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Herceptin (Trastuzumab) - Dyspnoea - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Dyspnoea (57)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Herceptin (Trastuzumab) where reactions include dyspnoea. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 57   Next >>

Possible Herceptin side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-22

Patient: male, weighing 89.9 kg (197.8 pounds)

Reactions: Vomiting, Dyspnoea, Nausea, Dehydration, Pneumomediastinum, Pneumothorax, Odynophagia, Decreased Appetite

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Oxaliplatin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Avastin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Xeloda
    End date: 2012-02-26

Avastin
    Dosage: last dose recieved on 14 feb 2012
    End date: 2012-02-14

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    End date: 2012-02-14

Xeloda
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-29

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-10
    End date: 2011-11-15

Oxaliplatin
    End date: 2012-02-14

Other drugs received by patient: Actos; Lorazepam; DTO; Prilosec; Ritalin; Toprol-XL; Potassium Chloride; Lomotil; Dexamethasone; Compazine; Prednisone TAB; Citalopram Hydrobromide; Morphine Sulfate; Lisinopril; Metoprolol Tartrate; Dicyclomine; Methylphenidate; Zofran; Oxycodone HCL; Decadron Phosphate; Bentyl; Emend



Possible Herceptin side effects in 58 year old female

Reported by a physician from China on 2012-08-14

Patient: 58 year old female

Reactions: Dyspnoea, Pleural Effusion, Pulmonary Embolism, Disease Progression

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-08

Patient: female, weighing 71.3 kg (156.8 pounds)

Reactions: White Blood Cell Count Decreased, Dyspnoea, Hypoaesthesia Oral, RED Blood Cell Count Decreased, Pain, Blood Magnesium Decreased, Muscle Spasms

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Paclitaxel; Decadron Phosphate; Vitamin D; Epogen



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-08-06

Patient: female

Reactions: Tooth Loss, Generalised Anxiety Disorder, Chronic Fatigue Syndrome, Tympanic Membrane Disorder, Chronic Obstructive Pulmonary Disease, Positron Emission Tomogram Abnormal, Nervousness, Back Pain, Hypotension, Cardiomyopathy, Osteitis, Rhinitis Allergic, Angiopathy, Superinfection, Osteoporosis, Periodontal Disease, Fall, Bone Disorder, Depression, Dyspnoea, Musculoskeletal Pain, Arthralgia, JAW Disorder, Loose Tooth, Lung Infiltration, RED Blood Cell Sedimentation Rate Increased, Vitamin D Deficiency, Gingivitis, Osteomyelitis, Headache, Cough, Bowel Movement Irregularity, Cellulitis, Pneumonia, Pain in Extremity, General Physical Health Deterioration, Micturition Urgency, Osteonecrosis, Ventricular Dysfunction, Ear Pain, Otitis Media, Attention Deficit / Hyperactivity Disorder, Purulent Discharge, Atelectasis, Soft Tissue Disorder, Mouth Ulceration, Pain, Neoplasm Progression, Periodontitis, Blood Urea Nitrogen / Creatinine Ratio Increased, Hypokinesia, Toothache, Blood Glucose Increased, Pain in JAW, RIB Fracture, Dental Caries, Urinary Tract Infection, Osteolysis, Migraine With Aura, Anxiety, Osteoarthritis, Neoplasm Malignant, Osteonecrosis of JAW, Ejection Fraction Decreased, Spinal Osteoarthritis, Bronchitis, Superior Vena Cava Syndrome, Infection, Inflammation

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Zometa
    Dosage: 4 mg, unk
    Start date: 2001-01-01
    End date: 2006-03-01

Herceptin

Other drugs received by patient: Radiation Treatment; MS Contin; Skelaxin; Lortab; Percocet; Ibuprofen (Advil); Seroquel; Xanax; Lidocaine; Cymbalta; Zoloft; Ativan; Venlafaxine; Cipro; Hydrocodone Bitartrate; Unasyn; Bactrim; Toradol; Wellbutrin; Adriamycin PFS; Chemotherapeutics NOS; Herceptin; Alprazolam; Penicillin; Morphine Sulfate; Chlorhexidine Gluconate; Promethazine; Fioricet



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-27

Patient: female

Reactions: Chest Discomfort, Dyspnoea, Varicella, Pallor, Tremor, Blood Glucose Decreased, Fatigue, Onychoclasis, Cold Sweat

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United Kingdom on 2012-07-25

Patient: female

Reactions: Dyspnoea, Chest Pain

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in female

Reported by a physician from Italy on 2012-07-24

Patient: female

Reactions: Dyspnoea, Tachycardia, Hypertensive Heart Disease, Orthopnoea, Pleural Effusion, Hypertension

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Femara



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-07-19

Patient: female

Reactions: Weight Decreased, Pulmonary Embolism, Pyrexia, Hyperhidrosis, Cardiac Disorder, Intestinal Perforation, Dyspepsia, Proteinuria, Epistaxis, Gingival Bleeding, Anaemia, Cardiomyopathy, Neutropenia, Hypersensitivity, Bone Pain, Pain, Chills, Skin Reaction, Abdominal Pain Upper, Polyneuropathy, Myalgia, Fatigue, Oedema, Dizziness, Myocardial Infarction, Nail Toxicity, Thrombocytopenia, Decreased Appetite, Vomiting, Dyspnoea, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Cerebrovascular Accident, Dysgeusia, Mucosal Inflammation, Anxiety, Diarrhoea, Impaired Healing, Arthralgia, Hypertension, Asthenia, Leukopenia

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer

Xeloda
    Indication: Breast Cancer



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-07-10

Patient: female

Reactions: Tooth Loss, Weight Decreased, Primary Sequestrum, Abdominal Pain, Pruritus, Metastases To Liver, Osteomyelitis, Tooth Infection, Erythema, Pericardial Effusion, Cardiac Disorder, Asphyxia, Haemangioma of Liver, Ecchymosis, Hypoxia, Nail Disorder, Pathological Fracture, Fluid Retention, Pneumonia, Fistula, Cellulitis, Anaemia, Paraesthesia, Decreased Interest, Hepatic Cyst, Atelectasis, Exposed Bone in JAW, Pain, Hypokalaemia, Neuropathy Peripheral, Bone Loss, Chest Pain, Onychoclasis, Pleural Effusion, Depression, Injury, Thrombocytopenia, Lymphoedema, Metastases To Lung, Emphysema, Tooth Fracture, Dyspnoea, Dental Caries, Sensation of Heaviness, Rash, Hydropneumothorax, Bronchopleural Fistula, Osteonecrosis of JAW, Diarrhoea, Impaired Healing, Ejection Fraction Decreased, JAW Disorder, Sinus Tachycardia

Drug(s) suspected as cause:
Taxotere
    Dosage: 58 mg, qw

Herceptin
    Dosage: 162 mg, qw
    End date: 2007-06-11

Zometa
    Dosage: 4 mg, qmo
    Indication: Hypercalcaemia of Malignancy
    Start date: 2003-12-01
    End date: 2007-02-01

Zometa
    Indication: Breast Cancer

Zometa
    Indication: Metastases To Bone

Other drugs received by patient: Procrit; Decadron; Zofran; Coreg; Aranesp; Femara; Faslodex; Klor-CON; Torsemide; Lisinopril; Cleocin Hydrochloride; Vicodin; Adriamycin PFS; Carboplatin



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-04

Patient: female

Reactions: Abdominal Pain, Weight Decreased, Tooth Loss, Primary Sequestrum, Pruritus, Metastases To Liver, Osteomyelitis, Tooth Infection, Erythema, Cardiac Disorder, Asphyxia, Pericardial Effusion, Haemangioma of Liver, Ecchymosis, Nail Disorder, Hypoxia, Pathological Fracture, Fluid Retention, Pneumonia, Cellulitis, Fistula, Anaemia, Decreased Interest, Paraesthesia, Atelectasis, Exposed Bone in JAW, Pain, Bone Loss, Neuropathy Peripheral, Chest Pain, Onychoclasis, Pleural Effusion, Depression, Injury, Thrombocytopenia, Metastases To Lung, Emphysema, Dyspnoea, Tooth Fracture, Dental Caries, Sensation of Heaviness, Rash, Hydropneumothorax, Bronchopleural Fistula, Diarrhoea, Osteonecrosis of JAW, Impaired Healing, Ejection Fraction Decreased, JAW Disorder, Sinus Tachycardia

Drug(s) suspected as cause:
Zometa
    Dosage: 4 mg, qmo
    Indication: Hypercalcaemia of Malignancy
    Start date: 2003-12-01
    End date: 2007-02-01

Zometa
    Indication: Breast Cancer

Herceptin
    Dosage: 162 mg, qw
    End date: 2007-06-11

Taxotere
    Dosage: 58 mg, qw

Zometa
    Indication: Metastases To Bone

Other drugs received by patient: Lisinopril; Torsemide; Decadron; Femara; Zofran; Coreg; Aranesp; Cleocin Hydrochloride; Klor-CON; Procrit; Faslodex; Adriamycin PFS; Carboplatin; Vicodin



Possible Herceptin side effects in

Reported by a individual with unspecified qualification from United States on 2012-06-19

Patient:

Reactions: Thrombosis, Headache, Device Related Infection, Peripheral Sensory Neuropathy, Pericardial Effusion, Malaise, Dyspepsia, Granulocytopenia, Hypoxia, Pneumonitis, Blood Alkaline Phosphatase Increased, Hypotension, Anaemia, Hyperglycaemia, Dehydration, Neutropenia, Pain, Bone Pain, Hypokalaemia, Neutropenic Infection, Postoperative Wound Infection, Fatigue, Chest Pain, Depression, Lethargy, Vomiting, Dyspnoea, Lymphopenia, Alanine Aminotransferase Increased, Muscular Weakness, Febrile Neutropenia, Hypophosphataemia, Syncope, Arthralgia, Diarrhoea, Ejection Fraction Decreased, Hypermagnesaemia, Respiratory Tract Infection, Leukopenia, Infection

Drug(s) suspected as cause:
Vinorelbine Tartrate
    Dosage: on day 8 and 15 of the 21 days cycle
    Indication: Breast Cancer Metastatic

Herceptin

Docetaxel
    Indication: Breast Cancer Metastatic

Herceptin
    Indication: Breast Cancer Metastatic



Possible Herceptin side effects in 61 year old female

Reported by a physician from United States on 2012-06-14

Patient: 61 year old female, weighing 83.3 kg (183.3 pounds)

Reactions: Dyspnoea, Oedema Peripheral, Localised Oedema, Pleural Effusion, Pulmonary Oedema

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Indication: Breast Cancer
    Start date: 2011-06-23
    End date: 2011-10-13

Herceptin

Cyclophosphamide
    Dosage: last dose prior to sae 13/oct/2011
    Indication: Breast Cancer
    Start date: 2011-06-23

Docetaxel
    Dosage: last dose prior to sae 13/oct/2011
    Indication: Breast Cancer
    Start date: 2011-06-23



Possible Herceptin side effects in 78 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-08

Patient: 78 year old female

Reactions: Dyspnoea, Pleural Effusion

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Aromasin
    Dosage: unk
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-07-01

Herceptin
    Dosage: unk
    Indication: Breast Cancer
    Start date: 2011-07-01
    End date: 2011-08-01

Other drugs received by patient: Lasix; Aspirin; Diltiazem HCL; Potassium Chloride; Nexium; Alendronate Sodium; Plavix; Procoralan; Crestor



Possible Herceptin side effects in 61 year old female

Reported by a physician from United States on 2012-05-25

Patient: 61 year old female

Reactions: Blood Bilirubin Increased, White Blood Cell Count Decreased, Stomatitis, Dyspnoea, Fatigue

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: over 1hr
    Indication: Breast Cancer Metastatic
    Start date: 2005-10-05

Tarceva
    Dosage: started on cycle 1 day 3
    Administration route: Oral
    Indication: Breast Cancer Metastatic

Herceptin
    Dosage: 30 min after paclitaxel infusion iv over 30 min
    Indication: Breast Cancer Metastatic
    Start date: 2005-10-05



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-05-18

Patient: female, weighing 78.6 kg (172.9 pounds)

Reactions: Dyspnoea, Hypoxia, Hyponatraemia, non-Cardiac Chest Pain, Hypokalaemia, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Tarceva
    Administration route: Oral

Herceptin

Paclitaxel
    Indication: Breast Cancer

Paclitaxel

Tarceva
    Administration route: Oral
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-05-18

Patient: female, weighing 116.0 kg (255.2 pounds)

Reactions: Dyspnoea, Chest Discomfort, Nausea, Anaemia, Bone Pain, Dehydration, Musculoskeletal Chest Pain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: 208 mg
    End date: 2011-02-01

Carboplatin
    Dosage: 780 mg
    End date: 2011-01-18

Taxotere
    Dosage: 150 mg
    End date: 2011-01-18



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-05-16

Patient: female, weighing 86.0 kg (189.2 pounds)

Reactions: Dyspnoea, Diarrhoea, Sepsis, Febrile Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Docetaxel
    Dosage: form: vials, dose level: 60 mg/m2, dose reduced.
    Indication: Breast Cancer

Herceptin
    Dosage: form: vials, dose level: 6 mg/kg,permanently discontinued
    Indication: Breast Cancer
    Start date: 2010-05-04
    End date: 2010-07-22

Carboplatin
    Dosage: form: vials, dose level 5 auc, dose reduced.
    Indication: Breast Cancer

Carboplatin
    Start date: 2010-06-15
    End date: 2010-07-22

Docetaxel
    Start date: 2010-06-15
    End date: 2010-07-22

Other drugs received by patient: Dexamethasone; Cellondan; Metoclopramide; Bisoprolol Fumarate; Loperamide; Emend



Possible Herceptin side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-14

Patient: female

Reactions: Dyspnoea, Oedema Peripheral, Chronic Obstructive Pulmonary Disease, Cardiomyopathy

Drug(s) suspected as cause:
Herceptin
    Indication: Breast Cancer

Adriamycin PFS
    Indication: Product Used FOR Unknown Indication



Possible Herceptin side effects in female

Reported by a physician from China on 2012-05-10

Patient: female, weighing 54.0 kg (118.8 pounds)

Reactions: Dyspnoea, Autoimmune Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in

Reported by a physician from United States on 2012-05-02

Patient:

Reactions: Abdominal Pain, Stomatitis, Vomiting, Dyspnoea, Nausea, Bone Pain, Palmar-Plantar Erythrodysaesthesia Syndrome, Myalgia, Fatigue, Diarrhoea, Exfoliative Rash, Dehydration, Sensory Disturbance, Nervous System Disorder, Neutropenia, Leukopenia

Drug(s) suspected as cause:
Herceptin
    Dosage: as loading dose in cycle 1 (1 cycle was of 3 weeks)
    Indication: Breast Cancer Metastatic

Xeloda
    Administration route: Oral
    Indication: Breast Cancer Metastatic

Vinorelbine Tartrate
    Indication: Breast Cancer Metastatic

Herceptin



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-30

Patient: female, weighing 84.4 kg (185.8 pounds)

Reactions: Dyspnoea, Dysphonia, Rhinorrhoea, Headache, Erythema, Infusion Related Reaction

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Carboplatin; Refluxin Antacid Product NOS; Docetaxel



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-04-24

Patient: female, weighing 62.0 kg (136.4 pounds)

Reactions: Dyspnoea, Cardiac Failure, Dilatation Ventricular, Oedema

Drug(s) suspected as cause:
Herceptin
    End date: 2011-12-07

Epirubicin
    Indication: Breast Cancer
    Start date: 2011-03-22
    End date: 2011-07-08

Herceptin
    Dosage: initial dose
    Indication: Breast Cancer
    Start date: 2011-07-27

Other drugs received by patient: Cyclophosphamide; Fluorouracil



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from Mexico on 2012-04-18

Patient: female, weighing 44.0 kg (96.8 pounds)

Reactions: Dyspnoea, Sensation of Heaviness, Rhinorrhoea, Oropharyngeal Pain, Headache, Somnolence, Bronchial Obstruction, Dysgeusia, Oedema Peripheral

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Multi-Vitamin; Metformin HCL



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-04-04

Patient: female, weighing 56.8 kg (124.9 pounds)

Reactions: Peripheral Coldness, Weight Decreased, Dyspnoea, Skin Discolouration, Wheezing

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Furosemide; Metoprolol Succinate



Possible Herceptin side effects in male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-03

Patient: male, weighing 76.0 kg (167.2 pounds)

Reactions: Dyspnoea, Vomiting, Nausea, Dehydration, Pneumomediastinum

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-10
    End date: 2011-11-15

Xeloda
    End date: 2012-02-26

Herceptin
    Dosage: last dose recieved on 14 feb 2012.
    End date: 2012-02-14

Oxaliplatin
    End date: 2012-02-14

Avastin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Xeloda
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-29

Avastin
    Dosage: last dose recieved on 14 feb 2012
    End date: 2012-02-14

Oxaliplatin
    Indication: Oesophageal Cancer Metastatic
    Start date: 2011-05-17
    End date: 2011-11-15

Other drugs received by patient: Dicyclomine; Lorazepam; Metoprolol Tartrate; Zofran; Actos; Potassium Chloride; Lisinopril; Decadron; Oxycodone HCL; Compazine; DTO; Prilosec; Lomotil; Prednisone; Methylphenidate



Possible Herceptin side effects in female

Reported by a physician from Netherlands on 2012-03-26

Patient: female

Reactions: Chest Discomfort, Dyspnoea, Hypersensitivity, Thrombophlebitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: last dose: 21-10-2011
    Indication: Breast Cancer Metastatic
    Start date: 2011-09-30

Avastin
    Dosage: last dose 21-oct-2011
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-01

Paclitaxel
    Dosage: last dose 01/oct/2011
    Indication: Breast Cancer Metastatic
    Start date: 2011-10-01

Other drugs received by patient: Mebeverine; Acetaminophen; Rabeprazole Sodium; Duspatal; Codeine; Albuterol; Tramadol HCL; Clemastine; Triamteren; Polyethylene Glycol; Levothyroxine Sodium; Levothyroxine Sodium



Possible Herceptin side effects in

Reported by a physician from Italy on 2012-03-21

Patient:

Reactions: Dyspnoea, Tachycardia, Hypertensive Heart Disease, Orthopnoea, Pleural Effusion, Hypertension

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Femara



Possible Herceptin side effects in

Reported by a physician from United States on 2012-03-16

Patient:

Reactions: Dyspnoea, Embolism, Pyrexia, Cystitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Indication: Breast Cancer
    Start date: 2011-10-24

Herceptin
    Dosage: over 30 min for 15 wks

Lapatinib
    Dosage: last dose: 19 dec2011
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2011-10-24

Herceptin
    Dosage: over 90 min wk 1
    Indication: Breast Cancer
    Start date: 2011-10-24



Possible Herceptin side effects in female

Reported by a individual with unspecified qualification from Germany on 2012-03-08

Patient: female, weighing 86.0 kg (189.2 pounds)

Reactions: Dyspnoea, Diarrhoea, Sepsis, Febrile Neutropenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: form: vials, dose level 5 auc, dose reduced.
    Indication: Breast Cancer

Herceptin
    Dosage: form: vials, dose level: 6 mg/kg,permanently discontinued
    Indication: Breast Cancer
    Start date: 2010-05-04
    End date: 2010-07-22

Docetaxel
    Dosage: form: vials, dose level: 60 mg/m2, dose reduced.
    Indication: Breast Cancer

Carboplatin
    Start date: 2010-06-15
    End date: 2010-07-22

Docetaxel
    Start date: 2010-06-15
    End date: 2010-07-22

Other drugs received by patient: Emend; Dexamethasone; Loperamide HCL; Bisoprolol Fumarate; Metoclopramide; Cellondan



Possible Herceptin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-03-07

Patient: female, weighing 58.6 kg (128.8 pounds)

Reactions: Dyspnoea, Wheezing

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Furosemide; Metoprolol Succinate



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