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Mesna (Mesna) - Death - Suspected Cause - Side Effect Reports

 
 



Index of reports > Death (29)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Mesna death. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Mesna side effects in female

Reported by a physician from Israel on 2012-08-08

Patient: female, weighing 73.5 kg (161.7 pounds)

Reactions: General Physical Health Deterioration

Adverse event resulted in: death

Drug(s) suspected as cause:
Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-17

Etoposide
    Dosage: 90mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-07-17

Ifosfamide
    Dosage: 1200mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-07-17

Dexamethasone
    Dosage: 40mg every 3 weeks
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-18

Cytarabine
    Dosage: 4mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-19

Cisplatin
    Dosage: 100mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-18

Methotrexate
    Dosage: 30mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-07-17

Mesna
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-07-17



Possible Mesna side effects in 24 year old female

Reported by a consumer/non-health professional from United States on 2012-07-30

Patient: 24 year old female, weighing 51.0 kg (112.2 pounds)

Reactions: Abdominal Pain, Hyperkalaemia, Disseminated Intravascular Coagulation, Gastrointestinal Necrosis, Acidosis, Nephrolithiasis, Skin Discolouration, Ecchymosis, Clostridial Infection, Emphysema, White Blood Cell Count Decreased, Hypotension, Anaemia, Condition Aggravated, Soft Tissue Infection, Sepsis, Flank Pain, Colitis, Cardiac Arrest, Sinus Tachycardia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Sprycel
    Dosage: last dose on 26jun12
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Cytarabine
    Dosage: last dose:17jun12 route:intra ommya
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Vincristine Sulfate
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Filgrastim
    Dosage: last dose:18jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17
    End date: 2012-01-01

Leucovorin Calcium
    Dosage: last dose :21may12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Methotrexate
    Dosage: last dose:13jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Dexamethasone
    Dosage: last dose:16jun12
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Doxorubicin HCL
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Mesna
    Dosage: last dose:17jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Cyclophosphamide
    Dosage: last dose on 16jun12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17

Methylprednisolone
    Dosage: last dose:21may12
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-05-17



Possible Mesna side effects in male

Reported by a pharmacist from United States on 2012-06-29

Patient: male, weighing 21.3 kg (46.9 pounds)

Reactions: B-Cell Lymphoma, Hypotension, Alanine Aminotransferase Increased, Pancytopenia, Roseolovirus Test Positive, Aspartate Aminotransferase Increased, Venoocclusive Liver Disease, Acute Respiratory Distress Syndrome, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Fludarabine Phosphate
    Indication: Product Used FOR Unknown Indication

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: B-Cell Lymphoma
    Start date: 2011-12-27
    End date: 2012-01-16

Mesna
    Indication: Product Used FOR Unknown Indication

Cyclophosphamide
    Indication: Product Used FOR Unknown Indication



Possible Mesna side effects in male

Reported by a physician from Poland on 2012-06-22

Patient: male, weighing 58.0 kg (127.6 pounds)

Reactions: Pneumonia, Circulatory Collapse, Altered State of Consciousness

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Etoposide
    Dosage: 96mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Mesna
    Dosage: 128mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Cytosar-U
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-17

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16

Ifosfamide
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Other drugs received by patient: Zokzid; Metronidazole; Albuminar-20; Sodium Chloride 0.9%; Diflucan; Meropenem; 5% Glucose; Furosemide



Possible Mesna side effects in male

Reported by a physician from Poland on 2012-06-19

Patient: male, weighing 58.0 kg (127.6 pounds)

Reactions: Pneumonia, Circulatory Collapse, Altered State of Consciousness

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Etoposide
    Dosage: 96mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Cytosar-U
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-17

Ifosfamide
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Mesna
    Dosage: 128mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16

Other drugs received by patient: Furosemide; Albuminar-20; Zokzid; Diflucan; 5% Glucose; Meropenem; Metronidazole; Sodium Chloride 0.9%



Possible Mesna side effects in male

Reported by a physician from Poland on 2012-06-15

Patient: male, weighing 58.0 kg (127.6 pounds)

Reactions: Pneumonia, Blood PH Decreased, Haemoglobin Decreased, Haematocrit Decreased, Gamma-Glutamyltransferase Increased, RED Blood Cell Count Decreased, Circulatory Collapse, Platelet Count Decreased, Altered State of Consciousness

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Etoposide
    Dosage: 96mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Cytosar-U
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-17

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16

Mesna
    Dosage: 128mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Ifosfamide
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Other drugs received by patient: Diflucan; Albuminar-20; Metronidazole; Zokzid; Meropenem; 5% Glucose; Furosemide; Sodium Chloride 0.9%



Possible Mesna side effects in male

Reported by a physician from Poland on 2012-06-14

Patient: male, weighing 58.0 kg (127.6 pounds)

Reactions: Pneumonia, Circulatory Collapse, Altered State of Consciousness

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Ifosfamide
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Etoposide
    Dosage: 96mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Mesna
    Dosage: 128mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-20

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16

Cytosar-U
    Dosage: 1600mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma
    Start date: 2012-05-16
    End date: 2012-05-17

Other drugs received by patient: Metronidazole; Meropenem; Furosemide; Zokzid; Diflucan; Sodium Chloride 0.9%; Albuminar-20; 5% Glucose



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from Croatia (Local Name: Hrvatska) on 2012-06-12

Patient:

Reactions: Mucosal Inflammation, Multi-Organ Failure, Tumour Lysis Syndrome, Condition Aggravated, Febrile Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Leukaemia

Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Leukaemia

Leucovorin Calcium
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Prednisone TAB
    Dosage: days 1-5
    Indication: Burkitt's Leukaemia

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Leukaemia

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Prednisone TAB
    Dosage: days 1-5
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Prophylaxis

Methylprednisolone
    Indication: Prophylaxis

Rituximab
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Leucovorin Calcium
    Indication: Burkitt's Leukaemia

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Prophylaxis

Mesna
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Mesna
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Blood Products; Acyclovir; Antibiotics; Neupogen



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from Croatia (Local Name: Hrvatska) on 2012-06-08

Patient:

Reactions: Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Prophylaxis

Prednisone
    Dosage: days 1-5
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Leukaemia

Mesna
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Prophylaxis

Mesna
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Leucovorin Calcium
    Indication: Burkitt's Leukaemia

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Lymphoma

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Leukaemia

Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Leukaemia

Prednisone
    Dosage: days 1-5
    Indication: Burkitt's Leukaemia

Leucovorin Calcium
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Methotrexate
    Indication: Prophylaxis

Other drugs received by patient: Neupogen; Acyclovir; Antibiotics; Blood Products



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from Croatia (Local Name: Hrvatska) on 2012-06-08

Patient:

Reactions: Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Leukaemia

Methylprednisolone
    Indication: Prophylaxis

Mesna
    Indication: Burkitt's Leukaemia

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Cytarabine
    Indication: Prophylaxis

Rituximab
    Indication: Burkitt's Leukaemia

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Leukaemia

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Prophylaxis

Mesna
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Leukaemia

Prednisone
    Dosage: days 1-5
    Indication: Burkitt's Leukaemia

Prednisone
    Dosage: days 1-5
    Indication: Burkitt's Lymphoma

Leucovorin Calcium
    Indication: Burkitt's Leukaemia

Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Leukaemia

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Leucovorin Calcium
    Indication: Burkitt's Lymphoma

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Lymphoma

Other drugs received by patient: Neupogen; Blood Products; Acyclovir; Antibiotics



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from Croatia (Local Name: Hrvatska) on 2012-06-08

Patient:

Reactions: Multi-Organ Failure, Tumour Lysis Syndrome

Adverse event resulted in: death

Drug(s) suspected as cause:
Etoposide
    Dosage: days 4, 5
    Indication: Burkitt's Lymphoma

Methotrexate
    Dosage: on day 1 with folinic acid rescue
    Indication: Burkitt's Lymphoma

Radiation Therapy NOS
    Dosage: 30-36 gy
    Indication: Burkitt's Lymphoma

Prednisone
    Dosage: days 1-5
    Indication: Burkitt's Lymphoma

Ifosfamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Leucovorin Calcium
    Indication: Burkitt's Lymphoma

Cytarabine
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Prophylaxis

Mesna
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Dosage: on days 4, 5
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Vincristine
    Dosage: on day 1
    Indication: Burkitt's Lymphoma

Cytarabine
    Indication: Prophylaxis

Dexamethasone
    Dosage: on days 1-5
    Indication: Burkitt's Lymphoma

Methylprednisolone
    Indication: Prophylaxis

Other drugs received by patient: Neupogen; Blood Products; Acyclovir; Antibiotics



Possible Mesna side effects in 50 year old male

Reported by a physician from Greece on 2012-05-31

Patient: 50 year old male

Reactions: Multi-Organ Failure, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Ifosfamide
    Indication: Hodgkin's Disease

Doxorubicin HCL
    Indication: Hodgkin's Disease

Etoposide
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Indication: Hodgkin's Disease

Vinblastine Sulfate
    Indication: Hodgkin's Disease

Mesna
    Indication: Hodgkin's Disease

Mitoxantrone Hydrochloride

Dacarbazine
    Indication: Hodgkin's Disease



Possible Mesna side effects in male

Reported by a consumer/non-health professional from United States on 2012-05-25

Patient: male, weighing 21.3 kg (46.9 pounds)

Reactions: B-Cell Lymphoma, Hypotension, Alanine Aminotransferase Increased, Pancytopenia, Roseolovirus Test Positive, Aspartate Aminotransferase Increased, Venoocclusive Liver Disease, Acute Respiratory Distress Syndrome, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Mesna
    Indication: Product Used FOR Unknown Indication

Fludarabine Phosphate
    Indication: Product Used FOR Unknown Indication

Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: B-Cell Lymphoma
    Start date: 2011-12-27
    End date: 2012-01-06

Cytoxan
    Indication: Product Used FOR Unknown Indication



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from China on 2012-05-10

Patient:

Reactions: Hypersensitivity, Neurotoxicity, Off Label Use, Hepatotoxicity, Granulocytopenia, Bone Marrow Failure, White Blood Cell Count Decreased, Gastrointestinal Toxicity, Nephropathy Toxic, Urinary Tract Infection, Anaemia, Soft Tissue Infection, Acute Lymphocytic Leukaemia, Sepsis, Platelet Count Decreased, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Cytarabine
    Indication: Acute Lymphocytic Leukaemia

Mesna
    Indication: Acute Myeloid Leukaemia

Methotrexate
    Indication: non-Hodgkin's Lymphoma

Vincristine
    Indication: non-Hodgkin's Lymphoma

Vincristine
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Indication: Acute Lymphocytic Leukaemia

Mesna
    Indication: non-Hodgkin's Lymphoma

Vindesine
    Indication: Acute Lymphocytic Leukaemia

Vindesine
    Indication: non-Hodgkin's Lymphoma

Doxorubicin HCL
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: non-Hodgkin's Lymphoma

Cyclophosphamide
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Indication: non-Hodgkin's Lymphoma

Doxorubicin HCL
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone TAB
    Indication: non-Hodgkin's Lymphoma

Dexamethasone TAB
    Indication: Acute Lymphocytic Leukaemia

Other drugs received by patient: Leucovorin Calcium



Possible Mesna side effects in 50 year old male

Reported by a physician from Greece on 2012-05-02

Patient: 50 year old male

Reactions: Multi-Organ Failure, Toxicity To Various Agents

Adverse event resulted in: death

Drug(s) suspected as cause:
Mitoxantrone Hydrochloride

Etoposide
    Indication: Hodgkin's Disease

Mesna
    Indication: Hodgkin's Disease

Ifosfamide
    Indication: Hodgkin's Disease

Bleomycin
    Indication: Hodgkin's Disease

Vinblastine
    Indication: Hodgkin's Disease

Dacarbazine
    Indication: Hodgkin's Disease

Doxorubicin HCL
    Indication: Hodgkin's Disease



Possible Mesna side effects in

Reported by a physician from Norway on 2012-02-29

Patient:

Reactions: Off Label Use, Nephropathy Toxic

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL

Doxorubicin HCL
    Indication: Sarcoma

Ifosfamide
    Indication: Sarcoma

Ifosfamide

Ifosfamide

Mesna

Doxorubicin HCL

Mesna
    Indication: Sarcoma

Mesna

Radiation Therapy NOS
    Indication: Sarcoma



Possible Mesna side effects in

Reported by a physician from Norway on 2012-02-29

Patient:

Reactions: Off Label Use, Blood Creatinine Abnormal

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL

Ifosfamide
    Indication: Sarcoma

Radiation Therapy NOS
    Indication: Sarcoma

Doxorubicin HCL

Ifosfamide

Mesna

Mesna
    Indication: Sarcoma

Ifosfamide

Doxorubicin HCL
    Indication: Sarcoma

Mesna



Possible Mesna side effects in 61 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-02-23

Patient: 61 year old female

Reactions: Urinary Tract Infection, Encephalopathy, Meningitis, Septic Shock, Renal Failure Acute

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Zofran
    Dosage: 8mg/day
    Start date: 2011-12-05
    End date: 2011-12-06

Solu-Medrol
    Dosage: 40mg/day
    Indication: Chemotherapy
    Start date: 2011-12-05
    End date: 2011-12-06

Ifosfamide
    Dosage: 4160mg/day
    Indication: Chemotherapy
    Start date: 2011-12-05
    End date: 2011-12-06

Mesna
    Dosage: 1300 mg, 3x/day
    Indication: Chemotherapy
    Start date: 2011-12-05
    End date: 2011-12-06

Emend
    Dosage: 80mg/day
    Administration route: Oral
    Indication: Chemotherapy
    Start date: 2011-12-05
    End date: 2011-12-06

Other drugs received by patient: Lyrica; Duragesic-100; Oxycodone HCL; Lyrica



Possible Mesna side effects in 60 year old male

Reported by a physician from Korea, Democratic People's Republic of on 2012-02-10

Patient: 60 year old male

Reactions: Leukoencephalopathy

Adverse event resulted in: death

Drug(s) suspected as cause:
Methotrexate

Etoposide
    Indication: Lymphoma

Prednisolone
    Dosage: 300 mg
    Administration route: Oral
    Indication: Lymphoma

Ifosfamide
    Indication: Lymphoma

Mesna
    Indication: Lymphoma

Methotrexate
    Indication: Lymphoma

Hydrocortisone
    Indication: Lymphoma

Cytarabine
    Indication: Lymphoma



Possible Mesna side effects in 59 year old female

Reported by a physician from Korea, Democratic People's Republic of on 2012-02-10

Patient: 59 year old female

Reactions: Leukoencephalopathy

Adverse event resulted in: death

Drug(s) suspected as cause:
Prednisolone
    Dosage: 300 mg
    Administration route: Oral
    Indication: Lymphoma

Methotrexate

Cytarabine
    Indication: Lymphoma

Hydrocortisone
    Indication: Lymphoma

Ifosfamide
    Indication: Lymphoma

Methotrexate
    Indication: Lymphoma

Etoposide
    Indication: Lymphoma

Mesna
    Indication: Lymphoma



Possible Mesna side effects in 65 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2012-01-23

Patient: 65 year old male

Reactions: Multi-Organ Failure, Lung Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Busulfan
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-12-02
    End date: 2011-12-04

Cyclophosphamide
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-12-05
    End date: 2011-12-06

Thiotepa
    Indication: Bone Marrow Conditioning Regimen
    Start date: 2011-11-29
    End date: 2011-12-01

Mesna
    Indication: Product Used FOR Unknown Indication
    Start date: 2011-12-05
    End date: 2011-12-06

Other drugs received by patient: Clonazepam



Possible Mesna side effects in 36 year old male

Reported by a health professional (non-physician/pharmacist) from France on 2011-12-09

Patient: 36 year old male

Reactions: Cardiac Tamponade, Hypotension, Tachycardia, Diastolic Dysfunction, Myopericarditis, Systolic Dysfunction, Sepsis, Cardiac Arrest, Anuria

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Metoclopramide
    Dosage: 3 unit
    Start date: 2011-03-05
    End date: 2011-03-06

Gentamicin Sulfate
    Dosage: 300 mg, unk
    Administration route: Oral
    Start date: 2011-03-02
    End date: 2011-03-06

Cyclophosphamide
    Dosage: 3200 mg, unk
    Start date: 2011-03-01
    End date: 2011-03-04

Fondaparinux Sodium

Carboplatin
    Dosage: 899 mg, unk
    Start date: 2011-03-01
    End date: 2011-03-04

Morphine
    Dosage: unk
    Start date: 2011-03-05
    End date: 2011-03-06

Amifostine
    Dosage: 2 unit
    Start date: 2011-03-01
    End date: 2011-03-04

Mesna
    Dosage: 800 mg, unk
    Start date: 2011-03-01
    End date: 2011-03-04

Etoposide
    Dosage: 900 mg, unk
    Start date: 2011-03-01
    End date: 2011-03-04

Acyclovir
    Dosage: 750 mg, unk
    Start date: 2011-03-05
    End date: 2011-03-06

Amikacin
    Dosage: 1300 mg, unk
    Start date: 2011-03-04
    End date: 2011-03-05

Piperacillin and Tazobactam
    Dosage: 12 g, unk
    Start date: 2011-03-04
    End date: 2011-03-06

Other drugs received by patient: Prednisolone; Levetiracetam; Clonazepam; Esomeprazole; Pregabalin



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-31

Patient:

Reactions: Sudden Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Lymphoma

Doxorubicin HCL

Cyclophosphamide

Cyclophosphamide

Bleomycin Sulfate
    Indication: Lymphoma

Bleomycin Sulfate

Methotrexate
    Indication: Lymphoma

Cytarabine
    Indication: Lymphoma

Doxorubicin HCL

Cyclophosphamide
    Indication: Lymphoma

Eldisine

Bleomycin Sulfate

Cytarabine

Methotrexate

Ifosfamide

Mesna

Eldisine

Prednisone
    Administration route: Oral
    Indication: Lymphoma

Ifosfamide
    Indication: Lymphoma

Cyclophosphamide

Mesna

Eldisine
    Indication: Lymphoma

Eldisine

Methotrexate

Etoposide
    Indication: Lymphoma

Ifosfamide

Doxorubicin HCL

Mesna
    Indication: Lymphoma

Mesna

Bleomycin Sulfate

Ifosfamide

Other drugs received by patient: Neupogen



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-31

Patient:

Reactions: Completed Suicide

Adverse event resulted in: death

Drug(s) suspected as cause:
Cyclophosphamide
    Indication: Lymphoma

Cyclophosphamide

Eldisine

Eldisine

Ifosfamide
    Indication: Lymphoma

Cyclophosphamide

Cyclophosphamide

Mesna

Ifosfamide

Etoposide

Cytarabine
    Indication: Lymphoma

Cytarabine

Eldisine

Bleomycin Sulfate
    Indication: Lymphoma

Bleomycin Sulfate

Etoposide

Mesna

Eldisine
    Indication: Lymphoma

Bleomycin Sulfate

Methotrexate

Doxorubicin HCL

Mesna

Bleomycin Sulfate

Ifosfamide

Ifosfamide

Etoposide
    Indication: Lymphoma

Etoposide

Cytarabine

Doxorubicin HCL
    Indication: Lymphoma

Doxorubicin HCL

Doxorubicin HCL

Mesna
    Indication: Lymphoma

Prednisone
    Administration route: Oral
    Indication: Lymphoma

Methotrexate
    Indication: Lymphoma

Methotrexate

Cytarabine

Other drugs received by patient: Neupogen



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-31

Patient:

Reactions: Cardiac Failure

Adverse event resulted in: death

Drug(s) suspected as cause:
Eldisine
    Indication: Lymphoma

Eldisine

Bleomycin Sulfate

Cyclophosphamide

Mesna

Methotrexate
    Indication: Lymphoma

Mesna
    Indication: Lymphoma

Prednisone
    Administration route: Oral
    Indication: Lymphoma

Etoposide
    Indication: Lymphoma

Ifosfamide

Doxorubicin HCL

Doxorubicin HCL

Doxorubicin HCL

Cyclophosphamide
    Indication: Lymphoma

Cyclophosphamide

Mesna

Methotrexate

Ifosfamide
    Indication: Lymphoma

Ifosfamide

Eldisine

Bleomycin Sulfate

Bleomycin Sulfate

Cytarabine
    Indication: Lymphoma

Bleomycin Sulfate
    Indication: Lymphoma

Ifosfamide

Doxorubicin HCL
    Indication: Lymphoma

Cyclophosphamide

Mesna

Eldisine

Cytarabine

Methotrexate

Other drugs received by patient: Leucovorin Calcium; Neupogen



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-31

Patient:

Reactions: Toxicity To Various Agents, Infection

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL

Cyclophosphamide

Mesna

Eldisine
    Indication: Lymphoma

Eldisine

Eldisine

Bleomycin Sulfate

Methotrexate
    Indication: Lymphoma

Bleomycin Sulfate

Doxorubicin HCL
    Indication: Lymphoma

Eldisine

Bleomycin Sulfate
    Indication: Lymphoma

Cyclophosphamide

Mesna

Prednisone
    Administration route: Oral
    Indication: Lymphoma

Cyclophosphamide
    Indication: Lymphoma

Mesna
    Indication: Lymphoma

Mesna

Bleomycin Sulfate

Doxorubicin HCL

Doxorubicin HCL

Cyclophosphamide

Other drugs received by patient: Neupogen



Possible Mesna side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-31

Patient:

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Eldisine

Eldisine
    Indication: Lymphoma

Ifosfamide
    Indication: Lymphoma

Doxorubicin HCL

Doxorubicin HCL

Eldisine

Prednisone
    Administration route: Oral
    Indication: Lymphoma

Bleomycin Sulfate

Cytarabine
    Indication: Lymphoma

Cyclophosphamide

Mesna

Mesna

Eldisine

Bleomycin Sulfate

Methotrexate
    Indication: Lymphoma

Etoposide
    Indication: Lymphoma

Ifosfamide

Doxorubicin HCL

Cytarabine

Cyclophosphamide
    Indication: Lymphoma

Cyclophosphamide

Cyclophosphamide

Mesna
    Indication: Lymphoma

Mesna

Doxorubicin HCL
    Indication: Lymphoma

Bleomycin Sulfate
    Indication: Lymphoma

Bleomycin Sulfate

Methotrexate

Methotrexate

Ifosfamide

Ifosfamide

Other drugs received by patient: Leucovorin Calcium; Neupogen



Possible Mesna side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-25

Patient: female

Reactions: Death, Febrile Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Sarcoma Uterus

Mesna
    Indication: Sarcoma Uterus

Cisplatin
    Indication: Sarcoma Uterus

Ifosfamide
    Indication: Sarcoma Uterus

Lenograstim
    Indication: Sarcoma Uterus



Possible Mesna side effects in female

Reported by a health professional (non-physician/pharmacist) from France on 2011-10-24

Patient: female

Reactions: Febrile Neutropenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Indication: Sarcoma Uterus

Lenograstim
    Indication: Sarcoma Uterus

Doxorubicin HCL
    Indication: Sarcoma Uterus

Ifosfamide
    Indication: Sarcoma Uterus

Mesna
    Indication: Sarcoma Uterus

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