Index of reports
> Cases with Neutropenia (25)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Epirubicin where reactions include neutropenia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Epirubicin side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-08-20
Patient:
Reactions: Abdominal Pain, Vomiting, Hypersensitivity, Nausea, Skin Toxicity, Mucosal Inflammation, Fatigue, Diarrhoea, Hepatotoxicity, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Indication: Breast Cancer
Epirubicin
Indication: Breast Cancer
Fluorouracil
Indication: Breast Cancer
Herceptin
Dosage: loading dose
Indication: Breast Cancer
Herceptin
Dosage: maintenance dose
Lapatinib
Dosage: arm b
Administration route: Oral
Indication: Breast Cancer
Lapatinib
Dosage: arm c
Administration route: Oral
Paclitaxel
Indication: Breast Cancer
Possible Epirubicin side effects in 57 year old female
Reported by a consumer/non-health professional from Spain on 2012-07-27
Patient: 57 year old female
Reactions: Pyrexia, Neutropenia, Hidradenitis, Infection
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Docetaxel
Indication: Breast Cancer
Start date: 2006-08-23
End date: 2006-11-02
Epirubicin
Indication: Breast Cancer
Start date: 2006-08-23
End date: 2006-11-02
Other drugs received by patient: Hipoartel; Simvastatin; Ceftazidime; Pantoprazole
Possible Epirubicin side effects in male
Reported by a physician from Poland on 2012-07-24
Patient: male, weighing 77.0 kg (169.4 pounds)
Reactions: Dyspnoea, Pleural Effusion, Palmar-Plantar Erythrodysaesthesia Syndrome, General Physical Health Deterioration, Neutropenia, Polyneuropathy, Disease Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Capecitabine
Indication: Metastatic Gastric Cancer
Start date: 2010-10-27
End date: 2011-04-06
Epirubicin
Indication: Metastatic Gastric Cancer
Start date: 2010-10-27
End date: 2011-04-06
Oxaliplatin
Indication: Metastatic Gastric Cancer
Start date: 2010-10-27
End date: 2011-04-06
Possible Epirubicin side effects in 58 year old female
Reported by a physician from Taiwan, Province of China on 2012-07-24
Patient: 58 year old female, weighing 57.3 kg (126.1 pounds)
Reactions: Multi-Organ Failure, Pneumonia, Coagulopathy, Central Nervous System Lesion, Acute Respiratory Distress Syndrome, Neutropenia, Acute Respiratory Failure, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Epirubicin
Start date: 2010-12-28
End date: 2010-12-28
Epirubicin
Indication: Breast Cancer
Start date: 2010-09-30
End date: 2010-09-30
Taxotere
Indication: Breast Cancer
Start date: 2010-09-30
End date: 2010-09-30
Taxotere
Start date: 2010-12-28
End date: 2010-12-28
Other drugs received by patient: Granocyte
Possible Epirubicin side effects in 44 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-20
Patient: 44 year old female, weighing 55.5 kg (122.1 pounds)
Reactions: Abdominal Pain, Intestinal Ischaemia, Colitis Ischaemic, White Blood Cell Count Decreased, Vomiting, Blood Creatine Phosphokinase Increased, Gastrointestinal Necrosis, Pyrexia, Multi-Organ Failure, Diarrhoea, GAS Gangrene, Heart Rate Increased, Bone Marrow Failure, Neutropenia, Clostridial Infection
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 7 cycles, total 4 courses
Indication: Breast Cancer
Start date: 2011-07-22
End date: 2011-09-22
Epirubicin
Dosage: 7 cycles, total 4 courses
Indication: Breast Cancer
Start date: 2011-07-22
End date: 2011-09-22
Taxotere
Dosage: 4 cycles, total 3 courses, dose taken once daily
Indication: Breast Cancer
Start date: 2011-10-14
End date: 2011-11-25
Other drugs received by patient: Leucon; Lorazepam; Decadron Phosphate; Lorazepam; Kytril; Prochlorperazine; Kytril; Cepharanthin; Decadron Phosphate; Marzulene S
Possible Epirubicin side effects in 46 year old female
Reported by a health professional (non-physician/pharmacist) from Croatia (Local Name: Hrvatska) on 2012-07-20
Patient: 46 year old female, weighing 60.0 kg (132.0 pounds)
Reactions: Neutropenia, Thrombocytopenia, Leukopenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Epirubicin
Start date: 2012-05-17
End date: 2012-05-18
Epirubicin
Start date: 2012-05-17
End date: 2012-05-18
Epirubicin
Start date: 2012-05-17
End date: 2012-05-18
Ifosfamide
Start date: 2012-05-17
End date: 2012-05-18
Mesna
Start date: 2012-05-17
End date: 2012-05-18
Possible Epirubicin side effects in 58 year old female
Reported by a health professional (non-physician/pharmacist) from Hong Kong on 2012-07-20
Patient: 58 year old female
Reactions: Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: (df; every three weeks intravenous drip), (df; dose reduced intravenous drip)
Indication: Breast Cancer
Start date: 2010-08-04
End date: 2010-08-04
Epirubicin
Dosage: (df; every three weeks intravenous drip), (df; dose reduced)
Indication: Breast Cancer
Start date: 2010-08-04
End date: 2010-08-04
Fluorouracil
Dosage: (df; every three weeks intravenous drip), (df; dose reduced)
Indication: Breast Cancer
Start date: 2010-08-04
End date: 2010-08-04
Possible Epirubicin side effects in 63 year old male
Reported by a physician from Poland on 2012-06-27
Patient: 63 year old male
Reactions: Dyspnoea, Palmar-Plantar Erythrodysaesthesia Syndrome, Pleural Effusion, General Physical Health Deterioration, Neutropenia, Polyneuropathy, Disease Progression
Adverse event resulted in: death
Drug(s) suspected as cause:
Capecitabine
Indication: Product Used FOR Unknown Indication
Epirubicin
Indication: Product Used FOR Unknown Indication
Oxaliplatin
Indication: Product Used FOR Unknown Indication
Possible Epirubicin side effects in
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-25
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: (600 mg/m2 (every 3 weeks))
Indication: Breast Cancer
Docetaxel
Dosage: (100 mg/m2 (every 3 weeks))
Indication: Breast Cancer
Epirubicin
Dosage: (100 mg/m2 (every 3 weeks))
Indication: Breast Cancer
Fluorouracil
Dosage: (600 mg/m2 (every 3 weeks))
Indication: Breast Cancer
Other drugs received by patient: Filgrastim
Possible Epirubicin side effects in
Reported by a health professional (non-physician/pharmacist) from Egypt on 2012-06-15
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 500 mg/m2 (every three weeks) intravenous (not otherwise specified)
Indication: Inflammatory Carcinoma of Breast Stage III
Epirubicin
Dosage: 100 mg/m2 (every three weeks) intravenous (not otherwise specified)
Indication: Inflammatory Carcinoma of Breast Stage III
Fluorouracil
Dosage: 500 mg/m2 (every three weeks) intravenous bolus
Indication: Inflammatory Carcinoma of Breast Stage III
Possible Epirubicin side effects in 68 year old female
Reported by a physician from Japan on 2012-06-15
Patient: 68 year old female, weighing 39.9 kg (87.8 pounds)
Reactions: White Blood Cell Count Decreased, Dyspnoea, Nausea, Hypotension, Tachycardia, Toxic Epidermal Necrolysis, Pyrexia, Haemoglobin Decreased, Respiratory Failure, Circulatory Collapse, Neutropenia, Rash Vesicular, Oxygen Saturation Decreased, Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Cyclophosphamide
Indication: Breast Cancer
Start date: 2012-02-28
End date: 2012-02-28
Epirubicin
Indication: Breast Cancer
Start date: 2012-02-28
End date: 2012-02-28
Possible Epirubicin side effects in
Reported by a individual with unspecified qualification from Egypt on 2012-06-15
Patient:
Reactions: Neutropenia, Haematotoxicity
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: (500 mg/m2 (every three weeks) intravenous (not otherwise specified))
Indication: Inflammatory Carcinoma of Breast Stage III
Epirubicin
Dosage: (100 mg/m2 (every three weeks) intravenous (not otherwise specified))
Indication: Inflammatory Carcinoma of Breast Stage III
Fluorouracil
Dosage: (500 mg/m2 (every three weeks) intravenous bolus)
Indication: Inflammatory Carcinoma of Breast Stage III
Possible Epirubicin side effects in female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-06-15
Patient: female
Reactions: Alopecia, Neutropenia, Constipation
Drug(s) suspected as cause:
Cyclophosphamide
Start date: 2011-06-25
End date: 2011-09-03
Epirubicin
Start date: 2011-06-25
End date: 2011-09-03
Fluorouracil
Start date: 2011-06-25
End date: 2011-09-03
Other drugs received by patient: Levothyroxine Sodium
Possible Epirubicin side effects in 68 year old female
Reported by a physician from Japan on 2012-05-04
Patient: 68 year old female, weighing 39.9 kg (87.8 pounds)
Reactions: White Blood Cell Count Decreased, Dyspnoea, Nausea, Hypotension, Tachycardia, Toxic Epidermal Necrolysis, Pyrexia, Haemoglobin Decreased, Respiratory Failure, Circulatory Collapse, Neutropenia, Rash Vesicular, Oxygen Saturation Decreased, Shock
Adverse event resulted in: death
Drug(s) suspected as cause:
Cyclophosphamide
Indication: Breast Cancer
Start date: 2012-02-28
End date: 2012-02-28
Epirubicin
Indication: Breast Cancer
Start date: 2012-02-28
End date: 2012-02-28
Possible Epirubicin side effects in female
Reported by a health professional (non-physician/pharmacist) from Italy on 2012-03-28
Patient: female
Reactions: Alopecia, Neutropenia, Constipation
Drug(s) suspected as cause:
Epirubicin
Possible Epirubicin side effects in female
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-20
Patient: female
Reactions: Neutropenia, RIB Fracture
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: dose unit:500
Cyclophosphamide
Dosage: dose unit:200
Indication: Breast Cancer
Doxorubicin HCL
Dosage: dose unit:50
Indication: Breast Cancer
Epirubicin
Dosage: dose unit:50
Indication: Breast Cancer
Fluorouracil
Dosage: dose unit:300
Indication: Breast Cancer
Fluorouracil
Dosage: dose unit:1500
Methotrexate
Dosage: dose unit:10
Indication: Breast Cancer
Therapeutic Radiopharmaceuticals
Indication: Breast Cancer
Vincristine Sulfate
Dosage: dose unit:0.6
Indication: Breast Cancer
Possible Epirubicin side effects in 57 year old female
Reported by a physician from United States on 2012-02-27
Patient: 57 year old female, weighing 78.7 kg (173.1 pounds)
Reactions: Gastrointestinal Inflammation, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Bevacizumab
Indication: Breast Cancer
Start date: 2009-03-13
Cyclophosphamide
Indication: Breast Cancer
Start date: 2009-03-13
End date: 2009-05-12
Docetaxel
Indication: Breast Cancer
Start date: 2009-06-11
End date: 2009-06-30
Epirubicin
Indication: Breast Cancer
Start date: 2009-03-13
End date: 2009-05-12
Epirubicin
Start date: 2009-03-13
End date: 2009-05-12
Fluorouracil
Indication: Breast Cancer
Start date: 2009-03-13
End date: 2009-05-12
Other drugs received by patient: Mexaform; Esomeprazole Magnesium; Ibuprofen; Dexamethasone; Mersyndol; Dexamethasone
Possible Epirubicin side effects in 36 year old female
Reported by a health professional (non-physician/pharmacist) from China on 2012-01-23
Patient: 36 year old female
Reactions: Lymphadenopathy, Neutropenia
Drug(s) suspected as cause:
Cyclophosphamide
Indication: Breast Cancer Stage III
Docetaxel
Indication: Breast Cancer Stage III
Epirubicin
Indication: Breast Cancer Stage III
Neupogen
Indication: Neutropenia
Possible Epirubicin side effects in female
Reported by a individual with unspecified qualification from Japan on 2011-12-13
Patient: female
Reactions: Hyperventilation, Fatigue, Malaise, Neuropathy Peripheral, Neutropenia
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 500 mg/m2
Indication: Metastases To Lung
Docetaxel
Dosage: 60 mg/m2, 4 mg
Indication: Metastases To Lung
Epirubicin
Dosage: 60 mg/m2, 4 mg
Indication: Metastases To Lung
Fluorouracil
Dosage: 500 mg/m2
Indication: Metastases To Lung
Paclitaxel
Dosage: 210 mg/m2
Indication: Metastases To Lung
Possible Epirubicin side effects in 71 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-11-23
Patient: 71 year old male, weighing 75.0 kg (165.0 pounds)
Reactions: Neutropenia, Thrombocytopenia, Leukopenia, Decreased Appetite
Drug(s) suspected as cause:
Carboplatin
Dosage: 400 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Epirubicin
Dosage: 27 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Etoposide
Dosage: 70 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Fluorouracil
Dosage: 330 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Possible Epirubicin side effects in female
Reported by a physician from Germany on 2011-11-18
Patient: female
Reactions: Drug Ineffective, Neutropenia, Leukopenia
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: unk
Indication: Breast Cancer
Start date: 2011-09-06
End date: 2011-10-18
Epirubicin
Dosage: unk
Indication: Breast Cancer
Start date: 2011-09-06
End date: 2011-10-18
Fluorouracil
Dosage: unk
Indication: Breast Cancer
Start date: 2011-09-06
End date: 2011-10-18
Neulasta
Dosage: 6 mg, unk
Indication: Chemotherapy
Start date: 2011-10-19
Other drugs received by patient: Mesna; Dexamethasone; Kevatril
Possible Epirubicin side effects in female
Reported by a physician from Netherlands on 2011-11-03
Patient: female, weighing 90.4 kg (198.9 pounds)
Reactions: Urosepsis, Neutropenia, Leukopenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 1040 mg, unk
Indication: Breast Cancer
Start date: 2011-05-02
Epirubicin
Dosage: 2.08 mg, unk
Indication: Breast Cancer
Start date: 2011-05-02
Fluorouracil
Dosage: 1040 mg, unk
Indication: Breast Cancer
Start date: 2011-05-02
NO Treatment Received
Dosage: no treatment
Indication: Breast Cancer
Other drugs received by patient: Ascal; Hydrochlorothiazide; Omeprazole; Diclofenac; Ascal; Zocor; Enalapril Maleate
Possible Epirubicin side effects in 71 year old male
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-11-01
Patient: 71 year old male
Reactions: Neutropenia, Thrombocytopenia, Decreased Appetite, Leukopenia
Drug(s) suspected as cause:
Carboplatin
Dosage: 400 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Epirubicin
Dosage: 27 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Etoposide
Dosage: 70 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Fluorouracil
Dosage: 330 mg/m2, 4-week cycles, completed 6 cycles
Indication: Metastatic Gastric Cancer
Possible Epirubicin side effects in 50 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2011-10-18
Patient: 50 year old female
Reactions: Fatigue, Treatment Failure, Neutropenia
Drug(s) suspected as cause:
Cyclophosphamide
Dosage: 500 mg/m2, unk
Indication: Breast Cancer Metastatic
Docetaxel
Dosage: 60 mg/m2, unk
Indication: Breast Cancer Metastatic
Epirubicin
Dosage: 60 mg/m2, unk
Indication: Breast Cancer Metastatic
Fluorouracil
Dosage: 500 mg/m2, unk
Indication: Breast Cancer Metastatic
Possible Epirubicin side effects in female
Reported by a health professional (non-physician/pharmacist) from France on 2011-10-05
Patient: female, weighing 54.0 kg (118.8 pounds)
Reactions: Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cisplatin
Dosage: 160 mg, qd
Indication: Chemotherapy
Start date: 2011-09-01
End date: 2011-09-01
Cyclophosphamide
Dosage: 630 mg, qd
Indication: Chemotherapy
Start date: 2011-08-31
End date: 2011-09-02
Epirubicin
Dosage: 65 mg, qd
Indication: Chemotherapy
Start date: 2011-08-31
End date: 2011-08-31
Etoposide
Dosage: 160 mg, qd
Indication: Chemotherapy
Start date: 2011-08-31
End date: 2011-09-02
Neulasta
Dosage: 6 mg, one time dose
Indication: Chemotherapy
Start date: 2011-09-03
End date: 2011-09-03
Other drugs received by patient: Antineoplastic Agents
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