This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Marcaine (Bupivacaine) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (46)
Death (2)
Life Threatening Events (16)
Disability (8)
Reports by Reaction Type
Cardiac Arrest (8),
Anaesthetic Complication (6),
Respiratory Distress (5),
Brain Oedema (4),
Hypoxic-Ischaemic Encephalopathy (4),
Drug Ineffective (3),
Anaphylactic Reaction (3),
Pain (3),
Anaphylactic Shock (3),
Oedema Peripheral (3),
Product Contamination (2),
Anaphylactoid Reaction (2)
Below are a few examples of reports where side effects / adverse reactions may be related to Marcaine (Bupivacaine). For a complete list or a specific selection of reports, please use the links above.
Possible Marcaine side effects in
Reported by a physician from Japan on 2012-08-24
Patient:
Reactions: Cauda Equina Syndrome
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in
Reported by a physician from Japan on 2012-08-24
Patient:
Reactions: Cauda Equina Syndrome
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 22 year old male
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-07-19
Patient: 22 year old male
Reactions: Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Midazolam HCL; Sodium Chloride
Possible Marcaine side effects in 50 year old female
Reported by a physician from Russian Federation on 2012-06-12
Patient: 50 year old female, weighing 80.0 kg (176.0 pounds)
Reactions: Pneumonia, Postresuscitation Encephalopathy, Pulmonary Embolism, Coma, Macular Ischaemia, Cardiomyopathy, Respiratory Distress, Hypoxic-Ischaemic Encephalopathy, Drug-Induced Liver Injury, Brain Oedema, Bronchitis, Cardiac Arrest
Adverse event resulted in: death, life threatening event, disablity
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Dexamethasone; Fragmin; Midazolam; Gamma-Hydroxybutyric Acid; Sodium Oxybate; Perftoran; Hemohes; Ceraxon (Citicoline); Dofamine; Omez; Adrenalin IN OIL INJ; Cytoflavin (Inosine + Nicotinamide + Riboflavin Mononucleotide + Succi
Possible Marcaine side effects in female
Reported by a consumer/non-health professional from United States on 2012-06-05
Patient: female
Reactions: Drug Hypersensitivity
Drug(s) suspected as cause:
Dilaudid
Dosage: unk
Rocephin
Dosage: unk
Marcaine
Dosage: unk
Ibuprofen (Advil)
Dosage: unk
Axil
Dosage: unk
Possible Marcaine side effects in 30 year old female
Reported by a physician from Japan on 2012-05-21
Patient: 30 year old female
Reactions: Hyperaesthesia, Hypoaesthesia, Intentional Drug Misuse
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 68 year old female
Reported by a physician from Japan on 2012-05-03
Patient: 68 year old female
Reactions: Pharyngeal Oedema
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Dosage: dose unknown
Indication: Local Anaesthesia
Marcaine
Dosage: dose unknown
Neurotropin
Dosage: dose unknown
Marcaine
Dosage: dose unknown
Indication: Epidural Anaesthesia
Elcitonin
Dosage: dose unknown
Indication: Local Anaesthesia
Marcaine
Dosage: dose unknown
Neurotropin
Dosage: dose unknown
Indication: Local Anaesthesia
Neurotropin
Dosage: dose unknown
Neurotropin
Dosage: dose unknown
Indication: Epidural Anaesthesia
Marcaine
Dosage: dose unknown
Marcaine
Dosage: dose unknown
Adant
Dosage: dose unknown
Indication: Local Anaesthesia
Possible Marcaine side effects in 28 year old female
Reported by a physician from Russian Federation on 2012-04-30
Patient: 28 year old female
Reactions: Off Label Use, Overdose, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Indication: Spinal Anaesthesia
Methylergobrevin
Diazepam
Possible Marcaine side effects in 68 year old female
Reported by a physician from Japan on 2012-04-25
Patient: 68 year old female
Reactions: Anaphylactic Shock
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Neurotropin
Dosage: dose unknown
Marcaine
Dosage: dose unknown
Adant
Dosage: dose unknown
Indication: Local Anaesthesia
Marcaine
Dosage: dose unknown
Indication: Local Anaesthesia
Marcaine
Dosage: dose unknown
Neurotropin
Dosage: dose unknown
Indication: Local Anaesthesia
Elcitonin
Dosage: dose unknown
Indication: Local Anaesthesia
Possible Marcaine side effects in 56 year old male
Reported by a physician from Norway on 2012-04-04
Patient: 56 year old male
Reactions: Neuropathy Peripheral, Eyelid Disorder
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xylocaine W / Epinephrene
Dosage: 1-3 ml in the skin area to be treated with light
Indication: Local Anaesthesia
Start date: 2008-05-28
End date: 2008-05-28
Marcaine
Start date: 2008-05-28
End date: 2008-05-28
Possible Marcaine side effects in 49 year old male
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-03-26
Patient: 49 year old male
Reactions: Pruritus Generalised, Flushing
Drug(s) suspected as cause:
Gentamicin Sulfate
Dosage: 160 mg milligram(s), intravenous (not otherwise specified)
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-08
End date: 2012-02-09
Ceftriaxone
Dosage: 2 g gram(s), intravenous (not otherwise specified)
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-08
End date: 2012-02-09
Marcaine
Dosage: 13 mg milligram(s), epidural
Indication: Product Used FOR Unknown Indication
Start date: 2012-02-08
End date: 2012-02-08
Possible Marcaine side effects in 56 year old male
Reported by a physician from Norway on 2012-03-20
Patient: 56 year old male
Reactions: Neuropathy Peripheral, Eyelid Disorder
Adverse event resulted in: disablity
Drug(s) suspected as cause:
Xylocaine
Indication: Local Anaesthesia
Start date: 2008-05-28
End date: 2008-05-28
Marcaine
Indication: Local Anaesthesia
Start date: 2008-05-28
End date: 2008-05-28
Possible Marcaine side effects in 48 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-03-19
Patient: 48 year old male, weighing 66.0 kg (145.2 pounds)
Reactions: Anaphylactoid Reaction
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Diazepam; Droperidol
Possible Marcaine side effects in 35 year old female
Reported by a physician from Turkey on 2012-03-13
Patient: 35 year old female, weighing 90.0 kg (198.0 pounds)
Reactions: Anaphylactic Reaction
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Dosage: once
Indication: Spinal Anaesthesia
Ampicillin
Dosage: once
Indication: Endocarditis
Possible Marcaine side effects in female
Reported by a consumer/non-health professional from United States on 2012-03-05
Patient: female, weighing 88.4 kg (194.6 pounds)
Reactions: Pain
Drug(s) suspected as cause:
Flector
Dosage: unk
Indication: Gout
Start date: 2012-02-27
Marcaine
Dosage: unk
Indication: Gout
Start date: 2012-02-27
End date: 2012-02-27
Other drugs received by patient: Fluoxetine; Anastrozole; Bystolic; Multi-Vitamins; Mesalamine; Vitamin B Complex CAP; Losartan
Possible Marcaine side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-01
Patient: 76 year old female, weighing 88.5 kg (194.6 pounds)
Reactions: NO Therapeutic Response, Abasia, Anaphylactic Reaction, Atrial Fibrillation, Unevaluable Event, Feeling Abnormal
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Marcaine
Traumeel
Dosage: 2.2ml, once 014 1 dose
Indication: Contusion
Traumeel
Dosage: 2.2ml, once 014 1 dose
Indication: Pain
Possible Marcaine side effects in 50 year old female
Reported by a physician from Russian Federation on 2012-02-28
Patient: 50 year old female, weighing 80.0 kg (176.0 pounds)
Reactions: Hypoxic-Ischaemic Encephalopathy, Brain Oedema, Respiratory Distress, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Sodium Oxibatum; Dopamine HCL; Epinephrine; Perftoran; Hemohes; Fragmin; Midazolam; Gamma-Hydroxybutyric Acid; Ceraxone; Dexamethasone; Cytoflavine; Omes
Possible Marcaine side effects in 23 year old female
Reported by a physician from Russian Federation on 2012-02-27
Patient: 23 year old female, weighing 96.0 kg (211.2 pounds)
Reactions: Dyspnoea, Renal Disorder, Maternal Exposure During Pregnancy, Adverse Event, Blood Pressure Decreased
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 26 year old female
Reported by a physician from Russian Federation on 2012-02-27
Patient: 26 year old female, weighing 78.0 kg (171.6 pounds)
Reactions: Hypotension, Anaphylactic Shock, Pulmonary Oedema, Bradycardia, Cardiac Arrest, Oxygen Saturation Decreased
Adverse event resulted in: death
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Premedication Drugs (Not Specified); Stabisol GAK; Dimedrole; Pentoxifylline; Saline
Possible Marcaine side effects in 51 year old male
Reported by a physician from Russian Federation on 2012-02-27
Patient: 51 year old male
Reactions: Urticaria, Bronchospasm, Anaphylactic Shock, Rash
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Novocain
Possible Marcaine side effects in
Reported by a physician from Russian Federation on 2012-02-27
Patient:
Reactions: Foetal Hypokinesia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 22 year old female
Reported by a physician from Russian Federation on 2012-02-27
Patient: 22 year old female
Reactions: Vomiting, Nausea, Headache, Nephritis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Ketorolac Tromethamine; Dextrose; Metoclopramide; Reopolyglucine; Rheopolyglukin; Diazepam
Possible Marcaine side effects in 29 year old female
Reported by a physician from Russian Federation on 2012-02-27
Patient: 29 year old female
Reactions: Paresis, Quadriplegia, Respiratory Distress
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Sodium Cefotaxime; Neohemodes; Atropine Sulfate; Acesole; Dithylin; Tractrium; Corglycard; Sodium Chloride; Propofol; Promedole; Drotaverine; Dimedrole; Reamberine; Fentanyl; Penzital; Spasgan; Almagel; Metoclopramide; Ranitidine; Quamatel
Possible Marcaine side effects in female
Reported by a pharmacist from United States on 2012-02-23
Patient: female
Reactions: Anaesthetic Complication
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in female
Reported by a pharmacist from United States on 2012-02-23
Patient: female
Reactions: Anaesthetic Complication, Treatment Failure
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in female
Reported by a pharmacist from United States on 2012-02-23
Patient: female, weighing 147.9 kg (325.3 pounds)
Reactions: Drug Ineffective, Anaesthetic Complication
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 49 year old female
Reported by a physician from United States on 2012-02-22
Patient: 49 year old female
Reactions: Skin Atrophy
Drug(s) suspected as cause:
Kenalog
Start date: 2010-07-07
Marcaine
Start date: 2010-07-07
Possible Marcaine side effects in 44 year old female
Reported by a physician from Russian Federation on 2012-02-21
Patient: 44 year old female, weighing 75.0 kg (165.0 pounds)
Reactions: Apparent Death, Cardiac Arrest
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 70 year old male
Reported by a physician from Romania on 2012-02-16
Patient: 70 year old male, weighing 85.0 kg (187.0 pounds)
Reactions: Drug Effect Decreased, Drug Effect Delayed
Drug(s) suspected as cause:
Marcaine
Possible Marcaine side effects in 48 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-02-15
Patient: 48 year old male, weighing 66.0 kg (145.2 pounds)
Reactions: Anaphylactoid Reaction
Drug(s) suspected as cause:
Marcaine
Other drugs received by patient: Droperidol; Diazepam
|
