Erbitux (Cetuximab) - Death - Suspected Cause - Side Effect Reports

Possible Erbitux side effects in 76 year old male

Reported by a consumer/non-health professional from Japan on 2012-08-07

Patient: 76 year old male, weighing 57.0 kg (125.4 pounds)

Reactions: Lung Disorder, Skin Disorder

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Irinotecan HCL
    Indication: Colorectal Cancer Recurrent

Erbitux
    Dosage: 250mg/m2:unk 300mg/m2:jan12-25jan12
    Indication: Colorectal Cancer Recurrent
    Start date: 2011-01-01
    End date: 2012-01-25

Other drugs received by patient: Fluorouracil; Restamin; Maglax; Rabeprazole Sodium; Furosemide; Acecol; Pursennid; Claritin; Pravastatin; Leucovorin Calcium; Mucosta; Depas; Dexamethasone Sodium Phosphate

Possible Erbitux side effects in male

Reported by a physician from France on 2012-08-06

Patient: male

Reactions: Disease Progression, Epistaxis

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux
    Start date: 2010-06-15
    End date: 2010-09-08

Avastin
    Indication: Colon Cancer
    Start date: 2009-07-23
    End date: 2010-06-02

Vectibix
    Start date: 2010-11-23
    End date: 2010-12-17

Other drugs received by patient: Fluorouracil; Leucovorin Calcium; Oxaliplatin; Irinotecan HCL; Fluorouracil; Leucovorin Calcium; Irinotecan Hydrochloride

Possible Erbitux side effects in 76 year old male

Reported by a consumer/non-health professional from Germany on 2012-07-30

Patient: 76 year old male, weighing 57.0 kg (125.4 pounds)

Reactions: Lung Disorder, Skin Disorder

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Irinotecan HCL
    Indication: Colorectal Cancer Recurrent

Erbitux
    Dosage: 250mg/m2:unk 300mg/m2:jan12-stopped
    Indication: Colorectal Cancer Recurrent
    Start date: 2011-01-01

Other drugs received by patient: Maglax; Claritin; Acecol; Dexamethasone Sodium Phosphate; Pursennid; Pravastatin; Leucovorin Calcium; Mucosta; Restamin; Furosemide; Depas; Rabeprazole Sodium; Fluorouracil

Possible Erbitux side effects in 81 year old male

Reported by a consumer/non-health professional from United States on 2012-07-24

Patient: 81 year old male, weighing 91.0 kg (200.2 pounds)

Reactions: Head Injury, Fall

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux

Possible Erbitux side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-24

Patient: 64 year old male, weighing 111.0 kg (244.2 pounds)

Reactions: Dermatitis Acneiform, Weight Decreased, Dyspnoea, Dysphonia, Recall Phenomenon, Pneumonia Staphylococcal, Myocardial Infarction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Taxotere
    Dosage: total dose: 32 mg,last administered:30oct2006
    Indication: Head and Neck Cancer
    Start date: 2006-10-30
    End date: 2006-10-30

Erbitux
    Dosage: arm 1:400mg/m2,iv:120 min,day 1,other chemo/radiation that day/week.last adminstered:30oct06,540mg
    Indication: Head and Neck Cancer
    Start date: 2006-10-30
    End date: 2006-10-30

Possible Erbitux side effects in 71 year old male

Reported by a consumer/non-health professional from Germany on 2012-07-24

Patient: 71 year old male, weighing 72.0 kg (158.4 pounds)

Reactions: Dyspnoea, Sepsis, Pyrexia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux

Other drugs received by patient: Leucovorin Calcium; Ondansetron; Fluorouracil; Oxaliplatin

Possible Erbitux side effects in 55 year old male

Reported by a consumer/non-health professional from United States on 2012-07-13

Patient: 55 year old male

Reactions: Death, Back Pain, Dysphagia, Dehydration, Cough

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux
    Indication: Head and Neck Cancer

Erbitux
    Indication: Hepatic Neoplasm Malignant

Other drugs received by patient: Methadone HCL; Ibuprofen; Vicodin

Possible Erbitux side effects in 43 year old female

Reported by a consumer/non-health professional from United States on 2012-07-11

Patient: 43 year old female, weighing 33.0 kg (72.6 pounds)

Reactions: Pneumonia, Respiratory Failure, Neutropenia, Septic Shock, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux
    Dosage: 23sp11=1d(d1ofcycle1only),30sp11-ong 250mg/m2(297mg)(ondy 1,8+15 everycycle),dose 5oc11,3nv11,10nv11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Cisplatin
    Dosage: day 1 every cycle,last dose on 23sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23
    End date: 2011-09-23

Fluorouracil
    Dosage: on day 1 -4,last dose on 26sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23
    End date: 2011-09-26

Possible Erbitux side effects in 45 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-07-06

Patient: 45 year old male, weighing 75.0 kg (165.0 pounds)

Reactions: Diarrhoea, Ileus

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux

Other drugs received by patient: Antihistamine Drugs; Corticosteroid; Pantoprazole; Fluorouracil; Irinotecan HCL; Leucovorin Calcium; Oxaliplatin; Hydromorphone HCL; Acetaminophen

Possible Erbitux side effects in 46 year old male

Reported by a consumer/non-health professional from France on 2012-07-03

Patient: 46 year old male

Reactions: Death, Dyspnoea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Morphine Sulfate
    Dosage: also received 30mg
    Administration route: Oral
    Indication: Cancer Pain
    Start date: 2012-01-01
    End date: 2012-05-05

Fluorouracil
    Dosage: no of course:2
    Start date: 2012-05-05

Cisplatin
    Dosage: no of course:2
    Start date: 2012-05-05

Erbitux
    Dosage: no of course:2
    Start date: 2012-05-05

Oramorph SR
    Dosage: 1 df = 40 to 60 mg,also received 260mg,20mg
    Administration route: Oral
    Indication: Cancer Pain

Methadone HCL
    Dosage: methadone ap-hp,also received 40mg
    Administration route: Oral
    Indication: Cancer Pain
    Start date: 2012-05-06

Possible Erbitux side effects in

Reported by a consumer/non-health professional from Germany on 2012-06-27

Patient:

Reactions: Neutropenia, Renal Failure Acute

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux

Possible Erbitux side effects in 50 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-22

Patient: 50 year old female, weighing 46.7 kg (102.8 pounds)

Reactions: Death, Lymphopenia, Oropharyngeal Cancer Stage Unspecified, Progressive Multifocal Leukoencephalopathy

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Rituximab
    Indication: Rheumatoid Arthritis
    Start date: 2006-11-01
    End date: 2006-11-02

Prednisone TAB
    Administration route: Oral
    Start date: 2003-07-01

Rituximab
    Start date: 2004-12-01

Carboplatin
    Indication: Tonsil Cancer
    Start date: 2007-08-07
    End date: 2007-09-21

Methylprednisolone
    Start date: 2004-03-16
    End date: 2006-11-11

Prednisone TAB
    Dosage: dose unknown, days 2-14
    Administration route: Oral
    Indication: Rheumatoid Arthritis

Prednisone TAB
    Administration route: Oral
    Start date: 2003-07-01

Rituximab
    Start date: 2003-07-01

Erbitux
    Indication: Tonsil Cancer
    Start date: 2007-08-07

Methylprednisolone
    Indication: Premedication
    Start date: 2003-07-01

Remicade
    Indication: Product Used FOR Unknown Indication
    Start date: 2002-03-01

Methylprednisolone
    Start date: 2003-07-01

Prednisone TAB
    Dosage: dose unknown, days 2-14
    Administration route: Oral
    Indication: Premedication

Rituximab
    Start date: 2004-03-01

Methylprednisolone
    Indication: Rheumatoid Arthritis
    Start date: 2004-03-16
    End date: 2006-11-11

Other drugs received by patient: Nexium; Estrogen; Hydroxychloroquine Sulfate; Acyclovir; Doxycycline; Folic Acid; Ranitidine; Calcium W / Vitamin D; Lovenox; Lodine; Diflucan; Lotrisone; Levothyroxine; Vigamox; Oxycontin; Clindamycin; Decadron; Cymbalta; Methotrexate; Reglan; Darvocet; Invanz; Fluconazole; Provigil

Possible Erbitux side effects in 63 year old male

Reported by a consumer/non-health professional from United States on 2012-06-21

Patient: 63 year old male

Reactions: Pneumonia, Neoplasm Malignant

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux
    Dosage: last dose on 13mar12
    Indication: Laryngeal Cancer
    Start date: 2012-02-01
    End date: 2012-03-13

Erbitux
    Dosage: last dose on 13mar12
    Indication: Oropharyngeal Cancer Stage Unspecified
    Start date: 2012-02-01
    End date: 2012-03-13

Erbitux
    Dosage: last dose on 13mar12
    Indication: Throat Cancer
    Start date: 2012-02-01
    End date: 2012-03-13

Possible Erbitux side effects in 75 year old male

Reported by a consumer/non-health professional from Germany on 2012-06-19

Patient: 75 year old male, weighing 57.0 kg (125.4 pounds)

Reactions: Lung Disorder

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux

Other drugs received by patient: Maglax; Pravastatin; Pursennid; Mucosta; Claritin; Acecol; Furosemide; Depas; Rabeprazole Sodium

Possible Erbitux side effects in 75 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-06-19

Patient: 75 year old male, weighing 64.0 kg (140.8 pounds)

Reactions: Pneumonia, Cardiac Failure Congestive

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux
    Dosage: strength:5mg/ml recent inf(10th):15nov10
    Indication: Head and Neck Cancer
    Start date: 2010-09-06
    End date: 2010-11-15

Cisplatin
    Dosage: recent inf(4th):15nov10
    Indication: Head and Neck Cancer
    Start date: 2010-09-06
    End date: 2010-11-15

Fluorouracil
    Dosage: continuous inf from day 1 to day 4 of cycle recent inf(4th):15nov10
    Indication: Head and Neck Cancer
    Start date: 2010-09-06
    End date: 2010-11-19

Possible Erbitux side effects in 43 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-15

Patient: 43 year old female, weighing 33.0 kg (72.6 pounds)

Reactions: Pneumonia, Respiratory Failure, Neutropenia, Thrombocytopenia, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: day 1 every cycle,last dose on 23sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Erbitux
    Dosage: 23sp11=1d(d1ofcycle1only),30sp11-ong 250mg/m2(297mg)(ondy 1,8+15 everycycle),dose 5oc11,3nv11,10nv11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Fluorouracil
    Dosage: on day 1 -4,last dose on 26sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Possible Erbitux side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-10

Patient: 64 year old male, weighing 111.0 kg (244.2 pounds)

Reactions: Dermatitis Acneiform, Weight Decreased, Dyspnoea, Dysphonia, Radiation Injury, Pneumonia Staphylococcal, Myocardial Infarction

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux
    Dosage: arm 1:400mg/m2,iv:120 min,day 1,other chemo/radiation that day/week.last adminstered:30oct06,540mg
    Indication: Head and Neck Cancer
    Start date: 2006-10-30
    End date: 2006-10-30

Taxotere
    Dosage: total dose: 32 mg,last administered:30oct2006
    Indication: Head and Neck Cancer
    Start date: 2006-10-30
    End date: 2006-10-30

Possible Erbitux side effects in 43 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-07

Patient: 43 year old female, weighing 33.0 kg (72.6 pounds)

Reactions: Pneumonia, Respiratory Failure, Neutropenia, Thrombocytopenia, Septic Shock

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: day 1 every cycle,last dose on 23sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Fluorouracil
    Dosage: on day 1 -4,last dose on 26sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Erbitux
    Dosage: 23sp11=1d(d1ofcycle1only),30sp11-ong 250mg/m2(297mg)(ondy 1,8+15 everycycle),dose 5oc11,3nv11,10nv11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Possible Erbitux side effects in 43 year old female

Reported by a consumer/non-health professional from United States on 2012-06-06

Patient: 43 year old female, weighing 33.0 kg (72.6 pounds)

Reactions: Pneumonia, Respiratory Failure, Neutropenia, Septic Shock, Thrombocytopenia

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: day 1 every cycle,last dose on 23sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Erbitux
    Dosage: 23sep11=1d(d1ofcycle1only),30sep11-ong 250mg/m2(297mg)(on day 1,8+15 everycycle),last dose on5oct11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Fluorouracil
    Dosage: on day 1 -4,last dose on 26sep11
    Indication: Head and Neck Cancer
    Start date: 2011-09-23

Possible Erbitux side effects in 76 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-06-04

Patient: 76 year old male, weighing 71.0 kg (156.2 pounds)

Reactions: Hypotension, General Physical Health Deterioration, Hepatic Failure, Dizziness

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux

Other drugs received by patient: Capecitabine

Possible Erbitux side effects in 54 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-29

Patient: 54 year old male

Reactions: Death, Vomiting, Nausea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Carboplatin
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Lortab
    Indication: Product Used FOR Unknown Indication

Atripla
    Indication: Product Used FOR Unknown Indication

Taxol
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Fentanyl
    Indication: Product Used FOR Unknown Indication

Possible Erbitux side effects in 60 year old male

Reported by a pharmacist from United States on 2012-05-25

Patient: 60 year old male, weighing 111.0 kg (244.2 pounds)

Reactions: Agitation, Dyspnoea, Pruritus, Unresponsive To Stimuli, Cardiac Disorder, Flushing, Incoherent, Cyanosis, Ocular Hyperaemia, Pulse Absent

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux
    Dosage: 800mg once iv
    Indication: Tonsil Cancer
    Start date: 2012-05-14
    End date: 2012-05-14

Erbitux

Possible Erbitux side effects in 54 year old male

Reported by a physician from United States on 2012-05-22

Patient: 54 year old male

Reactions: Death, Vomiting, Nausea, Cough

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Lortab

Fentanyl-100

Carboplatin
    Dosage: 545 mg total
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11
    End date: 2011-01-01

Taxol
    Dosage: 269 mg total
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11
    End date: 2011-01-01

Erbitux
    Dosage: 447.5 mg total
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Atripla

Possible Erbitux side effects in male

Reported by a physician from United States on 2012-05-17

Patient: male

Reactions: Death, Malaise

Adverse event resulted in: death

Drug(s) suspected as cause:
Taxol

Zometa
    Start date: 2011-04-01

Erbitux

Possible Erbitux side effects in 76 year old female

Reported by a health professional (non-physician/pharmacist) from France on 2012-05-15

Patient: 76 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Colon Cancer Metastatic, Intracranial Tumour Haemorrhage, Central Nervous System Lesion, General Physical Health Deterioration, Somnolence, Disease Progression, Diarrhoea, Brain Oedema, Neutropenia, Escherichia Sepsis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux
    Dosage: unk
    Indication: Colon Cancer Metastatic
    Start date: 2009-04-07
    End date: 2009-05-05

Irinotecan HCL
    Dosage: unk
    Indication: Colon Cancer Metastatic
    Start date: 2008-09-10
    End date: 2009-05-05

Levoleucovorin Calcium
    Dosage: unk
    Start date: 2008-09-10
    End date: 2009-04-07

Avastin
    Dosage: 5 mg/kg
    Indication: Colon Cancer Metastatic
    Start date: 2008-09-12
    End date: 2009-03-11

Fluorouracil
    Dosage: unk
    Indication: Colon Cancer Metastatic
    Start date: 2008-09-10
    End date: 2009-05-05

Other drugs received by patient: Polaramine; Actos; Repaglinide; Zofran; Celiprolol; Solu-Medrol; Neulasta; Pravastatin; Coaprovel; Atropine

Possible Erbitux side effects in 57 year old male

Reported by a health professional (non-physician/pharmacist) from Australia on 2012-05-10

Patient: 57 year old male

Reactions: Intestinal Obstruction

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux

Possible Erbitux side effects in 80 year old male

Reported by a consumer/non-health professional from Germany on 2012-05-09

Patient: 80 year old male, weighing 47.0 kg (103.4 pounds)

Reactions: Interstitial Lung Disease, Decreased Appetite

Adverse event resulted in: death

Drug(s) suspected as cause:
Erbitux

Other drugs received by patient: Miya-BM; Loxonin; Oxinorm; Amoban; Magmitt; Amlodipine; Lansoprazole; Butylscopolamine; Oxycontin; Aitorol

Possible Erbitux side effects in 54 year old male

Reported by a consumer/non-health professional from United States on 2012-05-08

Patient: 54 year old male, weighing 66.0 kg (145.2 pounds)

Reactions: Death, Vomiting, Nausea

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Atripla

Lortab

Erbitux
    Dosage: courses:18 last dose on 22aug2011
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Fentanyl

Carboplatin
    Dosage: last dose on 08aug2011 courses:18
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Taxol
    Dosage: courses:18 last dose on 08aug2011
    Indication: non-Small Cell Lung Cancer
    Start date: 2011-04-11

Possible Erbitux side effects in 56 year old female

Reported by a consumer/non-health professional from United States on 2012-05-07

Patient: 56 year old female, weighing 105.0 kg (231.0 pounds)

Reactions: Acute Myelomonocytic Leukaemia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carboplatin
    Dosage: 1df=auc 5 on day 1 it last dose:25oct2010 2ns line trt:15nov-20dec10
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-08-23
    End date: 2010-11-08

Gemzar
    Dosage: last dose:1nov2010 4cycles
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-08-23
    End date: 2010-11-08

Erbitux
    Dosage: 250mg/m2 on day 1.day 8 + 15 from 30aug10 last dose:1nov2010(64dys) inf:9 4cycles
    Indication: non-Small Cell Lung Cancer
    Start date: 2010-08-23
    End date: 2010-11-08

Other drugs received by patient: Vicodin; Zofran; Decadron; Ativan; Docetaxel; Aloxi

Possible Erbitux side effects in 67 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-04

Patient: 67 year old male, weighing 70.0 kg (154.0 pounds)

Reactions: Cardiac Arrest, Pneumonitis

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Erbitux
    Dosage: 1st 400 mg/m2(17-jan), then 250 mg/m2 on 24-jan, 31-jan,07-feb,14-feb,21-feb and 28-feb-2006(wk 2-7)
    Indication: Head and Neck Cancer
    Start date: 2006-02-28
    End date: 2006-02-28

Cisplatin
    Dosage: 30 mg/m2 week 2 thru 7-on 24-jan, 31-jan,07-feb,14-feb,21-feb and 28-feb-2006(wk 2-7)- 30 mg/m2
    Indication: Head and Neck Cancer
    Start date: 2006-02-28
    End date: 2006-02-28

Other drugs received by patient: Vytorin; Accupril; Cardizem; Tylenol W / Codeine; Reglan; Colace; Ativan; Oxycodone HCL; Senokot