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Glyburide (Glyburide) - Lactic Acidosis - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Lactic Acidosis (24)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Glyburide where reactions include lactic acidosis. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Glyburide side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from China on 2012-07-10

Patient: 64 year old male

Reactions: Hypoglycaemia, Toxicity To Various Agents, Lactic Acidosis, Accidental Exposure

Drug(s) suspected as cause:
Oral Antidiabetics
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Phenformin / 00043402 /
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Metformin HCL
    Dosage: unk
    Indication: Product Used FOR Unknown Indication

Glyburide
    Dosage: unk
    Indication: Product Used FOR Unknown Indication



Possible Glyburide side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from China on 2012-06-22

Patient: 64 year old male

Reactions: Hypoglycaemia, Lactic Acidosis

Drug(s) suspected as cause:
Phenformin HCL SRC

Chinese Herbal Medicines

Glyburide

Metformin HCL



Possible Glyburide side effects in 78 year old male

Reported by a health professional (non-physician/pharmacist) from China on 2012-05-09

Patient: 78 year old male

Reactions: Lactic Acidosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Phenformin

Glyburide

Other drugs received by patient: Herbal Preparation



Possible Glyburide side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from China on 2012-05-09

Patient: 64 year old male

Reactions: Hypoglycaemia, Lactic Acidosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Metformin Hydrochloride

Glyburide

Phenformin

Other drugs received by patient: Herbal Preparation



Possible Glyburide side effects in 56 year old male

Reported by a health professional (non-physician/pharmacist) from China on 2012-05-09

Patient: 56 year old male

Reactions: Lactic Acidosis

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Phenformin HCL SRC

Glyburide

Other drugs received by patient: Herbal Preparation



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-26

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Necrosis, Hypoglycaemia, Unresponsive To Stimuli, Lactic Acidosis, Hypernatraemia, Pyrexia, Cerebral Ischaemia, Multiple Drug Overdose Intentional, Otorrhoea, Thrombocytopenia, Renal Failure Acute, Nausea, Hyperglycaemia, Hypotension, Streptococcus Test Positive, Deafness Neurosensory, Otitis Externa, Haemodialysis, Diarrhoea, Respiratory Failure, Suicide Attempt, Leukocytosis, Staphylococcus Test Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metformin Hydrochloride
    Dosage: 52 grams, oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus

Glyburide
    Dosage: 350 mg, oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus

Other drugs received by patient: Lisinopril; Gemfibrozil; Vardenafil Hydrochloride (Levitra)



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-20

Patient: 49 year old male

Reactions: Tinnitus, Tympanic Membrane Disorder, Unresponsive To Stimuli, Hypoglycaemia, Necrosis, Continuous Haemodiafiltration, Lactic Acidosis, Hypernatraemia, Ototoxicity, Cerebral Ischaemia, Multiple Drug Overdose Intentional, Thrombocytopenia, Renal Failure Acute, Nausea, Hyperglycaemia, Ear Disorder, Hypotension, Otitis Externa, Streptococcus Test Positive, Deafness Neurosensory, Toxicity To Various Agents, Respiratory Failure, Diarrhoea, Suicide Attempt, Leukocytosis, Staphylococcus Test Positive, Vertigo Positional

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metformin HCL
    Dosage: (52 gm), oral
    Administration route: Oral
    Indication: Suicide Attempt

Glyburide
    Dosage: (350 mg), oral
    Administration route: Oral
    Indication: Suicide Attempt

Other drugs received by patient: Lisinopril (Lisisnopril); Gemfibrozil; Vardenafil (Vardenafil)



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-12

Patient: 49 year old male

Reactions: Tinnitus, Hypoglycaemia, Culture Urine Positive, Lactic Acidosis, Hypernatraemia, Blood Culture Positive, Multiple Drug Overdose Intentional, Thrombocytopenia, Renal Failure Acute, Nausea, Hypotension, Hyperglycaemia, Deafness Neurosensory, Otitis Externa, Streptococcal Infection, Diarrhoea, Staphylococcal Infection, Areflexia, Vertigo, Ear Pain, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: 350 mg, oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus

Metformin Hydrochloride
    Dosage: 52 g, oral
    Administration route: Oral
    Indication: Type 2 Diabetes Mellitus



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-10

Patient: 49 year old male

Reactions: Renal Failure, Intentional Overdose, Hypoglycaemia, Hypotension, Hyperglycaemia, Otitis Externa, Deafness Neurosensory, Lactic Acidosis, Respiratory Distress

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Metformin HCL
    Dosage: 52 g, single
    Administration route: Oral
    Indication: Suicide Attempt

Glyburide
    Dosage: 350 mg, single
    Administration route: Oral
    Indication: Suicide Attempt



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-09

Patient: 49 year old male

Reactions: Intentional Overdose, Respiratory Failure, Hypoglycaemia, Hypotension, Deafness Neurosensory, Lactic Acidosis

Drug(s) suspected as cause:
Glyburide
    Dosage: 350 mg, unk
    Administration route: Oral
    Indication: Suicide Attempt

Metformin HCL
    Dosage: 52 g, unk
    Administration route: Oral
    Indication: Suicide Attempt



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-08

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Intentional Overdose, Hyperglycaemia, Hypotension, Deafness Neurosensory, Streptococcus Test Positive, Otitis Externa, Lactic Acidosis, Cerebral Ischaemia, Blood Culture Positive, Suicide Attempt, Vertigo, Thrombocytopenia, Renal Failure Acute, Staphylococcus Test Positive

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Glyburide

Metformin HCL

Other drugs received by patient: Gemfibrozil; Vancomycin; Vardenafil Hydrochloride (Levitra); Lisinopril



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-06

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Tinnitus, Unresponsive To Stimuli, Necrosis, Hypoglycaemia, Continuous Haemodiafiltration, Hypernatraemia, Lactic Acidosis, Cerebral Ischaemia, Drug Level Above Therapeutic, Multiple Drug Overdose Intentional, Tympanic Membrane Perforation, Thrombocytopenia, Renal Failure Acute, Nausea, Hypotension, Hyperglycaemia, Deafness Neurosensory, Otitis Externa, Streptococcal Infection, Respiratory Distress, Staphylococcal Infection, Diarrhoea, NO Therapeutic Response, Middle Ear Disorder, Suicide Attempt, Hypoperfusion, Leukocytosis, Vertigo Positional

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metformin HCL
    Dosage: 52 g
    Indication: Type 2 Diabetes Mellitus

Glyburide
    Dosage: 350 mg
    Indication: Type 2 Diabetes Mellitus

Other drugs received by patient: Gemfibrozil; Vardenafil Hydrochloride (Levitra); Lisinopril



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-04

Patient: 49 year old male

Reactions: Tympanic Membrane Disorder, Anion GAP Increased, Intentional Overdose, Hypoglycaemia, Necrosis, Continuous Haemodiafiltration, Lactic Acidosis, Hypernatraemia, Culture Urine Positive, Pyrexia, Blood Culture Positive, Thrombocytopenia, Renal Failure Acute, Nausea, Hypotension, Hyperglycaemia, Deafness Neurosensory, Otitis Externa, Streptococcal Infection, Respiratory Failure, Staphylococcal Infection, Diarrhoea, NO Therapeutic Response, Middle Ear Disorder, Ear Pain, Suicide Attempt, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: (350 mg), oral
    Administration route: Oral
    Indication: Suicide Attempt

Metformin HCL
    Dosage: (52 gm), oral
    Administration route: Oral
    Indication: Suicide Attempt



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-04

Patient: 49 year old male

Reactions: Intentional Overdose, Tympanic Membrane Disorder, Hypoglycaemia, Continuous Haemodiafiltration, Lactic Acidosis, Hypernatraemia, Thrombocytopenia, Renal Failure Acute, Hypotension, Hyperglycaemia, Deafness Neurosensory, Otitis Externa, Toxicity To Various Agents, Staphylococcal Infection, Respiratory Failure, Suicide Attempt, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metformin HCL
    Dosage: (52 gm), oral
    Administration route: Oral
    Indication: Suicide Attempt

Glyburide
    Dosage: (350 mg), oral
    Administration route: Oral
    Indication: Suicide Attempt



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-04-02

Patient: 49 year old male

Reactions: Intentional Overdose, Hypoglycaemia, Hypotension, Hyperglycaemia, Necrosis, Otitis Externa, Lactic Acidosis, Hypernatraemia, Alpha Haemolytic Streptococcal Infection, Staphylococcal Infection, Suicide Attempt, Leukocytosis, Thrombocytopenia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Metformin HCL
    Dosage: unk
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-28

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Intentional Overdose, Respiratory Failure, Hypotension, Hypoglycaemia, Suicide Attempt, Deafness Neurosensory, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: 350mg
    Administration route: Oral
    Indication: Intentional Overdose

Glyburide

Metformin HCL
    Dosage: 52g
    Administration route: Oral
    Indication: Intentional Overdose

Metformin HCL

Other drugs received by patient: Vardenafil Hydrochloride (Levitra); Lisinopril; Gemfibrozil



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-28

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Respiratory Failure, Intentional Overdose, Hypoglycaemia, Hypotension, Suicide Attempt, Deafness Neurosensory, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: 350mg
    Administration route: Oral
    Indication: Intentional Overdose

Glyburide

Metformin HCL
    Dosage: 52g
    Administration route: Oral
    Indication: Intentional Overdose

Metformin HCL

Other drugs received by patient: Vardenafil Hydrochloride (Levitra); Lisinopril; Gemfibrozil



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-27

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Tinnitus, Tympanic Membrane Disorder, Intentional Overdose, Anion GAP Increased, Drug Level Increased, Unresponsive To Stimuli, Hypoglycaemia, Necrosis, Deafness, Hypernatraemia, Lactic Acidosis, Pyrexia, Acoustic Stimulation Tests Abnormal, Cerebral Ischaemia, Thrombocytopenia, Renal Failure Acute, Nausea, Hypotension, Hyperglycaemia, Deafness Neurosensory, Otitis Externa, Respiratory Distress, Streptococcal Infection, Diarrhoea, Staphylococcal Infection, Vertigo, Ear Pain, Suicide Attempt, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: 350 milligrams
    Indication: Type 2 Diabetes Mellitus

Metformin HCL
    Dosage: 52 grams
    Indication: Type 2 Diabetes Mellitus

Other drugs received by patient: Gemfibrozil; Lisinopril; Vardenafil Hydrochloride (Levitra)



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-23

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Respiratory Failure, Intentional Overdose, Hypoglycaemia, Hypotension, Deafness Neurosensory, Lactic Acidosis, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide

Metformin HCL

Glyburide
    Dosage: 350 mg
    Administration route: Oral

Metformin HCL
    Dosage: 52 g
    Administration route: Oral

Other drugs received by patient: Vardenafil Hydrochloride (Levitra); Lisinopril; Gemfibrozil



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-05

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Tympanic Membrane Disorder, Intentional Overdose, Necrosis, Hypoglycaemia, Unresponsive To Stimuli, Continuous Haemodiafiltration, Lactic Acidosis, Pyrexia, Hypernatraemia, Ototoxicity, Cerebral Ischaemia, Thrombocytopenia, Renal Failure Acute, Nausea, Hypotension, Hyperglycaemia, Deafness Neurosensory, Otitis Externa, Toxicity To Various Agents, Diarrhoea, Respiratory Failure, Suicide Attempt, Hypoperfusion, Leukocytosis, Staphylococcus Test Positive

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Glyburide
    Dosage: (350 mg 1x, not recommended dose oral)
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Metformin HCL
    Dosage: (52 g 1x, not recommended dose oral)
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Vardenafil Hydrochloride (Levitra); Lisinopril; Gemfibrozil



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-23

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Tinnitus, Tympanic Membrane Disorder, Anion GAP Increased, Necrosis, Unresponsive To Stimuli, Hypoglycaemia, Continuous Haemodiafiltration, Lactic Acidosis, Hypernatraemia, Culture Urine Positive, Cerebral Ischaemia, Overdose, Blood Culture Positive, Thrombocytopenia, Renal Failure Acute, Hyperglycaemia, Hypotension, Deafness Neurosensory, Otitis Externa, Streptococcus Test Positive, Respiratory Distress, Respiratory Failure, Diarrhoea, Suicide Attempt, Vertigo, Middle Ear Disorder, Ear Pain, Leukocytosis, Staphylococcus Test Positive, Adrenal Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metformin
    Dosage: (df oral)
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Glyburide
    Dosage: (df)
    Indication: Product Used FOR Unknown Indication

Other drugs received by patient: Vardenafil Hydrochloride (Levitra); Lisinopril; Gemfibrozil



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-07

Patient: 49 year old male, weighing 74.0 kg (162.8 pounds)

Reactions: Tinnitus, Drug Level Increased, Anion GAP Increased, Intentional Overdose, Unresponsive To Stimuli, Hypoglycaemia, Blood PH Decreased, Lactic Acidosis, Hypernatraemia, Pyrexia, Bacterial Infection, Blood Creatinine Increased, Thrombocytopenia, Renal Failure Acute, Glomerular Filtration Rate Decreased, Nausea, Hypotension, Hyperglycaemia, Deafness Neurosensory, Respiratory Distress, Blood Lactic Acid Increased, Blood Glucose Decreased, Mean Arterial Pressure Decreased, Diarrhoea, Suicide Attempt, Vertigo, Ear Pain, Leukocytosis, Blood Pressure Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Metformin HCL

Metformin HCL
    Administration route: Oral
    Indication: Suicide Attempt

Glyburide
    Indication: Suicide Attempt

Glyburide
    Administration route: Oral

Other drugs received by patient: Lisinopril; Vardenafil Hydrochloride (Levitra); Heparin; Gemfibrozil



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-07

Patient: 49 year old male

Reactions: Respiratory Failure, Intentional Overdose, Hypoglycaemia, Hypotension, Deafness Neurosensory, Suicide Attempt, Lactic Acidosis

Drug(s) suspected as cause:
Glyburide
    Dosage: (350 mg), oral
    Administration route: Oral
    Indication: Suicide Attempt

Metformin HCL
    Dosage: (52 gm), oral
    Administration route: Oral
    Indication: Suicide Attempt



Possible Glyburide side effects in 49 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-02

Patient: 49 year old male

Reactions: Intentional Overdose, Respiratory Failure, Hypotension, Hypoglycaemia, Deafness Neurosensory, Lactic Acidosis

Drug(s) suspected as cause:
Metformin HCL
    Dosage: 52 g, unk
    Administration route: Oral
    Indication: Suicide Attempt

Glyburide
    Dosage: 350 mg, unk
    Administration route: Oral
    Indication: Suicide Attempt

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