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Methotrexate (Methotrexate) - Neutropenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Neutropenia (111)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 111   Next >>

Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-08-20

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Hyperpyrexia, Anaphylactic Reaction, Chills, Pain, Hepatic Failure, Transaminases Increased, Splenic Infarction, Loss of Consciousness, Aortic Thrombosis, Off Label Use, Malaise, C-Reactive Protein Increased, Myositis, Dyspnoea, Hypotension, Arrhythmia, Lung Consolidation, Hypophosphataemia, Zygomycosis, Bacteraemia, Ventricular Tachycardia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Vincristine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Decadron Phosphate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Velcade
    Dosage: day 1, 4, 8 and 11
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Cytarabine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Methotrexate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

PEG-Asparaginase
    Dosage: day 2, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25
    End date: 2007-10-25

Doxil
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-08-16

Patient: female

Reactions: Colitis, Neutropenia

Drug(s) suspected as cause:
Mabthera
    Dosage: given after 1 month from the event
    Indication: Wegener's Granulomatosis
    Start date: 2006-11-01

Cellcept
    Indication: Wegener's Granulomatosis

Cyclophosphamide
    Indication: Wegener's Granulomatosis

Tacrolimus
    Indication: Wegener's Granulomatosis

Everolimus
    Indication: Wegener's Granulomatosis

Methotrexate
    Indication: Wegener's Granulomatosis

Immune Globulin NOS
    Indication: Wegener's Granulomatosis

Azathioprine Sodium
    Indication: Wegener's Granulomatosis

Mabthera
    Indication: Rheumatoid Arthritis
    Start date: 2006-11-01

Methotrexate
    Indication: Off Label Use

Other drugs received by patient: Prednisolone



Possible Methotrexate side effects in male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-08-15

Patient: male

Reactions: Neutropenia

Drug(s) suspected as cause:
Mabthera
    Indication: Rheumatoid Arthritis
    Start date: 2007-03-01

Methotrexate
    Indication: Truss User

Immune Globulin Intravenous (Human)
    Indication: Wegener's Granulomatosis

Azathioprine Sodium
    Indication: Wegener's Granulomatosis

Mabthera
    Dosage: given after 2 months from the event
    Indication: Wegener's Granulomatosis

Immune Globulin Intravenous (Human)
    Indication: Hypogammaglobulinaemia

Methotrexate
    Indication: Wegener's Granulomatosis

Cyclophosphamide
    Indication: Wegener's Granulomatosis

Cyclophosphamide
    Indication: Pancytopenia

Other drugs received by patient: Prednisolone



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-08-15

Patient: female

Reactions: Neutropenia

Drug(s) suspected as cause:
Mabthera
    Indication: Rheumatoid Arthritis
    Start date: 2010-03-01

Methotrexate
    Indication: Leukocytoclastic Vasculitis

Cyclosporine
    Indication: Leukopenia

Cyclosporine
    Indication: Leukocytoclastic Vasculitis

Azathioprine Sodium
    Indication: Cryoglobulinaemia

Mabthera
    Dosage: given after 2 months from the event
    Indication: Cryoglobulinaemia

Methotrexate
    Indication: Off Label Use

Methotrexate
    Indication: Cryoglobulinaemia

Azathioprine Sodium
    Indication: Leukocytoclastic Vasculitis

Cyclosporine
    Indication: Cryoglobulinaemia

Other drugs received by patient: Prednisolone



Possible Methotrexate side effects in 65 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-14

Patient: 65 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Weight Decreased, Vomiting, Mycobacterium Chelonae Infection, Hyperkalaemia, Hypercreatininaemia, Rectal Haemorrhage, Reticulocyte Count Decreased, Diarrhoea, RED Blood Cell Count Decreased, Megakaryocytes Abnormal, Neutropenia, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisone TAB
    Dosage: 3 mg, daily
    Administration route: Oral
    Indication: Juvenile Arthritis

Zyvox
    Dosage: 7.8 mg/l, unknown
    Start date: 2012-06-28

Methotrexate
    Dosage: 20 mg, weekly
    Administration route: Oral
    Indication: Juvenile Arthritis

Zyvox
    Dosage: 600 mg, 2x/day
    Start date: 2012-05-31
    End date: 2012-06-26

Ketoprofen
    Dosage: 100-300 mg, daily
    Administration route: Oral
    Indication: Juvenile Arthritis

Clarithromycin
    Dosage: 500 mg, 2x/day
    Start date: 2012-05-31
    End date: 2012-06-26

Other drugs received by patient: Sertraline; Bisoprolol; Metformin; Tetrazepam; Pantoprazole; Aspegic 1000



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-08

Patient: female

Reactions: Anaemia, Concomitant Disease Aggravated, Dermatomyositis, Neutropenia, Trichiniasis, Thrombocytopenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neoral
    Dosage: 150 mg, bid
    Administration route: Oral
    Start date: 2010-06-01
    End date: 2012-06-26

Methotrexate
    Dosage: 10 mg, qw
    Administration route: Oral
    Start date: 2011-06-01
    End date: 2012-06-26

Other drugs received by patient: Methotrexate Sodium; Folic Acid; Cortisone Acetate



Possible Methotrexate side effects in 57 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-07

Patient: 57 year old female

Reactions: Vaginal Ulceration, Renal Failure, Vulval Ulceration, C-Reactive Protein Increased, Genital Ulceration, Neutropenia, Inflammation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Naproxen
    Dosage: 550 mg daily intermittently
    Administration route: Oral
    Start date: 2002-01-01
    End date: 2012-05-25

Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2010-09-28
    End date: 2012-04-01

Methotrexate
    Dosage: 15 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-01
    End date: 2012-05-28

Folic Acid
    Dosage: unk
    Administration route: Oral
    Start date: 2002-01-01
    End date: 2012-05-25

Lamaline / 00764901 /
    Dosage: unk
    Administration route: Oral
    Start date: 2012-05-17
    End date: 2012-05-25



Possible Methotrexate side effects in 23 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-06

Patient: 23 year old female, weighing 60.0 kg (132.0 pounds)

Reactions: Abdominal Pain, Chills, Tachycardia, Anaemia, Pyrexia, Tremor, Malaise, Feeling Hot, Hypocalcaemia, Neutropenia, Blood Pressure Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin

Methotrexate

Doxorubicin HCL

Mepact
    Dosage: 3.4 mg, unk



Possible Methotrexate side effects in 35 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-03

Patient: 35 year old female

Reactions: Bone Marrow Transplant Rejection, Pneumonia Bacterial, Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Methotrexate
    Indication: Prophylaxis Against Graft Versus Host Disease

Other drugs received by patient: Antibiotics; Cytarabine; Busulfan; Fludarabine Phosphate; Acyclovir; Immune Globulin NOS



Possible Methotrexate side effects in 57 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-03

Patient: 57 year old female

Reactions: C-Reactive Protein Increased, Genital Ulceration, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 15 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-01
    End date: 2012-05-28

Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2010-09-28
    End date: 2012-04-01

Methotrexate
    Dosage: 15 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-01
    End date: 2012-05-28

Other drugs received by patient: Folic Acid; Naproxen; Lamaline / 00764901 /



Possible Methotrexate side effects in female

Reported by a physician from France on 2012-07-30

Patient: female

Reactions: Genital Ulceration, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: reported as lmeth
    Indication: Rheumatoid Arthritis
    End date: 2012-05-28

Enbrel
    Indication: Rheumatoid Arthritis
    Start date: 2010-09-28
    End date: 2012-04-01

Folic Acid
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2002-01-01
    End date: 2012-05-25

Lamaline
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-05-17
    End date: 2012-05-25

Naproxen
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2002-01-01
    End date: 2012-05-25



Possible Methotrexate side effects in male

Reported by a individual with unspecified qualification from United States on 2012-07-30

Patient: male, weighing 15.6 kg (34.3 pounds)

Reactions: Neutropenia, Pyrexia

Drug(s) suspected as cause:
PEG-L-Asparaginase (Pegaspargase, Oncospar)
    Dosage: 1597.5 mg
    End date: 2012-07-16

Vincristine Sulfate
    Dosage: 2.85 mg
    End date: 2012-07-26

Dexamethasone
    Dosage: 42 mg
    End date: 2012-07-25

Methotrexate
    Dosage: 24 mg
    End date: 2012-07-24

Daunorubicin HCL
    Dosage: 47.25 mg
    End date: 2012-07-26



Possible Methotrexate side effects in 35 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-19

Patient: 35 year old female

Reactions: Bone Marrow Transplant Rejection, Pneumonia Bacterial, Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclosporine
    Indication: Prophylaxis Against Graft Versus Host Disease

Methotrexate
    Indication: Prophylaxis Against Graft Versus Host Disease

Other drugs received by patient: Fludarabine Phosphate; Busulfan; Antibiotics; Acyclovir; Cytarabine; Immune Globulin NOS



Possible Methotrexate side effects in 43 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-05

Patient: 43 year old male

Reactions: Conjunctivitis, Neutropenia

Drug(s) suspected as cause:
Methotrexate
    Dosage: 3500 mg/m2 :400 ug, intravitreous, every two months
    Indication: Lymphoma

Rituximab (Rituximab) (Rituximab)
    Dosage: 375 mg/m2
    Indication: Lymphoma

Vincristine
    Dosage: 1.4 mg/m2
    Indication: Lymphoma

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, 1 in 1 d
    Indication: Lymphoma



Possible Methotrexate side effects in 67 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-05

Patient: 67 year old female

Reactions: Cataract, Neuropathy Peripheral, Neutropenia

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Methotrexate
    Dosage: 3500 mg/m2
    Indication: Lymphoma

Rituximab (Rituximab) (Rituximab)
    Dosage: 375 mg/m2
    Indication: Lymphoma

Vincristine
    Dosage: 1.4 mg/m2
    Indication: Lymphoma

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, 1 in 1 d
    Indication: Lymphoma



Possible Methotrexate side effects in 72 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-05

Patient: 72 year old female

Reactions: Neutropenia, Keratitis

Drug(s) suspected as cause:
Vincristine
    Dosage: 1.4 mg/m2
    Indication: Lymphoma

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, 1 in 1 d
    Indication: Lymphoma

Methotrexate
    Dosage: 3500 mg/m2, 400 ug, intravitreous, for 2 months
    Indication: Lymphoma

Rituximab (Rituximab) (Rituximab)
    Dosage: 375 mg/m2
    Indication: Lymphoma



Possible Methotrexate side effects in

Reported by a individual with unspecified qualification from United States on 2012-07-02

Patient:

Reactions: Neutropenia

Drug(s) suspected as cause:
Etoposide
    Indication: T-Cell Lymphoma Stage IV

Dexamethasone TAB
    Indication: T-Cell Lymphoma Stage IV

Methotrexate
    Indication: T-Cell Lymphoma Stage IV

Elspar
    Indication: T-Cell Lymphoma Stage IV

Ifosfamide
    Indication: T-Cell Lymphoma Stage IV



Possible Methotrexate side effects in male

Reported by a individual with unspecified qualification from Norway on 2012-07-02

Patient: male

Reactions: Diarrhoea, Neutropenia

Drug(s) suspected as cause:
Mabthera
    Dosage: given after 3 months from the event

Methotrexate
    Indication: Granuloma

Methotrexate
    Indication: Vasculitis

Mabthera
    Indication: Rheumatoid Arthritis
    Start date: 2008-02-01



Possible Methotrexate side effects in female

Reported by a individual with unspecified qualification from Norway on 2012-07-02

Patient: female

Reactions: Neutropenia

Drug(s) suspected as cause:
Methotrexate
    Indication: Wegener's Granulomatosis

Mabthera
    Indication: Rheumatoid Arthritis
    Start date: 2008-09-01

Mabthera
    Dosage: given after 2 months from the event



Possible Methotrexate side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02

Patient:

Reactions: Extranodal NK / T-Cell Lymphoma, Nasal Type, Bone Marrow Failure, Neutropenia, Infection

Drug(s) suspected as cause:
Elspar
    Indication: T-Cell Lymphoma Stage IV

Methotrexate
    Indication: T-Cell Lymphoma Stage IV

Ifosfamide
    Indication: T-Cell Lymphoma Stage IV

Dexamethasone
    Indication: T-Cell Lymphoma Stage IV

Etoposide
    Indication: T-Cell Lymphoma Stage IV



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-06-28

Patient: female, weighing 44.5 kg (97.9 pounds)

Reactions: Hypotension, Pyrexia, Abdominal Pain Upper, Candida Test Positive, Simplex Virus Test Positive, Diarrhoea, Fungal Test Positive, Skin Lesion, Neutropenia, Klebsiella Test Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
PEG-L-Asparaginase (K-H)
    Dosage: 3225 unit

Cytarabine
    Dosage: 70 mg

Vincristine Sulfate
    Dosage: 3.88 mg

Methylprednisolone
    Dosage: 813.75 mg

Methotrexate
    Dosage: 15 mg



Possible Methotrexate side effects in 67 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-20

Patient: 67 year old female

Reactions: Cataract, Neuropathy Peripheral, Neutropenia

Drug(s) suspected as cause:
Vincristine
    Dosage: 1.4 mg/m2, (maximum 2 mg)
    Indication: Ocular Neoplasm

Procarbazine Hydrochloride
    Dosage: 100 mg/m2, unk
    Indication: Ocular Neoplasm

Methotrexate
    Dosage: 3.5 g/m2

Methotrexate
    Dosage: 400 ug once a week for 2 months, followed by monthly injection for 2 months
    Indication: Ocular Neoplasm

Rituximab
    Dosage: 375 mg/m2, unk
    Indication: Ocular Neoplasm

Other drugs received by patient: Radiation Therapy; Radiotherapy



Possible Methotrexate side effects in male

Reported by a individual with unspecified qualification from Italy on 2012-06-18

Patient: male

Reactions: Epstein-Barr Virus Infection, Diarrhoea, Anaemia, Sepsis, Cytomegalovirus Infection, Neutropenia, Thrombocytopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Burkitt's Lymphoma

Vincristine Sulfate
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Burkitt's Lymphoma

Cisplatin
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Burkitt's Lymphoma

Etoposide
    Indication: Burkitt's Lymphoma

Mabthera
    Indication: Burkitt's Lymphoma

Doxorubicin Hydrochloride
    Indication: Burkitt's Lymphoma



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-06-15

Patient: female

Reactions: Staphylococcal Infection, Device Related Infection, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 7 mg
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-29

Daunorubicin HCL
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Dasatinib
    Dosage: 45 mg
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-30

Methotrexate
    Dosage: 12 mg
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-23
    End date: 2012-04-23

Other drugs received by patient: Nystatin; Cytarabine; Vincristine Sulfate; Zantac; Pegaspargase; Zofran; Furosemide



Possible Methotrexate side effects in male

Reported by a physician from Italy on 2012-06-14

Patient: male

Reactions: Epstein-Barr Virus Infection, Anaemia, Cytomegalovirus Infection, Neutropenia, Thrombocytopenia, Disease Progression, Infection

Drug(s) suspected as cause:
Carmustine
    Indication: Burkitt's Lymphoma

Carboplatin
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Lymphoma

Etoposide
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Burkitt's Lymphoma

Vincristine
    Indication: Burkitt's Lymphoma

Melphalan Hydrochloride
    Indication: Burkitt's Lymphoma

Radiotherapy
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Cisplatin
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Burkitt's Lymphoma

Ifosfamide
    Indication: Burkitt's Lymphoma

Granulocyte Colony Stimulating Factor
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Burkitt's Lymphoma

Unknown Medication
    Dosage: antimicrobial prophylaxis
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Unknown Medication



Possible Methotrexate side effects in 17 year old female

Reported by a physician from United States on 2012-06-08

Patient: 17 year old female, weighing 47.6 kg (104.7 pounds)

Reactions: Blood Bilirubin Increased, Pyrexia, Caecitis, Loss of Consciousness, Oedema Peripheral, Pulmonary Oedema, Hypocalcaemia, Acute Respiratory Distress Syndrome, Melaena, Hypertriglyceridaemia, Epistaxis, Dysphagia, Anaemia, Hyperglycaemia, General Physical Health Deterioration, Eating Disorder, Tremor, Cerebral Infarction, Depressed Level of Consciousness, Neutropenia, Confusional State, Dyskinesia, Somnolence, Splenic Infarction, Hypokalaemia, Pleural Effusion, White Blood Cell Count Decreased, Cerebrovascular Accident, Ascites, Diarrhoea, Hypophagia, Hypoalbuminaemia, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 60mgm2 cyclic
    Administration route: Oral
    Indication: T-Cell Type Acute Leukaemia

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Cyclophosphamide
    Dosage: 1000mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Methotrexate
    Indication: T-Cell Type Acute Leukaemia

Oncaspar
    Indication: T-Cell Type Acute Leukaemia

Nelarabine
    Dosage: 650mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-04-13

Cytarabine
    Dosage: 75mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Dalteparin Sodium
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Nystatin; Lansoprazole; Insulin Aspart; Piperacillin and Tazobactam; Vancomycin; Voriconazole



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-06-05

Patient: female

Reactions: Neutropenia, Device Related Infection, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: itrc
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-23
    End date: 2012-04-23

Dasatinib
    Dosage: 45 milligram;
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-30

Cytarabine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-16

Daunorubicin Hydrochloride
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Dexamethasone
    Dosage: 2/1 day
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-29

Pegaspargase
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-19
    End date: 2012-04-19

Vincristine
    Dosage: 7 day
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-16
    End date: 2012-04-30

Other drugs received by patient: Furosemide; Nystatin; Zantac; Ondansetron



Possible Methotrexate side effects in 38 year old female

Reported by a physician from United States on 2012-06-01

Patient: 38 year old female

Reactions: Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-13

Mesna
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-13

Doxorubicin HCL
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Indication: Acute Lymphocytic Leukaemia

Dasatinib
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-13



Possible Methotrexate side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-25

Patient: female, weighing 14.9 kg (32.8 pounds)

Reactions: Anaemia, Hyponatraemia, Rash, Pyrexia, Ascites, Abdominal Pain Upper, Abdominal Compartment Syndrome, Respiratory Failure, Pneumonia Herpes Viral, Bone Marrow Failure, Neutropenia, Thrombocytopenia, Cardiac Arrest, Septic Shock, Infection in AN Immunocompromised Host

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: .99 mg

Methotrexate
    Dosage: 24.5 mg

Dexamethasone
    Dosage: 17.5 ml

Mercaptopurine
    Dosage: 460 mg



Possible Methotrexate side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-25

Patient: female, weighing 14.9 kg (32.8 pounds)

Reactions: Coagulopathy, Hepatic Failure, Pyrexia, Abdominal Pain Upper, Laboratory Test Abnormal, Malaise, Bone Marrow Failure, Thrombocytopenia, Anaemia, Condition Aggravated, Hyponatraemia, Rash, Varicella, Abdominal Compartment Syndrome, Ascites, Respiratory Failure, Pneumonia Herpes Viral, Neutropenia, Immune System Disorder, Cardiac Arrest, Septic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 460 mg

Dexamethasone
    Dosage: 17.5 mg

Vincristine Sulfate
    Dosage: .99 mg

Methotrexate
    Dosage: 24.5 mg



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