This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Hydroxyurea and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (162)
Death (50)
Life Threatening Events (10)
Disability (4)
Reports by Reaction Type
Neoplasm Malignant (29),
Death (15),
Pneumonia (12),
Skin Ulcer (8),
Acute Myeloid Leukaemia (8),
Respiratory Failure (8),
Cardiac Failure (8),
Maternal Exposure During Pregnancy (7),
Platelet Count Increased (6),
Drug Withdrawal Syndrome Neonatal (6),
Pericardial Effusion (6),
Thrombocytopenia (6)
Below are a few examples of reports where side effects / adverse reactions may be related to Hydroxyurea. For a complete list or a specific selection of reports, please use the links above.
Possible Hydroxyurea side effects in 82 year old female
Reported by a consumer/non-health professional from Russian Federation on 2012-08-24
Patient: 82 year old female
Reactions: Product Counterfeit, Drug Ineffective
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in male
Reported by a physician from United States on 2012-08-23
Patient: male, weighing 100.7 kg (221.5 pounds)
Reactions: Nausea, Dehydration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: no treatment
Indication: Squamous Cell Carcinoma
Blinded NO Treatment Received
Dosage: no treatment
Indication: Squamous Cell Carcinoma
Fluorouracil
Dosage: 1400 mg/24hrs civ over 120 hours
Indication: Squamous Cell Carcinoma
Start date: 2012-07-01
End date: 2012-07-06
Fluorouracil
Dosage: unk
Start date: 2012-07-29
Fluorouracil
Dosage: 1400 mg/24hrs civ over 120 hours
Start date: 2012-07-15
End date: 2012-07-20
Hydroxyurea
Dosage: unk
Administration route: Oral
Start date: 2012-07-29
Hydroxyurea
Dosage: 500 mg, bid
Administration route: Oral
Start date: 2012-07-15
End date: 2012-07-20
Hydroxyurea
Dosage: 500 mg, bid
Administration route: Oral
Indication: Squamous Cell Carcinoma
Start date: 2012-07-01
End date: 2012-07-06
Paclitaxel
Dosage: 228 mg qwk
Start date: 2012-07-15
End date: 2012-07-20
Paclitaxel
Dosage: unk
Start date: 2012-07-29
Paclitaxel
Dosage: 228 mg qwk
Indication: Squamous Cell Carcinoma
Start date: 2012-07-02
Placebo
Dosage: no treatment
Indication: Squamous Cell Carcinoma
Other drugs received by patient: Fentanyl; Neosporin (Neomycin Sulfate / Polymyxin B Sulfate); Senna; Bacitracin; Filgrastim; Morphine; Famotidine; Fluconazole; Eucerin; Prochlorperazine; Esomeprazole Sodium; Guaifenesin; Enoxaparin; Amoxicillin and Clavulanate Potassium; Miralax; Lidocaine; Escitalopram; Ondansetron; Rosuvastatin; Docusate; Aquaphor; Hydromorphone Hydrochloride; Nystatin
Possible Hydroxyurea side effects in
Reported by a consumer/non-health professional from Germany on 2012-08-16
Patient:
Reactions: Blood Folate Decreased
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in
Reported by a physician from Turkey on 2012-08-10
Patient:
Reactions: Death, Peripheral Sensorimotor Neuropathy, Multiple Myeloma
Adverse event resulted in: death
Drug(s) suspected as cause:
Bortezomib
Dosage: 1 mg, / day
Bortezomib
Dosage: 1.3 mg/m2 days:1,4,8,11
Indication: Multiple Myeloma
Dexamethasone
Dosage: unk, unknown
Indication: Multiple Myeloma
Hydroxyurea
Dosage: unk, unknown
Indication: Essential Thrombocythaemia
Start date: 2000-09-01
Thalidomide
Dosage: unk, unknown
Indication: Multiple Myeloma
Other drugs received by patient: Thyroid Replacement Therapy
Possible Hydroxyurea side effects in
Reported by a physician from Turkey on 2012-08-10
Patient:
Reactions: Death, Peripheral Sensorimotor Neuropathy, Multiple Myeloma
Adverse event resulted in: death
Drug(s) suspected as cause:
Bortezomib
Dosage: 1 mg, / day
Bortezomib
Dosage: 1.3 mg/m2 days:1,4,8,11
Indication: Multiple Myeloma
Dexamethasone
Dosage: unk, unknown
Indication: Multiple Myeloma
Hydroxyurea
Dosage: unk, unknown
Indication: Essential Thrombocythaemia
Start date: 2000-09-01
Thalidomide
Dosage: unk, unknown
Indication: Multiple Myeloma
Other drugs received by patient: Thyroid Replacement Therapy
Possible Hydroxyurea side effects in 50 year old male
Reported by a consumer/non-health professional from United Kingdom on 2012-08-06
Patient: 50 year old male
Reactions: Amnesia
Drug(s) suspected as cause:
Gabapentin
Hydroxyurea
Start date: 2011-01-05
Infumorph
Dosage: caps
Naproxen
Oramorph SR
Dosage: strength:oramorph10mg/5ml
Administration route: Oral
Tramadol HCL
Other drugs received by patient: Acetaminophen
Possible Hydroxyurea side effects in male
Reported by a physician from United States on 2012-08-03
Patient: male, weighing 100.7 kg (221.5 pounds)
Reactions: Nausea, Dehydration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: no treatment received
Indication: Squamous Cell Carcinoma
Blinded NO Treatment Received
Dosage: no treatment received
Indication: Squamous Cell Carcinoma
Fluorouracil
Dosage: 1400 mg/24hrs civ over 120 hours
Start date: 2012-07-15
End date: 2012-07-20
Fluorouracil
Dosage: 1400 mg/24hrs civ over 120 hours
Indication: Squamous Cell Carcinoma
Start date: 2012-07-15
End date: 2012-07-06
Hydroxyurea
Dosage: 500 mg, unk
Administration route: Oral
Indication: Squamous Cell Carcinoma
Start date: 2012-07-01
End date: 2012-07-06
Hydroxyurea
Dosage: 500 mg, unk
Administration route: Oral
Start date: 2012-07-15
End date: 2012-07-20
Paclitaxel
Dosage: 228 mg qwk
Start date: 2012-07-15
End date: 2012-07-20
Paclitaxel
Dosage: 228 mg qwk
Indication: Squamous Cell Carcinoma
Start date: 2012-07-02
Placebo
Dosage: no treatment received
Indication: Squamous Cell Carcinoma
Other drugs received by patient: Bacitracin; Fentanyl Citrate; Miralax; Escitalopram; Senna-Mint WAF; Famotidine; Filgrastim; Fluconazole; Eucerin; Aquaphor; Prochlorperazine; Ondansetron; Lidocaine; Morphine Sulfate; Amoxicillin and Clavulanate Potassium; Neosporin (Neomycin Sulfate / Polymyxin B Sulfate); Rosuvastatin
Possible Hydroxyurea side effects in 48 year old female
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-08-02
Patient: 48 year old female
Reactions: Multiple Myeloma
Adverse event resulted in: death
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in
Reported by a physician from Italy on 2012-08-01
Patient:
Reactions: Atrial Fibrillation, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Hydroxyurea
Dosage: 17.5 mg, monthly
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 1994-10-17
End date: 2002-03-01
Interferon
Dosage: 3 miu, three times per week
Indication: Essential Thrombocythaemia
Start date: 2002-05-20
End date: 2003-03-13
Other drugs received by patient possibly interacting with the suspect drug:
Anagrelide HCL
Dosage: .5 mg, 2x/day:bid
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2007-06-04
End date: 2009-10-07
Ticlopidine Hydrochloride
Dosage: 250 mg, 1x/day:qd
Administration route: Oral
Indication: Thrombocytosis
Start date: 1994-10-17
Possible Hydroxyurea side effects in 72 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-31
Patient: 72 year old female, weighing 60.0 kg (132.0 pounds)
Reactions: Left Ventricular Dysfunction, Dyspnoea, Conduction Disorder, Pulmonary Oedema
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Gemtuzumab
Dosage: 3 milligram/sq. meter
Start date: 2012-03-12
End date: 2012-03-19
Hydroxyurea
Dosage: 1500 milligram
Administration route: Oral
Start date: 2012-03-12
End date: 2012-03-22
Vidaza
Dosage: 75 milligram/sq. meter
Start date: 2012-03-12
End date: 2012-03-18
Possible Hydroxyurea side effects in 85 year old female
Reported by a consumer/non-health professional from Japan on 2012-07-31
Patient: 85 year old female
Reactions: Impaired Healing, Skin Ulcer, Pseudomonas Infection
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in 55 year old male
Reported by a physician from Sweden on 2012-07-30
Patient: 55 year old male
Reactions: Torsade DE Pointes, Electrocardiogram QT Prolonged, Cardio-Respiratory Arrest, Respiratory Depression, Arrhythmia, Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Acenocumarol
Dosage: 3 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 1996-05-23
Anagrelide Hydrochloride
Dosage: 1 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2005-10-10
Aspirin
Dosage: 100 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2006-05-05
Hydroxyurea
Dosage: 500 mg, bid
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 1997-12-05
End date: 2005-10-09
Other drugs received by patient: Atenolol; Candesartan; Gliclazide; Tamsulosin HCL
Possible Hydroxyurea side effects in 73 year old male
Reported by a consumer/non-health professional from United States on 2012-07-30
Patient: 73 year old male, weighing 81.0 kg (178.1 pounds)
Reactions: Cardiac Failure, Cardiomyopathy, Pericardial Effusion, Generalised Oedema, Cardiomegaly
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Acetylsalicylic Acid W / Dipyridamole
Dosage: 1 df daily dose
Start date: 2003-01-27
End date: 2005-03-20
Acetylsalicylic Acid W / Dipyridamole
Dosage: 2 df daily dose
Indication: Essential Thrombocythaemia
Start date: 2005-03-20
End date: 2009-09-21
Anagrelide HCL
Dosage: 2mg
Administration route: Oral
Start date: 2009-06-02
End date: 2009-09-21
Anagrelide HCL
Dosage: 1mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-11-09
End date: 2009-11-17
Anagrelide HCL
Dosage: dose of 1 mg and 3.5 mg
Administration route: Oral
Start date: 2000-06-28
End date: 2009-03-02
Aspirin
Dosage: 150mg
Administration route: Oral
Start date: 2003-01-27
End date: 2003-03-20
Aspirin
Dosage: 75mg
Administration route: Oral
Start date: 2009-12-30
End date: 2010-07-08
Aspirin
Dosage: 150mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2000-06-28
End date: 2003-01-25
Hydroxyurea
Dosage: 500mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-09-21
End date: 2009-09-22
Hydroxyurea
Dosage: 500mg
Administration route: Oral
Start date: 2009-10-12
End date: 2009-11-02
Other drugs received by patient: Citalopram Hydrobromide
Possible Hydroxyurea side effects in 55 year old male
Reported by a health professional (non-physician/pharmacist) from Spain on 2012-07-26
Patient: 55 year old male, weighing 86.0 kg (189.2 pounds)
Reactions: Hypovolaemic Shock, Myocardial Ischaemia, Anaphylactic Reaction, Encephalitis, Loss of Consciousness, Haemodynamic Instability, Tachyarrhythmia, Hypotension, Hyperglycaemia, Delirium, Anaphylactoid Shock, Areflexia, Septic Shock, Arteritis, Respiratory Depression, Neuropathy Peripheral, Cardio-Respiratory Arrest, Ventricular Tachyarrhythmia, Brain Oedema, Dizziness, Myocardial Infarction, Oxygen Saturation Decreased, Guillain-Barre Syndrome, Mydriasis, Hyponatraemia, Arrhythmia, Torsade DE Pointes, Vestibular Disorder, Ventricular Fibrillation, Embolism Arterial, Meningitis Noninfective, Neurogenic Shock, Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Acenocoumarol
Dosage: 3 mg, qd
Start date: 1996-05-23
Anagrelide HCL
Dosage: 5 mg, unk
Start date: 2006-02-08
End date: 2006-04-10
Anagrelide HCL
Dosage: 5 mg, unk
Start date: 2005-10-10
End date: 2005-12-12
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2007-02-27
End date: 2007-06-25
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2006-04-11
End date: 2006-07-28
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2005-12-13
End date: 2006-02-07
Anagrelide HCL
Dosage: 1 mg, unk
Start date: 2009-10-28
Anagrelide HCL
Dosage: 1 mg, unk
Start date: 2006-07-29
End date: 2007-02-26
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2008-07-15
End date: 2008-10-27
Anagrelide HCL
Dosage: 1 mg, unk
Start date: 2007-06-26
End date: 2008-07-14
Aspirin
Dosage: 100 mg, unk
Start date: 2006-05-05
Atenolol
Dosage: 100 mg, unk
Indication: Hypertension
Start date: 2008-01-01
Candesartan
Dosage: 8 mg, qd
Indication: Hypertension
Start date: 2008-01-01
Gliclazide
Dosage: 30 mg, unk
Indication: Diabetes Mellitus
Start date: 2008-01-01
Hydroxyurea
Dosage: 500 mg, unk
Start date: 1997-12-05
End date: 2005-10-09
Tamsulosin Hydrochloride
Dosage: 4 mg, unk
Indication: Prostatic Disorder
Start date: 2008-01-01
Possible Hydroxyurea side effects in 86 year old male
Reported by a physician from Germany on 2012-07-24
Patient: 86 year old male, weighing 90.0 kg (198.0 pounds)
Reactions: Pneumonia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Hydroxyurea
Other drugs received by patient: Aspirin; Allopurinol; Torsemide; ACC 200; Cotrim
Possible Hydroxyurea side effects in
Reported by a individual with unspecified qualification from United States on 2012-07-13
Patient:
Reactions: Adverse Drug Reaction
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in 41 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-06
Patient: 41 year old male
Reactions: Acute Myeloid Leukaemia, Myelodysplastic Syndrome, Pancytopenia
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in male
Reported by a physician from United States on 2012-07-05
Patient: male, weighing 103.2 kg (227.0 pounds)
Reactions: Pneumonia Aspiration, Dehydration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: no treatment
Indication: Head and Neck Cancer
Blinded NO Treatment Received
Dosage: no treatment
Indication: Head and Neck Cancer
Comparator Cetuximab
Dosage: 576 mg, qw
Start date: 2011-03-14
Comparator Cetuximab
Indication: Head and Neck Cancer
Fluorouracil
Indication: Head and Neck Cancer
Fluorouracil
Dosage: 1400 mg / day civ for 120 hours
Start date: 2011-03-13
End date: 2011-03-18
Hydroxyurea
Dosage: 500 mg, bid
Administration route: Oral
Start date: 2011-03-13
End date: 2011-03-18
Hydroxyurea
Administration route: Oral
Indication: Head and Neck Cancer
Placebo
Dosage: no treatment
Indication: Head and Neck Cancer
Other drugs received by patient: Senna-Mint WAF; Dulcolax; Percocet; Fentanyl; Lorazepam; Remeron; Acetaminophen; Neurontin; Claritin; Nexium; Lantus; Nasal Saline; Benadryl; M.v.i.; Lidocaine HCL Viscous; Insulin; Lidoderm; Ondansetron; Guaifenesin
Possible Hydroxyurea side effects in male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-03
Patient: male, weighing 52.8 kg (116.2 pounds)
Reactions: Large Intestine Perforation, Cellulitis, Respiratory Failure, Radiation Skin Injury
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: no treatment
Indication: Squamous Cell Carcinoma
Blinded NO Treatment Received
Dosage: no treatment
Indication: Squamous Cell Carcinoma
Cisplatin
Dosage: unk
Indication: Head and Neck Cancer
Cisplatin
Dosage: 120 mg, q21d
Start date: 2011-05-24
Comparator Cetuximab
Dosage: 400 mg, qw
Start date: 2011-07-13
Comparator Cetuximab
Dosage: 400 mg, qw
Start date: 2011-08-08
End date: 2011-08-12
Comparator Cetuximab
Dosage: 400 mg, qw
Indication: Head and Neck Cancer
Start date: 2011-06-07
Fluorouracil
Dosage: 950 mg/d over 120 hours
Start date: 2011-08-07
End date: 2011-08-12
Fluorouracil
Dosage: 975 mg/d over 120 hours
Indication: Head and Neck Cancer
Start date: 2011-07-04
End date: 2011-07-09
Hydroxyurea
Dosage: 500 mg, bid per gt
Administration route: Oral
Indication: Head and Neck Cancer
Start date: 2011-07-04
End date: 2011-07-09
Hydroxyurea
Dosage: 500 mg, bid per gt
Start date: 2011-08-07
End date: 2011-08-12
Paclitaxel
Dosage: 299.3 mg, q21 d
Indication: Head and Neck Cancer
Start date: 2012-05-24
Placebo
Dosage: no treatment
Indication: Squamous Cell Carcinoma
Other drugs received by patient: Elixir Paregorique Lipha; Nexium; Enalapril Maleate; Labetalol HCL; Lexapro; Neosporin (Neomycin Sulfate / Polymyxin B Sulfate); Dexamethasone Sodium Phosphate; Morphine; Colace; Nystatin; Ondansetron; Esomeprazole; Lorazepam; Prochlorperazine; Ciprofloxacin HCL; Oxycodone HCL; Oxycontin; Oramorph SR; Enoxaparin; Docusate
Possible Hydroxyurea side effects in male
Reported by a physician from United States on 2012-07-03
Patient: male, weighing 65.6 kg (144.3 pounds)
Reactions: Renal Injury, Dehydration
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Afinitor
Dosage: unk
Indication: Squamous Cell Carcinoma
Blinded NO Treatment Received
Dosage: unk
Indication: Squamous Cell Carcinoma
Comparator Cetuximab
Dosage: 482 mg, qw
Indication: Tongue Cancer Metastatic
Start date: 2011-06-20
End date: 2011-06-24
Decadron
Fluorouracil
Dosage: 950 mg, qd
Indication: Tongue Cancer Metastatic
Start date: 2011-06-19
End date: 2011-06-24
Hydroxyurea
Dosage: 500 mg, bid
Administration route: Oral
Indication: Tongue Cancer Metastatic
Start date: 2011-06-19
End date: 2011-06-24
Placebo
Dosage: unk
Indication: Squamous Cell Carcinoma
Other drugs received by patient: Prilosec; Senna-S (Docusate Sodium / Senna Alexandrina); Lorazepam; Morphine; Mupirocin; Ondansetron; Silvadene; Oramorph SR; Fluconazole; Lidocaine; Miralax; Esomeprazole; Peri-Colace; Guaifenesin; Fentanyl; Ibuprofen; Mylanta
Possible Hydroxyurea side effects in 73 year old male
Reported by a physician from Denmark on 2012-07-02
Patient: 73 year old male, weighing 81.0 kg (178.2 pounds)
Reactions: Anaemia, General Physical Health Deterioration, Cerebrovascular Accident, Cardiomyopathy, Generalised Oedema, Cardiomegaly, Pericardial Effusion, Cardiac Failure, Sepsis
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Anagrelide HCL
Dosage: .5 mg, bid
Administration route: Oral
Start date: 2009-11-09
End date: 2009-11-17
Anagrelide HCL
Dosage: alternating between a daily dose of 1 mg and 3.5 mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2000-06-28
End date: 2009-06-02
Anagrelide HCL
Dosage: .5 mg, qid
Administration route: Oral
Start date: 2009-06-02
End date: 2009-09-21
Aspirin
Dosage: 150 mg, qd
Administration route: Oral
Start date: 2003-01-27
End date: 2003-03-01
Aspirin
Dosage: 150 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2000-06-28
End date: 2003-01-25
Aspirin
Dosage: 75 mg, qd
Administration route: Oral
Start date: 2009-12-30
End date: 2010-07-08
Aspirin and Dipyridamole
Dosage: 1 df, bid
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2003-01-27
End date: 2005-03-01
Aspirin and Dipyridamole
Dosage: 1 df, qd
Administration route: Oral
Start date: 2005-03-01
End date: 2009-09-21
Hydroxyurea
Dosage: 500 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-09-21
End date: 2009-09-22
Hydroxyurea
Dosage: 500 mg, qd
Administration route: Oral
Start date: 2009-10-12
End date: 2009-11-02
Other drugs received by patient: Danazol; Citalopram Hydrobromide
Possible Hydroxyurea side effects in 85 year old male
Reported by a consumer/non-health professional from United States on 2012-06-29
Patient: 85 year old male, weighing 79.4 kg (174.6 pounds)
Reactions: Basosquamous Carcinoma
Drug(s) suspected as cause:
Hydroxyurea
Possible Hydroxyurea side effects in male
Reported by a physician from Denmark on 2012-06-29
Patient: male, weighing 81.0 kg (178.2 pounds)
Reactions: Cardiomegaly, Pericardial Effusion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Anagrelide HCL
Dosage: alternating between a daily dose of 1 mg and 3.5 mg
Administration route: Oral
Start date: 2000-06-28
End date: 2009-03-02
Anagrelide HCL
Dosage: 1 mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-11-09
End date: 2009-11-17
Anagrelide HCL
Dosage: 2 mg
Administration route: Oral
Start date: 2009-06-02
End date: 2009-09-21
Aspirin
Dosage: 150 mg
Administration route: Oral
Start date: 2000-06-28
End date: 2003-01-25
Aspirin
Dosage: 150 mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2003-01-27
End date: 2003-03-20
Aspirin
Dosage: 75 mg
Administration route: Oral
Start date: 2009-12-30
End date: 2010-07-08
Aspirin and Dipyridamole
Dosage: 1 df
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2005-03-01
End date: 2009-09-21
Aspirin and Dipyridamole
Dosage: strength 1df. daily dose: 2df
Administration route: Oral
Start date: 2003-01-27
End date: 2005-03-20
Hydroxyurea
Dosage: 500 mg
Administration route: Oral
Start date: 2009-09-21
End date: 2009-09-22
Hydroxyurea
Dosage: 500 mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-10-12
End date: 2009-11-02
Other drugs received by patient: Citalopram Hydrobromide
Possible Hydroxyurea side effects in 73 year old male
Reported by a consumer/non-health professional from United States on 2012-06-29
Patient: 73 year old male, weighing 81.0 kg (178.1 pounds)
Reactions: Cardiac Failure, Cardiomyopathy, Generalised Oedema, Cardiomegaly, Pericardial Effusion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Acetylsalicylic Acid W / Dipyridamole
Dosage: 2 df daily dose
Indication: Essential Thrombocythaemia
Start date: 2005-03-20
End date: 2009-09-21
Acetylsalicylic Acid W / Dipyridamole
Dosage: 1 df daily dose
Start date: 2003-01-27
End date: 2005-03-20
Anagrelide HCL
Dosage: 1mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-11-09
End date: 2009-11-17
Anagrelide HCL
Dosage: dose of 1 mg and 3.5 mg
Administration route: Oral
Start date: 2000-06-28
End date: 2009-03-02
Anagrelide HCL
Dosage: 2mg
Administration route: Oral
Start date: 2009-06-02
End date: 2009-09-21
Aspirin
Dosage: 150mg
Administration route: Oral
Start date: 2003-01-27
End date: 2003-03-20
Aspirin
Dosage: 150mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2000-06-28
End date: 2003-01-25
Aspirin
Dosage: 75mg
Administration route: Oral
Start date: 2009-12-30
End date: 2010-07-08
Hydroxyurea
Dosage: 500mg
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2009-09-21
End date: 2009-09-22
Hydroxyurea
Dosage: 500mg
Administration route: Oral
Start date: 2009-10-12
End date: 2009-11-02
Other drugs received by patient: Citalopram Hydrobromide
Possible Hydroxyurea side effects in male
Reported by a physician from Italy on 2012-06-26
Patient: male, weighing 70.0 kg (154.0 pounds)
Reactions: Cerebral Haemorrhage
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Arsenic Trioxide
Dosage: 10 milligram;
Start date: 2012-06-12
End date: 2012-06-16
Atracurium Besylate
Dosage: 80 milligram;
Start date: 2012-06-10
End date: 2012-06-17
Hydroxyurea
Dosage: 4 milligram;
Start date: 2012-06-12
End date: 2012-06-19
Other drugs received by patient: Methylprednisolone; Dexamethasone
Possible Hydroxyurea side effects in male
Reported by a physician from Germany on 2012-06-25
Patient: male, weighing 84.8 kg (186.6 pounds)
Reactions: Tumour Lysis Syndrome, Pneumonia, Coronary Artery Disease, Acute Myocardial Infarction, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Hydroxyurea
Inc424
Dosage: 15 mg, bid
Administration route: Oral
Indication: Myelofibrosis
Start date: 2012-02-28
End date: 2012-04-22
Other drugs received by patient: Metoprolol Tartrate; Levothyroxine Sodium; Clopidogrel
Possible Hydroxyurea side effects in 77 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-20
Patient: 77 year old female, weighing 80.0 kg (176.0 pounds)
Reactions: Troponin I Increased, Transfusion Reaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Gemtuzumab Ozogamicin
Dosage: 3 milligram/sq. meter
Start date: 2012-02-02
End date: 2012-02-13
Hydroxyurea
Dosage: 1500 milligram
Administration route: Oral
End date: 2012-02-05
Vidaza
Dosage: 75 milligram/sq. meter
Start date: 2012-02-02
End date: 2012-02-10
Possible Hydroxyurea side effects in 73 year old female
Reported by a health professional (non-physician/pharmacist) from Belgium on 2012-06-19
Patient: 73 year old female
Reactions: Gastrointestinal Ulcer, Gastrointestinal Perforation, Gastrointestinal Haemorrhage, Large Intestinal Ulcer, Anaemia, Thrombocytosis, Pancytopenia, Erythropenia, Gastrointestinal Obstruction
Drug(s) suspected as cause:
Anagrelide HCL
Aspirin
Dosage: 80 mg, unk
Calcium Carbonate
Cetirizine Hydrochloride
Epogen
Folic Acid
Furosemide
Hydroxyurea
Iron
Pravastatin
Sodium Bicarbonate
Vitamin B Complex CAP
Vitamin D
Possible Hydroxyurea side effects in 50 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-06-19
Patient: 50 year old male, weighing 80.0 kg (176.0 pounds)
Reactions: Aneurysm Ruptured, Essential Thrombocythaemia, Haemorrhage, Blood Disorder
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Anagrelide HCL
Dosage: unk unk, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2008-06-26
End date: 2009-01-01
Anagrelide HCL
Dosage: unk, qd
Administration route: Oral
Start date: 2009-01-01
Aspirin
Dosage: 75 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2007-04-01
End date: 2009-01-01
Hydroxyurea
Dosage: 1500 mg, qd
Administration route: Oral
Indication: Essential Thrombocythaemia
Start date: 2007-05-23
End date: 2008-06-25
Possible Hydroxyurea side effects in 55 year old male
Reported by a health professional (non-physician/pharmacist) from Spain on 2012-06-19
Patient: 55 year old male, weighing 86.0 kg (189.2 pounds)
Reactions: Hypovolaemic Shock, Anaphylactic Reaction, Myocardial Ischaemia, Encephalitis, Haemodynamic Instability, Loss of Consciousness, Meningitis, Tachyarrhythmia, Hyperglycaemia, Hypotension, Delirium, Areflexia, Septic Shock, Arteritis, Respiratory Depression, Cardio-Respiratory Arrest, Neuropathy Peripheral, Brain Oedema, Ventricular Tachyarrhythmia, Dizziness, Myocardial Infarction, Oxygen Saturation Decreased, Guillain-Barre Syndrome, Mydriasis, Hyponatraemia, Arrhythmia, Torsade DE Pointes, Vestibular Disorder, Ventricular Fibrillation, Embolism Arterial, Shock, Neurogenic Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Acenocoumarol
Dosage: 3 mg, qd
Start date: 1996-05-23
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2008-07-15
End date: 2008-10-27
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2007-02-27
End date: 2007-06-25
Anagrelide HCL
Dosage: 1 mg, unk
Start date: 2007-06-26
End date: 2008-07-14
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2006-04-11
End date: 2006-07-28
Anagrelide HCL
Dosage: 5 mg, unk
Start date: 2005-10-10
End date: 2005-12-12
Anagrelide HCL
Dosage: 1 mg, unk
Start date: 2006-07-29
End date: 2007-02-26
Anagrelide HCL
Dosage: 1.5 mg, unk
Start date: 2005-12-13
End date: 2006-02-07
Anagrelide HCL
Dosage: 5 mg, unk
Start date: 2006-02-08
End date: 2006-04-10
Anagrelide HCL
Dosage: 1 mg, unk
Start date: 2009-10-28
Aspirin
Dosage: 100 mg, unk
Start date: 2006-05-05
Atenolol
Dosage: 100 mg, unk
Indication: Hypertension
Start date: 2008-01-01
Candesartan
Dosage: 8 mg, qd
Indication: Hypertension
Start date: 2008-01-01
Gliclazide
Dosage: 30 mg, unk
Indication: Diabetes Mellitus
Start date: 2008-01-01
Hydroxyurea
Dosage: 500 mg, unk
Start date: 1997-12-05
End date: 2005-10-09
Tamsulosin HCL
Dosage: 4 mg, unk
Indication: Prostatic Disorder
Start date: 2008-01-01
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