Humalog and Life Threatening Events - Suspected Cause

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Index of reports > Life Threatening Events (57)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Humalog (Insulin Lispro) life threatening events. The selected reports were submitted to the FDA during the sample period of about a year.

Reports 1 - 30 of 57 Next >>

Possible Humalog side effects in 77 year old male

Reported by a consumer/non-health professional from United States on 2012-08-22

Patient: 77 year old male

Reactions: Hypoglycaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Saxagliptin
Indication: Type 2 Diabetes Mellitus
Start date: 2010-06-08

Lantus
Dosage: before randomization-15aug2010(30iu) 16aug2010-01nov2011(25iu/units) 02nov2011-conting(30iu/units)
Indication: Type 2 Diabetes Mellitus

Glucotrol XL
Dosage: before randomization-15nov2010(20mg) 16nov2010-27jun2011(30mg) 28jun2011-contn(20mg)
Indication: Type 2 Diabetes Mellitus

Humalog
Dosage: humalog short acting insulin before randomization-23jan2011(8iu) 24jan2012-conting(6units)
Indication: Type 2 Diabetes Mellitus

Placebo
Indication: Type 2 Diabetes Mellitus
Start date: 2010-06-08

Other drugs received by patient: Plavix; Triamcinolone; Pravastatin Sodium; Heparin; Aspirin; Carvedilol; Lasix; Sodium Chloride; Calcium Antagonist; Morphine; Nitrobid Ointment; Integrilin

Possible Humalog side effects in female

Reported by a physician from Brazil on 2012-08-21

Patient: female, weighing 61.1 kg (134.4 pounds)

Reactions: Hypoglycaemia, Loss of Consciousness

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humalog
    Dosage: 15 iu, each morning
    Start date: 2011-05-31
    End date: 2011-06-06

Humalog
    Dosage: 24 iu, other
    Start date: 2011-05-31
    End date: 2011-06-06

Humalog
    Dosage: unk, unknown
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-03-24

Humalog
Dosage: 6 iu, each evening
Start date: 2011-06-07

Humalog
Dosage: 12 iu, each morning
Start date: 2011-06-07

Humalog
Dosage: 18 iu, other
Start date: 2011-06-07

Humalog
    Dosage: 8 iu, each evening
    Start date: 2011-05-31
    End date: 2011-06-06

Other drugs received by patient: Aspirin; Metformin HCL

Possible Humalog side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Cardio-Respiratory Arrest, Pneumonia, Hypoglycaemic Unconsciousness, Blood Glucose Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humulin R
Dosage: 20 u, single
Start date: 2012-06-05

Humalog
    Dosage: 12 u, single
    Start date: 2012-06-05
    End date: 2012-06-05

Humulin R
    Dosage: 5 u, single
    Indication: Blood Glucose Increased
    Start date: 2012-06-05

Other drugs received by patient: Ipratropium Bromide; Januvia; Glipizide; Prednisone

Possible Humalog side effects in 77 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-17

Patient: 77 year old male

Reactions: Hypoglycaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Placebo
Indication: Type 2 Diabetes Mellitus
Start date: 2010-06-08

Glucotrol XL
Dosage: before randomization-15nov2010(20mg) 16nov2010-27jun2011(30mg) 28jun2011-contn(20mg)
Indication: Type 2 Diabetes Mellitus

Lantus
Dosage: before randomization-15aug2010(30iu) 16aug2010-01nov2011(25iu/units) 02nov2011-conting(30iu/units)
Indication: Type 2 Diabetes Mellitus

Humalog
Dosage: humalog short acting insulin before randomization-23jan2011(8iu) 24jan2012-conting(6units)
Indication: Type 2 Diabetes Mellitus

Saxagliptin
Indication: Type 2 Diabetes Mellitus
Start date: 2010-06-08

Other drugs received by patient: Morphine; Aspirin; Triamcinolone; Pravastatin Sodium; Heparin; Plavix; Lasix; Nitrobid Ointment; Integrilin; Sodium Chloride; Carvedilol; Calcium Antagonist

Possible Humalog side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-13

Patient: male

Reactions: Road Traffic Accident, Drug Ineffective, Paralysis, Tremor, Blood Glucose Increased, Cerebral Haemorrhage

Adverse event resulted in: life threatening event, disablity

Drug(s) suspected as cause:
Humalog

Possible Humalog side effects in female

Reported by a physician from Brazil on 2012-08-06

Patient: female, weighing 68.0 kg (149.6 pounds)

Reactions: Hypoglycaemic Coma

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humalog
    Dosage: unk
    Indication: Diabetes Mellitus
    Start date: 2011-07-26

Dulaglutide
    Dosage: 1.5 mg, weekly (1/w)
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-07-25

Other drugs received by patient: Metformin Hydrochloride

Possible Humalog side effects in 61 year old male

Reported by a physician from France on 2012-08-06

Patient: 61 year old male, weighing 98.0 kg (215.6 pounds)

Reactions: Hypoglycaemic Coma

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humalog
    Dosage: 30 iu, as needed
    Indication: Diabetes Mellitus
    Start date: 2012-05-15

Insulin Basal Analog III (Ly2605541) SUB
    Dosage: 30 iu, qd
    Indication: Diabetes Mellitus
    Start date: 2012-05-15

Other drugs received by patient: Furosemide; Venlafaxine; Atorvastatin; Nicardipine HCL; Losartan Potassium; Erythromycine / 00020901 /; Aspirin; Ezetimibe

Possible Humalog side effects in male

Reported by a physician from United States on 2012-08-01

Patient: male

Reactions: Sepsis Syndrome, Cutaneous Vasculitis, Rash Pruritic, Blood Glucose Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humalog
    Dosage: 6 u, qd
    Indication: Type 2 Diabetes Mellitus
    Start date: 2012-06-10

Humalog
Dosage: 12 u, qd
Start date: 2012-06-10

Humalog
Dosage: 10 u, qd
Start date: 2012-06-10

Other drugs received by patient: Tribenzor; Actos; Glyburide; Metoprolol Tartrate; Levaquin; Oral Antidiabetics

Possible Humalog side effects in 59 year old female

Reported by a physician from Czech Republic on 2012-07-31

Patient: 59 year old female

Reactions: Groin Abscess, Renal Failure, Shock Haemorrhagic, Pulmonary Embolism, Septic Shock, Acute Respiratory Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Metformin Hydrochloride
Indication: Type 2 Diabetes Mellitus

Enoxaparin Sodium

Humalog
Indication: Type 2 Diabetes Mellitus

Placebo
Indication: Type 2 Diabetes Mellitus

Blinded Therapy
    Indication: Type 2 Diabetes Mellitus
    Start date: 2010-12-21
    End date: 2011-12-14

Aspirin

Humulin N
Indication: Type 2 Diabetes Mellitus

Possible Humalog side effects in

Reported by a consumer/non-health professional from United States on 2012-07-27

Patient:

Reactions: Anoxia, Overdose, Hypoxic-Ischaemic Encephalopathy, Memory Impairment

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humalog

Other drugs received by patient: Lantus

Possible Humalog side effects in female

Reported by a physician from Brazil on 2012-07-23

Patient: female, weighing 61.1 kg (134.4 pounds)

Reactions: Hypoglycaemia, Loss of Consciousness

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humalog
    Dosage: 8 iu, each evening
    Start date: 2011-05-31
    End date: 2011-06-06

Humalog
    Dosage: 24 iu, other
    Start date: 2011-05-31
    End date: 2011-06-06

Humalog
Dosage: 6 iu, each evening
Start date: 2011-06-07

Humalog
    Dosage: unk, unknown
    Indication: Type 2 Diabetes Mellitus
    Start date: 2011-03-24

Humalog
    Dosage: 15 iu, each morning
    Start date: 2011-05-31
    End date: 2011-06-06

Humalog
Dosage: 12 iu, each morning
Start date: 2011-06-07

Humalog
Dosage: 18 iu, other
Start date: 2011-06-07

Other drugs received by patient: Metformin Hydrochloride; Acetylsalicylic Acid SRT

Possible Humalog side effects in male

Reported by a consumer/non-health professional from United States on 2012-07-19

Patient: male

Reactions: Multi-Organ Failure, Dysphonia, Sepsis, Coma, Intestinal Gangrene, Intestinal Obstruction, Blood Glucose Increased

Adverse event resulted in: death, life threatening event

Drug(s) suspected as cause:
Humalog
Dosage: 12 u, each evening
Indication: Diabetes Mellitus

Humalog
Dosage: 12 u, each evening

Other drugs received by patient: Lantus

Possible Humalog side effects in male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-18

Patient: male

Reactions: Hypotension, Hypoglycaemia, Bradykinesia, Sopor, Bradyphrenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Lyrica
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Tramadol HCL
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Apidra
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Humalog
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetine Hydrochloride
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Depakene
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Valium
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Other drugs received by patient: Ramipril

Possible Humalog side effects in 59 year old female

Reported by a physician from Czech Republic on 2012-07-10

Patient: 59 year old female

Reactions: Groin Abscess, Renal Failure, Shock Haemorrhagic, Pulmonary Embolism, Septic Shock, Acute Respiratory Failure

Adverse event resulted in: death, life threatening event, hospitalization

Drug(s) suspected as cause:
Enoxaparin Sodium

Humulin N
Indication: Type 2 Diabetes Mellitus

Metformin Hydrochloride
Indication: Type 2 Diabetes Mellitus

Blinded Therapy
    Indication: Type 2 Diabetes Mellitus
    Start date: 2010-12-21
    End date: 2011-12-14

Humalog
Indication: Type 2 Diabetes Mellitus

Placebo
Indication: Type 2 Diabetes Mellitus

Aspirin

Possible Humalog side effects in 40 year old male

Reported by a physician from Italy on 2012-07-10

Patient: 40 year old male

Reactions: Hypotension, Hypoglycaemia, Suicide Attempt, Bradykinesia, Bradyphrenia, Somnolence

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Lyrica
    Dosage: 300 mg, 2x/day
    Administration route: Oral
    Indication: Diabetic Neuropathy

Valium
    Dosage: 20 ml, total
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Lyrica
    Dosage: 14 iu total
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Tramadol HCL
    Dosage: 30 ml
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Humalog
    Dosage: 3 mg, total
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Apidra
    Dosage: 3 ml, total
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetine Hydrochloride
    Dosage: 56 iu, total
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Valproate Sodium
    Dosage: 60 iu, total
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Other drugs received by patient: Ramipril

Possible Humalog side effects in male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-09

Patient: male

Reactions: Hypokinesia, Intentional Overdose, Hypoglycaemia, Hypotension, Suicide Attempt, Sopor

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Humalog
    Dosage: once
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Valium
    Dosage: once
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Lyrica
    Dosage: once
    Administration route: Oral
    Indication: Diabetic Neuropathy
    Start date: 2012-05-23
    End date: 2012-05-23

Apidra
    Dosage: 100 iu/milliltre, 3 milliliters once
    Indication: Type 1 Diabetes Mellitus
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetime Hydrochloride
Indication: Suicide Attempt

Optiset
    Dosage: 3 times a day, once
    Indication: Device Therapy
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetime Hydrochloride
    Dosage: once
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication
    Start date: 2012-05-23
    End date: 2012-05-23

Depakene
    Dosage: once
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Tramadol HCL
    Dosage: once
    Administration route: Oral
    Indication: Suicide Attempt
    Start date: 2012-05-23
    End date: 2012-05-23

Lyrica
Indication: Suicide Attempt

Apidra
Indication: Suicide Attempt

Other drugs received by patient: Ramipril; Lantus

Possible Humalog side effects in 40 year old male

Reported by a physician from Italy on 2012-07-06

Patient: 40 year old male

Reactions: Hypokinesia, Intentional Overdose, Hypoglycaemia, Hypotension, Suicide Attempt, Sopor

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Lyrica
    Dosage: dose:14 unit(s)
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetine Hydrochloride
    Dosage: dose:56 unit(s)
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Valium
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Apidra Optiset
Start date: 2012-05-23
End date: 2012-05-23

Depakene
    Dosage: dose:60 unit(s)
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetine Hydrochloride
Administration route: Oral

Duloxetine Hydrochloride
    Dosage: dose:56 unit(s)
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Apidra Optiset
Dosage: dose reported as 18iu, 26iu and 26iu

Optiset
Indication: Device Therapy

Apidra Optiset
Start date: 2012-05-23
End date: 2012-05-23

Humalog
Start date: 2012-05-23
End date: 2012-05-23

Tramadol HCL
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Lyrica
Administration route: Oral

Apidra Optiset
Dosage: dose reported as 18iu, 26iu and 26iu

Optiset
Start date: 2012-05-23
End date: 2012-05-23

Duloxetine Hydrochloride
Administration route: Oral

Lyrica
    Dosage: dose:14 unit(s)
    Administration route: Oral
    Start date: 2012-05-23
    End date: 2012-05-23

Lyrica
Administration route: Oral
Indication: Diabetic Neuropathy

Other drugs received by patient: Ramipril; Lantus

Possible Humalog side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-28

Patient: male

Reactions: Parkinson's Disease, Bradycardia, Cardiac Arrest, Arrhythmia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humalog

Other drugs received by patient: Lantus; Lisinopril; Doxazosin Mesylate; Norvasc; Amlodipine; Omeprazole; Lantus; Aspirin; Lantus; Lantus; Lantus; Lantus; Lisinopril; Verapamil; Simvastatin; Metoprolol Tartrate; Paxil; Propranolol; Lantus; Simvastatin; Vitamin D; Paxil; Vitamin D; Xanax; Omeprazole; Lisinopril; Lipitor; Norvasc; Lantus; Doxazosin Mesylate; Metoprolol Tartrate

Possible Humalog side effects in male

Reported by a physician from Japan on 2012-06-28

Patient: male, weighing 50.0 kg (110.0 pounds)

Reactions: Jaundice, Hepatic Function Abnormal, Hypothyroidism

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Pradaxa
    Dosage: 220 mg
    Administration route: Oral
    Indication: Atrial Fibrillation
    Start date: 2011-07-06
    End date: 2011-09-14

Humalog
    Dosage: 18 u
    Indication: Type 1 Diabetes Mellitus
    Start date: 2011-07-04
    End date: 2011-10-03

Other drugs received by patient: Novorapid; Lantus; Apidra

Possible Humalog side effects in male

Reported by a consumer/non-health professional from United States on 2012-06-22

Patient: male

Reactions: Vomiting, Hyperhidrosis, Pallor, Glycosylated Haemoglobin Increased, Coeliac Disease, Diarrhoea, Dizziness, Apparent Life Threatening Event, Diabetic Ketoacidosis, Depression, Morbid Thoughts, Attention Deficit / Hyperactivity Disorder, Blood Glucose Increased

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humalog

Other drugs received by patient: Lantus

Possible Humalog side effects in male

Reported by a physician from Italy on 2012-06-20

Patient: male

Reactions: Hypotension, Alanine Aminotransferase Increased, Hypoglycaemia, Incorrect Dose Administered, Bradykinesia, Sopor, Overdose, Aspartate Aminotransferase Increased, Drug Administration Error, Suicide Attempt, Multiple Drug Overdose Intentional, Bradyphrenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Duloxetine Hydrochloride
    Dosage: 56 df, single
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetine Hydrochloride
Dosage: unk

Humalog
    Dosage: 3 ml, single
    Start date: 2012-05-23
    End date: 2012-05-23

Other drugs received by patient: Tramadol HCL; Pregabalin; Apidra; Diazepam; Depakene; Pregabalin; Apidra; Ramipril; Insulin Glargine

Possible Humalog side effects in male

Reported by a consumer/non-health professional from Italy on 2012-06-18

Patient: male

Reactions: Hypoglycaemia, Alanine Aminotransferase Increased, Hypotension, Incorrect Dose Administered, Bradykinesia, Sopor, Overdose, Aspartate Aminotransferase Increased, Suicide Attempt, Bradyphrenia

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Humalog
    Dosage: 3 ml, single
    Start date: 2012-05-23
    End date: 2012-05-23

Duloxetine Hydrochloride
Dosage: unk

Duloxetine Hydrochloride
    Dosage: 56 df, single
    Start date: 2012-05-23
    End date: 2012-05-23

Other drugs received by patient: Diazepam; Pregabalin; Depakene; Insulin Glargine; Apidra; Ramipril; Tramadol HCL; Apidra; Pregabalin

Possible Humalog side effects in 40 year old male

Reported by a physician from Italy on 2012-06-18

Patient: 40 year old male

Reactions: Hypoglycaemia, Hypotension, Suicide Attempt, Bradykinesia, Bradyphrenia, Somnolence