DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Mesna (Mesna) - Pyrexia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pyrexia (13)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Mesna where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Mesna side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16

Patient: female, weighing 87.8 kg (193.2 pounds)

Reactions: Neuropathy Peripheral, Upper Respiratory Tract Infection, Urinary Tract Infection, Pleural Effusion, Pyrexia, Leukocytosis, Sinusitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 40 mg, unk
    Administration route: Oral
    Indication: Mantle Cell Lymphoma

Cytarabine
    Dosage: 1.87 g, cyclic
    Indication: Mantle Cell Lymphoma

Velcade
    Dosage: 0.7 mg/m2, cyclic
    Start date: 2012-03-19

Vincristine
    Dosage: 2 mg, cyclic
    Indication: Mantle Cell Lymphoma

Velcade
    Dosage: 2.77 mg, cyclic
    Indication: Mantle Cell Lymphoma
    Start date: 2011-12-31

Velcade
    Dosage: 0.7 mg/m2, cyclic

Velcade
    Dosage: 0.7 mg/m2, cyclic
    Start date: 2012-02-26

Rituximab
    Dosage: 1 mg/m2, cyclic
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Indication: Mantle Cell Lymphoma

Doxorubicin Hydrochloride
    Dosage: 50 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Methotrexate
    Indication: Mantle Cell Lymphoma

Mesna
    Dosage: 600 mg/m2, unk
    Indication: Mantle Cell Lymphoma

Other drugs received by patient: Sennosides A+B; Nystatin; Diphenhydramine Hydrochloride; Neupogen; Fluconazole; Zofran; Valtrex; Sodium Chloride; Meperidine HCL; Potassium Chloride; Leucovorin Calcium; Zofran; Sodium Chloride; Sodium Chloride; Sodium Chloride; Heparin; Leucovorin Calcium; Allopurinol; Lovenox; Morphine; Senokot; Cipro / 00042702 /; Lovenox; Prednisolone Acetate; Stomatologicals, Mouth Preparations; Tramadol; Sodium Bicarbonate



Possible Mesna side effects in 6 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-07

Patient: 6 year old female

Reactions: Off Label Use, Gastrointestinal Ischaemia, Pyrexia, Leukopenia, Hodgkin's Disease

Drug(s) suspected as cause:
Vinorelbine
    Indication: Hodgkin's Disease

Vinorelbine
    Indication: Diffuse Large B-Cell Lymphoma

Ifosfamide
    Indication: Hodgkin's Disease

Ifosfamide
    Indication: Diffuse Large B-Cell Lymphoma

Mesna
    Indication: Diffuse Large B-Cell Lymphoma

Mesna
    Indication: Hodgkin's Disease

Filgrastim (Filgrastim) [ Regimen #1
    Indication: Diffuse Large B-Cell Lymphoma

Filgrastim (Filgrastim) [ Regimen #1
    Indication: Hodgkin's Disease



Possible Mesna side effects in female

Reported by a individual with unspecified qualification from France on 2012-04-09

Patient: female

Reactions: Encephalopathy, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ifosfamide
    Dosage: daily day1-day3
    Indication: Angiosarcoma
    Start date: 2012-02-09
    End date: 2012-02-11

Mesna
    Start date: 2012-02-09
    End date: 2012-02-09

Emend
    Dosage: daily day1-day3
    Administration route: Oral
    Start date: 2012-02-09
    End date: 2012-02-11



Possible Mesna side effects in

Reported by a physician from Norway on 2012-03-07

Patient:

Reactions: Stomatitis, Haematuria, Haemoglobin Abnormal, Pyrexia, Platelet Disorder, Blood Creatinine Abnormal, Transaminases Abnormal, Off Label Use, White Blood Cell Count Abnormal, Hospitalisation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Sarcoma

Mesna

Ifosfamide
    Indication: Sarcoma

Ifosfamide

Mesna
    Indication: Sarcoma

Doxorubicin HCL

Ifosfamide

Radiation Therapy NOS
    Indication: Sarcoma

Doxorubicin HCL

Mesna



Possible Mesna side effects in

Reported by a physician from Norway on 2012-03-01

Patient:

Reactions: Stomatitis, Haemoglobin Abnormal, Haematuria, Pyrexia, Platelet Disorder, Blood Creatinine Abnormal, Transaminases Abnormal, Off Label Use, Hospitalisation, White Blood Cell Count Abnormal

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Doxorubicin HCL

Ifosfamide

Mesna
    Indication: Sarcoma

Ifosfamide

Radiation Therapy NOS
    Indication: Sarcoma

Ifosfamide
    Indication: Sarcoma

Doxorubicin HCL
    Indication: Sarcoma

Mesna

Doxorubicin HCL

Mesna



Possible Mesna side effects in 11 year old male

Reported by a physician from United States on 2012-02-17

Patient: 11 year old male

Reactions: Pyrexia, Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: 60 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Ifosfamide
    Dosage: 2.8 g/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Dosage: 4 mg/kg, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna
    Dosage: 360 mg/m2, unk

Etoposide
    Dosage: unk
    Indication: Sarcoma
    Start date: 2001-10-02

Methotrexate
    Dosage: 12 g/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Filgrastim
    Dosage: 5 mug/kg, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Leucovorin Calcium
    Dosage: 15 mg, unk
    Administration route: Oral
    Indication: Sarcoma
    Start date: 2001-10-02

Doxorubicin HCL
    Dosage: 37.5 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Dexrazoxane Hydrochloride
    Dosage: 375 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna
    Dosage: 560 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Dosage: 2 mg/kg, unk



Possible Mesna side effects in female

Reported by a physician from United States on 2012-01-23

Patient: female, weighing 16.0 kg (35.2 pounds)

Reactions: Respiratory Disorder, Hyperkalaemia, Coagulopathy, Tachycardia, Pyrexia, Pericardial Effusion, Liver Disorder, Cardiac Disorder, Stem Cell Transplant, Multi-Organ Failure, Electrolyte Imbalance, Fluid Retention, Lethargy, Anuria, Vomiting, Renal Disorder, Metabolic Acidosis, Hyperphosphataemia, Nausea, Hypotension, General Physical Health Deterioration, Skin Oedema, Hypercalcaemia, Ascites, Lung Disorder, Pseudomonas Test Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mesna
    Dosage: 670 mg

Cisplatin
    Dosage: 153 mg

Vincristine Sulfate
    Dosage: 1.53 mg

Topotecan
    Dosage: 6 mg

Carboplatin
    Dosage: 880 mg

Etoposide
    Dosage: 1172 mg

Cyclophosphamide
    Dosage: 4760 mg

Doxorubicin HCL
    Dosage: 60 mg

Melphalan Hydrochloride
    Dosage: 111 mg



Possible Mesna side effects in 21 year old male

Reported by a consumer/non-health professional from France on 2012-01-13

Patient: 21 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Rash Morbilliform, Pyrexia, Transaminases Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Etopophos Preservative Free
    Dosage: from d1 to d3,course 1,course 2 on 12dec11,14dec11;d2
    Indication: Hodgkin's Disease
    Start date: 2011-11-22

Zofran
    Dosage: 1 df : 1 intake,14dec11;d2
    Administration route: Oral
    Start date: 2011-11-22

Bactrim DS
    Dosage: 1 df : 1 tab

Doxorubicin HCL
    Dosage: d1
    Indication: Hodgkin's Disease

Bleomycin Sulfate
    Dosage: on d8
    Indication: Hodgkin's Disease

Matulane
    Dosage: from d1 to d7,14dec11;d2,received until 06-dec-2011 instead of 28-nov-2011,
    Administration route: Oral
    Indication: Hodgkin's Disease
    Start date: 2011-11-22
    End date: 2011-12-06

Vincristine
    Dosage: on d8
    Indication: Hodgkin's Disease

Prednisone TAB
    Dosage: from d1 to d10
    Indication: Premedication

Emend

Valacyclovir Hydrochloride

Cyclophosphamide
    Dosage: d1
    Indication: Hodgkin's Disease

Mesna
    Dosage: d1



Possible Mesna side effects in male

Reported by a physician from United States on 2011-12-23

Patient: male

Reactions: Vomiting, Pain, Tachycardia, Rhinorrhoea, Pyrexia, Irritability, Candida Test Positive, Neutropenic Infection, Escherichia Test Positive, Diarrhoea, Feeling Hot, Tachypnoea, Septic Shock, Cough, Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ifosfamide
    Indication: Sarcoma
    Start date: 2001-10-02

Cisplatin
    Indication: Sarcoma
    Start date: 2001-10-02

Methotrexate
    Indication: Sarcoma
    Start date: 2001-10-02

Doxorubicin HCL
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Dosage: over 90 minutes on day 1, every week for 37 weeks
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna

Filgrastim
    Dosage: then over 15 minutes at hours 8,11,14 post infosamide at 1.8 g/m2 over 4 hours daily for 5 days
    Indication: Sarcoma
    Start date: 2001-10-02

Leucovorin Calcium
    Administration route: Oral
    Indication: Sarcoma
    Start date: 2001-10-02

Etoposide
    Dosage: then over 15 minutes at hours 8,11,14 post infosamide at 1.8 g/m2 over 4 hours daily for 5 days
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Dosage: on day 1(loading dose)
    Start date: 2001-10-02

Dexrazoxane Hydrochloride
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna
    Dosage: then over 15 minutes at hours 8,11,14 post infosamide at 1.8 g/m2 over 4 hours daily for 5 days
    Indication: Sarcoma
    Start date: 2001-10-02



Possible Mesna side effects in 11 year old male

Reported by a consumer/non-health professional from United States on 2011-12-22

Patient: 11 year old male

Reactions: Pyrexia, Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna
    Indication: Sarcoma
    Start date: 2001-10-02

Doxorubicin HCL
    Indication: Sarcoma
    Start date: 2001-10-02

Leucovorin Calcium
    Administration route: Oral
    Indication: Sarcoma
    Start date: 2001-10-02

Ifosfamide
    Indication: Sarcoma
    Start date: 2001-10-02

Etoposide
    Indication: Sarcoma
    Start date: 2001-10-02

Filgrastim
    Indication: Sarcoma
    Start date: 2011-10-02

Dexrazoxane Hydrochloride
    Indication: Sarcoma
    Start date: 2001-10-02

Methotrexate
    Indication: Sarcoma
    Start date: 2001-10-02



Possible Mesna side effects in 11 year old male

Reported by a physician from United States on 2011-11-29

Patient: 11 year old male

Reactions: Pyrexia, Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Ifosfamide
    Dosage: 2.8 g/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna
    Dosage: 560 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Filgrastim
    Dosage: 5 mug/kg, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Cisplatin
    Dosage: 60 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Dexrazoxane Hydrochloride
    Dosage: 375 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Mesna
    Dosage: 360 mg/m2, unk

Etoposide
    Dosage: unk
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Dosage: 4 mg/kg, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Doxorubicin HCL
    Dosage: 37.5 mg/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02

Leucovorin Calcium
    Dosage: 15 mg, unk
    Administration route: Oral
    Indication: Sarcoma
    Start date: 2001-10-02

Trastuzumab
    Dosage: 2 mg/kg, unk

Methotrexate
    Dosage: 12 g/m2, unk
    Indication: Sarcoma
    Start date: 2001-10-02



Possible Mesna side effects in male

Reported by a physician from United States on 2011-10-26

Patient: male, weighing 65.8 kg (144.8 pounds)

Reactions: White Blood Cell Count Decreased, Pneumonia, Vomiting, Nausea, Hypotension, Pyrexia, Headache, Hypokalaemia, Fatigue

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ifosfamide
    Dosage: 24.775 g

Mesna
    Dosage: 24.75 g

Etoposide
    Dosage: 875 mg



Possible Mesna side effects in 11 year old male

Reported by a individual with unspecified qualification from United States on 2011-10-26

Patient: 11 year old male

Reactions: Hypersensitivity, Angioedema, Hypotension, Disseminated Intravascular Coagulation, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Eosinophilia, Respiratory Failure, Oliguria, Hypoxia, Leukocytosis, Rash Maculo-Papular, Septic Shock, Leukopenia, Renal Failure Acute

Drug(s) suspected as cause:
Mesna
    Dosage: 500 mg/m2, intravenous (not otherwise specified) 1500 mg/m2, intravenous (not otherwise specified)
    Indication: Primitive Neuroectodermal Tumour

Amifostine
    Dosage: 600 mg/m2
    Indication: Primitive Neuroectodermal Tumour

Other drugs received by patient: Cisplatin; Cyclophosphamide; Vincristine

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017