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Methotrexate (Methotrexate) - Nausea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Nausea (162)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate where reactions include nausea. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 162   Next >>

Possible Methotrexate side effects in female

Reported by a physician from Sweden on 2012-08-20

Patient: female

Reactions: Nausea, Progressive Multifocal Leukoencephalopathy, Hepatic Enzyme Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Azathioprine
    Dosage: 150 mg/day
    Administration route: Oral
    Indication: Polymyositis

Cyclophosphamide
    Dosage: 100 mg/day
    Administration route: Oral
    Indication: Polymyositis

Methotrexate
    Dosage: 20 mg/week
    Indication: Polymyositis

Methylprednisolone

Prednisone
    Dosage: 10mg daily

Prednisone
    Dosage: 17.5 mg/day
    Administration route: Oral

Prednisone
    Dosage: 60 mg/day

Prednisone
    Dosage: 2.5 mg/day

Prednisone
    Dosage: 40 mg/day
    Indication: Polymyositis



Possible Methotrexate side effects in female

Reported by a physician from Sweden on 2012-08-20

Patient: female

Reactions: Nausea, Progressive Multifocal Leukoencephalopathy, Hepatic Enzyme Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Azathioprine
    Dosage: 150 mg/day
    Administration route: Oral
    Indication: Polymyositis

Cyclophosphamide
    Dosage: 100 mg/day
    Administration route: Oral
    Indication: Polymyositis

Methotrexate
    Dosage: 20 mg/week
    Indication: Polymyositis

Methylprednisolone

Prednisone
    Dosage: 40 mg/day
    Indication: Polymyositis

Prednisone
    Dosage: 10mg daily

Prednisone
    Dosage: 17.5 mg/day
    Administration route: Oral

Prednisone
    Dosage: 60 mg/day

Prednisone
    Dosage: 2.5 mg/day



Possible Methotrexate side effects in female

Reported by a physician from Sweden on 2012-08-20

Patient: female

Reactions: Nausea, Progressive Multifocal Leukoencephalopathy, Hepatic Enzyme Increased

Adverse event resulted in: death

Drug(s) suspected as cause:
Azathioprine
    Dosage: 150 mg/day
    Administration route: Oral
    Indication: Polymyositis

Cyclophosphamide
    Dosage: 100 mg/day
    Administration route: Oral
    Indication: Polymyositis

Methotrexate
    Dosage: 20 mg/week
    Indication: Polymyositis

Methylprednisolone

Prednisone
    Dosage: 40 mg/day
    Indication: Polymyositis

Prednisone
    Dosage: 2.5 mg/day

Prednisone
    Dosage: 10mg daily

Prednisone
    Dosage: 60 mg/day

Prednisone
    Dosage: 17.5 mg/day
    Administration route: Oral



Possible Methotrexate side effects in 26 year old female

Reported by a consumer/non-health professional from Canada on 2012-08-16

Patient: 26 year old female

Reactions: Back Pain, Nausea, Ulcerative Keratitis

Drug(s) suspected as cause:
Methotrexate
    Dosage: inj

Orencia
    Dosage: last infusion on 11-may-2012,7aug12 lot # 2c80093 exp dt se2014 no of inf 6
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-12

Other drugs received by patient: Vitamin D; Oxycodone HCL; Plaquenil; Calcium; Prednisone TAB; Amlodipine; Omeprazole; Indocin; Folic Acid



Possible Methotrexate side effects in 21 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-14

Patient: 21 year old female

Reactions: Hyperbilirubinaemia, Fatigue, Nausea, Hyperglycaemia, Asthenia, Abdominal Pain Upper

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Daunorubicin HCL
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Leucovorin Calcium
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: high dose
    Indication: Acute Lymphocytic Leukaemia

PEG-Asparaginase
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Prednisone TAB
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: unk
    Indication: Acute Lymphocytic Leukaemia



Possible Methotrexate side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Sweden on 2012-08-13

Patient: 65 year old female

Reactions: Myositis, Dysphagia, Nausea, Ataxia, Hemiparesis, Hepatic Enzyme Increased, Dysarthria, Fatigue, Nystagmus, Balance Disorder, Quadriparesis, Vertigo, Arthritis, Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: death

Drug(s) suspected as cause:
Azathioprine Sodium
    Dosage: 150 mg, qd
    Administration route: Oral

Cyclophosphamide
    Dosage: 100 mg, qd
    Administration route: Oral

Methotrexate
    Dosage: 20 mg, qw

Prednisone TAB
    Dosage: 40 mg, qd
    Administration route: Oral

Prednisone TAB
    Dosage: 17.5 mg, qd
    Administration route: Oral

Prednisone TAB
    Dosage: 10 mg, qd
    Administration route: Oral

Prednisone TAB
    Dosage: 40 mg, qd
    Administration route: Oral

Prednisone TAB
    Dosage: 12.5 mg, qd
    Administration route: Oral

Other drugs received by patient: Methylprednisolone; Glucocorticoids; Heparin



Possible Methotrexate side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-13

Patient: 61 year old female

Reactions: Mucosal Inflammation, Nausea, Pyrexia, Diffuse Large B-Cell Lymphoma Recurrent, Oral Herpes

Adverse event resulted in: death

Drug(s) suspected as cause:
Bleomycin Sulfate
    Indication: Diffuse Large B-Cell Lymphoma

Cyclophosphamide
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin Hydrochloride
    Indication: Diffuse Large B-Cell Lymphoma

Etoposide
    Indication: Diffuse Large B-Cell Lymphoma

Methotrexate
    Indication: Diffuse Large B-Cell Lymphoma

Prednisolone
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Indication: Diffuse Large B-Cell Lymphoma



Possible Methotrexate side effects in 22 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-10

Patient: 22 year old male, weighing 93.1 kg (204.8 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Pain, Hyperglycaemia, Unresponsive To Stimuli, Pancytopenia, Disorientation, Pyrexia, Toxicity To Various Agents, Convulsion, Myalgia, Arthralgia, Chest Pain

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-07-20

Patient: female, weighing 75.0 kg (165.0 pounds)

Reactions: Abdominal Pain, Nausea, Flatulence

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis

Methotrexate
    Dosage: 25 mg, per week
    Start date: 2012-02-01
    End date: 2012-06-01



Possible Methotrexate side effects in

Reported by a physician from United Kingdom on 2012-07-17

Patient:

Reactions: Abdominal Pain, Tachycardia, Skin Toxicity, Pyrexia, Fatigue, Neuropathy Peripheral, Hepatotoxicity, Adverse Event, Dizziness, Oedema, Hallucination, Vomiting, Nausea, Gastrointestinal Toxicity, Neutropenic Sepsis, Nephropathy Toxic, Hypotension, Condition Aggravated, Adult T-Cell Lymphoma / Leukaemia, Mucosal Inflammation, Lung Disorder, Infection, Infusion Related Reaction

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Cytarabine
    Indication: Adult T-Cell Lymphoma / Leukaemia

Doxorubicin HCL
    Dosage: on day 1 of 21 day, (cycle 1-5)

Doxorubicin HCL
    Dosage: on day 1 of 21 day, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Hydrocortisone
    Indication: Adult T-Cell Lymphoma / Leukaemia

Methotrexate
    Indication: Adult T-Cell Lymphoma / Leukaemia

Prednisolone
    Dosage: on days 1-5 of 21 day cycle, (cycle 1-5)
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia

Radiotherapy
    Indication: Adult T-Cell Lymphoma / Leukaemia

Vincristine
    Dosage: (maximum 2 mg) on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Zenapax
    Dosage: on days 7 and 14 on cycle 1 of 21 day cycle
    Indication: Adult T-Cell Lymphoma / Leukaemia

Other drugs received by patient: Acyclovir; Thiabendazole; Cotrim; Itraconazole



Possible Methotrexate side effects in

Reported by a physician from United Kingdom on 2012-07-10

Patient:

Reactions: Abdominal Pain, Skin Toxicity, Tachycardia, Pyrexia, Fatigue, Neuropathy Peripheral, Hepatotoxicity, Adverse Event, Oedema, Dizziness, Hallucination, Vomiting, Gastrointestinal Toxicity, Nausea, Neutropenic Sepsis, Nephropathy Toxic, Hypotension, Adult T-Cell Lymphoma / Leukaemia, Condition Aggravated, Mucosal Inflammation, Lung Disorder, Infection, Infusion Related Reaction

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Cytarabine
    Indication: Adult T-Cell Lymphoma / Leukaemia

Doxorubicin HCL
    Dosage: on day 1 of 21 day, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Hydrocortisone
    Indication: Adult T-Cell Lymphoma / Leukaemia

Methotrexate
    Indication: Adult T-Cell Lymphoma / Leukaemia

Prednisolone
    Dosage: on days 1-5 of 21 day cycle, (cycle 1-5)
    Administration route: Oral
    Indication: Adult T-Cell Lymphoma / Leukaemia

Radiotherapy
    Indication: Adult T-Cell Lymphoma / Leukaemia

Vincristine
    Dosage: (maximum 2 mg) on day 1 of 21 day cycle, (cycle 1-5)
    Indication: Adult T-Cell Lymphoma / Leukaemia

Zenapax
    Dosage: on days 7 and 14 on cycle 1 of 21 day cycle
    Indication: Adult T-Cell Lymphoma / Leukaemia

Other drugs received by patient: Cotrim; Itraconazole; Thiabendazole; Acyclovir



Possible Methotrexate side effects in 10 year old female

Reported by a physician from Korea, Democratic People's Republic of on 2012-07-06

Patient: 10 year old female

Reactions: Vomiting, Wernicke's Encephalopathy, Nausea, Malnutrition, Mental Status Changes, Convulsion

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Cisplatin; Adriamycin PFS



Possible Methotrexate side effects in

Reported by a physician from United States on 2012-07-05

Patient:

Reactions: Fatigue, Central Nervous System Haemorrhage, Erythema Multiforme, Dyspnoea, Stomatitis, Vomiting, Gastrointestinal Toxicity, Nausea, Condition Aggravated, Rash, Haematotoxicity, Pulmonary Haemorrhage, Tumour Lysis Syndrome, Diarrhoea, Respiratory Failure, Neurological Symptom, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Leukaemia

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6

Prednisone
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Lymphoma

Prednisone
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Other drugs received by patient: Filgrastim; Unknown Medication; Leucovorin Calcium



Possible Methotrexate side effects in

Reported by a physician from United States on 2012-06-28

Patient:

Reactions: Fatigue, Central Nervous System Haemorrhage, Erythema Multiforme, Vomiting, Stomatitis, Dyspnoea, Gastrointestinal Toxicity, Nausea, Condition Aggravated, Rash, Haematotoxicity, Pulmonary Haemorrhage, Tumour Lysis Syndrome, Respiratory Failure, Diarrhoea, Neurological Symptom, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Leukaemia

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Leukaemia

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Unknown Medication; Leucovorin Calcium; Filgrastim



Possible Methotrexate side effects in male

Reported by a individual with unspecified qualification from United States on 2012-06-28

Patient: male, weighing 99.5 kg (218.9 pounds)

Reactions: Vomiting, Fatigue, Nausea, Blood Triglycerides Increased, Asthenia

Drug(s) suspected as cause:
Methotrexate
    Dosage: 570 mg

PEG-L-Asparaginase (K-H)
    Dosage: 5600 unit

Vincristine Sulfate
    Dosage: 4 mg



Possible Methotrexate side effects in 14 year old male

Reported by a individual with unspecified qualification from Japan on 2012-06-25

Patient: 14 year old male

Reactions: Dysphagia, Vomiting, Nausea, Hypophagia, Hearing Impaired, Oesophageal Stenosis

Drug(s) suspected as cause:
Cisplatin
    Dosage: 167 mg
    Indication: Bone Sarcoma

Doxorubicin HCL
    Dosage: 42 mg
    Indication: Bone Sarcoma

Etoposide
    Dosage: 84 mg
    Indication: Bone Sarcoma

Ifosfamide
    Dosage: 4200
    Indication: Bone Sarcoma

Methotrexate
    Dosage: 28 mg
    Indication: Bone Sarcoma



Possible Methotrexate side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-25

Patient:

Reactions: Fatigue, Central Nervous System Haemorrhage, Erythema Multiforme, Stomatitis, Vomiting, Dyspnoea, Nausea, Gastrointestinal Toxicity, Condition Aggravated, Rash, Haematotoxicity, Pulmonary Haemorrhage, Tumour Lysis Syndrome, Diarrhoea, Respiratory Failure, Neurological Symptom, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Lymphoma

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Unknown Medication; Leucovorin Calcium; Filgrastim



Possible Methotrexate side effects in 14 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-22

Patient: 14 year old male

Reactions: Vomiting, Nausea, Hearing Impaired, Oesophageal Stenosis

Drug(s) suspected as cause:
Cisplatin
    Indication: Bone Sarcoma

Doxorubicin HCL
    Indication: Bone Sarcoma

Etoposide
    Dosage: 2,6 courses
    Indication: Bone Sarcoma

Ifosfamide
    Dosage: inj.2,6 courses.
    Indication: Bone Sarcoma

Methotrexate



Possible Methotrexate side effects in female

Reported by a physician from France on 2012-06-21

Patient: female

Reactions: Weight Decreased, Nausea, Musculoskeletal Pain, Drug Intolerance, Spondylitis, Antinuclear Antibody Positive, Fatigue, Diarrhoea, Systemic Lupus Erythematosus, Hypoalbuminaemia, Arthritis, Decreased Appetite

Drug(s) suspected as cause:
Humira
    Indication: Crohn's Disease
    Start date: 2010-03-01

Methotrexate
    Dosage: weekly
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-03-16

Other drugs received by patient: Folic Acid



Possible Methotrexate side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-06-19

Patient: 47 year old male

Reactions: Mucosal Inflammation, Rash Generalised, Vomiting, Nausea, Pancytopenia, Pyrexia, Toxicity To Various Agents

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 62 year old female

Reported by a physician from Canada on 2012-06-19

Patient: 62 year old female

Reactions: Vomiting, Nausea, Condition Aggravated, Pancytopenia

Drug(s) suspected as cause:
Hydroxychloroquine Sulfate
    Indication: Lupus Nephritis

Methotrexate
    Administration route: Oral
    Indication: Condition Aggravated

Prednisone
    Indication: Lupus Nephritis



Possible Methotrexate side effects in 14 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-14

Patient: 14 year old male

Reactions: Vomiting, Nausea, Hearing Impaired, Oesophageal Stenosis

Drug(s) suspected as cause:
Cisplatin
    Dosage: 167mg
    Indication: Bone Sarcoma

Doxorubicin HCL
    Dosage: 42mg
    Indication: Bone Sarcoma

Etoposide
    Dosage: 84mg
    Indication: Bone Sarcoma

Ifosfamide
    Dosage: 4200mg
    Indication: Bone Sarcoma

Methotrexate
    Dosage: 28mg
    Indication: Bone Sarcoma



Possible Methotrexate side effects in 14 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-14

Patient: 14 year old male

Reactions: Vomiting, Nausea, Hearing Impaired, Oesophageal Stenosis

Drug(s) suspected as cause:
Cisplatin
    Dosage: 167mg
    Indication: Bone Sarcoma

Doxorubicin HCL
    Dosage: 42mg
    Indication: Bone Sarcoma

Etoposide
    Dosage: 84mg
    Indication: Bone Sarcoma

Ifosfamide
    Dosage: 4200mg
    Indication: Bone Sarcoma

Methotrexate
    Dosage: 28mg
    Indication: Bone Sarcoma



Possible Methotrexate side effects in 14 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-14

Patient: 14 year old male

Reactions: Vomiting, Nausea, Hearing Impaired, Oesophageal Stenosis

Drug(s) suspected as cause:
Cisplatin
    Dosage: 167mg
    Indication: Bone Sarcoma

Doxorubicin HCL
    Dosage: 42mg
    Indication: Bone Sarcoma

Etoposide
    Dosage: 84mg
    Indication: Bone Sarcoma

Ifosfamide
    Dosage: 4200mg
    Indication: Bone Sarcoma

Methotrexate
    Dosage: 28mg
    Indication: Bone Sarcoma



Possible Methotrexate side effects in 14 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-11

Patient: 14 year old male

Reactions: Dysphagia, Vomiting, Nausea, Oesophageal Stenosis

Drug(s) suspected as cause:
Cisplatin
    Dosage: 167 mg, unk
    Indication: Bone Sarcoma

Doxorubicin HCL
    Dosage: 42 mg, unk
    Indication: Bone Sarcoma

Etoposide
    Dosage: 84 mg, unk
    Indication: Bone Sarcoma

Ifosfamide
    Dosage: 4200 mg, unk
    Indication: Bone Sarcoma

Methotrexate
    Dosage: 28 mg, unk
    Indication: Bone Sarcoma



Possible Methotrexate side effects in 80 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-06-06

Patient: 80 year old female, weighing 59.0 kg (129.8 pounds)

Reactions: Abdominal Pain, Vomiting, Nausea, Drug Interaction, Transaminases Increased, Cholelithiasis, Alveolitis, Malaise, Respiratory Failure

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Amlodipine
    Dosage: 5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-11-01
    End date: 2009-05-15

Cordanum
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Tachyarrhythmia
    Start date: 2008-11-01
    End date: 2009-05-04

Falithrom
    Dosage: 3 mg, qd
    Administration route: Oral
    Indication: Tachyarrhythmia
    Start date: 2008-11-01
    End date: 2009-05-04

Methotrexate
    Dosage: 10 ml, qd
    Indication: Rheumatoid Arthritis
    Start date: 2008-11-01
    End date: 2009-05-04

Omeprazole
    Dosage: 20 mg, qd
    Administration route: Oral
    Indication: Prophylaxis Against Gastrointestinal Ulcer
    Start date: 2008-11-01
    End date: 2009-05-03

Ramipril
    Dosage: 2.5 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2000-01-01

Seroquel
    Dosage: 25 mg, qd
    Administration route: Oral
    Indication: Restlessness
    Start date: 2008-11-01

Simvastatin
    Dosage: 40 mg, qd
    Administration route: Oral
    Indication: Hyperlipidaemia
    Start date: 2008-11-01
    End date: 2009-05-05

Torsemide
    Dosage: 200 mg, qd
    Administration route: Oral
    Indication: Hypertension
    Start date: 2008-11-01

Other drugs received by patient: Ferrous Sulfate TAB; Digitoxin TAB; Xipamide; Prednisolone; Prednisolone; Folic Acid; Prednisolone; Actonel 35 Plus; Prednisolone; Prednisolone



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Canada on 2012-06-06

Patient: female

Reactions: Soft Tissue Infection, Nausea, Diarrhoea, Chills, Swelling, Pyrexia, Herpes Virus Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-04-18

Simponi
    Indication: Rheumatoid Arthritis
    Start date: 2010-02-02



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Brazil on 2012-06-06

Patient: female, weighing 65.0 kg (143.0 pounds)

Reactions: Rheumatoid Arthritis, Weight Increased, Nausea, Blood Triglycerides Increased, Depression, Abdominal Pain Upper

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2011-01-01

Remicade
    Dosage: 3 ampoules each
    Indication: Rheumatoid Arthritis
    Start date: 2012-03-01

Remicade
    Start date: 2012-05-16

Remicade
    Dosage: 2 ampoules each
    Start date: 2005-01-01



Possible Methotrexate side effects in 47 year old male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-06-04

Patient: 47 year old male

Reactions: Mucosal Inflammation, Rash Generalised, Vomiting, Nausea, Pancytopenia, Pyrexia, Drug Dispensing Error

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 68 year old female

Reported by a physician from United States on 2012-06-01

Patient: 68 year old female

Reactions: Oral Discomfort, Dysgeusia, Vomiting, Nausea, Decreased Appetite

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-24

Methotrexate
    Dosage: 22.5 mg, weekly
    Administration route: Oral

Methotrexate Sodium
    Dosage: tried injections briefly

Other drugs received by patient: Zofran; Folic Acid



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