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Mercaptopurine (Mercaptopurine) - Pyrexia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Pyrexia (32)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Mercaptopurine where reactions include pyrexia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 32   Next >>

Possible Mercaptopurine side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-21

Patient: male, weighing 63.5 kg (139.7 pounds)

Reactions: Night Sweats, Cellulitis, Hepatosplenic T-Cell Lymphoma, Pyrexia, Thirst, Laryngitis, Leukocytoclastic Vasculitis, Epstein-Barr Virus Infection, Fatigue, Sinus Headache, Bacterial Infection, Vision Blurred, Pharyngitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Start date: 2000-06-16

Remicade
    Start date: 2000-02-03

Remicade
    Start date: 2003-01-06

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Indication: Crohn's Disease
    Start date: 1999-11-01
    End date: 2001-02-01

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1998-05-01

Remicade
    Start date: 2002-11-15

Remicade
    Start date: 2002-09-27

Remicade
    Start date: 1999-12-03

Remicade
    Start date: 1999-09-01

Remicade
    Start date: 2002-06-21

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-12-01

Remicade
    Indication: Crohn's Disease
    Start date: 2000-08-17

Remicade
    Start date: 2000-11-05

Remicade
    Start date: 2002-08-09

Remicade
    Start date: 2002-02-22

Remicade
    Start date: 2002-02-11

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-07-01

Other drugs received by patient: Prilosec; Azathioprine Sodium; Imuran; Prednisone TAB; Corticosteroids; Fosamax



Possible Mercaptopurine side effects in male

Reported by a physician from United Kingdom on 2012-08-21

Patient: male

Reactions: Pelvic Pain, Pyrexia, Anal Fistula, C-Reactive Protein Increased, Splenomegaly, Rectal Abscess, Lethargy, Hepatosplenic T-Cell Lymphoma, Crohn's Disease, Sepsis, Platelet Count Decreased, Diabetic Ketoacidosis, Neutropenia, Rectal Discharge, Leukopenia, Influenza Like Illness

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Indication: Crohn's Disease

Azathioprine Sodium
    Dosage: 2.5 mg/kg
    Indication: Crohn's Disease

Azathioprine Sodium
    Start date: 2002-01-01
    End date: 2006-09-01

Prednisolone
    Indication: Product Used FOR Unknown Indication

Remicade
    Indication: Crohn's Disease
    End date: 2005-09-29

Azathioprine Sodium
    Start date: 2001-06-01

Remicade
    Dosage: stopped in february - march (3rd infusion)
    End date: 2006-02-01

Other drugs received by patient: Metronidazole; Vitamin B-12



Possible Mercaptopurine side effects in male

Reported by a individual with unspecified qualification from United States on 2012-07-23

Patient: male, weighing 54.0 kg (118.8 pounds)

Reactions: White Blood Cell Count Decreased, Pneumonia, Chills, Anaemia, Febrile Neutropenia, Pyrexia, Oropharyngeal Pain, Fatigue, Respiratory Failure, Tachypnoea, Cough, Oxygen Saturation Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 135 mg

Methotrexate
    Dosage: 270 mg

Mercaptopurine
    Dosage: 8000 mg



Possible Mercaptopurine side effects in 17 year old female

Reported by a physician from United States on 2012-06-08

Patient: 17 year old female, weighing 47.6 kg (104.7 pounds)

Reactions: Blood Bilirubin Increased, Pyrexia, Caecitis, Loss of Consciousness, Oedema Peripheral, Pulmonary Oedema, Hypocalcaemia, Acute Respiratory Distress Syndrome, Melaena, Hypertriglyceridaemia, Epistaxis, Dysphagia, Anaemia, Hyperglycaemia, General Physical Health Deterioration, Eating Disorder, Tremor, Cerebral Infarction, Depressed Level of Consciousness, Neutropenia, Confusional State, Dyskinesia, Somnolence, Splenic Infarction, Hypokalaemia, Pleural Effusion, White Blood Cell Count Decreased, Cerebrovascular Accident, Ascites, Diarrhoea, Hypophagia, Hypoalbuminaemia, Sinus Tachycardia, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 60mgm2 cyclic
    Administration route: Oral
    Indication: T-Cell Type Acute Leukaemia

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Cyclophosphamide
    Dosage: 1000mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Methotrexate
    Indication: T-Cell Type Acute Leukaemia

Oncaspar
    Indication: T-Cell Type Acute Leukaemia

Nelarabine
    Dosage: 650mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia
    Start date: 2012-04-13

Cytarabine
    Dosage: 75mgm2 cyclic
    Indication: T-Cell Type Acute Leukaemia

Dalteparin Sodium
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Nystatin; Lansoprazole; Insulin Aspart; Piperacillin and Tazobactam; Vancomycin; Voriconazole



Possible Mercaptopurine side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-25

Patient: female, weighing 14.9 kg (32.8 pounds)

Reactions: Anaemia, Hyponatraemia, Rash, Pyrexia, Ascites, Abdominal Pain Upper, Abdominal Compartment Syndrome, Respiratory Failure, Pneumonia Herpes Viral, Bone Marrow Failure, Neutropenia, Thrombocytopenia, Cardiac Arrest, Septic Shock, Infection in AN Immunocompromised Host

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: .99 mg

Methotrexate
    Dosage: 24.5 mg

Dexamethasone
    Dosage: 17.5 ml

Mercaptopurine
    Dosage: 460 mg



Possible Mercaptopurine side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-25

Patient: female, weighing 14.9 kg (32.8 pounds)

Reactions: Coagulopathy, Hepatic Failure, Pyrexia, Abdominal Pain Upper, Laboratory Test Abnormal, Malaise, Bone Marrow Failure, Thrombocytopenia, Anaemia, Condition Aggravated, Hyponatraemia, Rash, Varicella, Abdominal Compartment Syndrome, Ascites, Respiratory Failure, Pneumonia Herpes Viral, Neutropenia, Immune System Disorder, Cardiac Arrest, Septic Shock

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Dosage: 460 mg

Dexamethasone
    Dosage: 17.5 mg

Vincristine Sulfate
    Dosage: .99 mg

Methotrexate
    Dosage: 24.5 mg



Possible Mercaptopurine side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-11

Patient: female, weighing 14.9 kg (32.8 pounds)

Reactions: Coagulopathy, Hepatic Failure, Pyrexia, Malaise, Bone Marrow Failure, Condition Aggravated, Hyponatraemia, Respiratory Distress, Abdominal Compartment Syndrome, Ascites, Respiratory Failure, Pneumonia Herpes Viral, Neutropenia, Lung Infiltration, Septic Shock, Cardiac Arrest

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine Sulfate
    Dosage: .99 mg

Methotrexate
    Dosage: 24.5 mg

Dexamethasone
    Dosage: 17.5 ml

Mercaptopurine
    Dosage: 460 mg



Possible Mercaptopurine side effects in female

Reported by a physician from United States on 2012-04-26

Patient: female

Reactions: Gastrointestinal Bacterial Infection, Back Pain, Pain in Extremity, Pain of Skin, Injection Site Pain, Pyrexia, Hypoaesthesia, Paraesthesia, Diarrhoea, Bacterial Infection, Abdominal Distension, Pancreatitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Mercaptopurine
    Indication: Product Used FOR Unknown Indication

Humira
    Indication: Crohn's Disease



Possible Mercaptopurine side effects in female

Reported by a physician from United States on 2012-04-25

Patient: female

Reactions: Abdominal Pain, Hyperbilirubinaemia, Dyspnoea, Maternal Exposure During Pregnancy, Pyrexia, Abortion Spontaneous, Hyperhidrosis, Fibromyalgia, Arthralgia, Chest Pain, Pollakiuria, Dizziness, Demyelination

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Remicade
    Dosage: four doses received
    Indication: Crohn's Disease
    Start date: 1999-08-25

Remicade
    Start date: 2002-08-07

Mercaptopurine
    Indication: Crohn's Disease

Remicade
    Start date: 2003-06-12
    End date: 2003-01-01

Remicade
    Start date: 2002-10-04



Possible Mercaptopurine side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-24

Patient: female, weighing 90.8 kg (199.8 pounds)

Reactions: Gastrointestinal Bacterial Infection, Back Pain, Pancreas Infection, Pain in Extremity, Injection Site Pain, Hypoaesthesia, Pyrexia, Paraesthesia, Diarrhoea, Sensory Disturbance, Pancreatitis, Abdominal Distension, Tenderness, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Humira
    Start date: 2010-03-01

Humira
    Indication: Crohn's Disease
    Start date: 2009-01-01
    End date: 2010-01-01

Mercaptopurine
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Slow FE; Levothyroxine Sodium; Zyrtec; Multi-Vitamin; Prilosec



Possible Mercaptopurine side effects in female

Reported by a consumer/non-health professional from Netherlands on 2012-04-20

Patient: female, weighing 58.8 kg (129.4 pounds)

Reactions: Post Transplant Lymphoproliferative Disorder, Pyrexia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 15 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-08
    End date: 2010-06-08

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Methotrexate
    Dosage: 15 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Methotrexate
    Dosage: 15 mg, qd (days 1, 8 and 15)
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-11-20

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Prednisone TAB
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-05-17

Prednisone TAB
    Dosage: 35 mg, qd
    Administration route: Oral
    Start date: 2010-05-18
    End date: 2010-06-14

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-02-03
    End date: 2011-03-02

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2010-12-09
    End date: 2010-12-09

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-03-03
    End date: 2011-03-03

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-09-15
    End date: 2011-09-15

Cytarabine
    Dosage: 310 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-20
    End date: 2010-06-20

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-11-18
    End date: 2010-11-18

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Mercaptopurine
    Dosage: 90 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

PEG-Asparaginase
    Dosage: 1575 iu, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-09-25
    End date: 2010-09-25

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-08-18
    End date: 2010-08-18

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-08-19
    End date: 2010-08-19

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-02-03
    End date: 2011-02-03

Methotrexate
    Dosage: 775 mg, qd
    Start date: 2010-06-23
    End date: 2010-06-23

Mercaptopurine
    Dosage: 75 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Etoposide
    Dosage: 188 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-20
    End date: 2010-06-20

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Vincristine
    Dosage: 1 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-18
    End date: 2010-05-18

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-05-25
    End date: 2010-05-25

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2010-11-11
    End date: 2010-11-11

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-07-21
    End date: 2011-07-21

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-08-18
    End date: 2011-08-18

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-07-23
    End date: 2010-07-23

Cytarabine
    Dosage: 3140 mg, qd
    Start date: 2010-09-23
    End date: 2010-09-24

Evoltra
    Dosage: 33 mg, qdx5
    Start date: 2010-07-20
    End date: 2010-07-24

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Mercaptopurine
    Dosage: 100 mg, qd (days 1-28)
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-11-20

Mercaptopurine
    Dosage: 50 mg, once
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-12

Dexamethasone
    Dosage: 4 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-08
    End date: 2010-06-08

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-03-31
    End date: 2011-03-31

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-04-28
    End date: 2011-04-28

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-05-26
    End date: 2011-05-26

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-06-23
    End date: 2011-06-23

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-12-09
    End date: 2010-12-09

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2011-02-03
    End date: 2011-02-03

Methotrexate
    Dosage: 20 mg, qd (days 1, 8 and 15)
    Administration route: Oral
    Start date: 2011-11-21

Methotrexate
    Dosage: 15 mg, once
    Administration route: Oral
    Start date: 2012-01-12
    End date: 2012-01-12

Mercaptopurine
    Dosage: 100 mg, qd, days 0-27
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-11-11
    End date: 2010-12-08

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-07-30
    End date: 2010-07-30

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2011-02-03
    End date: 2011-02-03

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Methotrexate
    Dosage: 25 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2010-11-11
    End date: 2010-12-08

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Mercaptopurine
    Dosage: 100 mg, qd (days 1-28)
    Administration route: Oral
    Start date: 2011-11-21

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-07-23
    End date: 2010-07-23

Doxorubicin HCL
    Dosage: 66 mg, qd
    Start date: 2010-06-01
    End date: 2010-06-01

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Evoltra
    Dosage: 33 mg, qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-05-15

Methotrexate
    Dosage: 775 mg, qd
    Start date: 2010-06-30
    End date: 2010-06-30

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-02-03
    End date: 2011-03-02

Etoposide
    Dosage: 188 mg, qd
    Start date: 2010-06-27
    End date: 2010-06-27

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-11-18
    End date: 2010-11-18

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-12-09
    End date: 2010-12-09

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-06-01
    End date: 2010-06-01

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-01-06
    End date: 2011-01-06

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-07-30
    End date: 2010-07-30

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

PEG-Asparaginase
    Dosage: 1575 iu, qd
    Start date: 2010-10-10
    End date: 2010-10-10

Doxorubicin HCL
    Dosage: 66 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-25
    End date: 2010-05-25

Prednisone TAB
    Dosage: 60 mg, qd
    Administration route: Oral
    Start date: 2010-08-19
    End date: 2010-09-16

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2010-11-11
    End date: 2010-12-08

Cytarabine
    Dosage: 310 mg, qd
    Start date: 2010-06-27
    End date: 2010-06-27



Possible Mercaptopurine side effects in 76 year old male

Reported by a consumer/non-health professional from United States on 2012-04-16

Patient: 76 year old male, weighing 79.4 kg (174.6 pounds)

Reactions: Renal Failure, Activities of Daily Living Impaired, Pyrexia, Headache, Asthenia

Adverse event resulted in: life threatening event, disablity

Drug(s) suspected as cause:
Mercaptopurine



Possible Mercaptopurine side effects in female

Reported by a physician from Netherlands on 2012-03-16

Patient: female, weighing 58.8 kg (129.4 pounds)

Reactions: Post Transplant Lymphoproliferative Disorder, Pyrexia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 15 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-08
    End date: 2010-06-08

Methotrexate
    Dosage: 775 mg, qd
    Start date: 2010-06-30
    End date: 2010-06-30

Methotrexate
    Dosage: 15 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-07-30
    End date: 2010-07-30

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-05-25
    End date: 2010-05-25

Cytarabine
    Dosage: 310 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-20
    End date: 2010-06-20

Evoltra
    Dosage: 33 mg, qdx5
    Start date: 2010-07-20
    End date: 2010-07-24

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-02-03
    End date: 2011-03-02

Mercaptopurine
    Dosage: 100 mg, qd (days 1-28)
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-11-20

Doxorubicin HCL
    Dosage: 66 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-25
    End date: 2010-05-25

Prednisone TAB
    Dosage: 60 mg, qd
    Administration route: Oral
    Start date: 2010-08-19
    End date: 2010-09-16

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Vincristine
    Dosage: 1 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-18
    End date: 2010-05-18

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-01-06
    End date: 2011-01-06

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-04-28
    End date: 2011-04-28

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Mercaptopurine
    Dosage: 100 mg, qd, days 0-27
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-11-11
    End date: 2010-12-08

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Mercaptopurine
    Dosage: 100 mg, qd (days 1-28)
    Administration route: Oral
    Start date: 2011-11-21
    End date: 2012-01-12

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-07-23
    End date: 2010-07-23

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-05-26
    End date: 2011-05-26

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-07-30
    End date: 2010-07-30

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-11-18
    End date: 2010-11-18

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Mercaptopurine
    Dosage: 75 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2010-11-11
    End date: 2010-12-08

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-08-19
    End date: 2010-08-19

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2010-12-09
    End date: 2010-12-09

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-07-21
    End date: 2011-07-21

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-08-18
    End date: 2011-08-18

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-07-23
    End date: 2010-07-23

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-12-09
    End date: 2010-12-09

Methotrexate
    Dosage: 25 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2010-11-11
    End date: 2010-12-08

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Methotrexate
    Dosage: 15 mg, qd (days 1, 8 and 15)
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-11-20

Etoposide
    Dosage: 188 mg, qd
    Start date: 2010-06-27
    End date: 2010-06-27

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

PEG-Asparaginase
    Dosage: 1575 iu, qd
    Start date: 2010-10-10
    End date: 2010-10-10

Doxorubicin HCL
    Dosage: 66 mg, qd
    Start date: 2010-06-01
    End date: 2010-06-01

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-08-18
    End date: 2010-08-18

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-06-01
    End date: 2010-06-01

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-02-03
    End date: 2011-02-03

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-03-31
    End date: 2011-03-31

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-06-23
    End date: 2011-06-23

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-09-15
    End date: 2011-09-15

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Evoltra
    Dosage: 33 mg, qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-05-15

Methotrexate
    Dosage: 775 mg, qd
    Start date: 2010-06-23
    End date: 2010-06-23

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Methotrexate
    Dosage: 20 mg, qd (days 1, 8 and 15)
    Administration route: Oral
    Start date: 2011-11-21
    End date: 2012-01-12

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Etoposide
    Dosage: 188 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-20
    End date: 2010-06-20

Dexamethasone
    Dosage: 4 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-08
    End date: 2010-06-08

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-11-18
    End date: 2010-11-18

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2011-02-03
    End date: 2011-02-03

PEG-Asparaginase
    Dosage: 1575 iu, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-09-25
    End date: 2010-09-25

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-02-03
    End date: 2011-03-02

Cytarabine
    Dosage: 3140 mg, qd
    Start date: 2010-09-23
    End date: 2010-09-24

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2011-02-03
    End date: 2011-02-03

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Mercaptopurine
    Dosage: 90 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-12-09
    End date: 2010-12-09

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Prednisone TAB
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-05-17

Prednisone TAB
    Dosage: 35 mg, qd
    Administration route: Oral
    Start date: 2010-05-18
    End date: 2010-06-14

Prednisone TAB
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2010-11-11
    End date: 2010-11-11

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-03-03
    End date: 2011-03-03

Cytarabine
    Dosage: 310 mg, qd
    Start date: 2010-06-27
    End date: 2010-06-27



Possible Mercaptopurine side effects in female

Reported by a consumer/non-health professional from Netherlands on 2012-03-09

Patient: female, weighing 58.8 kg (129.4 pounds)

Reactions: Post Transplant Lymphoproliferative Disorder, Pyrexia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 25 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2010-11-11
    End date: 2010-12-08

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-08-18
    End date: 2010-08-18

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-02-03
    End date: 2011-03-02

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-05-26
    End date: 2011-05-26

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-09-15
    End date: 2011-09-15

Cytarabine
    Dosage: 310 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-20
    End date: 2010-06-20

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2011-02-03
    End date: 2011-02-03

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-05-25
    End date: 2010-05-25

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-03-31
    End date: 2011-03-31

Cytarabine
    Dosage: 310 mg, qd
    Start date: 2010-06-27
    End date: 2010-06-27

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Methotrexate
    Dosage: 775 mg, qd
    Start date: 2010-06-30
    End date: 2010-06-30

Methotrexate
    Dosage: 15 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-12-09
    End date: 2010-12-09

Prednisone
    Dosage: 60 mg, qd
    Administration route: Oral
    Start date: 2010-08-19
    End date: 2010-09-16

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-08-18
    End date: 2011-09-14

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2010-11-11
    End date: 2010-11-11

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-03-03
    End date: 2011-03-03

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-08-18
    End date: 2011-08-18

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-07-30
    End date: 2010-07-30

Methotrexate
    Dosage: 15 mg, qd once a week
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-11-20

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-07-23
    End date: 2010-07-23

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-09-02
    End date: 2010-09-02

Doxorubicin HCL
    Dosage: 66 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-25
    End date: 2010-05-25

Prednisone
    Dosage: 35 mg, qd
    Administration route: Oral
    Start date: 2010-05-18
    End date: 2010-06-14

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-09-15
    End date: 2011-10-13

Vincristine
    Dosage: 1 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-18
    End date: 2010-05-18

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-04-28
    End date: 2011-05-25

Cytarabine
    Dosage: 3140 mg, qd
    Start date: 2010-09-23
    End date: 2010-09-24

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-12-09
    End date: 2010-12-09

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2011-02-03
    End date: 2011-02-03

Evoltra
    Dosage: 33 mg, qdx5
    Start date: 2010-07-20
    End date: 2010-07-24

Methotrexate
    Dosage: 775 mg, qd
    Start date: 2010-06-23
    End date: 2010-06-23

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-03-03
    End date: 2011-03-30

Mercaptopurine
    Dosage: 100 mg, qd
    Administration route: Oral
    Start date: 2011-11-21
    End date: 2012-01-12

Etoposide
    Dosage: 188 mg, qd
    Start date: 2010-06-27
    End date: 2010-06-27

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-11-18
    End date: 2010-11-18

PEG-Asparaginase
    Dosage: 1575 iu, qd
    Start date: 2010-10-10
    End date: 2010-10-10

Prednisone
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-05-17

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2010-12-09
    End date: 2010-12-09

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-01-06
    End date: 2011-01-06

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-02-03
    End date: 2011-02-03

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-04-28
    End date: 2011-04-28

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-06-23
    End date: 2011-06-23

Evoltra
    Dosage: 33 mg, qdx5
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-05-15

Methotrexate
    Dosage: 17.5 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Mercaptopurine
    Dosage: 100 mg, qd, days 0-27
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-11-11
    End date: 2010-12-08

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-03-31
    End date: 2011-04-27

Etoposide
    Dosage: 188 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-20
    End date: 2010-06-20

PEG-Asparaginase
    Dosage: 1575 iu, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-09-25
    End date: 2010-09-25

Doxorubicin HCL
    Dosage: 66 mg, qd
    Start date: 2010-06-01
    End date: 2010-06-01

Doxorubicin HCL
    Dosage: 62 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-06-01
    End date: 2010-06-01

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-07-23
    End date: 2010-07-23

Methotrexate
    Dosage: 15 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-08
    End date: 2010-06-08

Methotrexate
    Dosage: 20 mg, qd on day 7, 14, 21
    Administration route: Oral
    Start date: 2011-07-21
    End date: 2011-08-17

Methotrexate
    Dosage: 20 mg, qd once a week
    Administration route: Oral
    Start date: 2011-11-21
    End date: 2012-01-12

Mercaptopurine
    Dosage: 75 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2010-12-09
    End date: 2011-01-05

Mercaptopurine
    Dosage: 90 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-01-06
    End date: 2011-02-02

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-02-03
    End date: 2011-03-02

Mercaptopurine
    Dosage: 50 mg, qd, days 0-27
    Administration route: Oral
    Start date: 2011-06-23
    End date: 2011-07-20

Mercaptopurine
    Dosage: 100 mg, qd
    Administration route: Oral
    Start date: 2011-10-14
    End date: 2011-11-20

Dexamethasone
    Dosage: 4 mg, qd
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-06-08
    End date: 2010-06-08

Dexamethasone
    Dosage: 4 mg, qd
    Start date: 2010-07-30
    End date: 2010-07-30

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2010-11-11
    End date: 2010-12-08

Prednisone
    Dosage: 55 mg, qd, days 0-6
    Administration route: Oral
    Start date: 2011-05-26
    End date: 2011-06-22

Vincristine
    Dosage: 1 mg, qd
    Start date: 2010-08-19
    End date: 2010-08-19

Vincristine
    Dosage: 2 mg, qd, day 1 of every month
    Start date: 2011-07-21
    End date: 2011-07-21

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-08-26
    End date: 2010-08-26

Cytarabine
    Dosage: 80 mg, qd
    Start date: 2010-11-18
    End date: 2010-11-18



Possible Mercaptopurine side effects in female

Reported by a physician from Switzerland on 2012-02-20

Patient: female

Reactions: Pancytopenia, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Trisenox
    Start date: 2009-01-29

Atracurium Besylate
    Administration route: Oral
    Start date: 2009-06-18
    End date: 2009-07-02

Trisenox
    Start date: 2009-04-08

Methotrexate
    Administration route: Oral
    Start date: 2009-06-18
    End date: 2009-07-09

Mercaptopurine
    Administration route: Oral
    Start date: 2009-06-18
    End date: 2009-07-11

Other drugs received by patient: Amikin; Levofloxacin; Nopil Forte; Cefepime; Cefepime; Nopil Forte; Cefepime; Bactrim DS; Levofloxacin



Possible Mercaptopurine side effects in 63 year old male

Reported by a pharmacist from United States on 2012-02-17

Patient: 63 year old male

Reactions: Myalgia, Night Sweats, Headache, Pyrexia

Drug(s) suspected as cause:
Mercaptopurine



Possible Mercaptopurine side effects in female

Reported by a health professional (non-physician/pharmacist) from Netherlands on 2012-02-14

Patient: female, weighing 58.8 kg (129.4 pounds)

Reactions: Post Transplant Lymphoproliferative Disorder, Pyrexia

Adverse event resulted in: death, hospitalization, disablity

Drug(s) suspected as cause:
Evoltra
    Dosage: 33 mg, unk
    Start date: 2011-07-20
    End date: 2011-07-24

Mercaptopurine
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-12
    End date: 2012-01-12

Methotrexate
    Dosage: 15 mg, qw
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-12
    End date: 2012-01-12

Evoltra
    Dosage: 33 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11



Possible Mercaptopurine side effects in female

Reported by a physician from Netherlands on 2012-02-07

Patient: female, weighing 58.8 kg (129.4 pounds)

Reactions: Post Transplant Lymphoproliferative Disorder, Pyrexia

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Methotrexate
    Dosage: 15 mg, qw
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-12
    End date: 2012-01-12

Mercaptopurine
    Dosage: 50 mg, qd
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-01-12
    End date: 2012-01-12

Evoltra
    Dosage: 33 mg, unk
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2010-05-11
    End date: 2010-07-24



Possible Mercaptopurine side effects in 9 year old female

Reported by a physician from United States on 2012-01-30

Patient: 9 year old female, weighing 39.4 kg (86.7 pounds)

Reactions: Tachycardia, Pulmonary Embolism, Pyrexia, Constipation, Somnolence, Hypokalaemia, Partial Seizures, Sinusitis, Blepharospasm, Atrial Thrombosis, Hypotension, Cerebral Atrophy, Rash, Varicella Virus Test Positive, Tremor, Haemoglobin Decreased, Fungal Infection, Bacteraemia, Lacunar Infarction, Hypoalbuminaemia, Platelet Count Decreased, Neutropenia, Seizure Like Phenomena

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 100 mg, 3x/day, subuctaneous; 100 mg once, subcutaneous
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-07
    End date: 2011-06-10

Cytarabine
    Dosage: 100 mg, 3x/day, subuctaneous; 100 mg once, subcutaneous
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-13
    End date: 2011-06-16

Vincristine Sulfate
    Dosage: 2 mg, weekly, intravenous; 1.9 mg, single, intravenous
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-04-08
    End date: 2011-04-29

Vincristine Sulfate
    Dosage: 2 mg, weekly, intravenous; 1.9 mg, single, intravenous
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-20
    End date: 2011-06-20

*peg-Asparaginase (Asparaginase) Unknown
    Dosage: 3150 iu, single, intramuscular
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-20
    End date: 2011-06-20

Methotrexate
    Dosage: see image
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-06
    End date: 2011-06-06

Methotrexate
    Dosage: see image
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-13
    End date: 2011-06-13

Methotrexate
    Dosage: see image
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-05-06
    End date: 2011-05-06

Methotrexate
    Dosage: see image
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-20
    End date: 2011-06-20

Methotrexate
    Dosage: see image
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-04-15
    End date: 2011-04-15

Dalteparin Sodium
    Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
    Indication: Pulmonary Embolism
    Start date: 2011-05-13
    End date: 2011-06-26

Dalteparin Sodium
    Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
    Indication: Atrial Thrombosis
    Start date: 2011-05-13
    End date: 2011-06-26

Dalteparin Sodium
    Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
    Indication: Pulmonary Embolism
    Start date: 2011-06-27

Dalteparin Sodium
    Dosage: 5395 iu, 2x/day, subcutaneous; 5395 iu, 2x/day, subcutaneous
    Indication: Atrial Thrombosis
    Start date: 2011-06-27

Cyclophosphamide
    Dosage: 1300 mg single, intravenous; 100mg once, subcutaneous
    Start date: 2011-06-06
    End date: 2011-06-06

Mercaptopurine
    Dosage: 75 mg, once daily six days per week, oral; 100 mg, once per day on seventh day of week, oral
    Administration route: Oral
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-06
    End date: 2011-06-19

Mercaptopurine
    Dosage: 75 mg, once daily six days per week, oral; 100 mg, once per day on seventh day of week, oral
    Administration route: Oral
    Indication: B Precursor Type Acute Leukaemia
    Start date: 2011-06-06
    End date: 2011-06-19

Other drugs received by patient: Zofran; Bactrim; Sodium Chloride 0.9%; Heparin; Ranitidine Hydrochloride; Emla; Acetaminophen



Possible Mercaptopurine side effects in female

Reported by a consumer/non-health professional from United States on 2012-01-28

Patient: female

Reactions: Pyrexia

Drug(s) suspected as cause:
Mercaptopurine
    Indication: Product Used FOR Unknown Indication

Humira
    Indication: Product Used FOR Unknown Indication



Possible Mercaptopurine side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-20

Patient: male, weighing 63.5 kg (139.7 pounds)

Reactions: Night Sweats, Cellulitis, Hepatosplenic T-Cell Lymphoma, Pyrexia, Thirst, Laryngitis, Leukocytoclastic Vasculitis, Epstein-Barr Virus Infection, Fatigue, Sinus Headache, Bacterial Infection, Vision Blurred, Pharyngitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Indication: Crohn's Disease
    Start date: 2000-08-17

Remicade
    Start date: 2000-11-05

Remicade
    Start date: 2000-02-03

Remicade
    Start date: 2002-06-21

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Indication: Crohn's Disease
    Start date: 1999-11-01
    End date: 2001-02-01

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-07-01

Remicade
    Start date: 2003-01-06

Remicade
    Start date: 1999-12-03

Remicade
    Start date: 2000-06-16

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-12-01

Remicade
    Start date: 2002-09-27

Remicade
    Start date: 2002-11-15

Remicade
    Start date: 2002-02-11

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1998-05-01

Remicade
    Start date: 1999-09-01

Remicade
    Start date: 2002-02-22

Remicade
    Start date: 2002-08-09

Other drugs received by patient: Prednisone; Imuran; Prilosec; Azathioprine; Fosamax; Corticosteroids



Possible Mercaptopurine side effects in male

Reported by a individual with unspecified qualification from United States on 2011-12-20

Patient: male, weighing 76.4 kg (168.1 pounds)

Reactions: Acute Lymphocytic Leukaemia, Neutropenia, Pyrexia, Leukaemia Recurrent

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Methotrexate
    Dosage: 50 mg

Vincristine Sulfate
    Dosage: 2 mg

Dexamethasone
    Dosage: 50 mg

Mercaptopurine
    Dosage: 1150 mg



Possible Mercaptopurine side effects in 29 year old female

Reported by a physician from United States on 2011-12-09

Patient: 29 year old female

Reactions: Pneumonia Legionella, Dyspnoea, Crohn's Disease, Atrial Fibrillation, Pyrexia, Peripheral Embolism, Fungal Infection, Dehydration, Acute Respiratory Distress Syndrome, Hypertension

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Indication: Crohn's Disease
    Start date: 1999-01-06
    End date: 1999-01-06

Mercaptopurine
    Indication: Product Used FOR Unknown Indication

Prednisone
    Indication: Product Used FOR Unknown Indication
    End date: 1999-01-24

Other drugs received by patient: Hydromorphone HCL; Calcium Channel Blocker; Levofloxacin; Azathioprine; Methadone HCL; Digoxin; Erythromycin; Atenolol; Adenosine; Mesalamine



Possible Mercaptopurine side effects in male

Reported by a physician from United States on 2011-11-18

Patient: male, weighing 47.6 kg (104.7 pounds)

Reactions: Pain, Pyrexia, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: 888 mg

Cyclophosphamide
    Dosage: 1480 mg

Mercaptopurine
    Dosage: 1246 mg

Vincristine Sulfate
    Dosage: 4 mg



Possible Mercaptopurine side effects in male

Reported by a physician from United States on 2011-11-07

Patient: male, weighing 80.5 kg (177.1 pounds)

Reactions: Multi-Organ Failure, Abdominal Pain, Renal Impairment, Dialysis, Liver Function Test Abnormal, Portal Vein Thrombosis, Pleural Effusion, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 52.5 mg

Dexamethasone Sodium Phosphate
    Dosage: 2 mg

Methotrexate
    Dosage: 15 mg

Mercaptopurine
    Dosage: 450 mg



Possible Mercaptopurine side effects in female

Reported by a physician from United States on 2011-11-04

Patient: female

Reactions: Abdominal Pain, Hyperbilirubinaemia, Dyspnoea, Maternal Exposure During Pregnancy, Pyrexia, Hyperhidrosis, Abortion Spontaneous, Arthralgia, Fibromyalgia, Chest Pain, Dizziness, Pollakiuria, Demyelination

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Remicade
    Start date: 2002-08-07

Remicade
    Dosage: four doses received
    Indication: Crohn's Disease
    Start date: 1999-08-25

Remicade
    Start date: 2003-06-12
    End date: 2003-01-01

Remicade
    Start date: 2002-10-04

Mercaptopurine
    Indication: Crohn's Disease



Possible Mercaptopurine side effects in female

Reported by a physician from United States on 2011-10-19

Patient: female

Reactions: Abdominal Pain, Dyspnoea, Hyperbilirubinaemia, Maternal Exposure During Pregnancy, Pyrexia, Abortion Spontaneous, Hyperhidrosis, Fibromyalgia, Arthralgia, Chest Pain, Dizziness, Pollakiuria, Demyelination

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Remicade
    Start date: 2002-08-07

Remicade
    Start date: 2003-06-12
    End date: 2003-01-01

Mercaptopurine
    Indication: Crohn's Disease

Remicade
    Start date: 2002-10-04

Remicade
    Dosage: four doses received
    Indication: Crohn's Disease
    Start date: 1999-08-25



Possible Mercaptopurine side effects in male

Reported by a physician from United Kingdom on 2011-10-14

Patient: male

Reactions: Pyrexia, Pelvic Pain, Anal Fistula, C-Reactive Protein Increased, Splenomegaly, Rectal Abscess, Lethargy, Crohn's Disease, Hepatosplenic T-Cell Lymphoma, Sepsis, Platelet Count Decreased, Neutropenia, Diabetic Ketoacidosis, Rectal Discharge, Leukopenia, Influenza Like Illness

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Azathioprine
    Start date: 2002-01-01
    End date: 2006-09-01

Remicade
    Indication: Crohn's Disease
    End date: 2005-09-29

Prednisolone
    Indication: Ill-Defined Disorder

Mercaptopurine
    Indication: Crohn's Disease

Azathioprine
    Dosage: 2.5 mg/kg
    Indication: Crohn's Disease

Remicade
    Dosage: stopped in february - march (3rd infusion)
    End date: 2006-02-01

Azathioprine
    Start date: 2001-06-01

Other drugs received by patient: Metronidazole; VIT B12



Possible Mercaptopurine side effects in male

Reported by a physician from United States on 2011-10-14

Patient: male, weighing 63.5 kg (139.7 pounds)

Reactions: Night Sweats, Cellulitis, Hepatosplenic T-Cell Lymphoma, Thirst, Pyrexia, Laryngitis, Epstein-Barr Virus Infection, Leukocytoclastic Vasculitis, Fatigue, Sinus Headache, Vision Blurred, Bacterial Infection, Pharyngitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Remicade
    Start date: 2002-11-15

Remicade
    Start date: 2003-01-06

Remicade
    Start date: 2000-02-03

Remicade
    Start date: 2000-06-16

Remicade
    Start date: 1999-09-01

Remicade
    Start date: 1999-12-03

Remicade
    Start date: 2002-02-11

Remicade
    Start date: 2002-08-09

Remicade
    Start date: 2002-02-22

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1998-05-01

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-12-01

Remicade
    Indication: Crohn's Disease
    Start date: 2000-08-17

Remicade
    Start date: 2002-09-27

Remicade
    Start date: 2002-06-21

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Indication: Crohn's Disease
    Start date: 1999-11-01
    End date: 2001-02-01

Remicade
    Start date: 2000-11-05

Mercaptopurine
    Dosage: 25mg am, 25mg pm
    Start date: 1997-07-01

Other drugs received by patient: Fosamax; Prilosec; Prednisone; Steroids; Imuran; Azathioprine



Possible Mercaptopurine side effects in female

Reported by a consumer/non-health professional from United States on 2011-10-14

Patient: female

Reactions: Abdominal Pain, Dyspnoea, Hyperbilirubinaemia, Maternal Exposure During Pregnancy, Pyrexia, Abortion Spontaneous, Hyperhidrosis, Arthralgia, Fibromyalgia, Chest Pain, Dizziness, Pollakiuria, Demyelination

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Remicade
    Start date: 2003-06-12
    End date: 2003-01-01

Remicade
    Start date: 2002-08-07

Remicade
    Dosage: four doses received
    Indication: Crohn's Disease
    Start date: 1999-08-25

Mercaptopurine
    Indication: Crohn's Disease

Remicade
    Start date: 2002-10-04



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