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Herceptin (Trastuzumab) - Fatigue - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Fatigue (60)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Herceptin (Trastuzumab) where reactions include fatigue. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 60   Next >>

Possible Herceptin side effects in

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-20

Patient:

Reactions: Abdominal Pain, Vomiting, Hypersensitivity, Nausea, Skin Toxicity, Mucosal Inflammation, Fatigue, Diarrhoea, Hepatotoxicity, Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lapatinib
    Dosage: arm b
    Administration route: Oral
    Indication: Breast Cancer

Cyclophosphamide
    Indication: Breast Cancer

Lapatinib
    Dosage: arm c
    Administration route: Oral

Herceptin
    Dosage: loading dose
    Indication: Breast Cancer

Herceptin
    Dosage: maintenance dose

Fluorouracil
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer

Epirubicin
    Indication: Breast Cancer



Possible Herceptin side effects in male

Reported by a physician from Korea, Republic of on 2012-08-16

Patient: male, weighing 55.0 kg (121.0 pounds)

Reactions: Pneumonia Fungal, Fatigue, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Xeloda
    Dosage: date of most recent dose prior to sae: 31/jan/2012
    Administration route: Oral
    Indication: Gastric Cancer
    Start date: 2011-12-21

Herceptin
    Dosage: date of most recent dose prior to sae: 18/jan/2012, 330 mg
    Indication: Gastric Cancer
    Start date: 2011-12-21

Pertuzumab
    Dosage: date of most recent dose prior to sae: 18/jan/2012, 840 mg
    Indication: Gastric Cancer
    Start date: 2011-12-21

Cisplatin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Other drugs received by patient: Ramosetron; Artemisia Asiatica; Potassium Phosphate, Monobasic; Potassium Phosphate, Monobasic; Tramadol HCL; Albumin; Pethidine HCL; Phytonadione; Tranexamic Acid; Potassium Chloride; Potassium Phosphate, Monobasic; Albumin; Fresh Frozen Plasma; Tetracosactrin; Aprepitant; Dexamethasone; Loperamide Oxide; Megestrol Acetate; Potassium Chloride; Potassium Chloride; Potassium Phosphate, Monobasic; Albumin; Dihydrocodeine Bitartrate INJ; Methylprednisolone Sodium Succinate; Ramosetron; Lactobacillus Acidophilus; Joulie's Solution; Potassium Phosphate, Monobasic; Esomeprazole; Esomeprazole; RED Blood Cells; Aprepitant; Chlorpheniramine Maleate; Ranitidine; Ultracet; Potassium Chloride; Esomeprazole; Pethidine HCL; Remifentanil; Famotidine; Potassium Phosphate, Monobasic; Lenograstim; Bisacodyl; Magnesium Sulfate; Sodium Bicarbonate; Potassium Phosphate, Monobasic; Esomeprazole; Tramadol HCL; Albumin; Morphine HCL; Chlorpheniramine Maleate; Pethidine HCL; Dexamethasone; Potassium Chloride; Potassium Chloride; Potassium Phosphate, Monobasic; Potassium Phosphate, Monobasic; Potassium Phosphate, Monobasic; Fresh Frozen Plasma; Ketoprofen; Fentanyl Citrate



Possible Herceptin side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-08-07

Patient: male, weighing 82.2 kg (180.8 pounds)

Reactions: White Blood Cell Count Decreased, Hepatic Mass, Blood Pressure Increased, Fatigue, Arthralgia, Eosinophil Count Increased, Lymphocyte Count Decreased

Adverse event resulted in: disablity

Drug(s) suspected as cause:
Herceptin
    Start date: 2011-07-22

Herceptin
    Start date: 2011-02-09

Herceptin
    Start date: 2011-06-01

Herceptin
    Start date: 2011-06-22

Herceptin
    Start date: 2011-08-10

Herceptin
    Indication: Metastatic Gastric Cancer
    Start date: 2011-01-19

Other drugs received by patient: Avalide; Pantoprazole; Senokot; Avalide; Docusate; Pantoprazole Sodium; Dilaudid; Solucort



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-08-01

Patient: female, weighing 75.4 kg (165.8 pounds)

Reactions: Vomiting, Lung Disorder, Neuropathy Peripheral, Fatigue, Hepatic Neoplasm Malignant, Ejection Fraction Decreased, Asthenia

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Gemcitabine; Carboplatin; Taxotere; Navelbine



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-27

Patient: female

Reactions: Chest Discomfort, Dyspnoea, Varicella, Pallor, Tremor, Blood Glucose Decreased, Fatigue, Onychoclasis, Cold Sweat

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-07-19

Patient: female

Reactions: Weight Decreased, Pulmonary Embolism, Pyrexia, Hyperhidrosis, Cardiac Disorder, Intestinal Perforation, Dyspepsia, Proteinuria, Epistaxis, Gingival Bleeding, Anaemia, Cardiomyopathy, Neutropenia, Hypersensitivity, Bone Pain, Pain, Chills, Skin Reaction, Abdominal Pain Upper, Polyneuropathy, Myalgia, Fatigue, Oedema, Dizziness, Myocardial Infarction, Nail Toxicity, Thrombocytopenia, Decreased Appetite, Vomiting, Dyspnoea, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Cerebrovascular Accident, Dysgeusia, Mucosal Inflammation, Anxiety, Diarrhoea, Impaired Healing, Arthralgia, Hypertension, Asthenia, Leukopenia

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer

Xeloda
    Indication: Breast Cancer



Possible Herceptin side effects in

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-19

Patient:

Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite

Drug(s) suspected as cause:
Gemcitabine Hydrochloride
    Dosage: on days 1 and 8 every 21 days
    Indication: Breast Cancer

Herceptin
    Dosage: within 2 weeks after curative surgery until 52 weeks of therapy was completed

Paclitaxel
    Dosage: over 1 h on days 1 and 8 every 21 days
    Indication: Breast Cancer

Herceptin
    Dosage: over 90 min on day 1
    Indication: Breast Cancer

Herceptin
    Dosage: over 30 min weekly



Possible Herceptin side effects in

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-07-18

Patient:

Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Decreased Appetite, Leukopenia

Drug(s) suspected as cause:
Paclitaxel
    Indication: Breast Cancer

Paclitaxel
    Dosage: dosages were modified to one step lower than the previous level after withholding treatment

Gemcitabine Hydrochloride
    Indication: Breast Cancer

Herceptin
    Dosage: over 90 min on day 1, followed by 2 mg/kg over 30 min weekly, for a total of 18 doses
    Indication: Breast Cancer

Herceptin
    Dosage: after curative surgery until 52 weeks of therapy was completed.

Gemcitabine Hydrochloride
    Dosage: dosages were modified to one step lower than the previous level after withholding treatment



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-07-11

Patient: female, weighing 135.2 kg (297.4 pounds)

Reactions: Nausea, Hyperhidrosis, Loss of Consciousness, Burning Sensation, Fatigue, Syncope, Dehydration, Dizziness, Asthenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 900 mg

Taxotere
    Dosage: 188 mg

Herceptin
    Dosage: 278 mg



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-06

Patient: female, weighing 56.8 kg (124.9 pounds)

Reactions: Fatigue, Arthropathy, Neck Pain, Dysphonia, Mitral Valve Incompetence, Loose Tooth, Vocal Cord Paralysis, Cough

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Percocet; Salagen; Femara; Zometa



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-06-26

Patient: female, weighing 56.8 kg (124.9 pounds)

Reactions: Vocal Cord Paralysis, Arthropathy, Fatigue, Neck Pain, Dysphonia, Mitral Valve Incompetence, Loose Tooth, Cough

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Zometa; Femara; Percocet; Salagen



Possible Herceptin side effects in

Reported by a individual with unspecified qualification from United States on 2012-06-19

Patient:

Reactions: Thrombosis, Headache, Device Related Infection, Peripheral Sensory Neuropathy, Pericardial Effusion, Malaise, Dyspepsia, Granulocytopenia, Hypoxia, Pneumonitis, Blood Alkaline Phosphatase Increased, Hypotension, Anaemia, Hyperglycaemia, Dehydration, Neutropenia, Pain, Bone Pain, Hypokalaemia, Neutropenic Infection, Postoperative Wound Infection, Fatigue, Chest Pain, Depression, Lethargy, Vomiting, Dyspnoea, Lymphopenia, Alanine Aminotransferase Increased, Muscular Weakness, Febrile Neutropenia, Hypophosphataemia, Syncope, Arthralgia, Diarrhoea, Ejection Fraction Decreased, Hypermagnesaemia, Respiratory Tract Infection, Leukopenia, Infection

Drug(s) suspected as cause:
Vinorelbine Tartrate
    Dosage: on day 8 and 15 of the 21 days cycle
    Indication: Breast Cancer Metastatic

Herceptin

Docetaxel
    Indication: Breast Cancer Metastatic

Herceptin
    Indication: Breast Cancer Metastatic



Possible Herceptin side effects in 60 year old female

Reported by a individual with unspecified qualification from United States on 2012-06-01

Patient: 60 year old female, weighing 79.7 kg (175.3 pounds)

Reactions: Fatigue, Diarrhoea, Dehydration, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tarceva
    Administration route: Oral
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer



Possible Herceptin side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-31

Patient: female, weighing 80.8 kg (177.8 pounds)

Reactions: White Blood Cell Count Decreased, Vomiting, Fatigue, Nausea, Alopecia, Dizziness, Depression, Constipation

Drug(s) suspected as cause:
Herceptin
    Start date: 2012-04-19

Herceptin
    Indication: Breast Cancer
    Start date: 2012-03-08

Herceptin
    Start date: 2012-03-29

Other drugs received by patient: Omeprazole; Carboplatin; Nystatin; Docetaxel; Dexamethasone; Prochlorperazine; Trazodone HCL; Ciprofloxacin HCL; Paxil



Possible Herceptin side effects in

Reported by a health professional (non-physician/pharmacist) from Korea, Republic of on 2012-05-30

Patient:

Reactions: Stomatitis, Alanine Aminotransferase Increased, Febrile Neutropenia, Fatigue, Aspartate Aminotransferase Increased, Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite

Drug(s) suspected as cause:
Paclitaxel
    Dosage: dosages were modified to one step lower than the previous level after withholding treatment

Gemcitabine Hydrochloride
    Indication: Breast Cancer

Herceptin
    Dosage: over 90 min on day 1, followed by 2 mg/kg over 30 min weekly, for a total of 18 doses
    Indication: Breast Cancer

Herceptin
    Dosage: after curative surgery until 52 weeks of therapy was completed.

Paclitaxel
    Indication: Breast Cancer

Gemcitabine Hydrochloride
    Dosage: dosages were modified to one step lower than the previous level after withholding treatment



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-30

Patient: female

Reactions: Pain, Pyrexia, Somnolence, Cardiac Disorder, Fatigue, Unevaluable Event, Hepatic Pain, Rash, Alcohol Poisoning, Stress, Syncope, Neoplasm Malignant, Mastectomy, Mental Disorder, Neutropenia, Feeling Abnormal, Asthenia, Bite, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Taxol; Oxycodone HCL



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from Netherlands on 2012-05-30

Patient: female

Reactions: Fatigue, Pain in Extremity, Musculoskeletal Pain, Ejection Fraction Decreased, Alopecia, Musculoskeletal Chest Pain, Fluid Retention

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in 65 year old female

Reported by a consumer/non-health professional from United States on 2012-05-28

Patient: 65 year old female, weighing 81.7 kg (179.8 pounds)

Reactions: Oropharyngeal Pain, Dysgeusia, Weight Increased, Fatigue, Diarrhoea, Swelling, DRY Mouth, Ejection Fraction Decreased

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Flagyl; Taxotere; Hydrochlorothiazide; Vancomycin



Possible Herceptin side effects in 65 year old female

Reported by a consumer/non-health professional from United States on 2012-05-28

Patient: 65 year old female, weighing 80.8 kg (177.8 pounds)

Reactions: White Blood Cell Count Decreased, Fatigue, Vomiting, Nausea, Alopecia, Dizziness, Depression, Constipation

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Prochlorperazine; Docetaxel; Carboplatin; Omeprazole; Paxil



Possible Herceptin side effects in 61 year old female

Reported by a physician from United States on 2012-05-25

Patient: 61 year old female

Reactions: Blood Bilirubin Increased, White Blood Cell Count Decreased, Stomatitis, Dyspnoea, Fatigue

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: over 1hr
    Indication: Breast Cancer Metastatic
    Start date: 2005-10-05

Tarceva
    Dosage: started on cycle 1 day 3
    Administration route: Oral
    Indication: Breast Cancer Metastatic

Herceptin
    Dosage: 30 min after paclitaxel infusion iv over 30 min
    Indication: Breast Cancer Metastatic
    Start date: 2005-10-05



Possible Herceptin side effects in 62 year old female

Reported by a physician from United States on 2012-05-17

Patient: 62 year old female, weighing 67.3 kg (148.1 pounds)

Reactions: Fatigue, Blindness Unilateral

Drug(s) suspected as cause:
Herceptin
    Indication: Breast Cancer Metastatic
    Start date: 2011-11-03
    End date: 2012-05-03

Avastin
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-27

Carboplatin
    Dosage: 4 auc
    Indication: Breast Cancer Metastatic
    Start date: 2011-11-03

Other drugs received by patient: Lisinopril



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-05-11

Patient: female

Reactions: Fatigue, Diarrhoea, Nausea, Rash

Drug(s) suspected as cause:
Tykerb
    Dosage: 250mg per day
    Administration route: Oral
    Indication: Breast Cancer Metastatic
    Start date: 2009-09-19

Herceptin

Xeloda
    End date: 2011-11-01

Other drugs received by patient: Ondansetron; Ambien; Lisinopril; Toprol-XL; Effexor; Zometa



Possible Herceptin side effects in 84 year old female

Reported by a consumer/non-health professional from United States on 2012-05-11

Patient: 84 year old female

Reactions: Movement Disorder, Spinal Pain, Sciatica, Mouth Ulceration, Fatigue, Frequent Bowel Movements, Vulvovaginal Dryness, DRY Mouth, Sneezing, Milia, Back Pain, Musculoskeletal Pain, Acne, DRY Skin, Rash, Vulvovaginal Discomfort, Dysuria, Neuralgia

Drug(s) suspected as cause:
Herceptin
    Indication: Breast Cancer

Tykerb
    Dosage: 1000mg per day
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-10-06

Other drugs received by patient: Actonel; Citracal + D; Multi-Vitamins; Lovaza; Vitamin B Complex CAP



Possible Herceptin side effects in 45 year old female

Reported by a consumer/non-health professional from United States on 2012-05-11

Patient: 45 year old female, weighing 68.1 kg (149.8 pounds)

Reactions: Myalgia, Burns Second Degree, Fatigue, Pain, Burns Third Degree

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Carboplatin; Taxotere



Possible Herceptin side effects in male

Reported by a physician from Korea, Republic of on 2012-05-10

Patient: male, weighing 55.0 kg (121.0 pounds)

Reactions: Pneumonia Fungal, Fatigue, Aspergillus Test Positive, Renal Failure Acute

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Pertuzumab
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Amphotericin B
    Indication: Product Used FOR Unknown Indication

Herceptin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Cisplatin
    Dosage: date of most recent dose prior to sae: 18/jan/2012
    Indication: Gastric Cancer
    Start date: 2011-12-21

Xeloda
    Dosage: date of most recent dose prior to sae: 31/jan/2012
    Administration route: Oral
    Indication: Gastric Cancer
    Start date: 2011-12-21

Voriconazole
    Indication: Product Used FOR Unknown Indication



Possible Herceptin side effects in

Reported by a physician from United States on 2012-05-02

Patient:

Reactions: Abdominal Pain, Stomatitis, Vomiting, Dyspnoea, Nausea, Bone Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Myalgia, Fatigue, Diarrhoea, Exfoliative Rash, Dehydration, Sensory Disturbance, Nervous System Disorder, Neutropenia, Leukopenia

Drug(s) suspected as cause:
Herceptin
    Dosage: as loading dose in cycle 1 (1 cycle was of 3 weeks)
    Indication: Breast Cancer Metastatic

Xeloda
    Administration route: Oral
    Indication: Breast Cancer Metastatic

Vinorelbine Tartrate
    Indication: Breast Cancer Metastatic

Herceptin



Possible Herceptin side effects in 31 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-04-24

Patient: 31 year old female

Reactions: Central Nervous System Lesion, Anaemia, Headache, Herpes Zoster, Viith Nerve Paralysis, Fatigue, Neoplasm Malignant, Eyelid Ptosis, Spinal Disorder, Neutropenia, Lethargy

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Product Used FOR Unknown Indication

Herceptin

Herceptin

Herceptin
    Indication: Product Used FOR Unknown Indication

Herceptin

Other drugs received by patient: Paclitaxel; Vinorelbine Tartrate; Thiotepa



Possible Herceptin side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-16

Patient: female, weighing 42.0 kg (92.3 pounds)

Reactions: Fatigue, Nausea, Blood Calcium Increased, Headache, Feeling Abnormal

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-04

Patient: female, weighing 43.1 kg (94.9 pounds)

Reactions: Fatigue, Nausea, Blood Calcium Increased, Headache, Feeling Abnormal

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in

Reported by a physician from United States on 2012-04-03

Patient:

Reactions: Fatigue, Anaemia, Tumour Pain, Hypotension, Urinary Tract Infection, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: over 30 min on day 1, 8, 15, and 22 starting on week 2

Carboplatin
    Dosage: auc 2 iv over 1 hour on days 1, 8, and 15
    Indication: Breast Cancer Metastatic
    Start date: 2005-05-18

Ixabepilone
    Indication: Breast Cancer Metastatic
    Start date: 2005-05-18

Herceptin
    Dosage: over 90 min on day 1 (maintenance dose)

Herceptin
    Dosage: over 90 min on day 1, week 1 only
    Indication: Breast Cancer Metastatic
    Start date: 2005-05-18



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