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Methotrexate (Methotrexate) - Drug Ineffective - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Ineffective (103)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate where reactions include drug ineffective. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 103   Next >>

Possible Methotrexate side effects in 45 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-08-27

Patient: 45 year old female

Reactions: Drug Ineffective, Systemic Lupus Erythematosus, Alopecia, Leukopenia

Drug(s) suspected as cause:
Infliximab, Recombinant
    Dosage: 0 (initial dose of 3 mg/kg), 2, and 6 weeks and then every 8 weeks
    Indication: Rheumatoid Arthritis

Methotrexate
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: female, weighing 68.0 kg (149.7 pounds)

Reactions: Drug Dose Omission, Inappropriate Schedule of Drug Administration, Incorrect Drug Administration Duration, Hot Flush, Drug Ineffective, Withdrawal Syndrome, Drug Prescribing Error, Muscle Twitching

Drug(s) suspected as cause:
Fentanyl-100
    Dosage: every 60 hours
    Indication: Back Pain
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Fibromyalgia
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Arthritis
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Pain
    Start date: 2007-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2007-01-01



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: female, weighing 68.0 kg (149.7 pounds)

Reactions: Inappropriate Schedule of Drug Administration, Drug Ineffective

Drug(s) suspected as cause:
Duragesic-100
    Indication: Back Pain
    Start date: 2007-01-01
    End date: 2012-01-01

Duragesic-100
    Indication: Fibromyalgia
    Start date: 2007-01-01
    End date: 2012-01-01

Duragesic-100
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01
    End date: 2012-01-01

Duragesic-100
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2007-01-01



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: female, weighing 68.0 kg (149.7 pounds)

Reactions: Inappropriate Schedule of Drug Administration, Drug Dose Omission, Hot Flush, Incorrect Drug Administration Duration, Drug Ineffective, Withdrawal Syndrome, Muscle Twitching, Drug Prescribing Error

Drug(s) suspected as cause:
Fentanyl-100
    Dosage: every 60 hours
    Indication: Back Pain
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Pain
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Arthritis
    Start date: 2007-01-01
    End date: 2012-01-01

Fentanyl-100
    Dosage: every 60 hours
    Indication: Fibromyalgia
    Start date: 2007-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100 mg, 50 mg every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2007-01-01



Possible Methotrexate side effects in male

Reported by a physician from Japan on 2012-08-14

Patient: male

Reactions: Interstitial Lung Disease, Drug Ineffective

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Indication: Product Used FOR Unknown Indication

Ustekinumab
    Start date: 2012-02-28
    End date: 2012-02-28

Ustekinumab
    Start date: 2011-12-06
    End date: 2011-12-06

Ustekinumab
    Indication: Psoriasis
    Start date: 2011-11-08
    End date: 2011-11-08

Other drugs received by patient: ALL Other Therapeutic Products; Tigason; ALL Other Therapeutic Products; Cyclosporine; Cyclosporine; Cyclosporine



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-13

Patient: female, weighing 68.0 kg (149.7 pounds)

Reactions: Inappropriate Schedule of Drug Administration, Drug Ineffective

Drug(s) suspected as cause:
Duragesic-100
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01
    End date: 2012-01-01

Duragesic-100
    Indication: Back Pain
    Start date: 2007-01-01
    End date: 2012-01-01

Duragesic-100
    Indication: Fibromyalgia
    Start date: 2007-01-01
    End date: 2012-01-01

Duragesic-100
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Methotrexate
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone Hydrochloride
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Oxycodone Hydrochloride (Oxycontin)
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2012-01-01
    End date: 2012-01-01

Percocet
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-01
    End date: 2012-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Intervertebral Disc Degeneration
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Fibromyalgia
    Start date: 2007-01-01

Tramadol HCL
    Dosage: 100mg/tablet/50mg/every 4-6 hours
    Administration route: Oral
    Indication: Back Pain
    Start date: 2007-01-01



Possible Methotrexate side effects in 55 year old female

Reported by a physician from France on 2012-08-10

Patient: 55 year old female

Reactions: Drug Ineffective, Pain, Sinus Disorder, Hemiparesis, Multiple Sclerosis, Transient Ischaemic Attack

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2010-10-01
    End date: 2012-05-01

Methotrexate
    Dosage: 10 mg, weekly

Methotrexate
    Dosage: 7.5 mg, qwk
    Start date: 2010-12-21

Methotrexate
    Dosage: 10 mg, weekly
    Start date: 2009-01-01

Methotrexate
    Dosage: 15 mg, weekly
    Indication: Polyarthritis

Methotrexate
    Dosage: 7.5 mg, weekly
    Start date: 2010-10-01

Other drugs received by patient: Lansoprazole; Flector / 00372302 /; Lamaline / 00764901 /; Flector / 00372302 /; Folic Acid



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: female, weighing 51.7 kg (113.8 pounds)

Reactions: Dyspnoea, Respiratory Disorder, Drug Ineffective, Skin Disorder, Abdominal Discomfort, Weight Increased, Fatigue, Dyspepsia, Insomnia, Adverse Event, Abnormal Loss of Weight, Asthenia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Rheumatoid Arthritis
    Start date: 2011-05-01
    End date: 2011-12-01

Methotrexate
    Administration route: Oral
    Start date: 2012-06-19

Methotrexate
    Administration route: Oral
    Start date: 2012-06-26

Methotrexate
    Dosage: 1 at breakfast and one at dinner
    Administration route: Oral
    Start date: 2012-07-03

Methotrexate
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-07-10

Simponi
    Indication: Rheumatoid Arthritis
    Start date: 2012-07-01

Simponi
    Start date: 2011-03-01
    End date: 2011-04-01

Simponi
    Start date: 2012-06-14

Unspecified Nebulizer
    Indication: Respiratory Disorder
    Start date: 2011-07-01
    End date: 2011-01-01

Xopenex
    Indication: Respiratory Disorder
    Start date: 2011-07-01
    End date: 2011-01-01

Other drugs received by patient: Prednisone TAB; Prednisone TAB; Perforomist; Perforomist; Citracal D; Tylenol



Possible Methotrexate side effects in 50 year old male

Reported by a physician from Italy on 2012-08-08

Patient: 50 year old male

Reactions: Chondropathy, Drug Ineffective, Oral Disorder, Salivary Gland Adenoma, Salivary Gland Enlargement, Nerve Compression

Drug(s) suspected as cause:
Adalimumab
    Dosage: 40 mg, biweekly
    Indication: Chondropathy

Cyclosporine
    Indication: Psoriasis

Methotrexate
    Indication: Psoriasis



Possible Methotrexate side effects in 36 year old female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-08-06

Patient: 36 year old female

Reactions: Drug Ineffective

Drug(s) suspected as cause:
Azathioprine Sodium
    Indication: Systemic Lupus Erythematosus

Hydroxychloroquine Sulfate
    Indication: Systemic Lupus Erythematosus

Kiovig

Kiovig
    Indication: Systemic Lupus Erythematosus

Methotrexate
    Indication: Systemic Lupus Erythematosus



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Germany on 2012-08-02

Patient: female

Reactions: Rheumatoid Arthritis, Fatigue, Drug Ineffective, Foot Operation, Pyrexia, Finger Deformity

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Indication: Psoriatic Arthropathy
    Start date: 2009-05-06
    End date: 2010-12-25

Humira
    End date: 2012-05-10

Methotrexate
    Indication: Psoriatic Arthropathy
    Start date: 2011-01-01

Other drugs received by patient: Voltaren; Antihypertensive Medication; Tramadol HCL; Omeprazole



Possible Methotrexate side effects in 79 year old female

Reported by a consumer/non-health professional from Colombia on 2012-08-02

Patient: 79 year old female

Reactions: Blood Pressure Increased, Drug Ineffective, Urinary Tract Infection, Varicophlebitis, Headache, Gastritis, Transaminases Abnormal, Gait Disturbance, Arthritis

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2009-10-01
    End date: 2009-12-01

Enbrel
    Dosage: 50 mg, weekly
    Start date: 2010-07-01
    End date: 2010-09-01

Methotrexate
    Dosage: unknown
    Administration route: Oral
    Indication: Arthritis
    Start date: 2000-01-01

Olmesartan Medoxomil and Hydrochlorothizide
    Dosage: 40/12.5 mg, 1x/day
    Administration route: Oral
    Indication: Hypertension
    Start date: 2006-01-01

Other drugs received by patient: Prednisolone; Prednisolone



Possible Methotrexate side effects in 80 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-02

Patient: 80 year old male

Reactions: Drug Ineffective, Physical Disability

Drug(s) suspected as cause:
Leflunomide
    Dosage: unk
    Indication: Rheumatoid Arthritis

Methotrexate
    Dosage: unk
    Indication: Rheumatoid Arthritis

Sulfasalazine
    Dosage: unk
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-26

Patient: female, weighing 62.6 kg (137.7 pounds)

Reactions: Drug Ineffective, Crohn's Disease, Rheumatoid Nodule, Hypertension

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    End date: 2012-01-01

Remicade
    Start date: 2012-07-05

Remicade
    Dosage: started at least 5 years ago
    Indication: Crohn's Disease
    End date: 2012-01-01

Remicade
    Dosage: started at least 5 years ago
    Indication: Rheumatoid Arthritis
    End date: 2012-01-01

Remicade
    Start date: 2012-07-05



Possible Methotrexate side effects in 9 year old male

Reported by a physician from Japan on 2012-07-25

Patient: 9 year old male

Reactions: Graft Versus Host Disease, Drug Ineffective, Pneumatosis Intestinalis

Drug(s) suspected as cause:
Methotrexate
    Indication: Prophylaxis Against Graft Versus Host Disease

Methylprednisolone
    Indication: Prophylaxis Against Graft Versus Host Disease

Prograf
    Dosage: unk
    Indication: Prophylaxis Against Graft Versus Host Disease

Other drugs received by patient: Cellcept; Remicade



Possible Methotrexate side effects in 28 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-23

Patient: 28 year old female

Reactions: Drug Ineffective, Urticaria, Skin Disorder

Drug(s) suspected as cause:
Enbrel
    Dosage: unk
    Start date: 2011-09-01
    End date: 2011-10-21

Enbrel
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 2011-09-01

Methotrexate
    Dosage: 15 mg, weekly
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Diprosone; Folic Acid; Diprosone / 00008502 /



Possible Methotrexate side effects in 79 year old female

Reported by a consumer/non-health professional from Colombia on 2012-07-20

Patient: 79 year old female

Reactions: Blood Pressure Increased, Drug Ineffective, Urinary Tract Infection, Varicophlebitis, Headache, Transaminases Abnormal, Gastritis, Gait Disturbance, Arthritis

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Enbrel
    Dosage: 50 mg, weekly
    Indication: Rheumatoid Arthritis
    Start date: 2009-10-01
    End date: 2009-12-01

Enbrel
    Dosage: 50 mg, weekly
    Start date: 2010-07-01
    End date: 2010-09-01

Methotrexate
    Dosage: unknown
    Administration route: Oral
    Indication: Arthritis
    Start date: 2000-01-01

Olmesartan Medoxomil and Hydrochlorothizide
    Dosage: 40/12.5 mg, 1x/day
    Indication: Hypertension
    Start date: 2006-01-01

Other drugs received by patient: Prednisolone; Prednisolone



Possible Methotrexate side effects in 58 year old male

Reported by a health professional (non-physician/pharmacist) from Spain on 2012-07-19

Patient: 58 year old male

Reactions: Skin Papilloma, Drug Ineffective

Drug(s) suspected as cause:
Corticosteroids
    Administration route: Topical
    Indication: Psoriasis

Methotrexate
    Administration route: Oral
    Indication: Psoriasis



Possible Methotrexate side effects in 88 year old female

Reported by a consumer/non-health professional from United States on 2012-07-19

Patient: 88 year old female, weighing 81.7 kg (179.6 pounds)

Reactions: Pain in Extremity, Drug Ineffective, Insomnia, Unevaluable Event

Drug(s) suspected as cause:
Hydrocodone Bitartrate
    Indication: Rheumatoid Arthritis
    Start date: 1993-01-01

Methotrexate
    Indication: Rheumatoid Arthritis

Remicade
    Indication: Rheumatoid Arthritis

Tylenol
    Indication: Rheumatoid Arthritis

Tylenol



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Brazil on 2012-07-18

Patient: female, weighing 58.0 kg (127.6 pounds)

Reactions: Pruritus, Drug Ineffective, Urinary Incontinence, Fall, Vaginal Haemorrhage, Liver Disorder, Rheumatoid Arthritis, Unevaluable Event, Gastrooesophageal Reflux Disease, Nervousness, Acne, Immunodeficiency, Neoplasm Malignant, Mental Disorder, Gait Disturbance, Leukocytosis, Depressed Mood, Herpes Virus Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis
    Start date: 2009-06-01
    End date: 2012-02-01

Bacitracin Zinc and Neomycin Sulfate
    Indication: Laceration

Boniva
    Indication: Osteoporosis

Mabthera
    Dosage: dose: 1000 mg/ml, fortnightly in each semester
    Indication: Rheumatoid Arthritis
    Start date: 2010-11-03
    End date: 2010-11-18

Mabthera

Methotrexate
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Arava; Caltrate 600 + D; Zovirax; Centrum; Voltaren; Endofolin; Calcium



Possible Methotrexate side effects in 10 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-12

Patient: 10 year old male

Reactions: Cataract, Drug Ineffective, Toxic Encephalopathy, Toxicity To Various Agents, Graft Versus Host Disease in Skin, Pancreatitis, Thrombocytopenia, Hypertension, Hypogammaglobulinaemia

Drug(s) suspected as cause:
Cyclosporine
    Indication: Bone Marrow Transplant

Methotrexate
    Indication: Bone Marrow Transplant

Methylprednisolone
    Indication: Bone Marrow Transplant

Mycophenolate Mofetil
    Indication: Bone Marrow Transplant

Prednisolone
    Dosage: 3 mg, unk
    Indication: Bone Marrow Transplant

Tacrolimus
    Indication: Bone Marrow Transplant



Possible Methotrexate side effects in 10 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-12

Patient: 10 year old male

Reactions: Cataract, Toxic Encephalopathy, Drug Ineffective, Toxicity To Various Agents, Graft Versus Host Disease in Skin, Pancreatitis, Hypogammaglobulinaemia, Thrombocytopenia, Hypertension

Drug(s) suspected as cause:
Cyclosporine
    Indication: Bone Marrow Transplant

Methotrexate
    Indication: Bone Marrow Transplant

Methylprednisolone
    Indication: Bone Marrow Transplant

Mycophenolate Mofetil
    Indication: Bone Marrow Transplant

Prednisolone
    Dosage: 3 mg, unk
    Indication: Bone Marrow Transplant

Tacrolimus
    Indication: Bone Marrow Transplant



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-11

Patient: female

Reactions: Drug Ineffective, Knee Arthroplasty

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: (Etanercept)



Possible Methotrexate side effects in female

Reported by a physician from United Kingdom on 2012-07-09

Patient: female

Reactions: Drug Ineffective, Knee Arthroplasty

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Naproxen; Calcichew D3; Etanercept; Folic Acid



Possible Methotrexate side effects in 88 year old female

Reported by a consumer/non-health professional from United States on 2012-07-06

Patient: 88 year old female, weighing 81.6 kg (179.6 pounds)

Reactions: Drug Ineffective

Drug(s) suspected as cause:
Acetaminophen
    Dosage: unk
    Indication: Rheumatoid Arthritis

Hydrocodone
    Dosage: unk
    Indication: Rheumatoid Arthritis
    Start date: 1993-01-01

Lyrica
    Dosage: 200 mg, 2x/day
    Administration route: Oral
    Indication: Diabetic Neuropathy

Methotrexate
    Dosage: 10.5 mg, weekly
    Indication: Rheumatoid Arthritis

Remicade
    Dosage: unk
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in 55 year old female

Reported by a consumer/non-health professional from United States on 2012-07-06

Patient: 55 year old female

Reactions: Scleritis, Activities of Daily Living Impaired, Drug Ineffective, Adrenal Insufficiency, Bone Density Decreased, Depression, Feeling Abnormal, Spondylitis

Drug(s) suspected as cause:
Methotrexate
    Indication: Psoriatic Arthropathy

Prednisone TAB
    Indication: Psoriatic Arthropathy

Prednisone TAB

Remicade
    Dosage: therapy duration of over a year
    Indication: Psoriatic Arthropathy

Other drugs received by patient: Phenergan HCL; Flexeril; Oxycodone HCL



Possible Methotrexate side effects in 55 year old female

Reported by a consumer/non-health professional from United States on 2012-07-05

Patient: 55 year old female

Reactions: Scleritis, Activities of Daily Living Impaired, Drug Ineffective, Adrenal Insufficiency, Bone Density Decreased, Depression, Feeling Abnormal, Spondylitis

Drug(s) suspected as cause:
Methotrexate
    Indication: Psoriatic Arthropathy

Prednisone
    Indication: Psoriatic Arthropathy

Prednisone

Remicade
    Dosage: therapy duration of over a year
    Indication: Psoriatic Arthropathy

Other drugs received by patient: Flexeril; Oxycodone HCL; Phenergan HCL



Possible Methotrexate side effects in 55 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-05

Patient: 55 year old female

Reactions: Malaise, Drug Ineffective

Drug(s) suspected as cause:
Methotrexate

Remicade
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in female

Reported by a consumer/non-health professional from Canada on 2012-07-02

Patient: female, weighing 134.0 kg (294.8 pounds)

Reactions: Pyoderma Gangrenosum, Drug Ineffective

Drug(s) suspected as cause:
Methotrexate
    Indication: Pyoderma Gangrenosum

Remicade
    Indication: Pyoderma Gangrenosum
    Start date: 2011-01-12

Other drugs received by patient: Prednisone TAB



Possible Methotrexate side effects in 41 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-25

Patient: 41 year old female

Reactions: Drug Ineffective, Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: life threatening event, hospitalization, disablity

Drug(s) suspected as cause:
Infliximab
    Indication: Dermatomyositis
    Start date: 2008-03-13
    End date: 2008-08-21

Methotrexate
    Indication: Dermatomyositis
    Start date: 2006-06-01

Prednisone TAB
    Administration route: Oral
    Indication: Dermatomyositis
    Start date: 2006-05-01

Rituxan
    Dosage: on days 1 and 15
    Start date: 2008-10-13

Rituxan
    Indication: Dermatomyositis
    Start date: 2009-08-13

Rituxan
    Dosage: this was the last dose prior to sae onset lot numbers for this dose was 720648, 720649.
    Start date: 2008-10-27

Rituxan
    Dosage: one days 1 and 15
    Start date: 2007-07-01

Other drugs received by patient: Tramadol Hydrochl; Hydrochlorothiazide; Actonel; Folic Acid



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