Index of reports
> Cases with Drug Interaction (16)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Emend (Aprepitant) where reactions include drug interaction. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Emend side effects in
Reported by a physician from France on 2012-08-01
Patient:
Reactions: Renal Failure, Lung Disorder, Toxic Encephalopathy, Drug Interaction, Pancytopenia, Septic Shock
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Emend
Other drugs received by patient possibly interacting with the suspect drug: Cyclophosphamide
Dosage: unk
Indication: Sarcoma
Start date: 2012-03-22
Cyclophosphamide
Dosage: unk
Start date: 2012-04-23
Cyclophosphamide
Dosage: unk
Other drugs received by patient: Calciparine; Granocyte; Zofran
Possible Emend side effects in 45 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-06-11
Patient: 45 year old male
Reactions: Drug Interaction, Encephalopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ifosfamide
Indication: Epithelioid Sarcoma Metastatic
Start date: 2012-03-06
End date: 2012-03-08
Ifosfamide
Start date: 2012-04-05
End date: 2012-04-07
Emend
Administration route: Oral
Start date: 2012-03-06
End date: 2012-03-08
Emend
Administration route: Oral
Indication: Premedication
Start date: 2012-04-05
End date: 2012-04-07
Other drugs received by patient: Metoclopramide Hydrochloride; Metoclopramide Hydrochloride; Methylprednisolone Sodium Succinate; Mesna; Methylprednisolone Sodium Succinate
Possible Emend side effects in 65 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-04-23
Patient: 65 year old female
Reactions: Encephalopathy, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ifosfamide
Start date: 2012-02-09
End date: 2012-02-11
Emend
Administration route: Oral
Start date: 2012-02-09
End date: 2012-02-11
Other drugs received by patient: Paroxetine Hydrochloride; Ondansetron; Tenormin; Acetaminophen; Levothyroxine Sodium; Nitroderm; Mesna; Primperan TAB; Insulin; Aspirin; Oxycodone
Possible Emend side effects in 65 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2012-03-19
Patient: 65 year old female
Reactions: Encephalopathy, Drug Interaction
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ifosfamide
Start date: 2012-02-09
End date: 2012-02-11
Emend
Start date: 2012-02-09
End date: 2012-02-11
Other drugs received by patient: Oxycodone; Insulin; Ondansetron; Tenormin; Levothyroxine Sodium; Acetaminophen; Primperan TAB; Nitroderm; Aspirin; Paroxetine Hydrochloride
Possible Emend side effects in 28 year old male
Reported by a pharmacist from France on 2012-02-22
Patient: 28 year old male
Reactions: Drug Interaction, Lipase Increased, Metastases To Pancreas
Drug(s) suspected as cause:
Emend
Administration route: Oral
Start date: 2011-12-01
End date: 2011-12-02
Irinotecan HCL
Start date: 2012-02-01
Emend
Administration route: Oral
Start date: 2011-12-28
End date: 2011-12-28
Emend
Administration route: Oral
Start date: 2011-11-30
End date: 2011-11-30
Emend
Administration route: Oral
Start date: 2011-12-29
End date: 2011-12-30
Irinotecan HCL
Indication: Colorectal Cancer
Start date: 2011-08-01
End date: 2012-01-11
Emend
Administration route: Oral
Start date: 2011-12-15
End date: 2011-12-16
Emend
Administration route: Oral
Start date: 2012-01-11
End date: 2012-01-11
Emend
Administration route: Oral
Start date: 2011-12-14
End date: 2011-12-14
Other drugs received by patient: Folic Acid; Atropine; Fluorouracil
Possible Emend side effects in 28 year old male
Reported by a pharmacist from France on 2012-02-20
Patient: 28 year old male
Reactions: Drug Interaction, Lipase Increased, Metastases To Pancreas
Drug(s) suspected as cause:
Emend
Administration route: Oral
Start date: 2011-12-15
End date: 2011-12-16
Emend
Administration route: Oral
Start date: 2011-12-14
End date: 2011-12-14
Emend
Administration route: Oral
Start date: 2011-12-29
End date: 2011-12-30
Emend
Administration route: Oral
Start date: 2011-12-28
End date: 2011-12-28
Irinotecan HCL
Indication: Colorectal Cancer
Start date: 2011-08-01
End date: 2012-01-11
Emend
Administration route: Oral
Start date: 2012-01-11
End date: 2012-01-11
Emend
Administration route: Oral
Start date: 2011-11-30
End date: 2011-11-30
Irinotecan HCL
Start date: 2012-02-01
Emend
Administration route: Oral
Start date: 2011-12-01
End date: 2011-12-02
Other drugs received by patient: Fluorouracil; Folic Acid; Atropine
Possible Emend side effects in 56 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-06
Patient: 56 year old male
Reactions: Drug Interaction, Encephalopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ondansetron
Start date: 2009-08-17
End date: 2009-08-20
Ondansetron
Start date: 2009-09-07
Emend
Administration route: Oral
Indication: Prophylaxis of Nausea and Vomiting
Start date: 2009-08-17
End date: 2009-08-17
Emend
Administration route: Oral
Start date: 2009-09-07
Metoclopramide HCL
Start date: 2009-08-17
End date: 2009-08-22
Doxorubicin Hydrochloride
Indication: Teratoma
Start date: 2009-08-17
End date: 2009-08-18
Mesna
Start date: 2009-08-17
End date: 2009-08-20
Emend
Administration route: Oral
Start date: 2009-08-18
End date: 2009-08-19
Ifosfamide
Indication: Teratoma
Start date: 2009-08-17
End date: 2009-08-19
Methylprednisolone Sodium Succinate
Start date: 2009-09-07
Mesna
Start date: 2009-09-07
Ifosfamide
Start date: 2009-09-07
Doxorubicin HCL
Start date: 2009-09-07
Methylprednisolone Sodium Succinate
Start date: 2009-08-17
End date: 2009-08-20
Metoclopramide HCL
Start date: 2009-09-07
Other drugs received by patient: Tinzaparin Sodium
Possible Emend side effects in 56 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2012-02-01
Patient: 56 year old male
Reactions: Drug Interaction, Encephalopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Metoclopramide Hydrochloride
Start date: 2009-08-17
End date: 2009-08-22
Doxorubicin Hydrochloride
Indication: Teratoma
Start date: 2009-08-17
End date: 2009-08-18
Mesna
Start date: 2009-09-07
Ifosfamide
Start date: 2009-09-07
Methylprednisolone Sodium Succinate
Start date: 2009-09-07
Emend
Administration route: Oral
Start date: 2009-08-18
End date: 2009-08-19
Mesna
Start date: 2009-08-17
End date: 2009-08-20
Emend
Administration route: Oral
Start date: 2009-09-07
Ifosfamide
Indication: Teratoma
Start date: 2009-08-17
End date: 2009-08-19
Methylprednisolone Sodium Succinate
Start date: 2009-08-17
End date: 2009-08-20
Doxorubicin Hydrochloride
Start date: 2009-09-07
Metoclopramide Hydrochloride
Start date: 2009-09-07
Emend
Administration route: Oral
Indication: Prophylaxis of Nausea and Vomiting
Start date: 2009-08-17
End date: 2009-08-17
Ondansetron
Start date: 2009-08-17
End date: 2009-08-20
Ondansetron
Start date: 2009-09-07
Other drugs received by patient: Tinzaparin Sodium
Possible Emend side effects in 28 year old male
Reported by a pharmacist from France on 2012-01-27
Patient: 28 year old male
Reactions: Pancreatitis, Drug Interaction
Drug(s) suspected as cause:
Emend
Administration route: Oral
Start date: 2011-12-01
End date: 2011-12-02
Emend
Administration route: Oral
Start date: 2011-12-28
End date: 2011-12-28
Emend
Administration route: Oral
Start date: 2012-01-11
End date: 2012-01-11
Emend
Administration route: Oral
Start date: 2011-12-14
End date: 2011-12-14
Emend
Administration route: Oral
Start date: 2011-11-30
End date: 2011-11-30
Emend
Administration route: Oral
Start date: 2011-12-15
End date: 2011-12-16
Emend
Administration route: Oral
Start date: 2011-12-29
End date: 2011-12-30
Irinotecan HCL
Indication: Colorectal Cancer
Start date: 2011-08-01
End date: 2012-01-11
Other drugs received by patient: Fluorouracil; Folic Acid; Atropine
Possible Emend side effects in
Reported by a pharmacist from France on 2012-01-20
Patient:
Reactions: Drug Interaction, Epilepsy
Drug(s) suspected as cause:
Emend
Administration route: Oral
Valproic Acid
Administration route: Oral
Possible Emend side effects in 44 year old male
Reported by a physician from Netherlands on 2012-01-20
Patient: 44 year old male
Reactions: Renal Disorder, Dehydration, Drug Interaction, Inhibitory Drug Interaction, Somnolence
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Emend
Administration route: Oral
Emend
Administration route: Oral
Indication: Prophylaxis of Nausea and Vomiting
Emend
Administration route: Oral
Quetiapine Fumarate
Administration route: Oral
Indication: Anxiety
Other drugs received by patient: Dexamethasone; Ondansetron; Citalopram; Cisplatin
Possible Emend side effects in 67 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2011-12-30
Patient: 67 year old male
Reactions: Drug Interaction, Encephalopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Emend
Administration route: Oral
Indication: Prophylaxis of Nausea and Vomiting
Start date: 2010-07-06
End date: 2010-07-06
Ifosfamide
Indication: Neuroendocrine Tumour
Start date: 2010-07-06
End date: 2010-07-08
Emend
Administration route: Oral
Start date: 2010-07-07
End date: 2010-07-10
Other drugs received by patient: Doxorubicin Hydrochloride; Ondansetron; Metoclopramide Hydrochloride; Calcium Carbonate; Methylprednisolone Sodium Succinate; Mesna; Atenolol; Hydrochlorothiazide and Irbesartan; Insulin Aspart; Irbesartan; Repaglinide; Vitamins (Unspecified)
Possible Emend side effects in 56 year old male
Reported by a health professional (non-physician/pharmacist) from France on 2011-12-27
Patient: 56 year old male
Reactions: Drug Interaction, Encephalopathy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Emend
Administration route: Oral
Indication: Prophylaxis of Nausea and Vomiting
Start date: 2009-08-17
End date: 2009-08-17
Ifosfamide
Indication: Teratoma
Start date: 2009-08-17
End date: 2009-08-19
Methylprednisolone Sodium Succinate
Start date: 2009-08-17
End date: 2009-08-20
Ondansetron
Start date: 2009-09-07
Emend
Administration route: Oral
Start date: 2009-08-18
End date: 2009-08-19
Mesna
Start date: 2009-09-07
Mesna
Start date: 2009-08-17
End date: 2009-08-20
Emend
Administration route: Oral
Start date: 2009-09-07
Doxorubicin HCL
Start date: 2009-09-07
Ondansetron
Start date: 2009-08-17
End date: 2009-08-20
Metoclopramide HCL
Start date: 2009-09-07
Methylprednisolone Sodium Succinate
Start date: 2009-09-07
Methylprednisolone Sodium Succinate
Start date: 2009-08-17
End date: 2009-08-22
Ifosfamide
Start date: 2009-09-07
Doxorubicin HCL
Indication: Teratoma
Start date: 2009-08-17
End date: 2009-08-18
Other drugs received by patient: Tinzaparin Sodium
Possible Emend side effects in 65 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2011-12-07
Patient: 65 year old female
Reactions: Drug Interaction, Muscular Weakness, Rash, Paraesthesia, Mucosal Inflammation, Neutropenia, Asthenia, Decreased Appetite
Drug(s) suspected as cause:
Emend
Administration route: Oral
Start date: 2011-06-09
End date: 2011-06-09
Cyclophosphamide
Start date: 2011-04-28
End date: 2011-04-28
Emend
Administration route: Oral
Start date: 2011-06-10
End date: 2011-06-11
Docetaxel
Start date: 2011-04-28
End date: 2011-04-28
Docetaxel
Start date: 2011-05-19
End date: 2011-05-19
Docetaxel
Indication: Chemotherapy
Start date: 2011-06-09
End date: 2011-06-09
Cyclophosphamide
Indication: Chemotherapy
Start date: 2011-06-09
End date: 2011-06-09
Cyclophosphamide
Start date: 2011-05-19
End date: 2011-05-19
Other drugs received by patient: Primperan TAB; Zofran
Possible Emend side effects in 22 year old male
Reported by a physician from France on 2011-12-06
Patient: 22 year old male
Reactions: Toxic Encephalopathy, Drug Interaction, Convulsion
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Emend
Administration route: Oral
Indication: Prophylaxis of Nausea and Vomiting
Start date: 2010-01-11
End date: 2010-01-11
Emend
Administration route: Oral
Start date: 2010-01-12
End date: 2010-01-14
Ifosfamide
Start date: 2010-01-11
End date: 2010-01-13
Other drugs received by patient: Doxorubicin; Mesna; Aluminum Hydroxide and Magnesium Carbonate; Ondansetron; Methylprednisolone Sodium Succinate; Clozapine; Polyethylene Glycol 4000; Metoclopramide Hydrochloride; Etoposide; Vincristine Sulfate
Possible Emend side effects in 65 year old female
Reported by a health professional (non-physician/pharmacist) from France on 2011-11-25
Patient: 65 year old female
Reactions: Hepatic Neoplasm Malignant, Skin Toxicity, Drug Interaction, Neuropathy Peripheral, Tearfulness, Mucous Membrane Disorder, Decreased Appetite, Nausea, Muscular Weakness, Rash, Toxicity To Various Agents, Paraesthesia, Eye Pain, Mucosal Inflammation, Dysgeusia, Activities of Daily Living Impaired, Gait Disturbance, Neutropenia, Asthenia, Infection
Drug(s) suspected as cause:
Docetaxel
Dosage: see image
Indication: Product Used FOR Unknown Indication
Start date: 2011-06-09
Docetaxel
Dosage: see image
Indication: Product Used FOR Unknown Indication
Start date: 2011-05-19
Docetaxel
Dosage: see image
Indication: Product Used FOR Unknown Indication
Start date: 2011-04-28
Cyclophosphamide
Dosage: see image
Indication: Product Used FOR Unknown Indication
Start date: 2011-04-28
Cyclophosphamide
Dosage: see image
Indication: Product Used FOR Unknown Indication
Start date: 2011-05-19
Cyclophosphamide
Dosage: see image
Indication: Product Used FOR Unknown Indication
Start date: 2011-06-09
Emend
Dosage: 125 mg milligram(s), unknown, oral; 80 mg milligram(s) (unknown) oral
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-06-09
End date: 2011-06-09
Emend
Dosage: 125 mg milligram(s), unknown, oral; 80 mg milligram(s) (unknown) oral
Administration route: Oral
Indication: Product Used FOR Unknown Indication
Start date: 2011-06-10
End date: 2011-06-11
Other drugs received by patient: Primperan TAB; Ondansetron
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