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Methotrexate (Methotrexate) - Dyspnoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Dyspnoea (109)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate where reactions include dyspnoea. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 109   Next >>

Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-08-20

Patient: female, weighing 70.8 kg (155.8 pounds)

Reactions: Abdominal Pain, Hyperpyrexia, Anaphylactic Reaction, Chills, Pain, Hepatic Failure, Transaminases Increased, Splenic Infarction, Loss of Consciousness, Aortic Thrombosis, Off Label Use, Malaise, C-Reactive Protein Increased, Myositis, Dyspnoea, Hypotension, Arrhythmia, Lung Consolidation, Hypophosphataemia, Zygomycosis, Bacteraemia, Ventricular Tachycardia, Hyperammonaemia, Neutropenia, Hepatic Infarction, Shock, Infusion Related Reaction

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Cytarabine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Decadron Phosphate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23

Doxil
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Methotrexate
    Dosage: day 1
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2005-01-01
    End date: 2007-01-01

PEG-Asparaginase
    Dosage: day 2, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-25
    End date: 2007-10-25

Velcade
    Dosage: day 1, 4, 8 and 11
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23

Vincristine
    Dosage: day 1,8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2007-10-23
    End date: 2007-10-23



Possible Methotrexate side effects in 47 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-20

Patient: 47 year old female

Reactions: Rheumatoid Arthritis, Dyspnoea, Chest Pain, Drug Hypersensitivity, Heart Rate Abnormal, Inflammation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Dosage: half of a 40 mg pfs weekly

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2008-01-01

Methotrexate
    Dosage: 3 pills weekly
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Bupropion HCL; Meloxicam; Sulfasalazine; Pristiq; Folic Acid; Pilocarpine; Omeprazole; Bupropion HCL; Pristiq; Pilocarpine; Celebrex



Possible Methotrexate side effects in 65 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-13

Patient: 65 year old female

Reactions: Pneumonia, Dyspnoea, Cystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, qwk
    Indication: Product Used FOR Unknown Indication

Methotrexate
    Dosage: 25 mg, qwk

Other drugs received by patient: Clozaril; Plaquenil; Hydrochlorothiazide; Folic Acid; Synthroid



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: female, weighing 51.7 kg (113.8 pounds)

Reactions: Dyspnoea, Respiratory Disorder, Drug Ineffective, Skin Disorder, Abdominal Discomfort, Weight Increased, Fatigue, Dyspepsia, Insomnia, Adverse Event, Abnormal Loss of Weight, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2011-05-01
    End date: 2011-12-01

Methotrexate
    Administration route: Oral
    Start date: 2012-06-19

Methotrexate
    Administration route: Oral
    Start date: 2012-06-26

Methotrexate
    Dosage: 1 at breakfast and one at dinner
    Administration route: Oral
    Start date: 2012-07-03

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-07-10

Simponi
    Indication: Rheumatoid Arthritis
    Start date: 2012-07-01

Simponi
    Start date: 2011-03-01
    End date: 2011-04-01

Simponi
    Start date: 2012-06-14

Unspecified Nebulizer
    Indication: Respiratory Disorder
    Start date: 2011-07-01
    End date: 2011-01-01

Xopenex
    Indication: Respiratory Disorder
    Start date: 2011-07-01
    End date: 2011-01-01

Other drugs received by patient: Prednisone TAB; Prednisone TAB; Perforomist; Perforomist; Citracal D; Tylenol



Possible Methotrexate side effects in 64 year old female

Reported by a physician from United States on 2012-07-31

Patient: 64 year old female

Reactions: Dyspnoea, Shoulder Arthroplasty, Bone Pain, DRY Skin, Headache, Pyrexia, Full Blood Count Decreased, Blood Folate Decreased, Malaise, Arthralgia, Asthenia, Neck Surgery, Influenza Like Illness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: incd 0.9 to 0.6

Orencia
    Dosage: last infusion on 26mar12,18may12,at least 3 months
    Indication: Rheumatoid Arthritis
    Start date: 2012-03-26

Other drugs received by patient: Folic Acid



Possible Methotrexate side effects in 73 year old female

Reported by a physician from Germany on 2012-07-20

Patient: 73 year old female, weighing 42.0 kg (92.4 pounds)

Reactions: Weight Decreased, Dyspnoea, Septic Encephalopathy, Anaemia, General Physical Health Deterioration, Epilepsy, Pneumococcal Sepsis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-03-08
    End date: 2012-05-01

Methotrexate
    Dosage: once weekly, 7.5 mg once weekly
    Indication: Product Used FOR Unknown Indication
    Start date: 1994-01-01
    End date: 2012-06-01



Possible Methotrexate side effects in 81 year old male

Reported by a physician from United States on 2012-07-16

Patient: 81 year old male

Reactions: Dyspnoea, Arthralgia, Hypoxia, Chronic Obstructive Pulmonary Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-06

Methotrexate
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Plavix; Cardizem; Nitroglycerin; Unknown Medication; Aspirin



Possible Methotrexate side effects in 81 year old male

Reported by a physician from United States on 2012-07-14

Patient: 81 year old male

Reactions: Dyspnoea, Arthralgia, Hypoxia, Chronic Obstructive Pulmonary Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-06

Methotrexate
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Aspirin; Nitroglycerin; Plavix; Cardizem; Unknown Medication



Possible Methotrexate side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-13

Patient: male

Reactions: Dyspnoea

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Indication: Type 2 Diabetes Mellitus

Metformin Hydrochloride
    Indication: Type 2 Diabetes Mellitus

Methotrexate
    Dosage: stopped forever after 5 years of use
    Start date: 2010-09-08

Pioglitazone Hydrochloride
    Indication: Type 2 Diabetes Mellitus
    Start date: 2010-02-21

Saxagliptin
    Indication: Type 2 Diabetes Mellitus
    Start date: 2010-09-08



Possible Methotrexate side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-06

Patient: male

Reactions: Pneumonia, Dyspnoea, Throat Irritation, Vocal Cord Paralysis, Varicella

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Start date: 2008-01-01

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2007-01-01

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2007-01-01

Other drugs received by patient: Plaquenil



Possible Methotrexate side effects in

Reported by a physician from United States on 2012-07-05

Patient:

Reactions: Fatigue, Central Nervous System Haemorrhage, Erythema Multiforme, Dyspnoea, Stomatitis, Vomiting, Gastrointestinal Toxicity, Nausea, Condition Aggravated, Rash, Haematotoxicity, Pulmonary Haemorrhage, Tumour Lysis Syndrome, Diarrhoea, Respiratory Failure, Neurological Symptom, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Leukaemia

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Dexamethasone Sodium Phosphate
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6

Prednisone
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Lymphoma

Prednisone
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Other drugs received by patient: Filgrastim; Unknown Medication; Leucovorin Calcium



Possible Methotrexate side effects in 70 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-03

Patient: 70 year old female, weighing 81.6 kg (179.6 pounds)

Reactions: Pneumocystis Jiroveci Pneumonia, Dyspnoea, Oxygen Consumption Increased, Acute Interstitial Pneumonitis, Crepitations, Influenza Like Illness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 67 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-06-29

Patient: 67 year old female

Reactions: Dyspnoea, Tachycardia, Pyrexia, Feeling Cold, Speech Disorder, Cyanosis, Crepitations, Tachypnoea, Cough, Pneumonitis

Adverse event resulted in: death

Drug(s) suspected as cause:
Adalimumab
    Dosage: 40 mg, unk
    Indication: Arthropathy

Methotrexate
    Dosage: 20 mg, qw
    Indication: Rheumatoid Arthritis

Prednisone TAB
    Dosage: 5 mg, qd
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in 81 year old male

Reported by a physician from United States on 2012-06-29

Patient: 81 year old male

Reactions: Dyspnoea, Hypoxia, Chronic Obstructive Pulmonary Disease

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-06

Methotrexate
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Cardizem; Aspirin; Plavix; Nitroglycerin



Possible Methotrexate side effects in

Reported by a physician from United States on 2012-06-28

Patient:

Reactions: Fatigue, Central Nervous System Haemorrhage, Erythema Multiforme, Vomiting, Stomatitis, Dyspnoea, Gastrointestinal Toxicity, Nausea, Condition Aggravated, Rash, Haematotoxicity, Pulmonary Haemorrhage, Tumour Lysis Syndrome, Respiratory Failure, Diarrhoea, Neurological Symptom, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Leukaemia

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Leukaemia

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Unknown Medication; Leucovorin Calcium; Filgrastim



Possible Methotrexate side effects in 64 year old female

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: 64 year old female

Reactions: Dyspnoea, Shoulder Arthroplasty, Bone Pain, Pyrexia, DRY Skin, Headache, Full Blood Count Decreased, Blood Folate Decreased, Malaise, Arthralgia, Asthenia, Neck Surgery, Influenza Like Illness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: incd 0.9 to 0.6

Orencia
    Dosage: last infusion on 26mar12,18may12,at least 3 months
    Indication: Rheumatoid Arthritis
    Start date: 2012-03-26

Other drugs received by patient: Folic Acid



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-06-27

Patient: female, weighing 91.0 kg (200.2 pounds)

Reactions: Dyspnoea, Stomatitis, Pruritus, Cystitis, Herpes Virus Infection, Infusion Related Reaction

Drug(s) suspected as cause:
Methotrexate
    Indication: Product Used FOR Unknown Indication

Remicade
    Indication: Crohn's Disease
    Start date: 2009-07-13

Remicade
    Start date: 2012-06-16

Remicade
    Start date: 2012-06-16

Remicade
    Indication: Arthritis
    Start date: 2009-07-13

Other drugs received by patient: Mesalamine; Gabapentin; Tylenol W / Codeine NO. 3; Folic Acid; Valproic Acid; Flexinol; Gravol TAB; Lipitor; Multi-Vitamins; Demerol; Prednisone TAB; Benadryl; ALL Other Therapeutics; Acetaminophen



Possible Methotrexate side effects in 74 year old male

Reported by a consumer/non-health professional from United States on 2012-06-27

Patient: 74 year old male

Reactions: Dyspnoea, Pulmonary Embolism, Toxicity To Various Agents

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Proair HFA; Zolpidem; Nifedipine; Spiriva; Albuterol; Omeprazole; Prednisone TAB; Ciprofloxacin



Possible Methotrexate side effects in female

Reported by a physician from Germany on 2012-06-25

Patient: female

Reactions: Dyspnoea, Restlessness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mabthera
    Indication: Rheumatoid Arthritis
    Start date: 2011-06-09
    End date: 2011-06-09

Methotrexate
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Prednisolone



Possible Methotrexate side effects in 58 year old female

Reported by a physician from Canada on 2012-06-25

Patient: 58 year old female, weighing 73.8 kg (162.4 pounds)

Reactions: Dyspnoea, Pneumonia, Anaemia, Lung Infection, Muscular Weakness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Arava
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2011-01-01

Cimzia
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-18
    End date: 2012-05-01

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2011-03-01
    End date: 2012-05-01

Other drugs received by patient: Diltiazem Hydrocholoride; Diclofenac Sodium; Atacand



Possible Methotrexate side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-25

Patient:

Reactions: Fatigue, Central Nervous System Haemorrhage, Erythema Multiforme, Stomatitis, Vomiting, Dyspnoea, Nausea, Gastrointestinal Toxicity, Condition Aggravated, Rash, Haematotoxicity, Pulmonary Haemorrhage, Tumour Lysis Syndrome, Diarrhoea, Respiratory Failure, Neurological Symptom, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: days 1-5 during cycle 3,5 and 7

Cyclophosphamide
    Dosage: for 5 days in cycle 1
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Dexamethasone
    Dosage: on days 1-5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Dexamethasone
    Dosage: on days 1-5 of cycle 2,4 and 6

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4 and 5 of cycle 3,5 and 7
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Etoposide
    Dosage: on days 4 and 5 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5 in cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7

Methotrexate
    Dosage: on day 1 of cycle 2,4 and 6

Methotrexate
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Lymphoma

Prednisone TAB
    Dosage: for 7 days in cycle 1
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: on day 8 from cycle 3 to 7

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Leukaemia

Rituximab
    Dosage: day 8 on cycle 2; doage increased to 375 mg/m2 on day 10 and 12
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1 of cycle 2,4 and 6

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7

Vincristine
    Dosage: on day 1 of cycle 3,5 and 7
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Unknown Medication; Leucovorin Calcium; Filgrastim



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-06-22

Patient: female, weighing 154.2 kg (339.3 pounds)

Reactions: Nasopharyngitis, Hyperhidrosis, Pericardial Effusion, Weight Increased, Interstitial Lung Disease, Chest Pain, Pneumonitis, Cough, Back Pain, Pneumonia, Dyspnoea, Drug Hypersensitivity, Lung Neoplasm, Costochondritis, Pulmonary Fibrosis, Lymphadenopathy Mediastinal, Compression Fracture, Sleep Apnoea Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Administration route: Oral
    Indication: Psoriatic Arthropathy
    Start date: 2010-10-01
    End date: 2012-01-31

Remicade
    Dosage: dose also reported as 660 mg
    Start date: 2011-08-02
    End date: 2011-08-02

Remicade
    Indication: Psoriatic Arthropathy
    Start date: 2010-11-16

Other drugs received by patient: Prednisone TAB; Other Therapeutic Product; Biotin; Vitamin D



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Canada on 2012-06-15

Patient: female, weighing 70.4 kg (154.8 pounds)

Reactions: Dyspnoea, Nasopharyngitis, Angina Pectoris, Hypotension, Incorrect Dose Administered, Vocal Cord Disorder, Laryngitis, Pericarditis, Diarrhoea, Alopecia, Blood Cholesterol Increased, Myocardial Infarction, Myocarditis, Fluid Retention

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2008-09-22

Leucovorin Calcium
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Methotrexate
    Dosage: 4 tablets a week
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Vitamin D; Celebrex



Possible Methotrexate side effects in 66 year old female

Reported by a consumer/non-health professional from United Kingdom on 2012-06-14

Patient: 66 year old female

Reactions: Chest Discomfort, Dyspnoea, Haemoptysis, Emotional Distress, Malaise, Alopecia, Liver Function Test Abnormal, Cough, Pneumonitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Adcal-D3
    Dosage: 1 df, daily
    Indication: Osteoporosis
    Start date: 2011-05-25

Alendronate Sodium
    Dosage: 70 mg, unk
    Indication: Osteoporosis
    Start date: 2011-05-25

Methotrexate
    Dosage: 17.5 mg, qw
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2011-02-07
    End date: 2012-04-26

Pravastatin
    Dosage: 40 mg, unk
    Indication: Blood Cholesterol
    Start date: 2012-01-17

Other drugs received by patient: Ramipril; Tolterodine Tartrate; Betahistine; Fluticasone Propionate / Salmeterol; Omeprazole; Naproxen; Valproic Acid; Fluoxetine; Levothyroxine Sodium; Leucovorin Calcium



Possible Methotrexate side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-13

Patient: male

Reactions: Pneumonia, Dyspnoea, Throat Irritation, Vocal Cord Paralysis, Varicella

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2007-01-01

Humira
    Start date: 2008-01-01

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2007-01-01

Other drugs received by patient: Plaquenil



Possible Methotrexate side effects in 69 year old female

Reported by a consumer/non-health professional from United States on 2012-06-13

Patient: 69 year old female, weighing 104.0 kg (228.8 pounds)

Reactions: Dyspnoea, Body Temperature Increased, Coma, Cardiac Disorder, Feeling Cold

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate

Orencia
    Dosage: last dose on:aug2010
    Indication: Rheumatoid Arthritis
    Start date: 2010-01-01

Other drugs received by patient: Morphine; Vitamin TAB; Percocet; Prednisone TAB



Possible Methotrexate side effects in female

Reported by a individual with unspecified qualification from United States on 2012-06-12

Patient: female, weighing 73.0 kg (160.6 pounds)

Reactions: Myositis, Dyspnoea, Chest Discomfort, Tachycardia, Muscular Weakness, Culture Urine Positive, Motor Neurone Disease, Myalgia, Escherichia Test Positive, Ejection Fraction Decreased, Grip Strength Decreased, Asthenia, Klebsiella Test Positive, Influenza

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Allopurinol
    Dosage: 300 mg

Cytarabine
    Dosage: 70 mg

Daunorubicin HCL
    Dosage: 45.5 mg

Methotrexate
    Dosage: 15 mg

PEG-L-Asparaginase (K-H)
    Dosage: 2500 iu

Vincristine Sulfate
    Dosage: 1.5 mg



Possible Methotrexate side effects in 77 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-08

Patient: 77 year old male, weighing 42.4 kg (93.3 pounds)

Reactions: Dyspnoea, Lung Neoplasm, Lymphadenopathy Mediastinal, Burkitt's Lymphoma, Pleural Effusion, Respiratory Distress

Adverse event resulted in: death

Drug(s) suspected as cause:
Methotrexate
    Dosage: 6 mg, qw
    Indication: Rheumatoid Arthritis
    End date: 2010-01-01

Tacrolimus
    Dosage: 1 mg, unk
    Indication: Joint Swelling
    Start date: 2010-04-01
    End date: 2010-07-01



Possible Methotrexate side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-07

Patient: male

Reactions: Dyspnoea, Pneumonia, Throat Irritation, Vocal Cord Paralysis, Varicella

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2007-01-01

Humira
    Start date: 2008-01-01

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2005-01-01
    End date: 2007-01-01

Other drugs received by patient: Plaquenil



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Brazil on 2012-06-05

Patient: female, weighing 69.5 kg (152.9 pounds)

Reactions: Dyspnoea, Tachycardia, Pain, Dizziness, Headache

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis

Remicade
    Indication: Rheumatoid Arthritis
    Start date: 2012-05-24

Other drugs received by patient: Prednisolone; Diclofenac Sodium; Fluoxetine HCL; Clonazepam



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