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Herceptin (Trastuzumab) - Anaemia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Anaemia (53)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Herceptin (Trastuzumab) where reactions include anaemia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 53   Next >>

Possible Herceptin side effects in female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-23

Patient: female, weighing 69.6 kg (153.2 pounds)

Reactions: Vomiting, Metabolic Acidosis, Diarrhoea, Nausea, Anaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Indication: Breast Cancer
    Start date: 2012-06-18
    End date: 2012-06-18

Pertuzumab
    Indication: Breast Cancer
    Start date: 2012-06-18
    End date: 2012-06-18

Docetaxel
    Indication: Breast Cancer
    Start date: 2012-06-18
    End date: 2012-06-18

Other drugs received by patient: Neulasta; Taxol



Possible Herceptin side effects in 73 year old male

Reported by a pharmacist from Japan on 2012-08-15

Patient: 73 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Pruritus, Respiratory Failure, Diarrhoea, Anaemia, Infusion Related Reaction

Drug(s) suspected as cause:
Herceptin
    Dosage: 8mg/kg
    Indication: Metastatic Gastric Cancer
    Start date: 2012-07-04
    End date: 2012-07-04

Xeloda
    Administration route: Oral
    Indication: Metastatic Gastric Cancer
    Start date: 2012-07-04
    End date: 2012-07-04

Other drugs received by patient: Lansoprazole; Ferrous Citrate; Maglax; Alloid G; Acetaminophen; Promac; Hochuekkito



Possible Herceptin side effects in

Reported by a physician from Taiwan, Province of China on 2012-08-14

Patient:

Reactions: Hypersensitivity, Vomiting, Nausea, Diarrhoea, Alopecia, Anaemia

Drug(s) suspected as cause:
Herceptin
    Dosage: loading dose, over 90 min on day 1, 1st cycle
    Indication: Breast Cancer

Herceptin
    Dosage: for 30 min on days 8 and 15, 1st cycle

Docetaxel
    Dosage: on day 1, 1st cycle
    Indication: Breast Cancer

Cisplatin
    Dosage: for 24hours 1st cycle
    Indication: Breast Cancer

Other drugs received by patient: Dexamethasone



Possible Herceptin side effects in 73 year old male

Reported by a pharmacist from Japan on 2012-08-13

Patient: 73 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Pruritus, Diarrhoea, Respiratory Failure, Anaemia, Infusion Related Reaction

Drug(s) suspected as cause:
Xeloda
    Administration route: Oral
    Indication: Metastatic Gastric Cancer
    Start date: 2012-07-04
    End date: 2012-07-04

Herceptin
    Dosage: 8mg/kg
    Indication: Metastatic Gastric Cancer
    Start date: 2012-07-04
    End date: 2012-07-04

Other drugs received by patient: Hochuekkito; Alloid G; Acetaminophen; Lansoprazole; Maglax; Promac; Ferrous Citrate



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-07-24

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Lapatinib
    Dosage: last dose prior to sae:18 jun 2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Herceptin
    Dosage: date of last dose prior to sae: 18/may/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Carboplatin
    Dosage: dose: auc 2min/ml, last dose prior to sae on: 11/jun/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Paclitaxel
    Dosage: last dose prior to sae on: 11/jun/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19

Doxorubicin Hydrochloride
    Dosage: last dose prior to sae on: 11/jun/2012
    Indication: Breast Cancer
    Start date: 2012-02-02
    End date: 2012-06-19



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-07-19

Patient: female

Reactions: Weight Decreased, Pulmonary Embolism, Pyrexia, Hyperhidrosis, Cardiac Disorder, Intestinal Perforation, Dyspepsia, Proteinuria, Epistaxis, Gingival Bleeding, Anaemia, Cardiomyopathy, Neutropenia, Hypersensitivity, Bone Pain, Pain, Chills, Skin Reaction, Abdominal Pain Upper, Polyneuropathy, Myalgia, Fatigue, Oedema, Dizziness, Myocardial Infarction, Nail Toxicity, Thrombocytopenia, Decreased Appetite, Vomiting, Dyspnoea, Nausea, Palmar-Plantar Erythrodysaesthesia Syndrome, Rash, Cerebrovascular Accident, Dysgeusia, Mucosal Inflammation, Anxiety, Diarrhoea, Impaired Healing, Arthralgia, Hypertension, Asthenia, Leukopenia

Drug(s) suspected as cause:
Avastin
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer

Xeloda
    Indication: Breast Cancer



Possible Herceptin side effects in 69 year old female

Reported by a pharmacist from Switzerland on 2012-07-16

Patient: 69 year old female

Reactions: Interstitial Lung Disease, Anaemia, Lymphopenia, Neutrophil Count Decreased, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-01-01
    End date: 2012-03-01

Taxol
    Start date: 2012-01-02
    End date: 2012-05-10

Epirubicin Hydrochloride
    Start date: 2012-01-01
    End date: 2012-03-01

Herceptin
    Start date: 2012-01-02
    End date: 2012-05-10

Other drugs received by patient: Piracetam; Phlebostasin; Betaserc; Amlodipine



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-07-10

Patient: female

Reactions: Tooth Loss, Weight Decreased, Primary Sequestrum, Abdominal Pain, Pruritus, Metastases To Liver, Osteomyelitis, Tooth Infection, Erythema, Pericardial Effusion, Cardiac Disorder, Asphyxia, Haemangioma of Liver, Ecchymosis, Hypoxia, Nail Disorder, Pathological Fracture, Fluid Retention, Pneumonia, Fistula, Cellulitis, Anaemia, Paraesthesia, Decreased Interest, Hepatic Cyst, Atelectasis, Exposed Bone in JAW, Pain, Hypokalaemia, Neuropathy Peripheral, Bone Loss, Chest Pain, Onychoclasis, Pleural Effusion, Depression, Injury, Thrombocytopenia, Lymphoedema, Metastases To Lung, Emphysema, Tooth Fracture, Dyspnoea, Dental Caries, Sensation of Heaviness, Rash, Hydropneumothorax, Bronchopleural Fistula, Osteonecrosis of JAW, Diarrhoea, Impaired Healing, Ejection Fraction Decreased, JAW Disorder, Sinus Tachycardia

Drug(s) suspected as cause:
Taxotere
    Dosage: 58 mg, qw

Herceptin
    Dosage: 162 mg, qw
    End date: 2007-06-11

Zometa
    Dosage: 4 mg, qmo
    Indication: Hypercalcaemia of Malignancy
    Start date: 2003-12-01
    End date: 2007-02-01

Zometa
    Indication: Breast Cancer

Zometa
    Indication: Metastases To Bone

Other drugs received by patient: Procrit; Decadron; Zofran; Coreg; Aranesp; Femara; Faslodex; Klor-CON; Torsemide; Lisinopril; Cleocin Hydrochloride; Vicodin; Adriamycin PFS; Carboplatin



Possible Herceptin side effects in 68 year old female

Reported by a pharmacist from Switzerland on 2012-07-09

Patient: 68 year old female

Reactions: Interstitial Lung Disease, Anaemia, Lymphopenia, Neutrophil Count Decreased, Leukopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Taxol
    Dosage: unk
    Indication: Breast Cancer in Situ
    Start date: 2012-01-02
    End date: 2012-03-01

Cyclophosphamide
    Dosage: 900 mg, cyclic
    Indication: Breast Cancer in Situ
    Start date: 2012-01-01
    End date: 2012-03-01

Taxol
    Dosage: 120 mg, weekly
    Start date: 2012-03-29
    End date: 2012-05-10

Herceptin
    Dosage: unk
    Indication: Breast Cancer in Situ
    Start date: 2012-01-02
    End date: 2012-03-01

Herceptin
    Dosage: 240 mg, 1x/day
    Start date: 2012-03-29
    End date: 2012-03-29

Herceptin
    Dosage: 120 mg, weekly
    Start date: 2012-04-05
    End date: 2012-05-10

Epirubicin Hydrochloride
    Dosage: 135 mg, cyclic
    Indication: Breast Cancer in Situ
    Start date: 2012-01-01
    End date: 2012-03-01

Other drugs received by patient: Betaserc; Fragmin; Phlebostasin; Pantoprazole Sodium; Betaserc; Nootropil; Phlebostasin; Pantoprazole Sodium; Nootropil; Amlodipin Mepha



Possible Herceptin side effects in female

Reported by a physician from Germany on 2012-07-05

Patient: female, weighing 56.0 kg (123.2 pounds)

Reactions: Anaemia, Pancytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: dose: 2 auc, last dose: 11 jun 2012
    Indication: Breast Cancer
    Start date: 2012-02-02

Herceptin
    Dosage: last dose: 18-may-2012
    Indication: Breast Cancer
    Start date: 2012-02-02

Lapatinib
    Dosage: frequency: daily, last dose prior to sae:18 jun 2012
    Administration route: Oral
    Indication: Breast Cancer
    Start date: 2012-02-02

Paclitaxel
    Dosage: last dose: 11 jun 2012
    Indication: Breast Cancer
    Start date: 2012-02-02

Doxorubicin HCL
    Dosage: last dose: 11 jun 2012
    Indication: Breast Cancer
    Start date: 2012-02-02



Possible Herceptin side effects in female

Reported by a consumer/non-health professional from United States on 2012-07-04

Patient: female

Reactions: Abdominal Pain, Weight Decreased, Tooth Loss, Primary Sequestrum, Pruritus, Metastases To Liver, Osteomyelitis, Tooth Infection, Erythema, Cardiac Disorder, Asphyxia, Pericardial Effusion, Haemangioma of Liver, Ecchymosis, Nail Disorder, Hypoxia, Pathological Fracture, Fluid Retention, Pneumonia, Cellulitis, Fistula, Anaemia, Decreased Interest, Paraesthesia, Atelectasis, Exposed Bone in JAW, Pain, Bone Loss, Neuropathy Peripheral, Chest Pain, Onychoclasis, Pleural Effusion, Depression, Injury, Thrombocytopenia, Metastases To Lung, Emphysema, Dyspnoea, Tooth Fracture, Dental Caries, Sensation of Heaviness, Rash, Hydropneumothorax, Bronchopleural Fistula, Diarrhoea, Osteonecrosis of JAW, Impaired Healing, Ejection Fraction Decreased, JAW Disorder, Sinus Tachycardia

Drug(s) suspected as cause:
Zometa
    Dosage: 4 mg, qmo
    Indication: Hypercalcaemia of Malignancy
    Start date: 2003-12-01
    End date: 2007-02-01

Zometa
    Indication: Breast Cancer

Herceptin
    Dosage: 162 mg, qw
    End date: 2007-06-11

Taxotere
    Dosage: 58 mg, qw

Zometa
    Indication: Metastases To Bone

Other drugs received by patient: Lisinopril; Torsemide; Decadron; Femara; Zofran; Coreg; Aranesp; Cleocin Hydrochloride; Klor-CON; Procrit; Faslodex; Adriamycin PFS; Carboplatin; Vicodin



Possible Herceptin side effects in

Reported by a individual with unspecified qualification from United States on 2012-06-19

Patient:

Reactions: Thrombosis, Headache, Device Related Infection, Peripheral Sensory Neuropathy, Pericardial Effusion, Malaise, Dyspepsia, Granulocytopenia, Hypoxia, Pneumonitis, Blood Alkaline Phosphatase Increased, Hypotension, Anaemia, Hyperglycaemia, Dehydration, Neutropenia, Pain, Bone Pain, Hypokalaemia, Neutropenic Infection, Postoperative Wound Infection, Fatigue, Chest Pain, Depression, Lethargy, Vomiting, Dyspnoea, Lymphopenia, Alanine Aminotransferase Increased, Muscular Weakness, Febrile Neutropenia, Hypophosphataemia, Syncope, Arthralgia, Diarrhoea, Ejection Fraction Decreased, Hypermagnesaemia, Respiratory Tract Infection, Leukopenia, Infection

Drug(s) suspected as cause:
Vinorelbine Tartrate
    Dosage: on day 8 and 15 of the 21 days cycle
    Indication: Breast Cancer Metastatic

Herceptin

Docetaxel
    Indication: Breast Cancer Metastatic

Herceptin
    Indication: Breast Cancer Metastatic



Possible Herceptin side effects in

Reported by a individual with unspecified qualification from Italy on 2012-06-05

Patient:

Reactions: Vomiting, Nausea, Anaemia, Palmar-Plantar Erythrodysaesthesia Syndrome, Diarrhoea, Neutropenia, Asthenia, Leukopenia, Deep Vein Thrombosis

Drug(s) suspected as cause:
Herceptin
    Dosage: loading dose on day 1 of each cycle
    Indication: Breast Cancer

Pegylated Liposomal Doxorubicin
    Dosage: on day 1
    Indication: Breast Cancer

Fluorouracil
    Dosage: 200 mg/m2 as a continuous infusion from day 1 through day 21 to be repeated every 21 days for 8 cour
    Indication: Breast Cancer

Herceptin
    Dosage: on day 2 of each cycle

Cisplatin
    Dosage: on day 1
    Indication: Breast Cancer



Possible Herceptin side effects in 63 year old male

Reported by a individual with unspecified qualification from United States on 2012-05-28

Patient: 63 year old male, weighing 67.4 kg (148.3 pounds)

Reactions: Anaemia, Gastric Ulcer, Gastric Haemorrhage

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Dosage: over 1 hr on days 1, 8, 15, 22, 29 and 36
    Indication: Oesophageal Adenocarcinoma
    Start date: 2012-02-13

Carboplatin
    Dosage: auc=2, last dose prior to sae 19/mar/2012
    Indication: Oesophageal Adenocarcinoma
    Start date: 2012-02-13

Herceptin
    Indication: Oesophageal Adenocarcinoma
    Start date: 2012-02-13

Herceptin
    Dosage: 19/mar/2012

Herceptin



Possible Herceptin side effects in female

Reported by a physician from United States on 2012-05-18

Patient: female, weighing 116.0 kg (255.2 pounds)

Reactions: Dyspnoea, Chest Discomfort, Nausea, Anaemia, Bone Pain, Dehydration, Musculoskeletal Chest Pain

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: 208 mg
    End date: 2011-02-01

Carboplatin
    Dosage: 780 mg
    End date: 2011-01-18

Taxotere
    Dosage: 150 mg
    End date: 2011-01-18



Possible Herceptin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-16

Patient: female

Reactions: Abdominal Pain, Vomiting, Nausea, Alanine Aminotransferase Increased, Anaemia, Pyrexia, Seroma, non-Cardiac Chest Pain, Diarrhoea, Embolism, Oedema Peripheral, Aspartate Aminotransferase Increased, Skin Infection

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Epirubicin Hydrochloride
    Dosage: over 15 mins on day 1
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-10-05

Paclitaxel
    Dosage: over 60 mins weekly
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-10-05

Herceptin
    Dosage: then 2 mg/kg over 30 mins for 11 weeks
    End date: 2010-10-05

Fluorouracil
    Dosage: on day 1
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-10-05

Herceptin
    Dosage: over 90 mins week 1,
    Indication: Breast Cancer
    Start date: 2009-11-10

Cyclophosphamide
    Dosage: over 30 mins on day 1
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-10-05



Possible Herceptin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-05-15

Patient: female

Reactions: Nausea, Embolism, Anaemia, Blood Disorder, Skin Infection, Incision Site Cellulitis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Epirubicin Hydrochloride
    Dosage: 15 min on day 1
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-04-27

Paclitaxel
    Indication: Product Used FOR Unknown Indication
    Start date: 2009-11-10
    End date: 2010-04-27

Cyclophosphamide
    Dosage: over 30 min on day1
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-04-27

Herceptin
    Dosage: over 30 min for 11 weeks

Fluorouracil
    Dosage: on day 1
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-04-27

Herceptin
    Dosage: over 90 min
    Indication: Breast Cancer
    Start date: 2009-11-10
    End date: 2010-04-27



Possible Herceptin side effects in 31 year old female

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-04-24

Patient: 31 year old female

Reactions: Central Nervous System Lesion, Anaemia, Headache, Herpes Zoster, Viith Nerve Paralysis, Fatigue, Neoplasm Malignant, Eyelid Ptosis, Spinal Disorder, Neutropenia, Lethargy

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Product Used FOR Unknown Indication

Herceptin

Herceptin

Herceptin
    Indication: Product Used FOR Unknown Indication

Herceptin

Other drugs received by patient: Paclitaxel; Vinorelbine Tartrate; Thiotepa



Possible Herceptin side effects in female

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-04-19

Patient: female

Reactions: Anaemia, Platelet Count Decreased, Neutropenia

Drug(s) suspected as cause:
Herceptin

Other drugs received by patient: Zofran; Dibase; Omeprazole



Possible Herceptin side effects in female

Reported by a physician from Brazil on 2012-04-19

Patient: female

Reactions: Anaemia, Neutropenia, Thrombocytopenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Herceptin



Possible Herceptin side effects in

Reported by a physician from United States on 2012-04-04

Patient:

Reactions: White Blood Cell Count Decreased, Vomiting, Nausea, Anaemia, Catheter Site Haemorrhage, Constipation, Faecal Volume Decreased, Embolism, Dehydration, Platelet Count Decreased, Deep Vein Thrombosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gemcitabine Hydrochloride
    Dosage: over 30 minutes on days 1 and 8
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-17

Enoxaparin Sodium
    Indication: Product Used FOR Unknown Indication

Herceptin
    Dosage: over 30-90 minutes on days 1,8,15
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-17

Fentanyl Citrate
    Indication: Product Used FOR Unknown Indication

Warfarin Sodium
    Indication: Product Used FOR Unknown Indication

Paclitaxel
    Dosage: over 3 hours on day 1
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-17

Carboplatin
    Dosage: 5auc over 15 minutes on day 1
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-17



Possible Herceptin side effects in

Reported by a physician from United States on 2012-04-03

Patient:

Reactions: Fatigue, Anaemia, Tumour Pain, Hypotension, Urinary Tract Infection, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: over 30 min on day 1, 8, 15, and 22 starting on week 2

Carboplatin
    Dosage: auc 2 iv over 1 hour on days 1, 8, and 15
    Indication: Breast Cancer Metastatic
    Start date: 2005-05-18

Ixabepilone
    Indication: Breast Cancer Metastatic
    Start date: 2005-05-18

Herceptin
    Dosage: over 90 min on day 1 (maintenance dose)

Herceptin
    Dosage: over 90 min on day 1, week 1 only
    Indication: Breast Cancer Metastatic
    Start date: 2005-05-18



Possible Herceptin side effects in male

Reported by a physician from France on 2012-03-15

Patient: male, weighing 115.0 kg (253.0 pounds)

Reactions: Anaemia, Thrombocytopenia, Haematemesis

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: day 8 cycle 1
    Indication: Gastric Cancer
    Start date: 2012-02-01

Herceptin
    Dosage: day 1 cycle 2
    Start date: 2012-02-15



Possible Herceptin side effects in female

Reported by a physician from Japan on 2012-03-02

Patient: female, weighing 52.0 kg (114.4 pounds)

Reactions: Anaemia, Small Intestinal Haemorrhage, Gastrointestinal Mucosal Disorder, Large Intestinal Haemorrhage

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Indication: Metastatic Gastric Cancer
    Start date: 2012-01-13
    End date: 2012-01-13

Herceptin
    Indication: Metastatic Gastric Cancer
    Start date: 2012-01-13
    End date: 2012-01-13



Possible Herceptin side effects in female

Reported by a lawyer from United States on 2012-02-28

Patient: female

Reactions: Tooth Loss, Abdominal Pain, Weight Decreased, Primary Sequestrum, Pruritus, Metastases To Liver, Osteomyelitis, Tooth Infection, Erythema, Cardiac Disorder, Asphyxia, Haemangioma of Liver, Ecchymosis, Nail Disorder, Hypoxia, Pathological Fracture, Fluid Retention, Fistula, Cellulitis, Pneumonia, Anaemia, Paraesthesia, Decreased Interest, Atelectasis, Exposed Bone in JAW, Pain, Bone Loss, Neuropathy Peripheral, Chest Pain, Pleural Effusion, Onychoclasis, Depression, Injury, Thrombocytopenia, Metastases To Lung, Emphysema, Tooth Fracture, Dyspnoea, Dental Caries, Sensation of Heaviness, Rash, Hydropneumothorax, Bronchopleural Fistula, Impaired Healing, Osteonecrosis of JAW, Diarrhoea, Ejection Fraction Decreased, JAW Disorder, Sinus Tachycardia

Drug(s) suspected as cause:
Zometa
    Indication: Metastases To Bone

Herceptin
    Dosage: 162 mg, qw
    End date: 2007-06-11

Zometa
    Indication: Breast Cancer

Zometa
    Dosage: 4 mg, qmo
    Indication: Hypercalcaemia of Malignancy
    Start date: 2003-12-01
    End date: 2007-02-01

Taxotere
    Dosage: 58 mg, qw

Other drugs received by patient: Adriamycin PFS; Zofran; Procrit; Carboplatin; Decadron; Torsemide; Klor-CON; Aranesp; Femara; Faslodex; Lisinopril; Vicodin; Coreg; Cleocin Hydrochloride



Possible Herceptin side effects in female

Reported by a individual with unspecified qualification from United States on 2012-02-27

Patient: female

Reactions: Hypotension, Anaemia, Febrile Neutropenia, Bacteraemia, Ejection Fraction Decreased, Bone Marrow Failure, Neutropenia, Cardiotoxicity, Thrombocytopenia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Indication: Breast Cancer

Doxorubicin HCL
    Indication: Breast Cancer

Carboplatin
    Indication: Breast Cancer

Docetaxel
    Indication: Breast Cancer

Cyclophosphamide
    Indication: Breast Cancer

Paclitaxel
    Indication: Breast Cancer



Possible Herceptin side effects in male

Reported by a physician from United States on 2012-02-21

Patient: male

Reactions: Dehydration, Anaemia, Platelet Count Decreased, Febrile Neutropenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: over 30-90 mins on day 1 , 8, 15 every 21 days.

Gemcitabine Hydrochloride
    Dosage: over 30 minutes on day 1 and 8 , every 21.
    Indication: Transitional Cell Carcinoma
    Start date: 2002-04-29

Herceptin
    Dosage: day 1 of first cycle.
    Indication: Transitional Cell Carcinoma
    Start date: 2002-04-29

Carboplatin
    Dosage: 5 auc iv over 15 mins on day 1 every 21.
    Indication: Transitional Cell Carcinoma
    Start date: 2002-04-29

Paclitaxel
    Dosage: over 3 hrs on day 1.
    Indication: Transitional Cell Carcinoma
    Start date: 2002-04-29



Possible Herceptin side effects in

Reported by a individual with unspecified qualification from Japan on 2012-02-16

Patient:

Reactions: Neurotoxicity, Left Ventricular Dysfunction, Hyperglycaemia, Oedema Peripheral, Anaemia, Febrile Neutropenia, Neutropenia, Haematotoxicity

Drug(s) suspected as cause:
Herceptin
    Dosage: loading dose. over 90 minutes on day 1
    Indication: Breast Cancer

Epirubicin Hydrochloride
    Dosage: on day 1
    Indication: Breast Cancer

Herceptin
    Dosage: maintenance dose. over 30 minutes

Cyclophosphamide
    Dosage: on day 1
    Indication: Breast Cancer

Docetaxel
    Dosage: over 1 hour on day 1
    Indication: Breast Cancer

Fluorouracil
    Dosage: on day 1
    Indication: Breast Cancer

Paclitaxel
    Dosage: over 1 hour on days 1, 8, and 15 every 3 weeks
    Indication: Breast Cancer



Possible Herceptin side effects in male

Reported by a individual with unspecified qualification from United States on 2012-02-16

Patient: male

Reactions: Groin Abscess, Neutropenic Infection, Cellulitis of Male External Genital Organ, Anaemia, Muscular Weakness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Herceptin
    Dosage: over 30-90 minutes on days 1,8, and 15

Gemcitabine Hydrochloride
    Dosage: over 30 minutes on daya 1 and 8
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-23

Paclitaxel
    Dosage: over 3 hours on day 1
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-23

Carboplatin
    Dosage: 5 auc over 15 minutes on day 1
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-23

Herceptin
    Dosage: loading dose
    Indication: Transitional Cell Carcinoma
    Start date: 2003-12-23



Possible Herceptin side effects in female

Reported by a physician from Japan on 2012-02-16

Patient: female, weighing 52.0 kg (114.4 pounds)

Reactions: Anaemia, Small Intestinal Haemorrhage, Large Intestinal Haemorrhage, Gastrointestinal Mucosal Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Paclitaxel
    Indication: Metastatic Gastric Cancer
    Start date: 2012-01-13
    End date: 2012-01-13

Herceptin
    Indication: Metastatic Gastric Cancer
    Start date: 2012-01-13
    End date: 2012-01-13



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