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Lamotrigine (Lamotrigine) - Drug Interaction - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Drug Interaction (59)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Lamotrigine where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 59   Next >>

Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Drug Effect Decreased, Vomiting, Psychomotor Hyperactivity, Orthostatic Hypotension, Abnormal Behaviour, Drug Interaction, Mucosal Dryness, Constipation, Disease Progression, Diplopia, Weight Increased, Dizziness, Oedema

Drug(s) suspected as cause:
Lamotrigine
    Indication: Post-Traumatic Epilepsy

Gabapentin
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Clarithromycin
    Indication: Respiratory Tract Infection

Cabergoline
    Indication: Prolactinoma

Ketoconazole
    Indication: Vulvovaginal Mycotic Infection

Oxcarbazepine
    Dosage: gradually increased to 1200 mg/day

Bromocriptine Mesylate
    Dosage: increased to target dose of 7.5mg daily
    Indication: Prolactinoma

Oxcarbazepine
    Dosage: 600mg
    Indication: Post-Traumatic Epilepsy



Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Vomiting, Drug Effect Decreased, Psychomotor Hyperactivity, Orthostatic Hypotension, Drug Interaction, Abnormal Behaviour, Mucosal Dryness, Constipation, Disease Progression, Diplopia, Weight Increased, Dizziness, Oedema

Drug(s) suspected as cause:
Gabapentin
    Indication: Post-Traumatic Epilepsy

Lamotrigine
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Bromocriptine Mesylate
    Dosage: increased to target dose of 7.5mg daily
    Indication: Prolactinoma

Oxcarbazepine
    Dosage: 600mg
    Indication: Post-Traumatic Epilepsy

Ketoconazole
    Indication: Vulvovaginal Mycotic Infection

Oxcarbazepine
    Dosage: gradually increased to 1200 mg/day

Cabergoline
    Indication: Prolactinoma

Clarithromycin
    Indication: Respiratory Tract Infection



Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Vomiting, Drug Effect Decreased, Psychomotor Hyperactivity, Abnormal Behaviour, Orthostatic Hypotension, Drug Interaction, Mucosal Dryness, Constipation, Disease Progression, Weight Increased, Diplopia, Oedema, Dizziness

Drug(s) suspected as cause:
Lamotrigine
    Indication: Post-Traumatic Epilepsy

Gabapentin
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Cabergoline
    Indication: Prolactinoma

Clarithromycin
    Indication: Respiratory Tract Infection

Bromocriptine Mesylate
    Dosage: increased to target dose of 7.5mg daily
    Indication: Prolactinoma

Oxcarbazepine
    Dosage: 600mg
    Indication: Post-Traumatic Epilepsy

Oxcarbazepine
    Dosage: gradually increased to 1200 mg/day

Ketoconazole
    Indication: Vulvovaginal Mycotic Infection



Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Psychomotor Hyperactivity, Drug Effect Decreased, Vomiting, Abnormal Behaviour, Drug Interaction, Orthostatic Hypotension, Mucosal Dryness, Constipation, Disease Progression, Diplopia, Weight Increased, Oedema, Dizziness

Drug(s) suspected as cause:
Lamotrigine
    Indication: Post-Traumatic Epilepsy

Gabapentin
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Oxcarbazepine
    Dosage: gradually increased to 1200 mg/day

Cabergoline
    Indication: Prolactinoma

Clarithromycin
    Indication: Respiratory Tract Infection

Ketoconazole
    Indication: Vulvovaginal Mycotic Infection

Oxcarbazepine
    Dosage: 600mg
    Indication: Post-Traumatic Epilepsy

Bromocriptine Mesylate
    Dosage: increased to target dose of 7.5mg daily
    Indication: Prolactinoma



Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Psychomotor Hyperactivity, Vomiting, Drug Effect Decreased, Body Mass Index Increased, Drug Interaction, Orthostatic Hypotension, Abnormal Behaviour, Condition Aggravated, Mucosal Dryness, Constipation, Menstrual Disorder, Diplopia, Oedema, Dizziness

Drug(s) suspected as cause:
Clarithromycin
    Indication: Respiratory Tract Infection

Gabapentin
    Indication: Post-Traumatic Epilepsy

Ketoconazole
    Dosage: 7 days
    Indication: Vaginal Lesion

Lamotrigine
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Bromocriptine Mesylate
    Dosage: 7.5 mg/day
    Indication: Prolactinoma

Oxcarbazepine
    Dosage: 1200 mg/day

Oxcarbazepine
    Dosage: 600 mg
    Indication: Post-Traumatic Epilepsy

Bromocriptine Mesylate
    Dosage: 15 mg

Bromocriptine Mesylate
    Dosage: 20 mg

Cabergoline
    Dosage: 0.25 mg, 2/week
    Indication: Prolactinoma

Cabergoline
    Dosage: 2 mg/ week

Other drugs received by patient: Quinagolide



Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Drug Effect Decreased, Vomiting, Psychomotor Hyperactivity, Abnormal Behaviour, Drug Interaction, Orthostatic Hypotension, Mucosal Dryness, Constipation, Disease Progression, Diplopia, Weight Increased, Dizziness, Oedema

Drug(s) suspected as cause:
Gabapentin
    Indication: Post-Traumatic Epilepsy

Lamotrigine
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Bromocriptine Mesylate
    Dosage: increased to target dose of 7.5mg daily
    Indication: Prolactinoma

Cabergoline
    Indication: Prolactinoma

Ketoconazole
    Indication: Vulvovaginal Mycotic Infection

Oxcarbazepine
    Dosage: 600mg
    Indication: Post-Traumatic Epilepsy

Oxcarbazepine
    Dosage: gradually increased to 1200 mg/day

Clarithromycin
    Indication: Respiratory Tract Infection



Possible Lamotrigine side effects in 30 year old female

Reported by a health professional (non-physician/pharmacist) from Poland on 2012-08-23

Patient: 30 year old female

Reactions: Drug Effect Decreased, Vomiting, Psychomotor Hyperactivity, Abnormal Behaviour, Orthostatic Hypotension, Drug Interaction, Mucosal Dryness, Constipation, Disease Progression, Diplopia, Weight Increased, Dizziness, Oedema

Drug(s) suspected as cause:
Lamotrigine
    Indication: Post-Traumatic Epilepsy

Gabapentin
    Indication: Post-Traumatic Epilepsy

Other drugs received by patient possibly interacting with the suspect drug:
Oxcarbazepine
    Dosage: 600mg
    Indication: Post-Traumatic Epilepsy

Bromocriptine Mesylate
    Dosage: increased to target dose of 7.5mg daily
    Indication: Prolactinoma

Ketoconazole
    Indication: Vulvovaginal Mycotic Infection

Oxcarbazepine
    Dosage: gradually increased to 1200 mg/day

Cabergoline
    Indication: Prolactinoma

Clarithromycin
    Indication: Respiratory Tract Infection



Possible Lamotrigine side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-21

Patient: 59 year old female, weighing 83.5 kg (183.7 pounds)

Reactions: C-Reactive Protein Increased, Drug Interaction, Muscular Weakness, Rash Maculo-Papular, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine
    Dosage: 50 mg, bid
    Administration route: Oral
    Indication: Bipolar Disorder

Depakote
    Dosage: 750 mg, tid
    Administration route: Oral
    Indication: Bipolar Disorder

Other drugs received by patient: Quetiapine; Hydroxychloroquine Sulfate; Aspirin; Simvastatin; Venlafaxine



Possible Lamotrigine side effects in 59 year old female

Reported by a physician from United Kingdom on 2012-08-20

Patient: 59 year old female, weighing 83.5 kg (183.7 pounds)

Reactions: Drug Interaction, Muscular Weakness, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine
    Administration route: Oral
    Indication: Bipolar Disorder

Depakote
    Administration route: Oral
    Indication: Bipolar Disorder

Other drugs received by patient: Simvastatin; Quetiapine; Hydroxychloroquine Sulfate; Aspirin; Venlafaxine



Possible Lamotrigine side effects in 59 year old female

Reported by a physician from United Kingdom on 2012-08-20

Patient: 59 year old female, weighing 83.5 kg (183.7 pounds)

Reactions: Drug Interaction, Muscular Weakness, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Depakote
    Administration route: Oral
    Indication: Bipolar Disorder

Lamotrigine
    Administration route: Oral
    Indication: Bipolar Disorder

Other drugs received by patient: Simvastatin; Venlafaxine; Quetiapine; Aspirin; Hydroxychloroquine Sulfate



Possible Lamotrigine side effects in 59 year old female

Reported by a physician from United Kingdom on 2012-08-16

Patient: 59 year old female

Reactions: C-Reactive Protein Increased, Muscular Weakness, Drug Interaction, Rash Maculo-Papular, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine
    Indication: Bipolar Disorder

Depakote
    Indication: Bipolar Disorder

Other drugs received by patient: Simvastatin; Hydroxychloroquine Sulfate; Quetiapine; Aspirin; Venlafaxine



Possible Lamotrigine side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-14

Patient: 44 year old female

Reactions: Drug Eruption, Drug Interaction, Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine
    Dosage: unk
    Indication: Schizophrenia

Clozapine
    Indication: Schizophrenia



Possible Lamotrigine side effects in 59 year old female

Reported by a physician from United Kingdom on 2012-08-10

Patient: 59 year old female, weighing 83.5 kg (183.7 pounds)

Reactions: C-Reactive Protein Increased, Drug Interaction, Muscular Weakness, Rash Maculo-Papular, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Depakote
    Dosage: 2250mg per day
    Administration route: Oral
    Indication: Bipolar Disorder

Lamotrigine
    Dosage: 100mg per day
    Administration route: Oral
    Indication: Bipolar Disorder

Other drugs received by patient: Hydroxychloroquine Sulfate; Venlafaxine; Simvastatin; Quetiapine; Aspirin



Possible Lamotrigine side effects in 59 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-09

Patient: 59 year old female, weighing 83.5 kg (183.7 pounds)

Reactions: Drug Interaction, Stevens-Johnson Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Depakote
    Dosage: 750 mg, 3 in 1 d, oral
    Administration route: Oral
    Indication: Bipolar Disorder

Lamotrigine
    Dosage: 50 mg, 2 in 1 d, oral
    Administration route: Oral
    Indication: Bipolar Disorder

Other drugs received by patient: Venlafaxine HCL; Simvastatin; Quetiapine Fumarate; Hydroxychloroquine Sulfate; Aspirin



Possible Lamotrigine side effects in 45 year old male

Reported by a physician from United States on 2012-08-07

Patient: 45 year old male

Reactions: Dysarthria, Mental Impairment, Drug Interaction, Condition Aggravated, Ataxia, Toxicity To Various Agents, Hallucination, Aggression

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine
    Dosage: 200mg twice per day
    Indication: Epilepsy

Divalproex Sodium
    Dosage: 750mg twice per day
    Indication: Epilepsy

Other drugs received by patient: Topiramate; Vitamin B1 TAB; Vitamin D; Lorazepam; Risperidone



Possible Lamotrigine side effects in 67 year old female

Reported by a physician from Japan on 2012-08-02

Patient: 67 year old female

Reactions: Drug Interaction, Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Risperidone
    Dosage: 5 mg, daily

Risperidone
    Dosage: 3 mg, daily
    Indication: Psychotic Behaviour

Lamotrigine
    Dosage: 25 mg, q 2 days
    Indication: Bipolar Disorder



Possible Lamotrigine side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient: 44 year old female

Reactions: Agranulocytosis, Drug Interaction, Rash, Neuroleptic Malignant Syndrome

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine

Other drugs received by patient possibly interacting with the suspect drug:
Clozapine

Clozapine
    Dosage: dose titrated upward due to persistent psychotic symptoms

Other drugs received by patient: Olanzapine



Possible Lamotrigine side effects in 44 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31

Patient: 44 year old female

Reactions: Agranulocytosis, Drug Interaction, Neuroleptic Malignant Syndrome, Rash

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lamotrigine

Other drugs received by patient possibly interacting with the suspect drug:
Clozapine
    Dosage: dose titrated upward due to persistent psychotic symptoms

Clozapine

Other drugs received by patient: Olanzapine



Possible Lamotrigine side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-17

Patient: female

Reactions: Drug Interaction, Convulsion

Drug(s) suspected as cause:
Calcium
    Indication: Product Used FOR Unknown Indication

Lamotrigine
    Indication: Product Used FOR Unknown Indication



Possible Lamotrigine side effects in 39 year old female

Reported by a consumer/non-health professional from United States on 2012-07-09

Patient: 39 year old female

Reactions: Dystonia, Drug Ineffective, Anticonvulsant Drug Level Decreased, Drug Interaction, Cognitive Disorder, Convulsion, Incoherent, Anticonvulsant Drug Level Increased, Dissociation, Nervous System Disorder, Aura, Drug Level Decreased

Drug(s) suspected as cause:
Lamictal
    Dosage: 550 mg (275 mg, 2 in 1 d), oral
    Administration route: Oral
    Indication: Convulsion
    Start date: 2011-01-01

Lamotrigine
    Dosage: oral
    Administration route: Oral
    Indication: Convulsion

Dilantin
    Dosage: (300 mg)
    Indication: Convulsion

Other drugs received by patient: Tegretol-XR; Clonazepam; Flax Seed (Linum Usitatissimum Seed Oil); Vitamin B Complex (Afi-B-Total / 00322001 / ); Coconut OIL (Cocos Nucifera Oil)



Possible Lamotrigine side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-03

Patient: female

Reactions: Dystonia, Drug Ineffective, Drug Interaction, Anticonvulsant Drug Level Decreased, Cognitive Disorder, Convulsion, Incoherent, Anticonvulsant Drug Level Increased, Dissociation, Nervous System Disorder, Aura

Drug(s) suspected as cause:
Lamotrigine

Other drugs received by patient possibly interacting with the suspect drug:
Dilantin-125
    Dosage: 300 mg
    Indication: Convulsion

Lamictal
    Dosage: 275 mg, 2x/day
    Administration route: Oral
    Indication: Convulsion
    Start date: 2011-01-01

Lamictal
    Dosage: 300 mg, 2x/day
    Administration route: Oral

Other drugs received by patient: Tegretol-XR; Flax Seed; Coconut OIL; Clonazepam; Vitamin B Complex CAP



Possible Lamotrigine side effects in 60 year old female

Reported by a physician from United States on 2012-07-03

Patient: 60 year old female

Reactions: Intention Tremor, Drug Interaction

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Aripiprazole
    Dosage: 5 mg, daily
    Indication: Major Depression
    Start date: 2011-02-01

Lamotrigine
    Dosage: 300 mg, daily for several years
    Indication: Major Depression



Possible Lamotrigine side effects in 43 year old male

Reported by a physician on 2012-06-28

Patient: 43 year old male

Reactions: Back Pain, White Blood Cell Count Decreased, Drug Interaction, Neutropenia

Drug(s) suspected as cause:
Lamotrigine
    Dosage: 200 mg (200 mg,1 in 1 d)
    Indication: Product Used FOR Unknown Indication

Clozapine
    Dosage: (650 mg,1 d),oral ; oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-02

Clozapine
    Dosage: (650 mg,1 d),oral ; oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-07-01
    End date: 2012-04-25

Acetaminophen W / Codeine
    Indication: Back Pain

Ibuprofen
    Indication: Back Pain

Other drugs received by patient: Sulprid (Sulpiride)



Possible Lamotrigine side effects in 39 year old female

Reported by a consumer/non-health professional from United States on 2012-06-20

Patient: 39 year old female

Reactions: Drug Ineffective, Dystonia, Drug Interaction, Convulsion, Incoherent, Dissociation, Anticonvulsant Drug Level Increased, Nervous System Disorder, Memory Impairment, Aura, Drug Level Decreased

Drug(s) suspected as cause:
Lamictal
    Dosage: 275mg twice per day
    Administration route: Oral
    Indication: Convulsion
    Start date: 2011-01-01

Dilantin
    Dosage: 300mg unknown
    Indication: Convulsion

Lamotrigine
    Administration route: Oral
    Indication: Convulsion

Other drugs received by patient: Clonazepam; Vitamin B Complex CAP; Tegretol-XR; Flax Seed; Coconut OIL



Possible Lamotrigine side effects in 43 year old male

Reported by a physician from United Kingdom on 2012-05-31

Patient: 43 year old male

Reactions: Back Pain, Drug Interaction, Neutropenia

Drug(s) suspected as cause:
Ibuprofen
    Dosage: unknown
    Indication: Back Pain

Lamotrigine
    Dosage: 200 mg (200 mg, 1 in 1 d)
    Indication: Product Used FOR Unknown Indication

Clozapine
    Dosage: 650 mg, 1 d, oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-02

Clozapine
    Dosage: 650 mg, 1 d, oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2005-07-01
    End date: 2012-04-25

Acetaminophen W / Codeine
    Dosage: unknown
    Indication: Back Pain

Other drugs received by patient: Sulprid (Sulpride)



Possible Lamotrigine side effects in 18 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-30

Patient: 18 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Drug Interaction, Epilepsy

Drug(s) suspected as cause:
Nexplanon
    Dosage: 68 mg, unknown, implant
    Indication: Contraception
    Start date: 2011-03-01

Keppra
    Indication: Product Used FOR Unknown Indication

Lamotrigine
    Dosage: 200 mg, bid
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2010-11-01

Other drugs received by patient: Doxycycline; Loratadine



Possible Lamotrigine side effects in 18 year old female

Reported by a consumer/non-health professional from United Kingdom on 2012-05-22

Patient: 18 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Drug Interaction, Epilepsy

Drug(s) suspected as cause:
Etonogestrel
    Indication: Contraception
    Start date: 2011-03-01

Keppra
    Indication: Product Used FOR Unknown Indication

Lamotrigine
    Dosage: 400mg per day
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2010-11-01

Other drugs received by patient: Loratadine; Doxycycline



Possible Lamotrigine side effects in 18 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-18

Patient: 18 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Drug Interaction, Epilepsy

Drug(s) suspected as cause:
Lamotrigine

Other drugs received by patient possibly interacting with the suspect drug:
Keppra

Nexplanon
    Dosage: 68 mg, unk
    Indication: Contraception
    Start date: 2011-03-01

Other drugs received by patient: Doxycycline; Loratadine



Possible Lamotrigine side effects in 18 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-11

Patient: 18 year old female, weighing 54.0 kg (118.8 pounds)

Reactions: Drug Interaction, Epilepsy, Convulsion

Drug(s) suspected as cause:
Keppra
    Indication: Product Used FOR Unknown Indication

Nexplanon
    Dosage: 68 mg, unknown, implant
    Indication: Contraception
    Start date: 2011-03-01

Lamotrigine
    Dosage: 200 mg, bid
    Administration route: Oral
    Indication: Epilepsy
    Start date: 2010-11-01

Other drugs received by patient: Loratadine; Doxycycline



Possible Lamotrigine side effects in 42 year old female

Reported by a physician from United States on 2012-05-09

Patient: 42 year old female

Reactions: International Normalised Ratio Increased, Coronary Artery Disease, Drug Interaction, Mitral Valve Incompetence, Left Atrial Dilatation, Adhesion, Epistaxis, Cardiac Failure Congestive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Warfarin Sodium
    Dosage: 2.5 mg

Lamotrigine
    Dosage: 150 mg;qd
    Indication: Bipolar Disorder

Divalproex Sodium
    Dosage: 1000 mg;qd; 250 mg;bid
    Indication: Bipolar Disorder



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