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Methotrexate (Methotrexate) - Disability - Suspected Cause - Side Effect Reports

 
 



Index of reports > Disability (141)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate disability. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 141   Next >>

Possible Methotrexate side effects in female

Reported by a physician from France on 2012-08-14

Patient: female

Reactions: Arthralgia, Bone Fissure, Tibia Fracture

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Actonel
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2002-06-04
    End date: 2010-06-14

Cytotec
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 1998-12-01

Enbrel
    Indication: Rheumatoid Arthritis
    Start date: 2008-05-01
    End date: 2008-10-01

Humira 40 MG / 0.8 ML PRE-Filled Syringe
    Indication: Rheumatoid Arthritis
    Start date: 2008-10-01
    End date: 2009-03-01

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-02-05

Orencia
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-01

Pentasa
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-01-01

Plaquenil
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1994-12-01

Prednisone TAB
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1995-02-20

Prednisone TAB
    Administration route: Oral
    Start date: 1995-02-20

Protelos
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2011-02-18
    End date: 2011-09-13



Possible Methotrexate side effects in female

Reported by a physician from Germany on 2012-08-10

Patient: female

Reactions: Cellulitis, C-Reactive Protein Increased, Necrosis, Lymphangitis, Aplastic Anaemia, Skin Necrosis, Empyema, Thermal Burn, White Blood Cell Count Increased

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2005-12-01
    End date: 2006-12-01

Hydrocortisone
    Indication: Rheumatoid Arthritis

Methotrexate
    Administration route: Oral
    Start date: 2007-06-19

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2005-12-01
    End date: 2006-12-01

Other drugs received by patient: Prednisolone; Etanercept



Possible Methotrexate side effects in 79 year old female

Reported by a consumer/non-health professional from Colombia on 2012-08-02

Patient: 79 year old female

Reactions: Blood Pressure Increased, Drug Ineffective, Urinary Tract Infection, Varicophlebitis, Headache, Gastritis, Transaminases Abnormal, Gait Disturbance, Arthritis

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2009-10-01
    End date: 2009-12-01

Enbrel
    Dosage: 50 mg, weekly
    Start date: 2010-07-01
    End date: 2010-09-01

Methotrexate
    Dosage: unknown
    Administration route: Oral
    Indication: Arthritis
    Start date: 2000-01-01

Olmesartan Medoxomil and Hydrochlorothizide
    Dosage: 40/12.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2006-01-01

Other drugs received by patient: Prednisolone; Prednisolone



Possible Methotrexate side effects in female

Reported by a physician from France on 2012-08-01

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Diverticulitis, Lymphopenia, Pulmonary Embolism, Cytomegalovirus Colitis, Peritonitis, Intestinal Perforation, Diffuse Large B-Cell Lymphoma, Lymphoma

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis

Etanercept
    Indication: Rheumatoid Arthritis

Mabthera
    Indication: Rheumatoid Arthritis

Methotrexate
    Indication: Rheumatoid Arthritis

Piroxicam
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Omeprazole; Ferrous Sulfate TAB; Vitamin D; Indapamide; Protelos; Aluminum Hydroxide and Magnesium Trisilicate; Calcium Carbonate; Prednisone TAB; Imodium; Folic Acid; Arixtra; Acetaminophen



Possible Methotrexate side effects in 10 year old female

Reported by a physician from India on 2012-07-27

Patient: 10 year old female

Reactions: Endophthalmitis, Corneal Perforation, Atrophy of Globe, Keratitis Bacterial, Streptococcus Test Positive

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Chloramphenicol 0.5 %eye Drops (Chloramphenicol 0.5%) (None)
    Dosage: (0.5 % qid ophthalmic)
    Indication: Ulcerative Keratitis

Methotrexate
    Dosage: (7.5-12.5 mg/week oral)
    Administration route: Oral
    Indication: Ulcerative Keratitis

Methylprednisolone
    Dosage: (500 mg qd 3 days until intravenous (not otherwise specified)
    Indication: Ulcerative Keratitis

Prednisolone Acetate
    Dosage: (1 % q1h ophthalmic), (tapered according to treatment response ophthalmic)
    Indication: Ulcerative Keratitis

Other drugs received by patient: Folic Acid; Atropine Sulfate



Possible Methotrexate side effects in 77 year old female

Reported by a consumer/non-health professional from Colombia on 2012-07-25

Patient: 77 year old female

Reactions: Feeling of Despair, Blood Pressure Increased, Urinary Tract Infection, Condition Aggravated, Varicose Vein, Headache, Transaminases Abnormal, Gastritis, Therapy Cessation, Gait Disturbance, Arthritis, Inflammation

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: (50 mg,q weekly),per oral ; (50 mg,q weekly),per oral
    Administration route: Oral
    Indication: Arthritis
    Start date: 2009-10-01
    End date: 2009-12-01

Enbrel
    Dosage: (50 mg,q weekly),per oral ; (50 mg,q weekly),per oral
    Administration route: Oral
    Indication: Arthritis
    Start date: 2010-07-01
    End date: 2010-09-01

Methotrexate
    Dosage: per oral
    Administration route: Oral
    Indication: Arthritis
    Start date: 2000-01-01
    End date: 2009-10-01

Olmesartan Medoxomil and Hydrochlorothizide
    Dosage: 40/12.5 mg (qd),per oral
    Administration route: Oral
    Indication: Hypertension
    Start date: 2006-01-01

Vasoton (Aesculus Hippocastanum) (Tablet) (Aesculus Hippocastanum)
    Dosage: (300 mg),per oral
    Administration route: Oral
    Indication: Varicose Vein
    Start date: 2010-07-01
    End date: 2010-07-01

Other drugs received by patient: Prednisolone (Prednisolone) (Tablet) (Prednisolone); Omeprazole; Ranitidine



Possible Methotrexate side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-24

Patient: 58 year old female

Reactions: Sudden Hearing Loss, Deafness Unilateral, Deafness Neurosensory

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Humira
    Dosage: 40 mg milligram(s), 2 week, subcutaneous
    Indication: Rheumatoid Arthritis

Hydroxychloroquine Sulfate
    Dosage: 200 mg milligram(s), 1 day, oral
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Methotrexate
    Dosage: 22.5 mg milligram(s), 1 week,
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Fluticasone Propionate; Alendronate Sodium



Possible Methotrexate side effects in 79 year old female

Reported by a consumer/non-health professional from Colombia on 2012-07-20

Patient: 79 year old female

Reactions: Blood Pressure Increased, Drug Ineffective, Urinary Tract Infection, Varicophlebitis, Headache, Transaminases Abnormal, Gastritis, Gait Disturbance, Arthritis

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2009-10-01
    End date: 2009-12-01

Enbrel
    Dosage: 50 mg, weekly
    Start date: 2010-07-01
    End date: 2010-09-01

Methotrexate
    Dosage: unknown
    Administration route: Oral
    Indication: Arthritis
    Start date: 2000-01-01

Olmesartan Medoxomil and Hydrochlorothizide
    Dosage: 40/12.5 mg, 1x/day
    Indication: Hypertension
    Start date: 2006-01-01

Other drugs received by patient: Prednisolone; Prednisolone



Possible Methotrexate side effects in male

Reported by a physician from Denmark on 2012-07-20

Patient: male

Reactions: Cataract, Glaucoma, AGE-Related Macular Degeneration

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Folininsyre



Possible Methotrexate side effects in 63 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-19

Patient: 63 year old female

Reactions: Bone Fissure

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Actonel
    Dosage: 35 mg, unk
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2002-06-04
    End date: 2010-06-14

Cytotec
    Dosage: unk
    Administration route: Oral
    Start date: 1998-12-01

Enbrel
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2008-05-01
    End date: 2008-10-01

Humira
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2008-10-01
    End date: 2009-03-01

Methotrexate
    Dosage: 7.5 mg, weekly
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-02-05

Orencia
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-01

Pentasa
    Dosage: unk
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-01-01

Plaquenil
    Dosage: 400 mg, 1x/day
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1994-12-01

Prednisone TAB
    Dosage: 8 mg, 1x/day
    Administration route: Oral
    Start date: 1995-02-20

Prednisone TAB
    Dosage: 5 mg, 1x/day
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1995-02-20

Protelos
    Dosage: unk
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2011-02-18
    End date: 2011-09-13



Possible Methotrexate side effects in 62 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-19

Patient: 62 year old male, weighing 48.3 kg (106.3 pounds)

Reactions: Abdominal Pain, Diarrhoea

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Folic Acid; Ramipril; Metformin Hydrochloride; Amlodipine; Simvastatin



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-18

Patient: female, weighing 97.1 kg (213.6 pounds)

Reactions: Interstitial Lung Disease

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 63 year old female

Reported by a consumer/non-health professional from France on 2012-07-18

Patient: 63 year old female

Reactions: Bone Fissure

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Actonel
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2002-06-04
    End date: 2010-06-14

Cytotec
    Administration route: Oral
    Start date: 1998-12-01

Enbrel
    Start date: 2008-05-01
    End date: 2008-10-01

Humira
    Start date: 2008-10-01
    End date: 2009-03-01

Methotrexate
    Administration route: Oral
    Start date: 1996-02-05

Orencia
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-01

Pentasa
    Administration route: Oral
    Start date: 1996-01-01

Plaquenil
    Administration route: Oral
    Start date: 1994-12-01

Prednisone TAB
    Dosage: also taken 8mg
    Administration route: Oral
    Start date: 1995-02-20

Protelos
    Indication: Osteoporosis
    Start date: 2011-02-18
    End date: 2011-09-13



Possible Methotrexate side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-18

Patient: 58 year old female

Reactions: Sudden Hearing Loss, Deafness Unilateral, Deafness Neurosensory

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2006-01-01

Hydroxychloroquine Sulfate
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Methotrexate
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Alendronate Sodium; Fluticasone Propionate



Possible Methotrexate side effects in 58 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-18

Patient: 58 year old female

Reactions: Deafness Unilateral, Deafness Neurosensory

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Humira
    Dosage: 40 mg, qw2
    Indication: Rheumatoid Arthritis
    Start date: 2006-01-01

Hydroxychloroquine Sulfate
    Dosage: 200 mg, qd
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Methotrexate
    Dosage: 22.5 mg, qw
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Fluticasone Propionate; Alendronate Sodium



Possible Methotrexate side effects in female

Reported by a physician from France on 2012-07-18

Patient: female

Reactions: Bone Fissure, Tibia Fracture

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Actonel
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2002-06-04
    End date: 2010-06-14

Cytotec
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 1998-12-01

Enbrel
    Indication: Rheumatoid Arthritis
    Start date: 2008-05-01
    End date: 2008-10-01

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2008-10-01
    End date: 2009-03-01

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-02-05

Orencia
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-01

Pentasa
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-01-01

Plaquenil
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1994-12-01

Prednisone TAB
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1995-02-20

Prednisone TAB
    Administration route: Oral
    Start date: 1995-02-20

Protelos
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2011-02-18
    End date: 2011-09-13



Possible Methotrexate side effects in 63 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-17

Patient: 63 year old female

Reactions: Bone Fissure

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Actonel
    Dosage: 35 mg, unk
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2002-06-04
    End date: 2010-06-14

Cytotec
    Dosage: unk
    Administration route: Oral
    Start date: 1998-12-01

Enbrel
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2008-05-01
    End date: 2008-10-01

Humira
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2008-10-01
    End date: 2009-03-01

Methotrexate
    Dosage: 7.5 mg, weekly
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-02-05

Orencia
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-01

Pentasa
    Dosage: unk
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-01-01

Plaquenil
    Dosage: 400 mg, 1x/day
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1994-12-01

Prednisone TAB
    Dosage: 8 mg, 1x/day
    Administration route: Oral
    Start date: 1995-02-20

Prednisone TAB
    Dosage: 5 mg, 1x/day
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1995-02-20

Protelos
    Dosage: unk
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2011-02-18
    End date: 2011-09-13



Possible Methotrexate side effects in 63 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-17

Patient: 63 year old female

Reactions: Bone Fissure

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Actonel
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2002-06-04
    End date: 2010-06-14

Cytotec
    Administration route: Oral
    Start date: 1998-12-01

Etanercept
    Indication: Rheumatoid Arthritis
    Start date: 1998-05-01
    End date: 1998-10-01

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2008-10-01
    End date: 2009-03-01

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-02-05

Orencia
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-01

Pentasa
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1996-01-01

Plaquenil
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1994-12-01

Prednisone TAB
    Administration route: Oral
    Start date: 1995-02-20

Prednisone TAB
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 1995-02-20

Strontium Ranelate
    Administration route: Oral
    Indication: Osteoporosis
    Start date: 2011-02-18
    End date: 2011-09-13



Possible Methotrexate side effects in 50 year old female

Reported by a consumer/non-health professional from Norway on 2012-07-06

Patient: 50 year old female, weighing 59.0 kg (129.8 pounds)

Reactions: Neuropathy Peripheral

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-21

Orencia
    Dosage: 10feb2009,24feb2009
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-27
    End date: 2010-08-01

Orencia
    Dosage: 10feb2009,24feb2009
    Indication: Gout
    Start date: 2009-01-27
    End date: 2010-08-01

Other drugs received by patient: Prednisolone; Folic Acid



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-07-06

Patient: female, weighing 2.5 kg (5.4 pounds)

Reactions: Oligohydramnios, Congenital Hand Malformation, Maternal Exposure During Pregnancy, HIP Dysplasia, Conus Medullaris Syndrome, Congenital JAW Malformation, Congenital Joint Malformation, Small FOR Dates Baby, Synostosis, Congenital Anomaly, Hydrocephalus

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate
    Dosage: 50mg/m2, intramuscularly
    Indication: Abortion Induced

Misoprostol
    Dosage: 400 mcg, oral
    Administration route: Oral
    Indication: Abortion Induced



Possible Methotrexate side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-05

Patient: 36 year old female

Reactions: Rhabdomyolysis, Disseminated Intravascular Coagulation, Arterial Thrombosis Limb, Tonsillitis, Rheumatoid Arthritis, Multi-Organ Failure, Intracardiac Thrombus, Septic Shock, Influenza

Adverse event resulted in: death, life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, unk
    Indication: Rheumatoid Arthritis
    Start date: 2011-01-31
    End date: 2012-01-25

Methotrexate
    Dosage: 20 mg, weekly
    Administration route: Oral
    Start date: 2010-10-01

Other drugs received by patient: Folic Acid; Hydrocortisone



Possible Methotrexate side effects in 67 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-05

Patient: 67 year old female

Reactions: Cataract, Neuropathy Peripheral, Neutropenia

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate
    Dosage: 3500 mg/m2
    Indication: Lymphoma

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, 1 in 1 d
    Indication: Lymphoma

Rituximab (Rituximab) (Rituximab)
    Dosage: 375 mg/m2
    Indication: Lymphoma

Vincristine
    Dosage: 1.4 mg/m2
    Indication: Lymphoma



Possible Methotrexate side effects in 60 year old female

Reported by a physician from France on 2012-06-26

Patient: 60 year old female

Reactions: Progressive Multifocal Leukoencephalopathy, Lymphocyte Count Decreased

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01
    End date: 2009-11-01

Remicade
    Indication: Rheumatoid Arthritis
    Start date: 2003-01-01
    End date: 2009-06-01

Other drugs received by patient: Acetaminophen and Tramadol HCL; Ketoprofen; Lexomil; Nexium



Possible Methotrexate side effects in 72 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-26

Patient: 72 year old male

Reactions: Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Prednisone TAB
    Indication: Rheumatoid Arthritis

Remicade
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in 41 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-25

Patient: 41 year old female

Reactions: Drug Ineffective, Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Infliximab
    Indication: Dermatomyositis
    Start date: 2008-03-13
    End date: 2008-08-21

Methotrexate
    Indication: Dermatomyositis
    Start date: 2006-06-01

Prednisone TAB
    Administration route: Oral
    Indication: Dermatomyositis
    Start date: 2006-05-01

Rituxan
    Dosage: on days 1 and 15
    Start date: 2008-10-13

Rituxan
    Indication: Dermatomyositis
    Start date: 2009-08-13

Rituxan
    Dosage: this was the last dose prior to sae onset lot numbers for this dose was 720648, 720649.
    Start date: 2008-10-27

Rituxan
    Dosage: one days 1 and 15
    Start date: 2007-07-01

Other drugs received by patient: Tramadol Hydrochl; Hydrochlorothiazide; Actonel; Folic Acid



Possible Methotrexate side effects in female

Reported by a individual with unspecified qualification from France on 2012-06-25

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Lymphopenia, Diverticulitis, Pulmonary Embolism, Cytomegalovirus Colitis, Peritonitis, Intestinal Perforation, Lymphoma, Diffuse Large B-Cell Lymphoma

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis

Etanercept
    Indication: Rheumatoid Arthritis

Mabthera
    Indication: Rheumatoid Arthritis

Methotrexate
    Indication: Rheumatoid Arthritis

Piroxicam
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Acetaminophen; Ferrous Sulfate TAB; Folic Acid; Indapamide; Aluminum Hydroxide and Magnesium Trisilicate; Omeprazole; Calcium Carbonate; Prednisone TAB; Vitamin D; Arixtra; Protelos; Imodium



Possible Methotrexate side effects in 62 year old

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-25

Patient: 62 year old , weighing 48.3 kg (106.3 pounds)

Reactions: Abdominal Pain, Diarrhoea

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Folic Acid; Metformin HCL; Simvastatin; Ramipril; Amlodipine



Possible Methotrexate side effects in 72 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-22

Patient: 72 year old male

Reactions: Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Prednisone TAB
    Indication: Rheumatoid Arthritis

Remicade
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Germany on 2012-06-20

Patient: female, weighing 79.0 kg (173.8 pounds)

Reactions: Cervical Vertebral Fracture, Spinal Fracture, Diabetes Mellitus, Fall, Amenorrhoea, Hypothyroidism, Circulatory Collapse, RIB Fracture

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-15

Patient: 36 year old female

Reactions: Rhabdomyolysis, Disseminated Intravascular Coagulation, Arterial Thrombosis Limb, Tonsillitis, Rheumatoid Arthritis, Multi-Organ Failure, Septic Shock, Intracardiac Thrombus, Influenza

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, unk
    Indication: Rheumatoid Arthritis
    Start date: 2011-01-31
    End date: 2012-01-25

Methotrexate
    Dosage: 20 mg, weekly
    Administration route: Oral
    Start date: 2010-10-01

Other drugs received by patient: Folic Acid; Hydrocortisone



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