Index of reports
> Cases with Septic Shock (9)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Emend (Aprepitant) where reactions include septic shock. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Emend side effects in
Reported by a physician from France on 2012-08-01
Patient:
Reactions: Renal Failure, Lung Disorder, Toxic Encephalopathy, Drug Interaction, Pancytopenia, Septic Shock
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Emend
Other drugs received by patient possibly interacting with the suspect drug: Cyclophosphamide
Dosage: unk
Indication: Sarcoma
Start date: 2012-03-22
Cyclophosphamide
Dosage: unk
Start date: 2012-04-23
Cyclophosphamide
Dosage: unk
Other drugs received by patient: Calciparine; Granocyte; Zofran
Possible Emend side effects in 68 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-05-29
Patient: 68 year old female
Reactions: Intestinal Ischaemia, Dermatitis Bullous, Gastrointestinal Necrosis, Aplasia, Septic Shock, Renal Failure Acute
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Vancomycin
Start date: 2012-01-05
Zyvox
Start date: 2011-12-30
Tazobactam
Start date: 2011-12-28
End date: 2012-01-04
Hydrea
Start date: 2011-12-26
End date: 2011-12-28
Idarubicin HCL
Indication: Acute Leukaemia
Start date: 2011-12-28
End date: 2012-01-03
Valacyclovir Hydrochloride
Start date: 2011-12-28
Amiodarone HCL
Start date: 2011-12-30
Emend
Administration route: Oral
Start date: 2011-12-29
Levofloxacin
Start date: 2011-12-29
Fasturtec
Start date: 2011-12-28
Cytarabine
Indication: Acute Leukaemia
Start date: 2011-12-28
End date: 2012-01-03
Other drugs received by patient: Metoclopramide; Noxafil; Zofran; Xyzal
Possible Emend side effects in female
Reported by a physician from France on 2012-03-22
Patient: female
Reactions: Intestinal Ischaemia, Hypotension, Tachycardia, Skin Disorder, Gastrointestinal Necrosis, Lactic Acidosis, Aplasia, Multi-Organ Failure, Dehydration, Hepatocellular Injury, Dermatitis Bullous, Septic Shock, Melaena, Renal Failure Acute
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Zyvox
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-30
Valacyclovir Hydrochloride
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-28
Levofloxacin
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-29
Vancomycin
Indication: Product Used FOR Unknown Indication
Start date: 2012-01-05
Amiodarone Hydrochloride
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-30
Hydrea
Indication: Acute Leukaemia
Start date: 2011-12-26
End date: 2011-12-28
Idarubicin HCL
Indication: Acute Leukaemia
Start date: 2011-12-28
Rasburicase
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-28
Piperacillin and Tazobactam
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-28
End date: 2012-01-04
Cytarabine
Indication: Acute Leukaemia
Start date: 2011-12-28
End date: 2012-01-03
Emend
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-29
Other drugs received by patient: Metoclopramide; Noxafil; Zofran
Possible Emend side effects in 68 year old female
Reported by a consumer/non-health professional from France on 2012-03-22
Patient: 68 year old female
Reactions: Intestinal Ischaemia, Bone Marrow Failure, Dermatitis Bullous, Septic Shock, Renal Failure Acute
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Idarubicin HCL
Indication: Acute Leukaemia
Start date: 2011-12-28
Amiodarone Hydrochloride
Start date: 2011-12-30
Piperacillin and Tazobactam
Start date: 2011-12-28
End date: 2012-01-04
Levofloxacin
Start date: 2011-12-29
Fasturtec
Start date: 2011-12-28
Emend
Start date: 2011-12-29
Zyvox
Start date: 2011-12-30
Hydrea
Start date: 2011-12-26
End date: 2011-12-28
Valacyclovir Hydrochloride
Start date: 2011-12-28
Cytarabine
Indication: Acute Leukaemia
Start date: 2011-12-28
End date: 2012-01-03
Vancomycin
Start date: 2012-01-05
Possible Emend side effects in 68 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-21
Patient: 68 year old female
Reactions: Intestinal Ischaemia, Dermatitis Bullous, Aplasia, Septic Shock, Renal Failure Acute
Adverse event resulted in: death
Drug(s) suspected as cause:
Zyvox
Dosage: unk
Start date: 2011-12-30
Piperacillin and Tazobactam
Dosage: unk
Indication: Antibiotic Therapy
Start date: 2011-12-28
End date: 2012-01-04
Idarubicin HCL
Dosage: unk
Indication: Acute Leukaemia
Start date: 2011-12-28
Emend
Dosage: unk
Start date: 2011-12-29
Amiodarone HCL
Dosage: unk
Start date: 2011-12-30
Cytarabine
Dosage: 352 mg, unk
Indication: Acute Leukaemia
Start date: 2011-12-28
End date: 2012-01-03
Hydrea
Dosage: unk
Start date: 2011-12-26
End date: 2011-12-28
Levofloxacin
Dosage: unk
Start date: 2011-12-29
Vancomycin HCL
Dosage: unk
Indication: Antibiotic Therapy
Start date: 2012-01-05
Valacyclovir Hydrochloride
Dosage: unk
Start date: 2011-12-28
Fasturtec
Dosage: unk
Start date: 2011-12-28
Other drugs received by patient: Metoclopramide; Zofran; Posaconazole
Possible Emend side effects in 68 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-20
Patient: 68 year old female
Reactions: Intestinal Ischaemia, Bone Marrow Failure, Gastrointestinal Necrosis, Septic Shock, Toxic Skin Eruption, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Fasturtec
Start date: 2011-12-28
Hydrea
Start date: 2011-12-26
End date: 2011-12-28
Vancomycin
Start date: 2012-01-05
Levofloxacin
Start date: 2011-12-29
Cytarabine
Start date: 2011-12-28
Emend
Start date: 2011-12-29
Valaciclovir
Start date: 2011-12-28
Cytarabine
Piperacillin and Tazobactam
Start date: 2011-12-28
End date: 2012-01-04
Amiodarone Hydrochloride
Start date: 2011-12-30
Idarubicin HCL
Start date: 2011-12-28
Zyvox
Start date: 2011-12-30
Other drugs received by patient: Metoclopramide; Zofran; Noxafil
Possible Emend side effects in female
Reported by a physician from France on 2012-02-28
Patient: female
Reactions: Hypovolaemic Shock, Renal Failure, Encephalopathy, Tachypnoea, Urinary Retention, Lactic Acidosis, Septic Shock
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Ifosfamide
Dosage: 4160mg per day
Indication: Endometrial Sarcoma
Start date: 2011-12-05
End date: 2011-12-06
Zofran
Dosage: 8mg per day
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-05
End date: 2011-12-06
Mesna
Dosage: 1300mg three times per day
Indication: Endometrial Sarcoma
Start date: 2011-12-05
End date: 2011-12-06
Emend
Dosage: 80mg per day
Administration route: Oral
Indication: Endometrial Sarcoma
Start date: 2011-12-05
End date: 2011-12-06
Solu-Medrol
Dosage: 40mg per day
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-05
End date: 2011-12-06
Other drugs received by patient: Duragesic-100; Lyrica; Oxycodone HCL
Possible Emend side effects in 61 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-28
Patient: 61 year old female
Reactions: Renal Failure, Encephalopathy, Septic Shock
Adverse event resulted in: death, life threatening event
Drug(s) suspected as cause:
Solu-Medrol
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-05
End date: 2011-12-06
Zofran
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-05
End date: 2011-12-06
Ifosfamide
Indication: Uterine Cancer
Start date: 2011-12-05
End date: 2011-12-06
Uromitexan Baxter
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-05
End date: 2011-12-06
Emend
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-12-05
End date: 2011-12-06
Other drugs received by patient: Pregabalin; Duragesic-100; Pregabalin; Oxycodone HCL
Possible Emend side effects in 61 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-23
Patient: 61 year old female
Reactions: Urinary Tract Infection, Encephalopathy, Meningitis, Septic Shock, Renal Failure Acute
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Zofran
Dosage: 8mg/day
Start date: 2011-12-05
End date: 2011-12-06
Solu-Medrol
Dosage: 40mg/day
Indication: Chemotherapy
Start date: 2011-12-05
End date: 2011-12-06
Ifosfamide
Dosage: 4160mg/day
Indication: Chemotherapy
Start date: 2011-12-05
End date: 2011-12-06
Mesna
Dosage: 1300 mg, 3x/day
Indication: Chemotherapy
Start date: 2011-12-05
End date: 2011-12-06
Emend
Dosage: 80mg/day
Administration route: Oral
Indication: Chemotherapy
Start date: 2011-12-05
End date: 2011-12-06
Other drugs received by patient: Lyrica; Duragesic-100; Oxycodone HCL; Lyrica
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