperidone
Dosage: 10mg tid
Amiodarone Hydrochloride
Dosage: 150mg bolus
Furosemide
Dosage: 40mg od
Metolazone
Dosage: 2.5mg od
Other drugs received by patient: Omeprazole; Metformin HCL; Lipitor; Irbesartan; Levothyroxine Sodium; Digoxin; Glyburide
Possible Metolazone side effects in 64 year old female
Reported by a health professional (non-physician/pharmacist) from Canada on 2012-03-22
Patient: 64 year old female
Reactions: Electrocardiogram QT Prolonged, Tachycardia, Atrial Fibrillation, Hypokalaemia, Torsade DE Pointes, Syncope, Hypomagnesaemia, Dizziness
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Amiodarone Hydrochloride
Venlafaxine
Dosage: 112.5 mg, qd
Furosemide
Dosage: 40 mg, qd
Domperidone
Dosage: 10 mg, tid
Metolazone
Dosage: 2.5 mg, qd
Amiodarone Hydrochloride
Dosage: 150 mg, unk
Other drugs received by patient: Digoxin; Atorvastatin; Irbesartan; Citalopram Hydrobromide; Metformin HCL; Glyburide; Levothyroxine Sodium; Omeprazole
Possible Metolazone side effects in 87 year old female
Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-02-23
Patient: 87 year old female
Reactions: Hyponatraemia, Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Torsemide
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-01
Torsemide
Administration route: Oral
End date: 2011-12-24
Metolazone
Administration route: Oral
Indication: Cardiac Failure
Start date: 2011-12-01
End date: 2011-12-24
Other drugs received by patient: Atrovent; Lansoprazole; Pulmicort-100; Actonel; Ventolin; Tenormin
Possible Metolazone side effects in 58 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-26
Patient: 58 year old male, weighing 162.4 kg (357.3 pounds)
Reactions: Hypokalaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Celecoxib;ibuprofen / Naproxen; Placebo (Investigational Drug)
Dosage: oral
Administration route: Oral
Indication: Osteoarthritis
Start date: 2010-09-28
Metolazone
Dosage: oral
Administration route: Oral
Start date: 2011-03-04
End date: 2011-03-15
Other drugs received by patient: Nexium; Furosemide; Spironolactone; Carvedilol; Pravastatin
Possible Metolazone side effects in 90 year old female
Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-01-12
Patient: 90 year old female
Reactions: Dehydration, Condition Aggravated, General Physical Health Deterioration, Asthenia, Renal Failure Chronic, Hypokalaemia, Alkalosis
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Metolazone
Dosage: 5 mg (5 mg, 1 in 1 d), oral
Administration route: Oral
Indication: Renal Failure Chronic
End date: 2011-11-16
Torsemide
Dosage: 150 mg (150 mg, 1 in 1 d), oral
Administration route: Oral
Indication: Renal Failure Chronic
End date: 2011-11-16
Possible Metolazone side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-29
Patient: male, weighing 93.0 kg (204.6 pounds)
Reactions: Cardiac Failure Chronic, Coronary Artery Disease, Concomitant Disease Progression, Hypokalaemia, Disease Progression, Ventricular Tachycardia, Hypomagnesaemia, Thrombocytopenia, Hepatic Cirrhosis, Shock
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Enalapril Maleate
Dosage: code not broken
Administration route: Oral
Indication: Cardiac Failure Chronic
End date: 2011-05-01
Metolazone
Dosage: 5 mg, every 10 days
Indication: Cardiac Failure Congestive
Start date: 2011-10-07
Furosemide
Dosage: 80 mg qam and 40 mg qpm
Indication: Cardiac Failure Congestive
Start date: 2006-01-01
Blinded NO Treatment Received
Dosage: code not broken
Administration route: Oral
Indication: Cardiac Failure Chronic
End date: 2011-05-01
Valsartan
Dosage: code not broken
Administration route: Oral
Indication: Cardiac Failure Chronic
End date: 2011-05-01
Other drugs received by patient: Aspirin; Carvedilol; Micardis; Niaspan; Crestor; Micardis
Possible Metolazone side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-23
Patient: male, weighing 108.8 kg (239.4 pounds)
Reactions: Cardiac Failure Chronic, Ventricular Tachycardia, Hypomagnesaemia, Coronary Artery Disease, Concomitant Disease Progression, Hypokalaemia, Disease Progression
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Furosemide
Dosage: 80 mg qam and 40 mg qpm
Indication: Cardiac Failure Congestive
Start date: 2006-01-01
Metolazone
Dosage: 5 mg every 10 drop
Indication: Cardiac Failure Congestive
Start date: 2011-10-07
Enalapril Maleate
Dosage: code not broken
Administration route: Oral
Indication: Cardiac Failure Chronic
End date: 2011-05-01
Potassium Supplements
Blinded NO Treatment Received
Dosage: code not broken
Administration route: Oral
Indication: Cardiac Failure Chronic
End date: 2011-05-01
Valsartan
Dosage: code not broken
Administration route: Oral
Indication: Cardiac Failure Chronic
End date: 2011-05-01
Other drugs received by patient: Crestor; Micardis; Niaspan; Micardis; Carvedilol; Aspirin
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