DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Gleevec (Imatinib) - Side Effect Reports to FDA

 
 



This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Gleevec (Imatinib) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.

Reports by Event Outcome

All Cases (2873)
Death (1194)
Life Threatening Events (68)
Disability (71)

Reports by Reaction Type

Death (892)Neoplasm Malignant (294)Nausea (223)Diarrhoea (189)Vomiting (170)Fatigue (165)Anaemia (146)Oedema Peripheral (116)Dyspnoea (116)Pyrexia (108)Muscle Spasms (108)Neoplasm Progression (98)

Below are a few examples of reports where side effects / adverse reactions may be related to Gleevec (Imatinib). For a complete list or a specific selection of reports, please use the links above.

Possible Gleevec side effects in female

Reported by a physician from United States on 2012-08-27

Patient: female

Reactions: Adverse Drug Reaction, Cyst

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Antibiotics

Gleevec
    Dosage: 400 mg, daily
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2012-04-11



Possible Gleevec side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-27

Patient: female

Reactions: Lower Limb Fracture

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-27

Patient: male

Reactions: Hepatic Neoplasm Malignant, Neoplasm Malignant

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Prevacid; Rapamune



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-27

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-27

Patient: male

Reactions: Gastric Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in female

Reported by a physician from United States on 2012-08-24

Patient: female

Reactions: Visual Field Defect, Joint Swelling, Eye Swelling

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-24

Patient: female

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in female

Reported by a physician from United States on 2012-08-24

Patient: female

Reactions: Cerebrovascular Accident

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from South Africa on 2012-08-24

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: male

Reactions: Nipple Pain, Deafness, Gynaecomastia, Myalgia, Face Oedema, DRY Mouth, Fluid Retention, Muscle Spasms, Trismus, Middle Ear Effusion, Musculoskeletal Pain, Muscular Weakness, Musculoskeletal Discomfort, Local Swelling, Dysstasia, Joint Swelling, Arthralgia, Swelling, Eye Swelling

Drug(s) suspected as cause:
Gleevec
    Dosage: 400 mg, daily
    Administration route: Oral
    Indication: Soft Tissue Neoplasm
    Start date: 2011-06-01

Gleevec
    Dosage: 400 mg,daily
    Administration route: Oral
    Start date: 2011-06-11

Gleevec
    Dosage: 300 mg, daily
    Administration route: Oral

Gleevec
    Dosage: 200 mg/ 100 mg, daily

Other drugs received by patient: Coumadin; Inhalation; Prednisone TAB



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: male, weighing 74.8 kg (164.6 pounds)

Reactions: Viral Infection, Pyrexia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-23

Patient: female

Reactions: Abdominal Abscess

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-23

Patient: male

Reactions: Localised Infection, Impaired Healing, Wound

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec
    Dosage: 400 mg, qd
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-11-03

Gleevec
    Dosage: 600 mg, daily
    Administration route: Oral
    Start date: 2010-11-03



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-22

Patient: male

Reactions: Upper Limb Fracture

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-22

Patient: female

Reactions: Dyspnoea, Abdominal Abscess, Nausea, Pulmonary Oedema, DRY Eye

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-22

Patient: male, weighing 64.3 kg (141.5 pounds)

Reactions: Neoplasm Malignant, Neoplasm Progression

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Dulcolax; Lopressor; Vicodin HP; Furosemide; Ondansetron



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Haemorrhage, Anaemia, Melaena, Blindness

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Fish OIL; Nadolol; Omeprazole; Folic Acid; Vitron-C; Magnesium; Pravastatin; Aspirin; Allopurinol; Q10



Possible Gleevec side effects in female

Reported by a physician from United States on 2012-08-21

Patient: female

Reactions: Blood Iron Decreased, Asthenopia, Vomiting, Nausea, Anaemia, Pyrexia, Laboratory Test Abnormal, Diarrhoea, Ocular Hyperaemia, Eye Swelling, Vision Blurred, Lacrimation Increased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Digoxin

Gleevec
    Dosage: 400 mg, daily
    Administration route: Oral

Gleevec
    Dosage: 400 mg, daily
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2011-05-17

Gleevec
    Dosage: 400 mg, daily
    Administration route: Oral



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Road Traffic Accident, Clavicle Fracture, Back Injury, Joint Injury

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-21

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Glimepiride; Gabapentin; Toprol-XL; Spironolactone; Plavix; Amiodarone HCL; Warfarin Sodium; Flomax; Omeprazole; Crestor; Torsemide



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Retinal Tear

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-21

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Lupron; Marinol; Ondansetron



Possible Gleevec side effects in female

Reported by a consumer/non-health professional from United States on 2012-08-21

Patient: female

Reactions: Vomiting, Nausea, Heart Rate Increased, Pleural Effusion, Cardiac Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec
    Dosage: 300 mg, daily
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2011-10-18

Gleevec
    Dosage: 400 mg, qd
    Administration route: Oral
    Start date: 2011-10-21
    End date: 2012-03-14



Possible Gleevec side effects in female

Reported by a physician from United States on 2012-08-20

Patient: female

Reactions: Agitation, Panic Attack, Drug Interaction, Suicidal Ideation

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient possibly interacting with the suspect drug:
Depakote



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-20

Patient: male

Reactions: Death

Adverse event resulted in: death

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Vicodin; Ambien



Possible Gleevec side effects in male

Reported by a physician from United States on 2012-08-20

Patient: male

Reactions: Death, Gastrointestinal Haemorrhage, Anaemia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Gleevec



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-20

Patient: male, weighing 100.0 kg (220.0 pounds)

Reactions: Weight Decreased, Asthma, Thrombosis, Wheezing, Chills, Pyrexia, Malaise, Oedema Peripheral, Sinus Congestion, Diabetes Mellitus Inadequate Control, Decreased Appetite, Back Pain, Vein Disorder, Dyspnoea, Blast Crisis in Myelogenous Leukaemia, Nasal Congestion, Chronic Myeloid Leukaemia, Rhinitis Allergic, Neoplasm Malignant, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec
    Dosage: 400 mg, unk
    Administration route: Oral
    Start date: 2011-05-25

Gleevec
    Dosage: 400 mg, unk
    Administration route: Oral
    Start date: 2009-09-10

Gleevec
    Dosage: 400 mg, qd
    Administration route: Oral

Gleevec
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2009-09-01

Other drugs received by patient: Warfarin Sodium; Atenolol; Fexofenadine; Novolog; Uroxatral; Coumadin



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-18

Patient: male

Reactions: Back Pain, Dyspnoea, Chest Discomfort, Nausea, Headache, Muscle Tightness, Chronic Myeloid Leukaemia, Anxiety, Myalgia, Fatigue, Neoplasm Malignant, Melanocytic Naevus, Influenza Like Illness

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Gleevec

Other drugs received by patient: Claritin; Promethazine Hydrochloride; Ativan; Lorazepam



Possible Gleevec side effects in male

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: male, weighing 96.1 kg (211.5 pounds)

Reactions: Rash, Blister

Drug(s) suspected as cause:
Gleevec
    Dosage: 600 mg, daily
    Administration route: Oral
    Start date: 2011-08-21

Gleevec
    Dosage: 400 mg, qd
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia

Tasigna
    Dosage: 150 mg, bid
    Administration route: Oral
    Indication: Chronic Myeloid Leukaemia
    Start date: 2010-12-27
    End date: 2011-02-23

Tasigna
    Dosage: 300 mg, bid
    Administration route: Oral
    Start date: 2011-02-23
    End date: 2011-06-29

Other drugs received by patient: Claritin; Lisinopril; Augmentin '500'



Possible Gleevec side effects in 80 year old female

Reported by a consumer/non-health professional from United States on 2012-08-17

Patient: 80 year old female

Reactions: Eyes Sunken, Dizziness

Drug(s) suspected as cause:
Gleevec

Sprycel
    Indication: Leukaemia

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014