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Methotrexate (Methotrexate) - Anaemia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Anaemia (115)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Methotrexate where reactions include anaemia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 115   Next >>

Possible Methotrexate side effects in 69 year old female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: 69 year old female, weighing 80.7 kg (177.6 pounds)

Reactions: Pneumonia, Hypotension, Anaemia, Encephalopathy, Hyponatraemia, Rheumatoid Arthritis, Sepsis, Dehydration, Altered State of Consciousness, Type 1 Diabetes Mellitus, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 7.5 mg, unk
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Prolia
    Dosage: 60 mg, q6mo
    Indication: Osteoporosis Postmenopausal
    Start date: 2010-01-01
    End date: 2012-07-05

Cimzia
    Dosage: 400 mug, unk
    Indication: Rheumatoid Arthritis
    Start date: 2012-02-01

Prednisone TAB
    Dosage: 8 mg, qd
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Diovan HCT; Nexium



Possible Methotrexate side effects in 83 year old male

Reported by a health professional (non-physician/pharmacist) from Ukraine on 2012-08-14

Patient: 83 year old male

Reactions: Weight Decreased, Lymphadenopathy, Soft Tissue Mass, Pelvic Pain, Blood Parathyroid Hormone Decreased, Constipation, Lymphoproliferative Disorder, Pleural Effusion, Lethargy, Decreased Appetite, Blood Alkaline Phosphatase Increased, Anaemia, Lymphopenia, Muscular Weakness, Multiple Fractures, Hypercalcaemia, Paraesthesia, Normochromic Normocytic Anaemia, Spinal Column Stenosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate

Other drugs received by patient: Omeprazole; Alfuzosin; Olmesartan Medoxomil; Folic Acid; Aspirin; Nsaid's; Lercanidipine; Simvastatin



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-08-09

Patient: female

Reactions: Enterocolitis Haemorrhagic, Gastrointestinal Haemorrhage, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ibruprofen
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-03-01
    End date: 2012-04-04

Prednisone TAB
    Dosage: 10 mg
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01

Methotrexate
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01
    End date: 2012-04-04

Clarithromycin
    Dosage: 1000 mg
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Fragmin
    Dosage: 5000 iu
    Indication: Prophylaxis
    Start date: 2012-03-01
    End date: 2012-04-04

Rocephin
    Dosage: 2 g
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Escitalopram
    Dosage: 10 mg
    Administration route: Oral

Other drugs received by patient: Pantoprazole; Calcimagon D3; Ramipril



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2012-08-08

Patient: female

Reactions: Anaemia, Concomitant Disease Aggravated, Dermatomyositis, Neutropenia, Trichiniasis, Thrombocytopenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Neoral
    Dosage: 150 mg, bid
    Administration route: Oral
    Start date: 2010-06-01
    End date: 2012-06-26

Methotrexate
    Dosage: 10 mg, qw
    Administration route: Oral
    Start date: 2011-06-01
    End date: 2012-06-26

Other drugs received by patient: Methotrexate Sodium; Folic Acid; Cortisone Acetate



Possible Methotrexate side effects in female

Reported by a physician from United States on 2012-08-08

Patient: female, weighing 59.0 kg (129.8 pounds)

Reactions: Weight Decreased, Night Sweats, Lymphadenopathy, Anaemia, Atrial Fibrillation, Osteopenia, Pyrexia, Fatigue, Pleural Effusion, non-Hodgkin's Lymphoma

Drug(s) suspected as cause:
Methotrexate
    Dosage: weekly
    Administration route: Oral

Methotrexate
    Administration route: Oral

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2009-08-12
    End date: 2012-05-01

Methotrexate
    Dosage: weekly
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2009-08-01

Other drugs received by patient: Ramipril; Lipitor; Metoprolol Tartrate; Aspirin



Possible Methotrexate side effects in 23 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-06

Patient: 23 year old female, weighing 60.0 kg (132.0 pounds)

Reactions: Abdominal Pain, Chills, Tachycardia, Anaemia, Pyrexia, Tremor, Malaise, Feeling Hot, Hypocalcaemia, Neutropenia, Blood Pressure Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin

Methotrexate

Doxorubicin HCL

Mepact
    Dosage: 3.4 mg, unk



Possible Methotrexate side effects in 24 year old female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: 24 year old female, weighing 51.0 kg (112.2 pounds)

Reactions: Abdominal Pain, Hyperkalaemia, Disseminated Intravascular Coagulation, Gastrointestinal Necrosis, Acidosis, Nephrolithiasis, Skin Discolouration, Ecchymosis, Clostridial Infection, Emphysema, White Blood Cell Count Decreased, Hypotension, Anaemia, Condition Aggravated, Soft Tissue Infection, Sepsis, Flank Pain, Colitis, Cardiac Arrest, Sinus Tachycardia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Sprycel
    Dosage: last dose on 26jun12
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Cytarabine
    Dosage: last dose:17jun12 route:intra ommya
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Vincristine Sulfate
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Filgrastim
    Dosage: last dose:18jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17
    End date: 2012-01-01

Leucovorin Calcium
    Dosage: last dose :21may12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Methotrexate
    Dosage: last dose:13jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Dexamethasone
    Dosage: last dose:16jun12
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Doxorubicin HCL
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Mesna
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Cyclophosphamide
    Dosage: last dose on 16jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Methylprednisolone
    Dosage: last dose:21may12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17



Possible Methotrexate side effects in male

Reported by a individual with unspecified qualification from United States on 2012-07-23

Patient: male, weighing 54.0 kg (118.8 pounds)

Reactions: White Blood Cell Count Decreased, Pneumonia, Chills, Anaemia, Febrile Neutropenia, Pyrexia, Oropharyngeal Pain, Fatigue, Respiratory Failure, Tachypnoea, Cough, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 135 mg

Methotrexate
    Dosage: 270 mg

Mercaptopurine
    Dosage: 8000 mg



Possible Methotrexate side effects in 73 year old female

Reported by a physician from Germany on 2012-07-20

Patient: 73 year old female, weighing 42.0 kg (92.4 pounds)

Reactions: Weight Decreased, Dyspnoea, Septic Encephalopathy, Anaemia, General Physical Health Deterioration, Epilepsy, Pneumococcal Sepsis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: once weekly, 7.5 mg once weekly
    Indication: Product Used FOR Unknown Indication
    Start date: 1994-01-01
    End date: 2012-06-01

Humira
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-03-08
    End date: 2012-05-01



Possible Methotrexate side effects in 68 year old female

Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-07-19

Patient: 68 year old female

Reactions: Enterocolitis Haemorrhagic, Gastrointestinal Haemorrhage, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rocephin
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Methotrexate
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01
    End date: 2012-04-04

Clarithromycin
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Ibuprofen Tablets
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-03-01
    End date: 2012-04-04

Escitalopram
    Indication: Product Used FOR Unknown Indication

Prednisone
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01

Other drugs received by patient: Calcimagon D3; Ramipril; Pantoprazole



Possible Methotrexate side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-17

Patient: male

Reactions: Anaemia, Acute Myeloid Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Idarubicin HCL
    Dosage: 12 mg/m2, unk
    Indication: Acute Promyelocytic Leukaemia

Tretinoin
    Dosage: 45 mg/m2, unk
    Indication: Acute Promyelocytic Leukaemia

Mitoxantrone
    Dosage: 10 mg/m2, unk
    Indication: Acute Promyelocytic Leukaemia

Methotrexate
    Dosage: 15 mg/m2, unk
    Indication: Acute Promyelocytic Leukaemia

Mercaptopurine
    Dosage: 50 mg, unk
    Indication: Acute Promyelocytic Leukaemia



Possible Methotrexate side effects in male

Reported by a physician from Italy on 2012-07-15

Patient: male

Reactions: Liver Function Test Abnormal, Anaemia, Thrombocytopenia, Leukopenia, Haemolysis

Drug(s) suspected as cause:
Methotrexate



Possible Methotrexate side effects in 68 year old female

Reported by a health professional (non-physician/pharmacist) from Switzerland on 2012-07-10

Patient: 68 year old female

Reactions: Enterocolitis Haemorrhagic, Gastrointestinal Haemorrhage, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Prednisone
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01

Ibuprofen Tablets
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-03-01
    End date: 2012-04-04

Escitalopram
    Indication: Product Used FOR Unknown Indication

Rocephin
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Clarithromycin
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Methotrexate
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01
    End date: 2012-04-04

Other drugs received by patient: Ramipril; Pantoprazole; Calcimagon D3



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-07-10

Patient: female

Reactions: Enterocolitis Haemorrhagic, Gastrointestinal Haemorrhage, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Escitalopram
    Dosage: 10 mg
    Administration route: Oral

Ibruprofen
    Administration route: Oral
    Indication: Back Pain
    Start date: 2012-03-01
    End date: 2012-04-04

Methotrexate
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01
    End date: 2012-04-04

Fragmin
    Dosage: 5000 iu
    Indication: Prophylaxis
    Start date: 2012-03-01
    End date: 2012-04-04

Clarithromycin
    Dosage: 1000 mg
    Administration route: Oral
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Rocephin
    Dosage: 2000 mg
    Indication: Pneumonia
    Start date: 2012-03-23
    End date: 2012-04-05

Prednisone
    Dosage: 10 mg
    Administration route: Oral
    Indication: Psoriasis
    Start date: 2005-08-01

Other drugs received by patient: Pantoprazole; Ramipril; Calcimagon D3



Possible Methotrexate side effects in 66 year old female

Reported by a physician from France on 2012-07-09

Patient: 66 year old female

Reactions: Renal Failure, Anaemia, Thrombocytopenia, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Irbesartan
    Administration route: Oral
    End date: 2012-05-11

Bisoprolol Fumarate
    Dosage: film-coated scored tablet
    Administration route: Oral
    End date: 2012-05-11

Methotrexate
    Dosage: methotrexate bellon 2.5 mg tablet
    Administration route: Oral
    Start date: 2012-04-19
    End date: 2012-05-11

Other drugs received by patient: Prednisone TAB; Lercanidipine; Insulatard NPH Human; Novorapid; Lasix



Possible Methotrexate side effects in 26 year old female

Reported by a physician from Japan on 2012-06-29

Patient: 26 year old female, weighing 41.0 kg (90.2 pounds)

Reactions: Enterocolitis Haemorrhagic, Cytomegalovirus Enterocolitis, Gastrointestinal Haemorrhage, Pleurisy, Anaemia, Platelet Count Decreased, Neutrophil Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate

Sprycel
    Dosage: 140mg,2per1d
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-03-01

Oncovin
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Cyclophosphamide
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Doxorubicin Hydrochloride
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-02-26
    End date: 2010-03-02

Other drugs received by patient: Diflucan; Cravit; Allopurinol; Primperan TAB; Lasix; Decadron; NEO-Minophagen C



Possible Methotrexate side effects in 33 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2012-06-26

Patient: 33 year old female

Reactions: Anaemia, Arthritis Bacterial, Tenosynovitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-28
    End date: 2012-04-10

Abatacept
    Dosage: blinded:13apr09 to 28sep09 open:29sep09-10apr12.
    Indication: Rheumatoid Arthritis
    Start date: 2009-04-13

Other drugs received by patient: Prednisolone; Shelcal; Ferrous Fumarate + Folic Acid; Hydroxychloroquine Sulfate; Azulfidine; Becosules; Folic Acid; Prednisolone; Acetaminophen



Possible Methotrexate side effects in 58 year old female

Reported by a physician from Canada on 2012-06-25

Patient: 58 year old female, weighing 73.8 kg (162.4 pounds)

Reactions: Dyspnoea, Pneumonia, Anaemia, Lung Infection, Muscular Weakness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2011-03-01
    End date: 2012-05-01

Arava
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2011-01-01

Cimzia
    Indication: Rheumatoid Arthritis
    Start date: 2012-04-18
    End date: 2012-05-01

Other drugs received by patient: Diltiazem Hydrocholoride; Diclofenac Sodium; Atacand



Possible Methotrexate side effects in 16 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-25

Patient: 16 year old male

Reactions: Blood Bilirubin Increased, White Blood Cell Count Decreased, Acute Pulmonary Oedema, Alanine Aminotransferase Increased, Anaemia, Hepatic Failure, Toxic Epidermal Necrolysis, Bicytopenia, Multi-Organ Failure, Aspartate Aminotransferase Increased, Platelet Count Decreased, Asthenia, Hepatosplenomegaly, Hepatitis Fulminant

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 104 mg, single intake, unknown, intravenous
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-05

Cyclophosphamide
    Dosage: 432 mg milligram(s) (1 day) intravenous (not otherwise specified)
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-05
    End date: 2012-02-07

Vincristine Sulfate
    Dosage: 2 mg, single intake (unknown) intravenous drip
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-04

Methotrexate
    Dosage: 5193 mg, single intake (unknown) 15 mg milligram(s) (unknown) intravenous drip intrathecal
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-04

(Mabthera)
    Dosage: 650 mg, single intake (unknown) intravenous (not otherwise specified)
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-02-02

Other drugs received by patient: Lasix; Prednisolone



Possible Methotrexate side effects in male

Reported by a individual with unspecified qualification from Italy on 2012-06-18

Patient: male

Reactions: Epstein-Barr Virus Infection, Diarrhoea, Anaemia, Sepsis, Cytomegalovirus Infection, Neutropenia, Thrombocytopenia, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Burkitt's Lymphoma

Vincristine Sulfate
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Burkitt's Lymphoma

Cisplatin
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Burkitt's Lymphoma

Etoposide
    Indication: Burkitt's Lymphoma

Mabthera
    Indication: Burkitt's Lymphoma

Doxorubicin Hydrochloride
    Indication: Burkitt's Lymphoma



Possible Methotrexate side effects in male

Reported by a physician from Italy on 2012-06-14

Patient: male

Reactions: Epstein-Barr Virus Infection, Anaemia, Cytomegalovirus Infection, Neutropenia, Thrombocytopenia, Disease Progression, Infection

Drug(s) suspected as cause:
Carmustine
    Indication: Burkitt's Lymphoma

Carboplatin
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Lymphoma

Etoposide
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Burkitt's Lymphoma

Vincristine
    Indication: Burkitt's Lymphoma

Melphalan Hydrochloride
    Indication: Burkitt's Lymphoma

Radiotherapy
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Cisplatin
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Burkitt's Lymphoma

Ifosfamide
    Indication: Burkitt's Lymphoma

Granulocyte Colony Stimulating Factor
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Burkitt's Lymphoma

Unknown Medication
    Dosage: antimicrobial prophylaxis
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Unknown Medication



Possible Methotrexate side effects in female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-06-13

Patient: female, weighing 63.0 kg (138.6 pounds)

Reactions: Stomatitis, Diabetes Mellitus, Hyperkalaemia, Extrasystoles, Anaemia, Hyperglycaemia, Tachycardia, Hypokalaemia, Adrenal Disorder, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Remicade
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-04

Methotrexate
    Indication: Product Used FOR Unknown Indication

Methotrexate

Other drugs received by patient: Atacand HCT; Diuretics



Possible Methotrexate side effects in 50 year old female

Reported by a consumer/non-health professional from Colombia on 2012-06-11

Patient: 50 year old female

Reactions: Back Pain, Increased Upper Airway Secretion, Anaemia, Cough

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Etanercept
    Dosage: 50 mg, qwk
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-06

Methotrexate
    Dosage: 6 capsules every 8 days orally (all in one)
    Administration route: Oral
    Indication: Rheumatoid Arthritis
    Start date: 2012-01-06

Other drugs received by patient: Levothyroxine Sodium; Prednisolone; Acetaminophen; Diclofenac Sodium; Albuterol



Possible Methotrexate side effects in 33 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2012-06-11

Patient: 33 year old female

Reactions: Anaemia, Arthritis Bacterial, Tenosynovitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-28
    End date: 2012-04-10

Abatacept
    Dosage: blinded:13apr09 to 28sep09 open:29sep09-10apr12.
    Indication: Rheumatoid Arthritis
    Start date: 2009-04-13

Other drugs received by patient: Azulfidine; Prednisolone; Shelcal; Hydroxychloroquine Sulfate; Acetaminophen; Ferrous Fumarate + Folic Acid; Becosules; Folic Acid; Prednisolone



Possible Methotrexate side effects in 17 year old female

Reported by a physician from United States on 2012-06-08

Patient: 17 year old female, weighing 47.6 kg (104.7 pounds)

Reactions: Blood Bilirubin Increased, Pyrexia, Caecitis, Loss of Consciousness, Oedema Peripheral, Pulmonary Oedema, Hypocalcaemia, Acute Respiratory Distress Syndrome, Melaena, Hypertriglyceridaemia, Epistaxis, Dysphagia, Anaemia, Hyperglycaemia, General Physical Health Deterioration, Eating Disorder, Tremor, Cerebral Infarction, Depressed Level of Consciousness, Neutropenia, Confusional State, Dyskinesia, Somnolence, Splenic Infarction, Hypokalaemia, Pleural Effusion, White Blood Cell Count Decreased, Cerebrovascular Accident, Ascites, Diarrhoea, Hypophagia, Hypoalbuminaemia, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 60mgm2 cyclic
    Administration route: Oral
    Indication: T-Cell Type Acute Leukaemia

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Cyclophosphamide
    Dosage: 1000mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Methotrexate
    Indication: T-Cell Type Acute Leukaemia

Oncaspar
    Indication: T-Cell Type Acute Leukaemia

Nelarabine
    Dosage: 650mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-04-13

Cytarabine
    Dosage: 75mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Dalteparin Sodium
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Nystatin; Lansoprazole; Insulin Aspart; Piperacillin and Tazobactam; Vancomycin; Voriconazole



Possible Methotrexate side effects in 26 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-06

Patient: 26 year old female

Reactions: Hypovolaemic Shock, Abdominal Pain, Portal Hypertension, Anaemia, Oesophageal Varices Haemorrhage, Haematemesis, Abdominal Tenderness, Liver Disorder, Ascites, Fibrosis, Hepatic Cirrhosis

Drug(s) suspected as cause:
Methotrexate
    Dosage: 200 mg, qw
    Indication: Rheumatoid Arthritis

Hydroxychloroquine Sulfate
    Dosage: 400 mg, qd
    Indication: Rheumatoid Arthritis



Possible Methotrexate side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-06-05

Patient: 75 year old male

Reactions: Back Pain, Pneumonia Aspiration, Drug Ineffective, Anaemia, Lumbar Vertebral Fracture, Respiratory Failure, Pancreatitis, Trichosporon Infection, Neutrophil Count Decreased

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 10 mg, qw
    Indication: Rheumatoid Arthritis

Prednisolone
    Dosage: 30 mg, per day
    Start date: 2009-02-01

Prednisolone
    Dosage: 5 mg, day
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Micafungin; Antibacterials FOR Systemic USE; Fluconazole; Sulfamethoxazole + Trimethoprim; Albumin (Human); Ampicillin and Sulbactam; Meropenem; Ciprofloxacin; Furosemide; Micafungin



Possible Methotrexate side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-05

Patient: male, weighing 102.6 kg (225.7 pounds)

Reactions: Cardio-Respiratory Arrest, Respiratory Failure, Anaemia, Troponin I Increased, Thrombocytopenia, Infection

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 1600 mg, cyclic
    End date: 2011-07-28

Adriamycin PFS
    Dosage: 101 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-07-05
    End date: 2011-07-05

Rituximab
    Dosage: 750 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-07-01
    End date: 2011-07-26

Methotrexate
    Dosage: 400 mg, cyclic
    Indication: Mantle Cell Lymphoma
    End date: 2011-07-27

Cytarabine
    Dosage: 6 g, cyclic
    Indication: Mantle Cell Lymphoma
    End date: 2011-07-30

Dexamethasone
    Dosage: 40 mg, cyclic
    Indication: Mantle Cell Lymphoma

Dexamethasone
    Dosage: 20 unk, unk
    Administration route: Oral
    End date: 2011-07-15

Vincristine
    Dosage: 2 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-07-05
    End date: 2011-07-12

Velcade
    Dosage: 2.6 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-07-01
    End date: 2011-07-26

Cyclophosphamide
    Dosage: 603 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-07-02
    End date: 2011-07-04

Other drugs received by patient: Filgrastim; Ferrous Sulfate TAB; Heparin; Senokot; Triamcinolone Acetonide; Compazine; Ciprofloxacin; Fluconazole; Omeprazole; Mesna; Prevident; Valtrex; Vitamin C / 00008001 /; Methylprednisolone; Periogard; Ultram; Vitamin D



Possible Methotrexate side effects in 16 year old female

Reported by a pharmacist from United States on 2012-06-01

Patient: 16 year old female, weighing 48.5 kg (106.7 pounds)

Reactions: Abdominal Pain, Post Procedural Complication, Myelodysplastic Syndrome, Neoplasm Progression, Disease Progression, Blast Cells Present, Postoperative Wound Complication, Medical Device Complication, Fistula, Anaemia, Acute Myeloid Leukaemia, Febrile Neutropenia, Renal Failure, Impaired Healing, Joint Swelling, Arthralgia, Sepsis, Treatment Failure, Lung Infiltration, Deep Vein Thrombosis

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Remicade
    Dosage: infliximab 250mg iv x 3
    Indication: Colitis Ulcerative
    Start date: 2010-10-06

Remicade
    Dosage: infliximab 250mg iv x 3
    Indication: Colitis Ulcerative
    Start date: 2010-10-22

Remicade
    Dosage: infliximab 250mg iv x 3
    Indication: Colitis Ulcerative
    Start date: 2010-10-19

Methotrexate
    Dosage: methotrexate 25mg sc x 1
    Indication: Colitis Ulcerative
    Start date: 2010-09-30

Other drugs received by patient: Humira; Mesalamine; Prednisone TAB; Adalimumab



Possible Methotrexate side effects in 33 year old female

Reported by a health professional (non-physician/pharmacist) from India on 2012-05-31

Patient: 33 year old female

Reactions: Anaemia, Arthritis Bacterial, Tenosynovitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Abatacept
    Dosage: blinded:13apr09 to 28sep09 open:29sep09-10apr12.
    Indication: Rheumatoid Arthritis
    Start date: 2009-04-13

Methotrexate
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-28
    End date: 2012-04-10

Other drugs received by patient: Azulfidine; Ferrous Fumarate + Folic Acid; Hydroxychloroquine Sulfate; Becosules; Folic Acid; Shelcal; Prednisolone; Prednisolone; Acetaminophen



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