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Index of reports
> Cases with Pancytopenia (9)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Doxil (Doxorubicin) where reactions include pancytopenia. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Doxil side effects in 49 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-07-06
Patient: 49 year old female
Reactions: Neoplasm Malignant, Swelling, Pancytopenia, Rash, Neurological Symptom, Generalised Oedema
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Carboplatin
Dosage: 1df=auc5 also auc4
Indication: Peritoneal Carcinoma Metastatic
Cytarabine
Indication: Peritoneal Carcinoma Metastatic
Methotrexate
Indication: Peritoneal Carcinoma Metastatic
Mitomycin
Dosage: inj
Indication: Peritoneal Carcinoma Metastatic
Cyclophosphamide
Dosage: cyclophosphamide hydrate day1 also 600mg/m2
Indication: Peritoneal Carcinoma Metastatic
Prednisolone
Indication: Peritoneal Carcinoma Metastatic
Doxil
Indication: Peritoneal Carcinoma Metastatic
Irinotecan HCL
Dosage: on day 1, 15
Indication: Peritoneal Carcinoma Metastatic
Epirubicin Hydrochloride
Dosage: day1
Indication: Peritoneal Carcinoma Metastatic
Nedaplatin
Dosage: also 60mg/m2,12mg/m2(days1-15),120mg/m2
Indication: Peritoneal Carcinoma Metastatic
Paclitaxel
Indication: Peritoneal Carcinoma Metastatic
Docetaxel
Indication: Peritoneal Carcinoma Metastatic
Possible Doxil side effects in 49 year old female
Reported by a consumer/non-health professional from Japan on 2012-06-25
Patient: 49 year old female
Reactions: Neoplasm Malignant, Swelling, Pancytopenia, Rash, Neurological Symptom, Generalised Oedema
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Mitomycin
Dosage: inj
Indication: Peritoneal Carcinoma Metastatic
Nedaplatin
Dosage: also 60mg/m2,12mg/m2(days1-15),120mg/m2
Indication: Peritoneal Carcinoma Metastatic
Irinotecan HCL
Dosage: on day 1, 15
Indication: Peritoneal Carcinoma Metastatic
Cytarabine
Indication: Peritoneal Carcinoma Metastatic
Doxil
Indication: Peritoneal Carcinoma Metastatic
Epirubicin Hydrochloride
Dosage: day1
Indication: Peritoneal Carcinoma Metastatic
Docetaxel
Indication: Peritoneal Carcinoma Metastatic
Methotrexate
Indication: Peritoneal Carcinoma Metastatic
Prednisolone
Indication: Peritoneal Carcinoma Metastatic
Carboplatin
Dosage: 1df=auc5 also auc4
Indication: Peritoneal Carcinoma Metastatic
Paclitaxel
Indication: Peritoneal Carcinoma Metastatic
Cyclophosphamide
Dosage: cyclophosphamide hydrate day1 also 600mg/m2
Indication: Peritoneal Carcinoma Metastatic
Possible Doxil side effects in 85 year old male
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-30
Patient: 85 year old male, weighing 82.1 kg (180.6 pounds)
Reactions: Diabetes Mellitus, Oral Candidiasis, Interstitial Lung Disease, Acute Respiratory Distress Syndrome, Blood Creatinine Increased, Blood Urea Increased, Vomiting, Blood Chloride Decreased, Aortic Calcification, Atrial Fibrillation, Pancytopenia, Hyponatraemia, Mitral Valve Calcification, Brain Natriuretic Peptide Increased, Pernicious Anaemia, Dehydration, Mitral Valve Incompetence, Hypothyroidism, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Revlimid
Dosage: 10 mg/daily/po
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2011-01-31
End date: 2011-02-13
Decadron
Dosage: 40 mg/wky/
Indication: Multiple Myeloma
Start date: 2011-01-31
End date: 2011-02-10
Doxil
Dosage: 8 mg
Indication: Multiple Myeloma
Start date: 2011-01-31
End date: 2011-02-10
Velcade
Dosage: 2 mg
Indication: Multiple Myeloma
Start date: 2011-01-31
End date: 2011-02-13
Other drugs received by patient: Procrit; Aspirin; Neurontin; Zometa; Ciprofloxacin; Thioctic Acid; Synthroid; Dflucan; Calcium (Unspecified); Levoxyl; Acyclovir
Possible Doxil side effects in 44 year old female
Reported by a physician from United States on 2012-04-13
Patient: 44 year old female, weighing 119.5 kg (262.9 pounds)
Reactions: White Blood Cell Count Decreased, Type 2 Diabetes Mellitus, Diabetes Mellitus, Lymphatic Disorder, Hyperglycaemia, Anaemia, Pancytopenia, Febrile Neutropenia, Cardiac Disorder, Diarrhoea, Blood Disorder, Platelet Count Decreased, Hypertension, Gastrooesophageal Reflux Disease
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Pegfilgrastim
Indication: Product Used FOR Unknown Indication
Cyclophosphamide
Indication: Breast Cancer
Start date: 2011-03-24
Doxil
Indication: Breast Cancer
Start date: 2011-03-24
Bevacizumab
Indication: Breast Cancer
Start date: 2011-03-24
Paclitaxel
Indication: Breast Cancer
Start date: 2011-03-24
Other drugs received by patient: Tylenol (Caplet); Prochlorperazine; Toprol-XL; Cefepime; Mucinex; Diflucan; Bacitracin; Ambien; Pepcid; Tessalon
Possible Doxil side effects in female
Reported by a pharmacist from Japan on 2012-04-10
Patient: female, weighing 57.0 kg (125.4 pounds)
Reactions: Hepatic Function Abnormal, Restlessness, Disseminated Intravascular Coagulation, Pancytopenia, Pyrexia, Fatigue, Malaise, Cardiac Failure, Interstitial Lung Disease, Dehydration, Bone Marrow Failure, Blood Pressure Decreased, Decreased Appetite, Anuria, Deep Vein Thrombosis
Adverse event resulted in: death, life threatening event, hospitalization
Drug(s) suspected as cause:
Doxil
Start date: 2010-11-24
End date: 2010-11-24
Doxil
Start date: 2010-11-24
End date: 2010-11-24
Doxil
Indication: Malignant Peritoneal Neoplasm
Start date: 2010-12-22
End date: 2010-12-22
Doxil
Indication: Ovarian Cancer Recurrent
Start date: 2010-12-22
End date: 2010-12-22
Cisplatin W / Docetaxel
Indication: Malignant Peritoneal Neoplasm
Cyclophosphamide
Indication: Malignant Peritoneal Neoplasm
Zosyn
Indication: Interstitial Lung Disease
Start date: 2011-01-14
End date: 2011-02-06
Minocycline Hydrochloride
Indication: Infection
Start date: 2011-01-29
End date: 2011-01-31
Minocycline Hydrochloride
Indication: Pyrexia
Start date: 2011-01-29
End date: 2011-01-31
Taxotere
Indication: Malignant Peritoneal Neoplasm
Other drugs received by patient: Methycobal; Futhan; Recomodulin; Norvasc; Elaspol; Pentamidine Isethionate; Gosha-Jinki-GAN; Bactrim; Solu-Medrol; Zithromax; Predopa; Dalteparin Sodium; Reminaron; Bactrim; Solu-Medrol; Solu-Medrol; Mucosta; DAI-Kenchu-TO; Futhan; Dalteparin Sodium; Prodif; Humulin R; Magnesium Oxide; Midazolam HCL; Midazolam HCL; Vancomycin Hydrochloride; Pentamidine Isethionate; Predopa; Vancomycin Hydrochloride; Dalteparin Sodium; Prednisolone; Concentrated Human Blood Platelets
Possible Doxil side effects in female
Reported by a physician from United States on 2012-03-23
Patient: female
Reactions: Neuropathy Peripheral, Pancytopenia
Drug(s) suspected as cause:
Revlimid
Dosage: 5 mg, 1 in 1 d, po
Administration route: Oral
Indication: Multiple Myeloma
Start date: 2010-07-19
End date: 2011-03-01
Doxil
Indication: Product Used FOR Unknown Indication
Other drugs received by patient: Fexofenadine (Fexofenadine) (Tablets); Simvastatin; Valacyclovir Hydrochloride; Seroquel; Protonix; Aspirin; Lyrica; Celebrex; Potassium Chloride; Valtrex (Valaciclovir Hydrochloride) (Tablets); Mobic
Possible Doxil side effects in female
Reported by a pharmacist from United States on 2012-01-18
Patient: female, weighing 64.4 kg (141.7 pounds)
Reactions: Asthma, Weight Decreased, Abdominal Pain, Metastases To Liver, Fungal Sepsis, Pyrexia, Chronic Obstructive Pulmonary Disease, Iron Deficiency Anaemia, Poisoning, Immunosuppression, Hydronephrosis, Hiatus Hernia, Fistula, Anaemia, Hyperglycaemia, Malnutrition, Pancytopenia, Left Ventricular Hypertrophy, Intestinal Obstruction, Malignant Neoplasm of Uterine Adnexa, Hepatic Steatosis, Cholelithiasis, Hepatic Cyst, Dehydration, Abscess, Metastases To Kidney, Neutropenia, Scar, Confusional State, Jaundice, Bone Pain, Pain, Chills, Mental Status Changes, Short-Bowel Syndrome, Constipation, Fall, Laryngitis, Hypokalaemia, Pancreatic Duct Dilatation, Fatigue, Postoperative Wound Infection, Chest Pain, Hydroureter, Pleural Effusion, Dizziness, Oedema, Electrolyte Imbalance, Depression, Decreased Appetite, Abdominal Pain Lower, Vomiting, Dyspnoea, Nausea, Urinary Tract Infection, Post Gastric Surgery Syndrome, Muscular Weakness, Anxiety, Intestinal Haemorrhage, Diarrhoea, Arthralgia, Spinal Osteoarthritis, Hypertension, Ovarian Cancer
Adverse event resulted in: death
Drug(s) suspected as cause:
Estraderm
Dosage: unk
Indication: Hormone Replacement Therapy
Start date: 1985-01-01
End date: 2003-01-01
Taxol
Carboplatin
Compazine
Topotecan
Estradiol
Dosage: unk
Indication: Hormone Replacement Therapy
Start date: 1985-01-01
End date: 2003-01-01
Doxil
Neulasta
Dosage: unk
Other drugs received by patient: Nitrofurantoin; Methylprednisolon ^jenapharm^; Ibuprofen; Metronidazol ^alpharma^; Metrogel; Cephalexin; Roxicet; Alprazolam; Dexamethasone TAB; Zithromax; Sertraline Hydrochloride; Monopril; Adipex; Robinul Forte; Enalapril Maleate; Ambien; Biaxin; Naproxen Sodium; Tamoxifen Citrate; Cefadroxil; Promethazine; Ciprofloxacin; Cyclobenzaprine; Premarin; Cleocin Hydrochloride; Dicyclomine; Temazepam; Chemotherapeutics NOS; Morphine; Fluconazole; Miralax
Possible Doxil side effects in female
Reported by a physician from United States on 2012-01-09
Patient: female, weighing 64.4 kg (141.7 pounds)
Reactions: Asthma, Abdominal Pain, Metastases To Liver, Fungal Sepsis, Pyrexia, Chronic Obstructive Pulmonary Disease, Iron Deficiency Anaemia, Poisoning, Immunosuppression, Fistula, Hiatus Hernia, Hydronephrosis, Hyperglycaemia, Anaemia, Malnutrition, Pancytopenia, Left Ventricular Hypertrophy, Malignant Neoplasm of Uterine Adnexa, Intestinal Obstruction, Hepatic Steatosis, Cholelithiasis, Hepatic Cyst, Dehydration, Neutropenia, Abscess, Metastases To Kidney, Scar, Confusional State, Pain, Chills, Bone Pain, Mental Status Changes, Short-Bowel Syndrome, Constipation, Fall, Hypokalaemia, Laryngitis, Pancreatic Duct Dilatation, Postoperative Wound Infection, Fatigue, Chest Pain, Hydroureter, Dizziness, Pleural Effusion, Oedema, Depression, Electrolyte Imbalance, Decreased Appetite, Abdominal Pain Lower, Vomiting, Dyspnoea, Nausea, Urinary Tract Infection, Post Gastric Surgery Syndrome, Muscular Weakness, Intestinal Haemorrhage, Anxiety, Arthralgia, Diarrhoea, Spinal Osteoarthritis, Hypertension, Ovarian Cancer
Adverse event resulted in: death
Drug(s) suspected as cause:
Carboplatin
Estradiol
Dosage: unk
Indication: Hormone Replacement Therapy
Start date: 1985-01-01
End date: 2003-01-01
Neulasta
Dosage: unk
Doxil
Topotecan
Estraderm
Dosage: unk
Indication: Hormone Replacement Therapy
Start date: 1985-01-01
End date: 2003-01-01
Compazine
Taxol
Other drugs received by patient: Robinul Forte; Ciprofloxacin; Zithromax; Enalapril Maleate; Metrogel; Methylprednisolon ^jenapharm^; Adipex; Alprazolam; Ibuprofen; Biaxin; Temazepam; Nitrofurantoin; Dexamethasone; Tamoxifen Citrate; Premarin; Cephalexin; Cleocin Hydrochloride; Monopril; Dicyclomine; Ambien; Fluconazole; Sertraline Hydrochloride; Cefadroxil; Chemotherapeutics NOS; Roxicet; Morphine; Metronidazol ^alpharma^; Naproxen Sodium; Cyclobenzaprine; Promethazine; Miralax
Possible Doxil side effects in female
Reported by a pharmacist from United States on 2011-11-28
Patient: female, weighing 64.4 kg (141.7 pounds)
Reactions: Asthma, Fungal Sepsis, Pyrexia, Chronic Obstructive Pulmonary Disease, Iron Deficiency Anaemia, Poisoning, Immunosuppression, Hiatus Hernia, Fistula, Hydronephrosis, Anaemia, Hyperglycaemia, Malnutrition, Left Ventricular Hypertrophy, Pancytopenia, Intestinal Obstruction, Malignant Neoplasm of Uterine Adnexa, Hepatic Steatosis, Cholelithiasis, Hepatic Cyst, Dehydration, Abscess, Neutropenia, Scar, Pain, Bone Pain, Chills, Mental Status Changes, Short-Bowel Syndrome, Constipation, Pancreatic Duct Dilatation, Hypokalaemia, Laryngitis, Postoperative Wound Infection, Fatigue, Hydroureter, Chest Pain, Oedema, Pleural Effusion, Dizziness, Depression, Electrolyte Imbalance, Decreased Appetite, Abdominal Pain Lower, Vomiting, Nausea, Urinary Tract Infection, Muscular Weakness, Intestinal Haemorrhage, Anxiety, Diarrhoea, Spinal Osteoarthritis, Hypertension, Ovarian Cancer
Adverse event resulted in: death
Drug(s) suspected as cause:
Doxil
Topotecan
Estraderm
Dosage: unk
Indication: Hormone Replacement Therapy
Start date: 1985-01-01
End date: 2003-01-01
Estradiol
Dosage: unk
Indication: Hormone Replacement Therapy
Start date: 1985-01-01
End date: 2003-01-01
Compazine
Taxol
Carboplatin
Neulasta
Dosage: unk
Other drugs received by patient: Promethazine; Nitrofurantoin; Methylprednisolon ^jenapharm^; Cefadroxil; Adipex; Enalapril Maleate; Monopril; Robinul Forte; Alprazolam; Zithromax; Dicyclomine; Dexamethasone; Tamoxifen Citrate; Biaxin; Miralax; Morphine; Ciprofloxacin; Metronidazol ^alpharma^; Sertraline Hydrochloride; Cleocin Hydrochloride; Naproxen Sodium; Ambien; Fluconazole; Cyclobenzaprine; Premarin; Cephalexin; Temazepam; Ibuprofen; Metrogel; Roxicet; Chemotherapeutics NOS
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