This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Elspar (Asparaginase) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (297)
Death (42)
Life Threatening Events (4)
Reports by Reaction Type
Embolism (47),
Infection (40),
Neutropenia (37),
Osteonecrosis (34),
Convulsion (15),
Toxicity To Various Agents (14),
Pyrexia (11),
Embolism Venous (11),
Off Label Use (10),
Death (8),
Posterior Reversible Encephalopathy Syndrome (8),
Sepsis (8)
Below are a few examples of reports where side effects / adverse reactions may be related to Elspar (Asparaginase). For a complete list or a specific selection of reports, please use the links above.
Possible Elspar side effects in 8 year old female
Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-08-21
Patient: 8 year old female
Reactions: Mucoepidermoid Carcinoma
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cyclophosphamide
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Indication: Acute Lymphocytic Leukaemia
Doxorubicin HCL
Indication: Acute Lymphocytic Leukaemia
Elspar
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Indication: Acute Lymphocytic Leukaemia
Methotrexate
Methotrexate
Indication: Acute Lymphocytic Leukaemia
Prednisone TAB
Dosage: unk
Indication: Acute Lymphocytic Leukaemia
Vincristine
Indication: Acute Lymphocytic Leukaemia
Possible Elspar side effects in 72 year old male
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 72 year old male, weighing 88.0 kg (193.6 pounds)
Reactions: Poor Quality Sleep, Feeling Abnormal, Fluid Retention
Drug(s) suspected as cause:
Cytarabine
Dosage: 1df:6 drips.
Elspar
Methotrexate
Sprycel
Start date: 2011-03-01
Other drugs received by patient: Nexium; Lasix
Possible Elspar side effects in 74 year old male
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient: 74 year old male
Reactions: Blood Bilirubin Increased, Pneumonia, Atrial Fibrillation, Hepatic Enzyme Increased, Death, Enterococcal Sepsis, Fluid Retention, Cardiac Failure Congestive
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Daunorubicin HCL
Dosage: on days 1,8,15,22
Indication: Acute Lymphocytic Leukaemia
Elspar
Methotrexate
Dosage: day15
Indication: Acute Lymphocytic Leukaemia
Prednisone
Indication: Acute Lymphocytic Leukaemia
Sprycel
Indication: Acute Lymphocytic Leukaemia
Start date: 2012-05-22
Vincristine
Dosage: on days 1,8,15,22
Indication: Acute Lymphocytic Leukaemia
Possible Elspar side effects in male
Reported by a physician from United States on 2012-07-26
Patient: male, weighing 13.9 kg (30.6 pounds)
Reactions: Capillary Nail Refill Test Abnormal, Tachycardia, Anaphylactic Reaction, Hypotension, Drug Hypersensitivity, Pyrexia, Respiratory Distress
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Cytarabine
Dosage: 7200 mg
Elspar
Dosage: 3600 unit
End date: 2012-07-18
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from China on 2012-07-06
Patient:
Reactions: Leukopenia
Drug(s) suspected as cause:
Elspar
Indication: T-Cell Lymphoma
Prednisone TAB
Indication: T-Cell Lymphoma
Vincrestine (Vincristine)
Indication: T-Cell Lymphoma
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from China on 2012-07-06
Patient:
Reactions: Leukopenia
Drug(s) suspected as cause:
Elspar
Indication: T-Cell Lymphoma
Prednisone TAB
Indication: T-Cell Lymphoma
Vincristine
Indication: T-Cell Lymphoma
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Encephalopathy
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia, Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Infection
Drug(s) suspected as cause:
Dexamethasone Sodium Phosphate
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a individual with unspecified qualification from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Ill-Defined Disorder
Adverse event resulted in: death
Drug(s) suspected as cause:
Cyclophosphamide
Indication: Acute Lymphocytic Leukaemia
Cytarabine
Indication: Acute Lymphocytic Leukaemia
Dexamethasone
Indication: Acute Lymphocytic Leukaemia
Elspar
Indication: Acute Lymphocytic Leukaemia
Idarubicin HCL
Indication: Acute Lymphocytic Leukaemia
Mercaptopurine
Indication: Acute Lymphocytic Leukaemia
Prednisone TAB
Indication: Acute Lymphocytic Leukaemia
Vincristine
Indication: Acute Lymphocytic Leukaemia
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia, Infection
Adverse event resulted in: death
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Extranodal NK / T-Cell Lymphoma, Nasal Type, Bone Marrow Failure, Neutropenia, Infection
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Infection
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
Possible Elspar side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-02
Patient:
Reactions: Neutropenia
Drug(s) suspected as cause:
Dexamethasone Sodium Phosphate
Indication: T-Cell Lymphoma Stage IV
Elspar
Indication: T-Cell Lymphoma Stage IV
Etoposide
Indication: T-Cell Lymphoma Stage IV
Ifosfamide
Indication: T-Cell Lymphoma Stage IV
Methotrexate Sodium
Indication: T-Cell Lymphoma Stage IV
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