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Fluorouracil (Fluorouracil) - Thrombocytopenia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Thrombocytopenia (112)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Fluorouracil where reactions include thrombocytopenia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of 112   Next >>

Possible Fluorouracil side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-23

Patient: male

Reactions: Portal Hypertension, Bone Marrow Failure, Thrombocytopenia, Post Procedural Haemorrhage

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 9 cycles with oxaliplatin; then 3 cycles with oxaliplatin; then 6 cycle with oxaliplatin, irinotecan
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride
    Dosage: 6 cycles with oxaliplatin, fluorouracil
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Dosage: 9 cycles with 5-fu; then 3 cycles with 5-fu; then 6 cycles with 5-fu, irinotecan
    Indication: Colorectal Cancer Metastatic



Possible Fluorouracil side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-23

Patient: male

Reactions: Portal Hypertension, Bone Marrow Failure, Post Procedural Haemorrhage, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 9 cycles with oxaliplatin; then 3 cycles with oxaliplatin; then 6 cycle with oxaliplatin, irinotecan
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride
    Dosage: 6 cycles with oxaliplatin, fluorouracil
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Dosage: 9 cycles with 5-fu; then 3 cycles with 5-fu; then 6 cycles with 5-fu, irinotecan
    Indication: Colorectal Cancer Metastatic



Possible Fluorouracil side effects in male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-22

Patient: male

Reactions: Portal Hypertension, Bone Marrow Failure, Post Procedural Haemorrhage, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 9 cycles with oxaliplatin; then 3 cycles with oxaliplatin; then 6 cycle with oxaliplatin, irinotecan
    Indication: Colorectal Cancer Metastatic

Irinotecan Hydrochloride
    Dosage: 6 cycles with oxaliplatin, fluorouracil
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Dosage: 9 cycles with 5-fu; then 3 cycles with 5-fu; then 6 cycles with 5-fu, irinotecan
    Indication: Colorectal Cancer Metastatic



Possible Fluorouracil side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-08-17

Patient: 64 year old male

Reactions: Portal Hypertension, Intestinal Haemorrhage, Metastases To Liver, Bone Marrow Failure, Intestinal Varices, Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Indication: Adenocarcinoma

Oxaliplatin
    Indication: Adenocarcinoma

Other drugs received by patient: Neupogen



Possible Fluorouracil side effects in male

Reported by a physician from United States on 2012-08-16

Patient: male, weighing 95.0 kg (209.0 pounds)

Reactions: Haemorrhage, Gastrointestinal Stoma Complication, Tachycardia, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: 470 mg
    End date: 2012-06-26

Eloxatin
    Dosage: 144 mg
    End date: 2012-06-26

Fluorouracil
    Dosage: 4972 mg
    End date: 2012-06-26

Leucovorin Calcium
    Dosage: 860 mg
    End date: 2012-06-26



Possible Fluorouracil side effects in 27 year old female

Reported by a physician from United States on 2012-08-14

Patient: 27 year old female

Reactions: Confusional State, Weight Decreased, Stomatitis, Cerebellar Ataxia, Pyrexia, Speech Disorder, Diarrhoea, Acquired Pyrimidine Metabolism Disorder, Alopecia, Depressed Level of Consciousness, Thrombocytopenia, Leukopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 500 mg on day 8

Fluorouracil
    Dosage: 500 mg, on days 1 and 8

Fluorouracil
    Dosage: 800 mg (570 mg/m2), on day 1
    Indication: Breast Cancer

Other drugs received by patient: Methotrexate Sodium; Cytoxan; Cytoxan



Possible Fluorouracil side effects in

Reported by a physician from United States on 2012-08-13

Patient:

Reactions: Thrombosis, Pneumonia, Haemorrhage, Anaemia, Procedural Site Reaction, Ulcer Haemorrhage, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Carboplatin
    Dosage: 812 mg
    End date: 2012-07-10

Fluorouracil
    Dosage: 7160 mg
    End date: 2012-07-14



Possible Fluorouracil side effects in 43 year old female

Reported by a consumer/non-health professional from United States on 2012-08-13

Patient: 43 year old female, weighing 33.0 kg (72.6 pounds)

Reactions: Pneumonia, Respiratory Failure, Neutropenia, Septic Shock, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: day 1 every cycle,last dose on 23sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23
    End date: 2011-09-23

Fluorouracil
    Dosage: 23sp11=1d(d1ofcycle1only),30sp11-ong 250mg/m2(297mg)(ondy 1,8+15 everycycle),dose 5oc11,3nv11,10nv11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Fluorouracil
    Dosage: on day 1 -4,last dose on 26sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23
    End date: 2011-09-26



Possible Fluorouracil side effects in

Reported by a individual with unspecified qualification from Japan on 2012-08-06

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: df
    Indication: Oesophageal Carcinoma

Fluorouracil
    Dosage: df
    Indication: Neoplasm Malignant

Nedaplatin (Nedaplatin)
    Dosage: df
    Indication: Oesophageal Carcinoma

Therapeutic Radiopharmaceuticals (Therapeutic Radiopharmeuticals)
    Dosage: 10 mv x-rays, 2 gy daily
    Indication: Oesophageal Carcinoma

Other drugs received by patient: I.V Solutions; Fludeoxyglucose (18f)



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-31

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: (400mg/m2 intravenous bolus), (2400mg/m2)
    Indication: Colorectal Cancer

Irinotecan HCL
    Dosage: (180 mg/m2 intravenous (not otherwise specified)
    Indication: Colorectal Cancer

Levoleucovorin Calcium
    Dosage: (200 mg/m2 intravenous (not otherwise specified)
    Indication: Colorectal Cancer

Other drugs received by patient: Dexamethasone; Ondansetron Hydrochloride; Granisetron



Possible Fluorouracil side effects in 69 year old male

Reported by a physician from Japan on 2012-07-30

Patient: 69 year old male, weighing 62.0 kg (136.4 pounds)

Reactions: Paronychia, Blood Bilirubin Increased, Abdominal Pain, Pruritus, Hepatic Failure, Pyrexia, Constipation, Disease Progression, Cholangitis, Onychoclasis, Thrombocytopenia, Colorectal Cancer, Dermatitis Acneiform, Colitis Ischaemic, Stomatitis, Nausea, Haemoglobin Decreased, Diarrhoea, Neutropenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 3500 mg/body/d1-2 (1087 mg/m2/d1-2)
    Start date: 2011-03-11
    End date: 2011-03-11

Fluorouracil
    Dosage: 3500 mg/body/d1-2 (1087 mg/m2/d1-2)
    Start date: 2011-07-07
    End date: 2011-07-07

Fluorouracil
    Dosage: 3500 mg/body/d1-2 (1087 mg/m2/d1-2)
    Start date: 2011-04-08
    End date: 2011-04-08

Fluorouracil
    Dosage: 3500 mg/body/d1-2 (1087 mg/m2/d1-2)
    Start date: 2011-05-06
    End date: 2011-05-06

Fluorouracil
    Dosage: 3500 mg/body/d1-2 (1087 mg/m2/d1-2)
    Start date: 2011-06-02
    End date: 2011-06-02

Fluorouracil
    Dosage: 625 mg/body (388.2 mg/m2), 1x/day
    Start date: 2011-07-07
    End date: 2011-07-07

Fluorouracil
    Dosage: 625 mg/body (388.2 mg/m2), 1x/day
    Start date: 2011-06-02
    End date: 2011-06-02

Fluorouracil
    Dosage: 625 mg/body (388.2 mg/m2), 1x/day
    Indication: Colorectal Cancer
    Start date: 2011-03-11
    End date: 2011-03-11

Fluorouracil
    Dosage: 625 mg/body (388.2 mg/m2), 1x/day
    Start date: 2011-04-08
    End date: 2011-04-08

Fluorouracil
    Dosage: 625 mg/body (388.2 mg/m2), 1x/day
    Start date: 2011-05-06
    End date: 2011-05-06

Irinotecan Hydrochloride
    Dosage: 240 mg/body (149.1 mg/m2), 1x/day
    Start date: 2011-06-02
    End date: 2011-06-02

Irinotecan Hydrochloride
    Dosage: 240 mg/body (149.1 mg/m2), 1x/day
    Start date: 2011-04-08
    End date: 2011-04-08

Irinotecan Hydrochloride
    Dosage: 240 mg/body (149.1 mg/m2), 1x/day
    Start date: 2011-05-06
    End date: 2011-05-06

Irinotecan Hydrochloride
    Dosage: 240 mg/body (149.1 mg/m2), 1x/day
    Start date: 2011-07-07
    End date: 2011-07-07

Irinotecan Hydrochloride
    Dosage: 240 mg/body (149.1 mg/m2), 1x/day
    Indication: Colorectal Cancer
    Start date: 2011-03-11
    End date: 2011-03-11

Other drugs received by patient: Cefoperazone Sodium / Sulbactam Sodium; Seishoku; Soldem 1; Flomax; Vitamedin Intravenous; Cefdinir; Cefdinir; Loperamide Hydrochloride; Amino Acids NOS / Carbohydrates NOS / Electrolytes NOS; Levofolinate Calcium; Ascorbic Acid; Vectibix; Potassium Chloride; Metilon



Possible Fluorouracil side effects in female

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-07-27

Patient: female, weighing 67.7 kg (148.9 pounds)

Reactions: Febrile Neutropenia, Neutropenia, Bronchitis, Thrombocytopenia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cyclophosphamide
    Start date: 2012-05-24

Cyclophosphamide
    Start date: 2012-04-12

Epirubicin Hydrochloride
    Start date: 2012-05-24

Epirubicin Hydrochloride
    Start date: 2012-04-12

Fluorouracil
    Start date: 2012-04-12

Fluorouracil
    Start date: 2012-05-24

Other drugs received by patient: Nobiten; Pantoprazole; Simvastatine EG; Escitalopram Oxalate



Possible Fluorouracil side effects in 73 year old male

Reported by a health professional (non-physician/pharmacist) from Italy on 2012-07-19

Patient: 73 year old male

Reactions: Dysphagia, Blood Culture Positive, Neutropenia, Klebsiella Test Positive, Septic Shock, Thrombocytopenia, Blood Creatinine Increased, Oral Fungal Infection, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Cisplatin
    Dosage: 130 mg, total, intravenous drip
    Indication: Chemotherapy
    Start date: 2012-03-30
    End date: 2012-03-30

Docetaxel
    Dosage: 130 mg total, intravenous
    Indication: Chemotherapy
    Start date: 2012-03-30
    End date: 2012-03-30

Fluorouracil
    Dosage: 1580 mg/day, 6900 mg total
    Indication: Chemotherapy
    Start date: 2012-03-30
    End date: 2012-04-04

Other drugs received by patient: Aloxi; Trimeton; Dexamethasone; Zantac



Possible Fluorouracil side effects in 50 year old female

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-16

Patient: 50 year old female

Reactions: Diarrhoea, Neutropenia, Thrombocytopenia, Decreased Appetite, Leukopenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: 70 mg/m2 (every cycle), (reduced by 20%)
    Indication: Oesophageal Carcinoma

Docetaxel
    Dosage: 70 mg/m2, (every cycle), (reduced by 20%)
    Indication: Oesophageal Carcinoma

Fluorouracil
    Dosage: 1700 mg/m3, (reduced by 20%)
    Indication: Oesophageal Carcinoma



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-12

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: (12 mg/m2)
    Indication: Oesophageal Carcinoma

Docetaxel
    Dosage: (50 mg/m2)
    Indication: Oesophageal Carcinoma

Fluorouracil
    Dosage: (500 mg/m2)
    Indication: Oesophageal Carcinoma



Possible Fluorouracil side effects in 43 year old female

Reported by a consumer/non-health professional from United States on 2012-07-11

Patient: 43 year old female, weighing 33.0 kg (72.6 pounds)

Reactions: Pneumonia, Respiratory Failure, Neutropenia, Septic Shock, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: day 1 every cycle,last dose on 23sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23
    End date: 2011-09-23

Erbitux
    Dosage: 23sp11=1d(d1ofcycle1only),30sp11-ong 250mg/m2(297mg)(ondy 1,8+15 everycycle),dose 5oc11,3nv11,10nv11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Fluorouracil
    Dosage: on day 1 -4,last dose on 26sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23
    End date: 2011-09-26



Possible Fluorouracil side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-07-10

Patient: 64 year old male

Reactions: Portal Hypertension, Myelodysplastic Syndrome, Bone Marrow Failure, Thrombocytopenia, Post Procedural Haemorrhage

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Fluorouracil
    Dosage: the patient received 3 cycles.

Fluorouracil
    Dosage: the patient received 6 cycles over a 2 month period

Fluorouracil
    Dosage: the patient received 9 cycles

Irinotecan HCL
    Dosage: the patient received 6 cycles over a 2 month period

Oxaliplatin
    Dosage: the patient received 9 cycles

Oxaliplatin
    Dosage: the patient received 3 cycles

Oxaliplatin
    Dosage: the patient received 6 cycles over 2 month period

Other drugs received by patient: Neupogen; Therapeutic Radiopharmaceuticals



Possible Fluorouracil side effects in female

Reported by a individual with unspecified qualification from Japan on 2012-07-09

Patient: female

Reactions: Aspartate Aminotransferase Increased, Alanine Aminotransferase Increased, Thrombocytopenia, Leukopenia

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: for metastatic patients
    Indication: Breast Cancer

Cyclophosphamide
    Dosage: as adjuvant therapy

Docetaxel
    Indication: Breast Cancer

Epirubicin Hydrochloride
    Dosage: adjuvant therapy
    Indication: Breast Cancer

Fluorouracil
    Dosage: adjuvant therapy

Fluorouracil
    Dosage: adjuvant therapy
    Indication: Breast Cancer

Herceptin
    Indication: Breast Cancer

Methotrexate
    Indication: Breast Cancer

Paclitaxel

Paclitaxel
    Indication: Breast Cancer

Vinorelbine Tartrate
    Indication: Breast Cancer

Xeloda
    Indication: Breast Cancer



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-03

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: (1000 mg/m2 intra-arterial)
    Indication: Pancreatic Carcinoma non-Resectable

Gemcitabine
    Dosage: (1000 mg/m2 intravenous (not otherwise specified)
    Indication: Pancreatic Carcinoma non-Resectable



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: (425mg/m2 intravenous bolus)
    Indication: Colon Cancer

Leucovorin Calcium
    Dosage: (20mg/m2 intravenous bolus)
    Indication: Colon Cancer

Levamisole
    Dosage: 50mg
    Indication: Colon Cancer



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from France on 2012-07-02

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Cetuximab (Cetuximab)
    Dosage: see image
    Indication: Colorectal Cancer Metastatic

Fluorouracil
    Dosage: (400 mg/m2 (once) intravenous bolus), (2400 mg/m2 (every other week))
    Indication: Colorectal Cancer

Irinotecan HCL
    Dosage: (180 mg/m2 (every other week) intravenous (not otherwise specified))
    Indication: Colorectal Cancer Metastatic

Leucovorin Calcium
    Dosage: (200 mg/m2 (every other week) intravenous (not otherwise specified))
    Indication: Colorectal Cancer Metastatic

Oxaliplatin
    Dosage: (85 mg/m2 (every other week) intravenous (not otherwise specified))
    Indication: Colorectal Cancer Metastatic

Other drugs received by patient: Antihistamines; Neupogen



Possible Fluorouracil side effects in 55 year old female

Reported by a consumer/non-health professional from Japan on 2012-07-02

Patient: 55 year old female

Reactions: Neurotoxicity, Haemorrhagic Diathesis, Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Indication: Colon Cancer Stage III

Leucovorin Calcium
    Indication: Colon Cancer Stage III

Oxaliplatin
    Indication: Colon Cancer Stage III



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-29

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: 450 mg/m2, weekly, intravenous bolus
    Indication: Colorectal Cancer

Gemcitabine
    Dosage: 900 mg/m2, weekly, intravenous
    Indication: Colorectal Cancer

Leucovorin Calcium
    Dosage: 100 mg/m2, weekly, intravenous bolus
    Indication: Colorectal Cancer



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-29

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Bevacizumab
    Dosage: 5 mg/kg, weekly intravenous bolus
    Indication: Colorectal Cancer

Fluorouracil
    Dosage: 450 mg/m2, weeklu, intravenous bolus
    Indication: Colorectal Cancer

Gemcitabine
    Dosage: 900 mg/m2, weekly, intravenous
    Indication: Colorectal Cancer

Leucovorin Calcium
    Dosage: 100 mg/m2, weekly, intravenous
    Indication: Colorectal Cancer



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from Taiwan, Province of China on 2012-06-26

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Cisplatin
    Dosage: (80-100 mg/m2 bolus infusion)
    Indication: Head and Neck Cancer

Fluorouracil
    Dosage: (800-1000 mg/m2)
    Indication: Head and Neck Cancer



Possible Fluorouracil side effects in 51 year old male

Reported by a physician from Romania on 2012-06-22

Patient: 51 year old male, weighing 76.0 kg (167.2 pounds)

Reactions: General Physical Condition Abnormal, Dehydration, Hypotension, Neutropenia, Thrombocytopenia, Leukopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Fluorouracil
    Indication: Chemotherapy
    Start date: 2012-04-06
    End date: 2012-04-10

Neulasta
    Indication: Prophylaxis
    Start date: 2012-04-12

Taxotere
    Indication: Chemotherapy
    Start date: 2012-04-09
    End date: 2012-04-09

Other drugs received by patient: Hydroxyurea



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from China on 2012-06-22

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: (2400 mg/m2 intra-arterial)
    Indication: Colorectal Cancer Stage II

Leucovorin Calcium
    Dosage: (200 mg/m2 intra-arterial)
    Indication: Colorectal Cancer Stage II

Oxaliplatin
    Dosage: (85 mg/m2 (every cycle) intra-arterial)
    Indication: Colorectal Cancer Stage II

Other drugs received by patient: Dexamethasone; Granisetron



Possible Fluorouracil side effects in 49 year old female

Reported by a physician from Lithuania on 2012-06-21

Patient: 49 year old female

Reactions: Off Label Use, Incorrect Route of Drug Administration, Drug Effect Decreased, Thrombocytopenia, Transaminases Increased

Drug(s) suspected as cause:
Alfa Interferon
    Dosage: 4 mu/m2 day 1-3 with a 40-50 days interval
    Indication: Metastases To Liver

Alfa Interferon
    Dosage: 4 mu/m2 day 1-3 with a 40-50 days interval
    Indication: Renal Mass

Alfa Interferon
    Dosage: 4 mu/m2 day 1-3 with a 40-50 days interval
    Indication: Iritic Melanoma

Cisplatin
    Dosage: day 1
    Indication: Iritic Melanoma

Cisplatin
    Dosage: day 1
    Indication: Renal Mass

Cisplatin
    Dosage: day 1
    Indication: Metastases To Liver

Doxorubicin HCL
    Dosage: day 1
    Indication: Metastases To Liver

Doxorubicin HCL
    Dosage: day 1
    Indication: Iritic Melanoma

Doxorubicin HCL
    Dosage: day 1
    Indication: Renal Mass

Fluorouracil
    Dosage: day 1-3
    Indication: Renal Mass

Fluorouracil
    Dosage: day 1-3
    Indication: Iritic Melanoma

Fluorouracil
    Dosage: day 1-3
    Indication: Metastases To Liver



Possible Fluorouracil side effects in

Reported by a health professional (non-physician/pharmacist) from China on 2012-06-21

Patient:

Reactions: Thrombocytopenia

Drug(s) suspected as cause:
Fluorouracil
    Dosage: (2400 mg/m2 intra-arterial)
    Indication: Colorectal Cancer Stage III

Leucovorin Calcium
    Dosage: (200 mg/m2 intra-arterial)
    Indication: Colorectal Cancer Stage III

Oxaliplatin
    Dosage: (85 mg/m2 (every cycle) intra-arterial)
    Indication: Colorectal Cancer Stage III

Other drugs received by patient: Granisetron; Dexamethasone Sodium Phosphate



Possible Fluorouracil side effects in male

Reported by a health professional (non-physician/pharmacist) from France on 2012-06-20

Patient: male, weighing 72.0 kg (158.4 pounds)

Reactions: Coma, Microcytic Anaemia, Anaemia Macrocytic, Multi-Organ Failure, Coombs Positive Haemolytic Anaemia, Aplasia Pure RED Cell, Thrombocytopenia, Shock

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Eloxatin
    Dosage: 25 mg/m2 for 4 days,every 15 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2007-05-05
    End date: 2007-08-01

Eloxatin
    Dosage: 25 mg/m2 for 4 days,every 15 days
    Start date: 2008-01-21
    End date: 2008-01-01

Eloxatin
    Dosage: 20 mg/m2; frequency unspecified
    Start date: 2008-03-20
    End date: 2008-10-09

Emend
    Dosage: unspecified dose for 4 days,every 15 days
    Indication: Prophylaxis of Nausea and Vomiting
    Start date: 2008-09-04
    End date: 2008-10-09

Erbitux
    Dosage: 500 mg/m2 for 4 days,every 15 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2007-08-01
    End date: 2007-01-01

Erbitux
    Dosage: 500 mg/m2 for 4 days,every 15 days
    Start date: 2008-01-21
    End date: 2008-01-01

Erbitux
    Dosage: 500 mg/m2 for 4 days,every 15 days
    Start date: 2008-03-20
    End date: 2008-10-09

Fluorouracil
    Dosage: 1000 mg/m2 for 4 days,every 15 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2007-05-05
    End date: 2007-08-01

Fluorouracil
    Dosage: 1000 mg/m2 for 4 days,every 15 days
    Start date: 2008-01-21
    End date: 2008-01-01

Fluorouracil
    Dosage: 800 mg/m2 for 4 days,every 15 days
    Start date: 2008-03-20
    End date: 2008-10-09

Irinotecan HCL
    Dosage: unspecified dose for 4 days,every 15 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2008-09-04
    End date: 2008-10-09

Levoleucovorin Calcium
    Dosage: 300 mg/m2 for 4 days,every 15 days
    Start date: 2008-03-20
    End date: 2008-10-09

Levoleucovorin Calcium
    Dosage: 400 mg/m2 for 4 days,every 15 days
    Indication: Colorectal Cancer Metastatic
    Start date: 2007-05-05
    End date: 2007-08-01

Levoleucovorin Calcium
    Dosage: 400 mg/m2 for 4 days,every 15 days
    Start date: 2008-01-21
    End date: 2008-01-01



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