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Isoniazid (Isoniazid) - Liver Disorder - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Liver Disorder (20)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Isoniazid where reactions include liver disorder. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Isoniazid side effects in male

Reported by a physician from Japan on 2012-08-15

Patient: male

Reactions: Liver Disorder

Drug(s) suspected as cause:
Stelara
    Indication: Psoriasis
    Start date: 2012-06-29
    End date: 2012-07-27

Isoniazid
    Indication: Antibiotic Prophylaxis
    Start date: 2012-06-01
    End date: 2012-07-27



Possible Isoniazid side effects in male

Reported by a physician from Japan on 2012-06-11

Patient: male, weighing 58.0 kg (127.6 pounds)

Reactions: Liver Disorder

Drug(s) suspected as cause:
Stelara
    Indication: Psoriasis
    Start date: 2012-05-11

Stelara
    Start date: 2012-03-02

Isoniazid
    Administration route: Oral
    Indication: Prophylaxis
    Start date: 2011-10-14
    End date: 2011-12-15

Isoniazid
    Administration route: Oral

Stelara
    Start date: 2011-10-21

Stelara
    Start date: 2011-11-18

Other drugs received by patient: Ursodiol



Possible Isoniazid side effects in female

Reported by a physician from Japan on 2012-04-09

Patient: female, weighing 55.3 kg (121.7 pounds)

Reactions: Tubulointerstitial Nephritis, Angiotensin Converting Enzyme Increased, Blood Urine Present, Lymphadenopathy, Pulmonary Tuberculosis, Computerised Tomogram Thorax Abnormal, Blood Creatine Increased, Liver Disorder, Sarcoidosis, Blood Creatinine Increased, Lysozyme Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Isoniazid
    Indication: Product Used FOR Unknown Indication

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2010-12-06
    End date: 2011-12-12

Rifampicin
    Indication: Product Used FOR Unknown Indication

Pyrazinamide
    Indication: Product Used FOR Unknown Indication

Ethambutol Hydrochloride
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Amlodipine Besylate; Atorvastatin Calcium; Atorvastatin Calcium; Makyoyokukanto; Keishikajutsubuto; Nitrendipine



Possible Isoniazid side effects in female

Reported by a physician from Japan on 2012-04-05

Patient: female, weighing 55.3 kg (121.7 pounds)

Reactions: Angiotensin Converting Enzyme Increased, Tubulointerstitial Nephritis, Lymphadenopathy, Blood Urine Present, Pulmonary Tuberculosis, Computerised Tomogram Thorax Abnormal, Blood Creatine Increased, Liver Disorder, Interstitial Lung Disease, Sarcoidosis, Blood Creatinine Increased, Lysozyme Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ethambutol Hydrochloride
    Indication: Product Used FOR Unknown Indication

Humira
    Indication: Rheumatoid Arthritis
    Start date: 2010-12-06
    End date: 2011-12-12

Isoniazid
    Indication: Product Used FOR Unknown Indication

Rifampicin
    Indication: Product Used FOR Unknown Indication

Pyrazinamide
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Nitrendipine; Atorvastatin Calcium; Keishikajutsubuto; Amlodipine Besylate; Atorvastatin Calcium; Makyoyokukanto



Possible Isoniazid side effects in 54 year old male

Reported by a physician from United States on 2012-03-07

Patient: 54 year old male

Reactions: Liver Injury, Hepatic Function Abnormal, Hepatic Necrosis, Hepatic Fibrosis, Central Obesity, International Normalised Ratio Increased, Coronary Artery Disease, Post Procedural Haematoma, Liver Disorder, Liver Transplant, Tremor, Hepatitis Cholestatic, Overweight, Hepatic Encephalopathy, Hepatotoxicity, Oedema Peripheral

Drug(s) suspected as cause:
Isoniazid



Possible Isoniazid side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-01-31

Patient: 70 year old male

Reactions: Renal Disorder, Liver Disorder

Drug(s) suspected as cause:
Isoniazid
    Indication: Pulmonary Tuberculosis

Pyrazinamide
    Indication: Pulmonary Tuberculosis

Levofloxacin
    Indication: Pulmonary Tuberculosis

Other drugs received by patient: Rifampicin; Ethambutol Hydrochloride; Cycloserine



Possible Isoniazid side effects in female

Reported by a individual with unspecified qualification from Japan on 2012-01-03

Patient: female, weighing 45.0 kg (99.0 pounds)

Reactions: Hypoxia, Bronchitis, Bronchiolitis, Hepatic Enzyme Increased, Liver Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Actemra
    Indication: Rheumatoid Arthritis
    Start date: 2009-01-14
    End date: 2009-01-14

Actemra
    Start date: 2009-02-18
    End date: 2009-02-18

Actemra
    Start date: 2009-05-13
    End date: 2009-05-13

Actemra

Isoniazid
    Dosage: dose form: peroral agent
    Administration route: Oral
    Indication: Antibiotic Prophylaxis
    Start date: 2008-12-17
    End date: 2009-03-13

Actemra
    Start date: 2009-07-08
    End date: 2009-07-08

Prednisolone
    Dosage: dose form: peroral agent
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Prednisolone
    Administration route: Oral

Actemra
    Start date: 2009-03-18
    End date: 2009-03-18

Actemra
    Start date: 2009-04-15
    End date: 2009-04-15

Actemra
    Start date: 2009-06-10
    End date: 2009-06-10

Other drugs received by patient: Lantus; Atelec; Sodium Azulene Sulfonate; Naboal; Azulfidine; Alendronate Sodium; Sodium Azulene Sulfonate; Amlodipine; Novorapid



Possible Isoniazid side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-23

Patient: male

Reactions: Candida Pneumonia, Drug Eruption, Pneumonia Aspiration, Hypoglycaemia, Aplastic Anaemia, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Isoniazid
    Dosage: after breakfast
    Indication: Pulmonary Tuberculosis
    Start date: 2010-05-29

Pyrazinamide
    Start date: 2010-07-22
    End date: 2010-09-18

Pyrazinamide
    Dosage: after lunch
    Start date: 2010-05-29

Rifadin

Levofloxacin
    Dosage: after breakfast
    Administration route: Oral
    Indication: Pulmonary Tuberculosis

Isoniazid
    Dosage: after breakfast
    Indication: Disseminated Tuberculosis
    Start date: 2010-05-29

Isoniazid
    Dosage: after breakfast

Ethambutol Hydrochloride
    End date: 2010-06-16

Pyrazinamide
    Indication: Pulmonary Tuberculosis
    Start date: 2010-07-22
    End date: 2010-09-18

Ethambutol Hydrochloride
    Indication: Pulmonary Tuberculosis
    End date: 2010-06-16

Ethambutol Hydrochloride

Streptomycin Sulfate
    Indication: Pulmonary Tuberculosis

Pyrazinamide
    Start date: 2010-07-13
    End date: 2011-07-17

Rifadin
    Indication: Disseminated Tuberculosis

Enalapril Maleate
    Dosage: after breakfast
    Indication: Product Used FOR Unknown Indication

Pyrazinamide
    Dosage: after lunch
    Indication: Disseminated Tuberculosis

Rifadin
    Indication: Pulmonary Tuberculosis
    Start date: 2010-05-29

Epinastine Hydrochloride
    Dosage: 1 df before bedtime
    Indication: Product Used FOR Unknown Indication

Levofloxacin
    Dosage: after breakfast
    Administration route: Oral
    Indication: Disseminated Tuberculosis

Isoniazid
    Dosage: after breakfast

Pyrazinamide
    Start date: 2010-07-13
    End date: 2011-07-17

Rifadin
    Start date: 2010-05-29

Ethambutol Hydrochloride
    Indication: Extrapulmonary Tuberculosis

Streptomycin Sulfate
    Indication: Extrapulmonary Tuberculosis

Pyrazinamide
    Dosage: after lunch

Pyrazinamide
    Dosage: after lunch
    Start date: 2010-05-29

Famotidine
    Dosage: after dinner
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Gascon; Lasix; Seishoku; Albumin (Human); Lipitor; Pursennid; Heparin NA Lock; Levothyroxine Sodium; Neolamin 3B; Seishoku; Potassium Chloride; Vancomycin Hychloride; Urso 250; Kaytwo; Lasix; Seishoku; Hanp; Aldactone; Ganaton; Hicaliq; Elemenmic; Distilled Water; Pantol (Panthenol); Solu-Cortef; Lasix; Dextrose; Cortril; Seishoku; Seishoku; Gran; Magnesium Oxide; TPN Electrolytes IN Plastic Container; ALL Other Therapeutic Drugs; Tienam; Ensure; Prednisolone



Possible Isoniazid side effects in 60 year old female

Reported by a pharmacist from Japan on 2011-12-20

Patient: 60 year old female, weighing 78.0 kg (171.6 pounds)

Reactions: Liver Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Orencia
    Dosage: 23mar11: 500mg
    Indication: Rheumatoid Arthritis
    Start date: 2011-03-09
    End date: 2011-04-06

Bredinin
    Start date: 2010-04-19
    End date: 2011-05-20

Rheumatrex
    Indication: Rheumatoid Arthritis
    Start date: 2010-11-24
    End date: 2011-05-20

Isoniazid
    Indication: Tuberculosis
    Start date: 2010-03-31
    End date: 2011-05-19

Actonel
    Indication: Osteoporosis

Actarit
    Indication: Rheumatoid Arthritis

Other drugs received by patient: Aldactone; Urso 250; Prednisolone; Tocilizumab; Prednisolone; Laxoberon; Folic Acid; Rabeprazole Sodium; Foipan; Nizoral



Possible Isoniazid side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-12

Patient: 52 year old male

Reactions: Lymphadenopathy, Pyrexia, Drug Rash With Eosinophilia and Systemic Symptoms, Erythema, Liver Disorder, Eosinophilia, Lymphocyte Morphology Abnormal, Leukocytosis

Drug(s) suspected as cause:
Pyrazinamide
    Indication: Tuberculous Pleurisy

Ethambutol Hydrochloride
    Indication: Tuberculous Pleurisy

Isoniazid
    Indication: Tuberculous Pleurisy

Rifampicin
    Indication: Tuberculous Pleurisy



Possible Isoniazid side effects in 52 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-12-06

Patient: 52 year old male

Reactions: Lymphadenopathy, Pyrexia, Erythema, Drug Rash With Eosinophilia and Systemic Symptoms, Eosinophilia, Liver Disorder, Lymphocyte Morphology Abnormal, Leukocytosis

Drug(s) suspected as cause:
Rifampicin
    Indication: Tuberculous Pleurisy

Pyrazinamide
    Indication: Tuberculous Pleurisy

Isoniazid
    Indication: Tuberculous Pleurisy

Ethambutol Hydrochloride
    Indication: Tuberculous Pleurisy



Possible Isoniazid side effects in male

Reported by a consumer/non-health professional from Japan on 2011-11-16

Patient: male

Reactions: Liver Disorder

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Ciprofloxacin HCL
    Dosage: 300 mg, bid
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-05
    End date: 2010-10-08

Famotidine
    Dosage: 20 mg/day
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-07
    End date: 2010-10-08

Isoniazid
    Dosage: 0.25 g, qd
    Administration route: Oral
    Start date: 2010-10-07
    End date: 2010-10-08

Levofloxacin
    Dosage: 5 g/day
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-22
    End date: 2010-10-27

Aderoxal
    Dosage: 0.1 g, tid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-07
    End date: 2010-10-08

Isoniazid
    Dosage: 250 mg/day
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-06

Rifadin
    Dosage: 450 mg/day
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-08

Levofloxacin
    Indication: Pyrexia

Ethambutol Hydrochloride
    Dosage: 625 mg/day
    Administration route: Oral
    Indication: Pyrexia
    Start date: 2010-10-22
    End date: 2010-10-27

Other drugs received by patient: Neoparen NO. 2; Neophagen C; Physio 35; Neoparen NO. 2; Ensure; Neophagen C; Twinpal



Possible Isoniazid side effects in male

Reported by a consumer/non-health professional from Japan on 2011-11-11

Patient: male

Reactions: Liver Disorder

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Aderoxal
    Dosage: 0.1 g, tid
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-07
    End date: 2010-10-08

Rifadin
    Dosage: 450 mg/day
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-08

Isoniazid
    Dosage: 0.25 g, qd
    Administration route: Oral
    Start date: 2010-10-07
    End date: 2010-10-08

Levofloxacin
    Indication: Pyrexia

Famotidine
    Dosage: 20 mg/day
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-07
    End date: 2010-10-08

Ethambutol Hydrochloride
    Dosage: 625 mg/day
    Administration route: Oral
    Indication: Pyrexia
    Start date: 2010-10-22
    End date: 2010-10-27

Ciprofloxacin HCL
    Dosage: 300 mg, bid
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-05
    End date: 2010-10-08

Isoniazid
    Dosage: 250 mg/day
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-06

Levofloxacin
    Dosage: 5 g/day
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-22
    End date: 2010-10-27

Other drugs received by patient: Ensure; Neoparen NO. 2; Physio 35; Neoparen NO. 2; Neophagen C; Neophagen C; Twinpal



Possible Isoniazid side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-31

Patient: male

Reactions: Liver Disorder

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Rifadin
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-08

Ethambutol Hydrochloride
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-22
    End date: 2010-10-27

Aderoxal
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-07
    End date: 2010-10-08

Isoniazid
    Administration route: Oral
    Start date: 2010-10-07
    End date: 2010-10-08

Isoniazid
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-06

Levofloxacin
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-22
    End date: 2010-10-27

Ciprofloxacin
    Indication: Pulmonary Tuberculosis
    Start date: 2010-10-05
    End date: 2010-10-08

Famotidine
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2010-10-07
    End date: 2010-10-08

Other drugs received by patient: TPN; Ensure; Unknown Medication; Physio; TPN



Possible Isoniazid side effects in 86 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-27

Patient: 86 year old male

Reactions: Pneumonia, Lung Neoplasm, Purpura, Pyrexia, Liver Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Rifampicin
    Dosage: 450 mg, daily
    Administration route: Oral
    Indication: Pulmonary Tuberculosis
    Start date: 2009-07-09
    End date: 2009-07-28

Isoniazid
    Dosage: 200 mg, daily
    Indication: Pulmonary Tuberculosis
    Start date: 2009-07-09
    End date: 2009-07-28

Other drugs received by patient: Ethambutol Hydrochloride; Pyrazinamide; Cycloserine; Levofloxacin



Possible Isoniazid side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-24

Patient: male

Reactions: Renal Disorder, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Isoniazid
    Indication: Pulmonary Tuberculosis

Rifadin
    Indication: Pulmonary Tuberculosis

Levofloxacin
    Indication: Pulmonary Tuberculosis

Other drugs received by patient: Ethambutol Hydrochloride



Possible Isoniazid side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-20

Patient: male

Reactions: Hepatic Function Abnormal, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Isoniazid
    Indication: Pulmonary Tuberculosis

Rifadin
    Indication: Pulmonary Tuberculosis

Levofloxacin
    Indication: Pulmonary Tuberculosis

Ciprofloxacin
    Indication: Pulmonary Tuberculosis

Ethambutol Hydrochloride
    Indication: Pulmonary Tuberculosis



Possible Isoniazid side effects in 70 year old male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-18

Patient: 70 year old male

Reactions: Renal Disorder, Liver Disorder

Drug(s) suspected as cause:
Isoniazid
    Indication: Pulmonary Tuberculosis

Pyrazinamide
    Indication: Pulmonary Tuberculosis

Levofloxacin
    Indication: Pulmonary Tuberculosis

Other drugs received by patient: Ethambutol Hydrochloride; Cycloserine; Rifampin



Possible Isoniazid side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-11

Patient: male

Reactions: Death, Hepatic Function Abnormal, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Isoniazid
    Indication: Pulmonary Tuberculosis

Ethambutol Hydrochloride
    Indication: Pulmonary Tuberculosis

Levofloxacin
    Indication: Pulmonary Tuberculosis

Rifadin
    Indication: Pulmonary Tuberculosis

Ciprofloxacin
    Indication: Pulmonary Tuberculosis



Possible Isoniazid side effects in male

Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-10

Patient: male

Reactions: Renal Disorder, Liver Disorder

Adverse event resulted in: death

Drug(s) suspected as cause:
Rifadin
    Indication: Pulmonary Tuberculosis

Levofloxacin
    Indication: Pulmonary Tuberculosis

Isoniazid
    Indication: Pulmonary Tuberculosis

Other drugs received by patient: Ethambutol Hydrochloride

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