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Eloxatin (Oxaliplatin) - Hypertension - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypertension (12)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Eloxatin (Oxaliplatin) where reactions include hypertension. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Eloxatin side effects in female

Reported by a physician from United States on 2012-08-22

Patient: female, weighing 67.3 kg (148.1 pounds)

Reactions: Drug Dose Omission, Vomiting, Headache, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin
    Dosage: 664 mg

Eloxatin
    Dosage: 0 mg

Fluorouracil
    Dosage: 7392 mg

Leucovorin Calcium
    Dosage: 1408 mg

Other drugs received by patient: ...



Possible Eloxatin side effects in 73 year old female

Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-07-20

Patient: 73 year old female, weighing 75.0 kg (165.0 pounds)

Reactions: Speech Disorder, Anxiety, Neuropathy Peripheral, Visual Impairment, Respiratory Distress, Hypertension

Drug(s) suspected as cause:
Eloxatin

Other drugs received by patient: Kytril; Xeloda



Possible Eloxatin side effects in 73 year old female

Reported by a health professional (non-physician/pharmacist) from Turkey on 2012-07-19

Patient: 73 year old female, weighing 75.0 kg (165.0 pounds)

Reactions: Anxiety, Speech Disorder, Neuropathy Peripheral, Visual Impairment, Respiratory Distress, Hypertension

Drug(s) suspected as cause:
Eloxatin

Other drugs received by patient: Kytril; Xeloda



Possible Eloxatin side effects in male

Reported by a physician from United States on 2012-06-15

Patient: male

Reactions: Chest Discomfort, Peripheral Sensory Neuropathy, Hypertension, Liver Disorder

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Eloxatin

Eloxatin
    Start date: 2012-01-01
    End date: 2012-01-01

Fluorouracil

Leucovorin Calcium



Possible Eloxatin side effects in 64 year old female

Reported by a physician from United States on 2012-05-17

Patient: 64 year old female, weighing 76.2 kg (167.6 pounds)

Reactions: Flank Pain, Tachycardia, Hypotension, Hypoxia, Hypertension

Adverse event resulted in: life threatening event, hospitalization

Drug(s) suspected as cause:
Eloxatin
    Dosage: 148 mg every 3 weeks iv drip
    Start date: 2009-07-27
    End date: 2012-05-07

Eloxatin
    Start date: 2009-07-27
    End date: 2012-05-07

Other drugs received by patient: Fluorouracil; Oxaliplatin; Dextrose 5%; Leucovorin Calcium



Possible Eloxatin side effects in 63 year old female

Reported by a physician from United States on 2012-03-15

Patient: 63 year old female, weighing 74.4 kg (163.7 pounds)

Reactions: Weight Decreased, Stridor, Anaphylactic Reaction, Coma, Orthostatic Hypotension, Fall, Pallor, Malignant Hypertension, Facial Paresis, Balance Disorder, Apraxia, Eyelid Ptosis, Thrombocytopenia, Transient Ischaemic Attack, Angioedema, Dyspnoea, Anaemia, Ataxia, Cognitive Disorder, Hypoxic-Ischaemic Encephalopathy, Respiratory Failure, Ventricular Fibrillation, Neutropenia, Hypertension, Cardiac Arrest, Leukocytosis

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Avastin

Avastin
    Start date: 2011-12-14
    End date: 2011-12-14

Eloxatin
    Dosage: 85mg/m2
    Start date: 2012-01-11
    End date: 2012-01-11

Eloxatin
    Start date: 2011-11-30
    End date: 2011-11-30

Eloxatin
    Start date: 2011-12-28
    End date: 2011-12-28

Fluorouracil
    Start date: 2012-01-11

Fluorouracil
    Start date: 2011-11-30
    End date: 2011-11-30

Fluorouracil
    Start date: 2011-11-30
    End date: 2011-12-02

Fluorouracil
    Start date: 2012-01-11
    End date: 2012-01-11

Leucovorin Calcium
    Start date: 2012-01-11
    End date: 2012-01-11

Leucovorin Calcium
    Start date: 2011-11-30
    End date: 2011-11-30

Other drugs received by patient: Tylenol; Diphenhydramine HCL; Zofran; Zofran; Phenergan; Phenergan; Lisinopril; Klor-CON



Possible Eloxatin side effects in 73 year old male

Reported by a physician from France on 2012-03-09

Patient: 73 year old male

Reactions: Abdominal Pain, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Eloxatin
    Dosage: 42 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-28
    End date: 2012-01-29

Erbitux
    Dosage: 500 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-27
    End date: 2012-01-27

Fluorouracil
    Dosage: 1000 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-28

Irinotecan HCL
    Dosage: 150 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-28
    End date: 2012-01-28



Possible Eloxatin side effects in 73 year old male

Reported by a physician from France on 2012-03-02

Patient: 73 year old male

Reactions: Abdominal Pain, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Eloxatin
    Dosage: 42 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-28
    End date: 2012-01-29

Erbitux
    Dosage: 500 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-27
    End date: 2012-01-27

Fluorouracil
    Dosage: 1000 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-28
    End date: 2012-01-29

Irinotecan HCL
    Dosage: 150 mg/m2, once every 2 weeks
    Indication: Metastases To Liver
    Start date: 2012-01-28
    End date: 2012-01-28



Possible Eloxatin side effects in 63 year old female

Reported by a physician from United States on 2012-02-15

Patient: 63 year old female, weighing 74.4 kg (163.7 pounds)

Reactions: Hypersensitivity, Dyspnoea, Stridor, Pallor, Facial Paresis, Eyelid Ptosis, Ventricular Fibrillation, Cardiac Arrest, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Eloxatin
    Dosage: 85mg/m2
    Start date: 2012-01-11
    End date: 2012-01-11

Eloxatin
    Start date: 2011-11-30
    End date: 2011-11-30

Eloxatin
    Start date: 2011-12-28
    End date: 2011-12-28

Eloxatin
    Dosage: 85mg/m2
    Start date: 2012-01-11
    End date: 2012-01-11

Eloxatin
    Start date: 2011-11-30
    End date: 2011-11-30

Eloxatin
    Start date: 2011-12-28
    End date: 2011-12-28

Other drugs received by patient: Phenergan; Diphenhydramine HCL; Avastin; Acetaminophen; Avastin; Zofran; Lisinopril; Zofran; Phenergan



Possible Eloxatin side effects in 63 year old female

Reported by a physician from United States on 2012-01-31

Patient: 63 year old female

Reactions: Dyspnoea, Hypersensitivity, Stridor, Pallor, Facial Paresis, Eyelid Ptosis, Ventricular Fibrillation, Cardiac Arrest, Hypertension

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Eloxatin

Eloxatin
    Dosage: 85mg/m2
    Start date: 2012-01-12
    End date: 2012-01-12



Possible Eloxatin side effects in 81 year old female

Reported by a physician from Switzerland on 2012-01-30

Patient: 81 year old female, weighing 71.0 kg (156.2 pounds)

Reactions: Abdominal Pain, Malaise, Chest Discomfort, Type I Hypersensitivity, Rash, Hypertension

Drug(s) suspected as cause:
Aloxi
    Dosage: 0.25 mg, unk
    Start date: 2011-11-25
    End date: 2011-11-25

Clemastine Fumarate
    Dosage: 2 mg, unk
    Start date: 2011-11-25
    End date: 2011-11-25

Eloxatin
    Dosage: 100 mg, 1x/day
    Indication: Colorectal Cancer
    Start date: 2011-11-25
    End date: 2011-11-25

Solu-Medrol
    Dosage: 125 mg, unk
    Start date: 2011-11-25
    End date: 2011-11-25

Zantac
    Dosage: 50 mg, unk
    Start date: 2011-11-25
    End date: 2011-11-25

Other drugs received by patient: Vitamin D; Symbicort; Calcium; Magnesium



Possible Eloxatin side effects in 81 year old female

Reported by a physician from Switzerland on 2012-01-25

Patient: 81 year old female, weighing 71.0 kg (156.2 pounds)

Reactions: Abdominal Pain, Chest Discomfort, Malaise, Type I Hypersensitivity, Rash, Hypertension

Drug(s) suspected as cause:
Aloxi
    Dosage: .25mg per day
    Indication: Premedication
    Start date: 2011-11-25
    End date: 2011-11-25

Clemastine Fumarate
    Dosage: 2mg per day
    Indication: Premedication
    Start date: 2011-11-25
    End date: 2011-11-25

Eloxatin
    Dosage: 100mg per day
    Indication: Colorectal Cancer
    Start date: 2011-11-25
    End date: 2011-11-25

Solu-Medrol
    Dosage: 125mg per day
    Indication: Premedication
    Start date: 2011-11-25
    End date: 2011-11-25

Zantac
    Dosage: 50mg per day
    Indication: Premedication
    Start date: 2011-11-25
    End date: 2011-11-25

Other drugs received by patient: Calcium; Symbicort; Vitamin D; Magnesium Sulfate

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