Leukine (Sargramostim) - Hospitalization - Suspected Cause - Side Effect Reports

Possible Leukine side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male

Reactions: Rectal Haemorrhage, Constipation, Cardiac Disorder, Hospitalisation, Granulocytopenia, Inappropriate Antidiuretic Hormone Secretion, Thrombocytopenia, Cardiac Failure Congestive, Pneumonia, Anaemia, Pancytopenia, Atrial Fibrillation, Febrile Neutropenia, Syncope, Embolism, Sepsis, Dehydration, Asthenia, Mantle Cell Lymphoma Recurrent, Leukopenia, Deep Vein Thrombosis, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Cyclophosphamide
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Diffuse Large B-Cell Lymphoma

Doxorubicin HCL
    Dosage: on day 1
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Mantle Cell Lymphoma

Leukine
    Dosage: on day 9-15; 250 mcg/m2/day
    Indication: Diffuse Large B-Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Mantle Cell Lymphoma

Prednisone TAB
    Dosage: on days 1-5
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Diffuse Large B-Cell Lymphoma

Rituximab
    Dosage: on day 15; as infusion
    Indication: Mantle Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Diffuse Large B-Cell Lymphoma

Vincristine
    Dosage: on day 1 (maximum dose: 2mg)
    Indication: Mantle Cell Lymphoma

Possible Leukine side effects in 82 year old male

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: 82 year old male, weighing 77.3 kg (170.1 pounds)

Reactions: Haematochezia, Diarrhoea, Arthralgia, Presyncope, Colitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10 mg/kg over 90 min on day 1
    Indication: Malignant Melanoma
    Start date: 2011-04-21
    End date: 2011-06-24

Leukine
    Dosage: 250 mcg, qd, on days 1-14
    Indication: Malignant Melanoma
    Start date: 2011-04-21
    End date: 2011-07-07

Other drugs received by patient: Aspirin; Doxazosin Mesylate; Preservision EYE Vitamin and Mineral Suppl.; Prednisone TAB; Doxazosin Mesylate; Prilosec; Magnesium

Possible Leukine side effects in 82 year old male

Reported by a consumer/non-health professional from United States on 2012-08-10

Patient: 82 year old male

Reactions: Haematochezia, Diarrhoea, Colitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10 mg/kg, qd on day 1of a 21 day cycle
    Indication: Malignant Melanoma
    Start date: 2011-04-21
    End date: 2011-06-24

Leukine
    Dosage: 250 mcg, qd on days1-14 of a 21 day cycle
    Indication: Malignant Melanoma
    Start date: 2011-04-21
    End date: 2011-07-07

Other drugs received by patient: Sulfamethoprim

Possible Leukine side effects in 71 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-27

Patient: 71 year old male, weighing 94.0 kg (206.8 pounds)

Reactions: Abdominal Pain, Syncope, Fatigue, Dyspnoea, Pruritus, Nausea, Adrenal Insufficiency, Cholecystitis, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last dose:20mar12,12jun12.cou:16,10mg/kg over 90 min on day1 ,1q12 weeks(maintenance),917mg
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Leukine
    Dosage: last dose on 07nov2011,courses:16
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Other drugs received by patient: Gentamicin Sulfate; Polymycin B Sulfate; Sodium Chloride; Omeprazole; Zolpidem Tartrate; Diphenhydramine HCL; Famotidine; Lorazepam; Naphazoline HCL; Pheniramine Maleate; Oxycodone HCL; Colace Caps 100 MG; Ondansetron Hydrochloride; Enoxaparin Sodium; Prednisone; Aspirin; Cosyntropin

Possible Leukine side effects in 71 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-26

Patient: 71 year old male, weighing 94.0 kg (206.8 pounds)

Reactions: Abdominal Pain, Fatigue, Syncope, Dyspnoea, Pruritus, Nausea, Adrenal Insufficiency, Cholecystitis, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last dose:20mar12,12jun12.cou:16,10mg/kg over 90 min on day1 ,1q12 weeks(maintenance),917mg
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Leukine
    Dosage: last dose on 07nov2011,courses:16
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Other drugs received by patient: Cosyntropin; Prednisone; Sodium Chloride; Zolpidem Tartrate; Omeprazole; Lorazepam; Naphazoline HCL; Colace Caps 100 MG; Diphenhydramine HCL; Gentamicin Sulfate; Ondansetron Hydrochloride; Oxycodone HCL; Polymycin B Sulfate; Enoxaparin Sodium; Famotidine; Pheniramine Maleate; Aspirin

Possible Leukine side effects in 71 year old male

Reported by a consumer/non-health professional from Germany on 2012-07-26

Patient: 71 year old male, weighing 92.0 kg (202.4 pounds)

Reactions: Blood Pressure Increased, Pruritus, Dyspnoea, Fatigue, Nausea, Rash Maculo-Papular, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10 mg/kg, 90 minutes on day 1, q12 weeks

Ipilimumab
    Dosage: 10 mg/kg, once
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Leukine
    Dosage: 250 mcg, qd (on days 1-14) maintenance therapy

Leukine
    Dosage: 250 mcg, qd (on days 1-14) induction therapy
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Other drugs received by patient: Zolpidem Tartrate; Prednisone; Acetylsalicylic Acid SRT; Lorazepam; Omeprazole; Colace; Lorazepam; Oxycodone HCL

Possible Leukine side effects in

Reported by a consumer/non-health professional from United States on 2012-07-23

Patient:

Reactions: Sick Sinus Syndrome, Hypothyroidism, Conduction Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Antineoplastic Agents
    Dosage: 10 mg/kg, on day 1
    Indication: Malignant Melanoma
    Start date: 2011-04-25
    End date: 2011-06-27

Antineoplastic Agents
    Dosage: 10 mg/kg
    End date: 2011-07-27

Leukine
    Dosage: 250 mcg, qd,
    End date: 2011-08-22

Leukine
    Dosage: 250 mcg, qd
    Indication: Malignant Melanoma
    Start date: 2011-04-25
    End date: 2011-07-31

Possible Leukine side effects in 71 year old male

Reported by a consumer/non-health professional from Germany on 2012-07-23

Patient: 71 year old male, weighing 91.0 kg (200.2 pounds)

Reactions: Abdominal Pain, Angina Unstable, Headache, Transaminases Increased, Fatigue, Malaise, Dizziness, Pulmonary Oedema, Adrenal Insufficiency, Cholecystitis, Enterocolitis, Myocardial Infarction, Sinus Congestion, Cough, Metastatic Malignant Melanoma, Pneumonia, Dyspnoea, Vomiting, Nausea, Alanine Aminotransferase Increased, Hypotension, Rhinorrhoea, Hepatic Steatosis, Anxiety, Lung Disorder, Syncope, Aspartate Aminotransferase Increased, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Antineoplastic Agents
    Dosage: 10 mg/kg, 90 minutes on day 1, q12 weeks

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Start date: 2011-09-13
    End date: 2011-09-13

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Start date: 2011-08-02
    End date: 2011-08-02

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Indication: Malignant Melanoma
    Start date: 2011-10-04
    End date: 2011-10-04

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Start date: 2011-08-23
    End date: 2011-08-23

Leukine
    Dosage: 250 mcg/day, on day 1-14

Leukine
    Dosage: 250 mcg, qd
    Indication: Malignant Melanoma
    Start date: 2011-10-04
    End date: 2011-10-18

Leukine
    Dosage: 250 mcg, qd
    Start date: 2011-09-13
    End date: 2011-09-26

Leukine
    Dosage: 250 mcg, qd
    Start date: 2011-08-02
    End date: 2011-08-15

Leukine
    Dosage: 250 mcg, qd
    Start date: 2011-08-23
    End date: 2011-09-05

Other drugs received by patient: Hydromorphone HCL; Prednisone; Sodium Chloride; Sodium Chloride; Omeprazole; Diphenhydramine HCL; Pepcid; Enoxaparin Sodium; Oxycodone Hydrochloride; Zolpidem Tartrate; Pepcid; Clobetasol Propionate; Oxycodone Hydrochloride; Lorazepam; Famotidine; Polymyxin / Trimethoprim Sulphate; Prednisone; Cosyntropin; Omeprazole; Naphazoline Hydrochloride / Pheniramine Maleate; Ondansetron Hydrochloride; Pepcid; Docusate Sodium; Gentamicin Sulfate; Sodium Chloride

Possible Leukine side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-23

Patient: female, weighing 57.7 kg (127.0 pounds)

Reactions: Abdominal Discomfort, Nausea, Diarrhoea, Injection Site Reaction, Urinary Tract Infection, Colitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: unk
    Start date: 2011-08-04
    End date: 2011-08-25

Ipilimumab
    Dosage: 10 mg/kg, (day 1, q12 wks)
    Indication: Malignant Melanoma
    Start date: 2011-08-04
    End date: 2011-08-04

Ipilimumab
    Dosage: 10 mg/kg, day 1, q12wks
    Start date: 2011-12-29
    End date: 2011-12-29

Ipilimumab
    Dosage: 10 mg/kg, (days 1, q12 wks)
    Start date: 2011-08-25
    End date: 2011-08-25

Leukine
    Dosage: 250 mcg, qd (days 1-14)
    Start date: 2012-01-19
    End date: 2012-02-01

Leukine
    Dosage: 250 mcg, qd(days 1-14)
    Indication: Malignant Melanoma
    Start date: 2011-08-04
    End date: 2011-08-17

Other drugs received by patient: Klonopin; Ascorbic Acid; Wellbutrin; Extra Strength Tylenol; Clonazepam; Effexor; Multi-Vitamins; Lasix; Selenium; Difenhydramin; Aspirin; Vitamin D; Prilosec

Possible Leukine side effects in male

Reported by a physician from Germany on 2012-07-13

Patient: male, weighing 94.8 kg (208.5 pounds)

Reactions: Metastatic Malignant Melanoma, Fatigue, Nausea, Anaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10 mg/kg, q21d
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-16
    End date: 2012-06-06

Leukine
    Dosage: 125 mcg/m2, day 1-14,q21 d
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-16
    End date: 2012-06-19

Other drugs received by patient: Zofran; Senna-Mint WAF; Colace; Omeprazole; MS Contin; Lipitor; Aspirin; Gabapentin; Miralax; Prozac; Ativan

Possible Leukine side effects in 61 year old female

Reported by a consumer/non-health professional from United States on 2012-07-13

Patient: 61 year old female, weighing 59.0 kg (129.8 pounds)

Reactions: Abdominal Pain, Nausea, Diarrhoea, Colitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last dose on 29jun11,no of courses: 6
    Indication: Malignant Melanoma
    Start date: 2011-04-27
    End date: 2011-06-29

Leukine
    Dosage: last dose on 10jul11,no of courses: 6
    Indication: Malignant Melanoma
    Start date: 2011-04-27
    End date: 2011-07-10

Possible Leukine side effects in 71 year old male

Reported by a consumer/non-health professional from United States on 2012-07-10

Patient: 71 year old male, weighing 94.0 kg (206.8 pounds)

Reactions: Abdominal Pain, Dyspnoea, Syncope, Fatigue, Adrenal Insufficiency, Cholecystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last dose:20mar12,12jun12.cou:16,10mg/kg over 90 min on day1 ,1q12 weeks(maintenance),917mg
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Leukine
    Dosage: last dose on 07nov2011,courses:16
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Other drugs received by patient: Cosyntropin; Naphazoline HCL; Prednisone TAB; Polymycin B Sulfate; Sodium Chloride; Diphenhydramine HCL; Docusate Sodium; Gentamicin Sulfate; Lorazepam; Ondansetron HCL; Famotidine; Zolpidem Tartrate; Enoxaparin Sodium; Pheniramine Maleate; Omeprazole; Oxycodone HCL

Possible Leukine side effects in 71 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-07-10

Patient: 71 year old male, weighing 91.0 kg (200.2 pounds)

Reactions: Abdominal Pain, Dyspnoea, Nausea, Alanine Aminotransferase Increased, Hypotension, Transaminases Increased, Hepatic Steatosis, Fatigue, Syncope, Aspartate Aminotransferase Increased, Adrenal Insufficiency, Cholecystitis, Enterocolitis, Sinus Tachycardia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Start date: 2011-09-13
    End date: 2011-09-13

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Start date: 2011-08-23
    End date: 2011-08-23

Antineoplastic Agents
    Dosage: 10 mg/kg, 90 minutes on day 1, q12 weeks

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Start date: 2011-08-02
    End date: 2011-08-02

Antineoplastic Agents
    Dosage: 10 mg/kg, once
    Indication: Malignant Melanoma
    Start date: 2011-10-04
    End date: 2011-10-04

Leukine
    Dosage: 250 mcg, qd
    Start date: 2011-09-13
    End date: 2011-09-26

Leukine
    Dosage: 250 mcg/day, on day 1-14

Leukine
    Dosage: 250 mcg, qd
    Indication: Malignant Melanoma
    Start date: 2011-10-04
    End date: 2011-10-18

Leukine
    Dosage: 250 mcg, qd
    Start date: 2011-08-02
    End date: 2011-08-15

Leukine
    Dosage: 250 mcg, qd
    Start date: 2011-08-23
    End date: 2011-09-05

Other drugs received by patient: Naphazoline Hydrochloride / Pheniramine Maleate; Sodium Chloride; Omeprazole; Diphenhydramine HCL; Docusate Sodium; Polymyxin / Trimethoprim Sulphate; Prednisone; Zolpidem Tartrate; Hydromorphone HCL; Enoxaparin Sodium; Famotidine; Ondansetron Hydrochloride; Cosyntropin; Prednisone; Lorazepam; Clobetasol Propionate; Gentamicin Sulfate; Oxycodone Hydrochloride

Possible Leukine side effects in 80 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-06

Patient: 80 year old male, weighing 89.0 kg (195.8 pounds)

Reactions: Pneumonia, Dehydration, Muscular Weakness, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10mg/kg iv over 90 min on day1.cycle 4 day 1.delayed for 14days.last dose on 08aug11.
    Indication: Malignant Melanoma
    Start date: 2011-06-27

Leukine
    Dosage: last dose:21aug2011
    Indication: Malignant Melanoma
    Start date: 2011-06-27

Possible Leukine side effects in male

Reported by a consumer/non-health professional from Germany on 2012-07-06

Patient: male, weighing 94.8 kg (208.5 pounds)

Reactions: Metastatic Malignant Melanoma, Fatigue, Nausea, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Leukine
    Dosage: 125 mcg/m2, day 1-14,q21 d
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-16
    End date: 2012-06-19

Yervoy
    Dosage: 10 mg/kg, q21d
    Indication: Metastatic Malignant Melanoma
    Start date: 2012-05-16
    End date: 2012-06-06

Other drugs received by patient: Senna-Mint WAF; Colace; Lipitor; Miralax; Zofran; Gabapentin; Omeprazole; Prozac; Ativan; Aspirin; MS Contin

Possible Leukine side effects in 53 year old male

Reported by a physician from United States on 2012-06-29

Patient: 53 year old male

Reactions: Wound Dehiscence, Gastrointestinal Stoma Complication, Wound Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone

Ipilimumab
    Indication: Malignant Melanoma
    Start date: 2011-05-26
    End date: 2012-01-12

Leukine
    Indication: Malignant Melanoma
    Start date: 2011-05-26
    End date: 2012-01-26

Possible Leukine side effects in 71 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-27

Patient: 71 year old male, weighing 111.0 kg (244.2 pounds)

Reactions: Arthralgia, Hypoalbuminaemia, Muscular Weakness, Blood Thyroid Stimulating Hormone Decreased, DRY Skin, Arthritis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10mg/kg over 90 mins on dy 1q12 wk no.of courses:3 total ourses:3 last dose:1apr11 cyc:21dy
    Indication: Malignant Melanoma
    Start date: 2011-02-11

Leukine
    Dosage: cycle:21dys 250mcg/dy sq on dy 1-14 stop dt:14apr11 delay 7 days no.of cou:3 total ourse:3
    Indication: Malignant Melanoma
    Start date: 2011-02-11

Other drugs received by patient: Multi-Vitamins; Acetaminophen; Glucosamine; Celebrex; Oxycodone HCL

Possible Leukine side effects in 49 year old male

Reported by a consumer/non-health professional from United States on 2012-06-25

Patient: 49 year old male, weighing 92.0 kg (202.4 pounds)

Reactions: Abdominal Pain, Pruritus, Diarrhoea, Chills, Hyperhidrosis, Large Intestinal Haemorrhage

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: dose 10 mg/kg, dose last course 921 mg last date administered is 03aug2011
    Indication: Malignant Melanoma
    Start date: 2011-06-13

Leukine
    Dosage: dose: 250 mcg/day (day 1-14) last administered date is 08aug2011
    Indication: Malignant Melanoma
    Start date: 2011-06-13

Possible Leukine side effects in 61 year old male

Reported by a physician from United Kingdom on 2012-06-22

Patient: 61 year old male

Reactions: Vomiting, Pain in Extremity, Aphasia, Muscular Weakness, Pulmonary Embolism, Purpura, Lower Respiratory Tract Infection, Tremor, Fatigue, Diarrhoea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ima950 (Vaccines)
    Dosage: , 4.96 mg;id, , 4.96 mg;id
    Indication: Glioblastoma
    Start date: 2012-02-21
    End date: 2012-02-21

Ima950 (Vaccines)
    Dosage: , 4.96 mg;id, , 4.96 mg;id
    Indication: Glioblastoma
    Start date: 2012-01-03
    End date: 2012-01-03

Leukine
    Dosage: 75 mcg;id, 75 mcg;id
    Indication: Glioblastoma
    Start date: 2012-02-21
    End date: 2012-02-21

Leukine
    Dosage: 75 mcg;id, 75 mcg;id
    Indication: Glioblastoma
    Start date: 2012-01-03
    End date: 2012-01-03

Temozolomide
    Dosage: 200 mg;po 200 mg/m2;po
    Administration route: Oral
    Indication: Glioblastoma
    Start date: 2012-02-28
    End date: 2012-03-03

Other drugs received by patient: Omeprazole; Gliclazide; Clobazam; Levetiracetam; Dexamethasone

Possible Leukine side effects in 61 year old male

Reported by a consumer/non-health professional from United States on 2012-06-15

Patient: 61 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Fatigue, Embolism, Neoplasm Malignant, Hypotension

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: day 1 c3 delayed until 01sep11 start dt:1sep11 last dose:1sep11,4aug11,758mg resumed on 22sep11
    Indication: Malignant Melanoma
    Start date: 2011-07-15
    End date: 2011-10-06

Leukine
    Dosage: c3 delayed until 01sep11 start dt:1sep11 last dose:14sep11(3500mg,17aug11 resumed on 22sep11
    Indication: Malignant Melanoma
    Start date: 2011-07-15
    End date: 2011-10-06

Possible Leukine side effects in 74 year old male

Reported by a consumer/non-health professional from United States on 2012-05-30

Patient: 74 year old male

Reactions: Chills, Alanine Aminotransferase Increased, Pyrexia, Staphylococcal Infection, Liver Function Test Abnormal, Bacterial Sepsis, Lymphocyte Count Decreased, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: daily
    Indication: Malignant Melanoma
    Start date: 2011-05-16
    End date: 2011-05-16

Leukine
    Dosage: daily
    Indication: Malignant Melanoma
    Start date: 2011-05-16
    End date: 2011-05-22

Napcillin Sodium
    Indication: Product Used FOR Unknown Indication

Vicodin
    Indication: Product Used FOR Unknown Indication

Possible Leukine side effects in 61 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-28

Patient: 61 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Fatigue, Neoplasm Malignant, Embolism, Hypotension

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: day 1 c3 delayed until 01sep11 start dt:1sep11 last dose:1sep11 resumed on 22sep11
    Indication: Malignant Melanoma
    Start date: 2011-07-15

Leukine
    Dosage: c3 delayed until 01sep11 start dt:1sep11 last dose:14sep11(3500mcg) resumed on 22sep11
    Indication: Malignant Melanoma
    Start date: 2011-07-15

Possible Leukine side effects in 71 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-28

Patient: 71 year old male, weighing 94.0 kg (206.8 pounds)

Reactions: Syncope, Adrenal Insufficiency, Cholecystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last dose: 20mar2012. courses:14. 10mg/kg over 90 min on day1 ,1q12 weeks(maintenance)
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Leukine
    Dosage: last dose on 07nov2011
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Possible Leukine side effects in 61 year old male

Reported by a consumer/non-health professional from United States on 2012-05-16

Patient: 61 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Fatigue, Embolism, Neoplasm Malignant, Hypotension

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: day 1 c3 delayed until 01sep11 start dt:1sep11 last dose:1sep11 resumed on 22sep11
    Indication: Malignant Melanoma
    Start date: 2011-07-15

Leukine
    Dosage: c3 delayed until 01sep11 start dt:1sep11 last dose:14sep11(3500mcg) resumed on 22sep11
    Indication: Malignant Melanoma
    Start date: 2011-07-15

Possible Leukine side effects in 71 year old male

Reported by a consumer/non-health professional from United States on 2012-05-11

Patient: 71 year old male, weighing 94.0 kg (206.8 pounds)

Reactions: Syncope, Adrenal Insufficiency, Cholecystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last dose on 20mar2012
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Leukine
    Dosage: last dose on 07nov2011
    Indication: Malignant Melanoma
    Start date: 2011-08-02

Possible Leukine side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-16

Patient: 75 year old male, weighing 82.0 kg (180.4 pounds)

Reactions: Hypotension, Dehydration, Hyponatraemia, Atrial Fibrillation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: 10mg/kg iv over 90 mins on d1 q12 wk,no of course-2,last dose on 05jul2011.interrupt on 18jul2011
    Indication: Malignant Melanoma
    Start date: 2011-06-13

Leukine
    Dosage: last admin. 18-jul-2011
    Indication: Malignant Melanoma
    Start date: 2011-06-13

Metoprolol Tartrate

Possible Leukine side effects in 68 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-06

Patient: 68 year old male, weighing 126.0 kg (277.2 pounds)

Reactions: Sepsis, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ipilimumab
    Dosage: last administered date:4oct2011.
    Indication: Malignant Melanoma
    Start date: 2011-08-05

Leukine
    Dosage: last administered date:18oct2011.
    Indication: Malignant Melanoma
    Start date: 2011-08-05

Possible Leukine side effects in 61 year old male

Reported by a physician from United Kingdom on 2012-04-05

Patient: 61 year old male

Reactions: Vomiting, Neutrophil Count Increased, Aphasia, Pulmonary Embolism, Purpura, Tremor, Fatigue, Diarrhoea, Asthenia, White Blood Cell Count Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ima950 (Vaccines)
    Dosage: 4.96 mg;id
    Indication: Glioblastoma
    Start date: 2012-01-03
    End date: 2012-01-03

Ima950 (Vaccines)
    Dosage: 4.96 mg;id
    Indication: Glioblastoma
    Start date: 2012-02-21
    End date: 2012-02-21

Leukine
    Dosage: 75 mcg;id
    Indication: Glioblastoma
    Start date: 2012-01-03
    End date: 2012-01-03

Leukine
    Dosage: 75 mcg;id
    Indication: Glioblastoma
    Start date: 2012-02-21
    End date: 2012-02-21

Temozolomide
    Dosage: 200 mg;po 200 mg/m2;po
    Administration route: Oral
    Indication: Glioblastoma
    Start date: 2012-02-28
    End date: 2012-03-03

Possible Leukine side effects in 53 year old male

Reported by a physician from United States on 2012-03-21

Patient: 53 year old male

Reactions: Wound Dehiscence, Gastrointestinal Stoma Complication, Wound Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone

Ipilimumab
    Indication: Malignant Melanoma
    Start date: 2011-05-26
    End date: 2012-01-12

Leukine
    Indication: Malignant Melanoma
    Start date: 2011-05-26
    End date: 2012-01-26

Possible Leukine side effects in 77 year old male

Reported by a consumer/non-health professional from United States on 2012-03-14

Patient: 77 year old male

Reactions: Vomiting, Nausea, Retching, Hypotension, Bone Pain, Blood Count Abnormal, Throat Tightness, Renal Failure, Dyspepsia, Hiccups, Blood Pressure Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Antineoplastic Agents
    Dosage: unk
    Indication: T-Cell Lymphoma
    Start date: 2012-01-30

Leukine
    Dosage: unk
    Indication: T-Cell Lymphoma
    Start date: 2012-01-31

Leukine
    Dosage: 13 day cycle
    Start date: 2012-02-21