This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Dilantin-125 (Phenytoin) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (365)
Death (20)
Life Threatening Events (4)
Disability (1)
Reports by Reaction Type
Convulsion (108),
Stevens-Johnson Syndrome (90),
Drug Hypersensitivity (18),
Drug Ineffective (16),
Grand MAL Convulsion (16),
Headache (14),
Anticonvulsant Drug Level Decreased (14),
Rash (12),
Drug Level Decreased (10),
Malaise (9),
Toxic Epidermal Necrolysis (9),
Drug Interaction (7)
Below are a few examples of reports where side effects / adverse reactions may be related to Dilantin-125 (Phenytoin). For a complete list or a specific selection of reports, please use the links above.
Possible Dilantin-125 side effects in 62 year old male
Reported by a physician from United States on 2012-08-27
Patient: 62 year old male, weighing 93.0 kg (204.6 pounds)
Reactions: Peripheral Coldness, Back Pain, Neuropathy Peripheral, Arthritis, Intervertebral Disc Compression
Drug(s) suspected as cause:
Dilantin Kapseal
Dosage: 100 mg, 1x/day
Administration route: Oral
Indication: Convulsion
Dilantin Kapseal
Indication: Epilepsy
Dilantin-125
Dosage: 200 mg, 2x/day
Administration route: Oral
Other drugs received by patient: Enalapril Maleate; Phenobarbital TAB; Finasteride; Doxazosin Mesylate; Naproxen; Acetylsalicylic Acid
Possible Dilantin-125 side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-27
Patient: male
Reactions: Brain Neoplasm Malignant, Diabetes Mellitus, Lung Neoplasm Malignant, Blood Cholesterol Increased, Depression, Hypertension
Drug(s) suspected as cause:
Dilantin-125
Dosage: unk
Lipitor
Dosage: unk
Zoloft
Dosage: unk
Possible Dilantin-125 side effects in 82 year old female
Reported by a lawyer from United States on 2012-08-24
Patient: 82 year old female, weighing 54.0 kg (118.8 pounds)
Reactions: Blood Urea Increased, Decubitus Ulcer, Dehydration, Blood Creatinine Increased
Drug(s) suspected as cause:
Dilantin
Dosage: 100 mg, 3x/day (every 8 hours)
Start date: 2011-03-19
End date: 2011-03-24
Dilantin
Dosage: 100mg/2ml every 8 hours
Start date: 2011-03-19
Dilantin
Dosage: 750 mg, unk
Start date: 2011-03-19
Dilantin
Dosage: 100 mg, 2x/day
Administration route: Oral
Indication: Convulsion
Start date: 2011-03-13
Dilantin-125
Dosage: 125mg/ 5ml
Administration route: Oral
Indication: Convulsion
Start date: 2011-03-21
End date: 2011-03-24
Other drugs received by patient: Potassium Chloride; Norvasc; Colace; Prilosec; Aricept; Ativan; Heparin; Levaquin; Neurontin; Cozaar; Vitamin D; Cerebyx; Ferrous Sulfate
Possible Dilantin-125 side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-23
Patient: female
Reactions: Nervous System Disorder, Sensory Loss
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 9 year old male
Reported by a lawyer from United States on 2012-08-23
Patient: 9 year old male, weighing 40.0 kg (88.0 pounds)
Reactions: Stevens-Johnson Syndrome
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 63 year old male
Reported by a physician from United States on 2012-08-22
Patient: 63 year old male
Reactions: Tubulointerstitial Nephritis, Hypersensitivity, Renal Failure Acute
Drug(s) suspected as cause:
Dilantin-125
Other drugs received by patient: Lasix; Lanoxin
Possible Dilantin-125 side effects in 61 year old
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-22
Patient: 61 year old
Reactions: Drug Hypersensitivity
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 52 year old female
Reported by a physician from United States on 2012-08-21
Patient: 52 year old female
Reactions: Grand MAL Convulsion, Postictal Headache, Anticonvulsant Drug Level Increased, Toxicity To Various Agents, Fall, Loss of Consciousness, Convulsion
Drug(s) suspected as cause:
Dilantin-125
Dosage: unk
Administration route: Oral
Indication: Convulsion
Start date: 2006-01-01
Dilantin-125
Dosage: 100 mg, 2x/day
Administration route: Oral
Neurontin
Dosage: unk
Other drugs received by patient: Phenobarbital; Buspirone; Mobic
Possible Dilantin-125 side effects in 65 year old male
Reported by a consumer/non-health professional from United States on 2012-08-21
Patient: 65 year old male
Reactions: Neuropathy Peripheral, Pain in Extremity, Paraesthesia
Drug(s) suspected as cause:
Dilantin-125
Dosage: unk
Lyrica
Dosage: 50 mg, unk
Indication: Neuropathy Peripheral
Lyrica
Dosage: 200 mg, unk
Possible Dilantin-125 side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-20
Patient: female
Reactions: Tooth Disorder
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 43 year old female
Reported by a consumer/non-health professional from United States on 2012-08-17
Patient: 43 year old female, weighing 95.0 kg (209.0 pounds)
Reactions: Anticonvulsant Drug Level Decreased, Coma, Headache, Toxicity To Various Agents, Stress, Convulsion, Bronchitis, Emotional Disorder, Influenza
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin-125
Dosage: 100 mg,5x/day
Start date: 2006-01-01
End date: 2011-01-01
Klonopin
Dosage: 2 mg, 3x/day
Administration route: Oral
Indication: Convulsion
Start date: 2004-01-01
Other drugs received by patient: Bentyl; Bentyl; Benadryl; Symbicort; Acetaminophen, Aspirin, and Codeine Phosphate; Nexium; Nexium; Bentyl; Nexium; Bentyl; Promethazine Hydrochloride; Promethazine Hydrochloride; Symbicort; Bentyl
Possible Dilantin-125 side effects in 86 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-16
Patient: 86 year old female
Reactions: Drug Level Increased, Vertigo, Drug Interaction, Ataxia, Cardioactive Drug Level Increased, Prothrombin Time Prolonged, Lethargy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin-125
Other drugs received by patient possibly interacting with the suspect drug:
Amiodarone HCL
Dosage: 400 mg/day
Amiodarone HCL
Dosage: 600 mg/day
Indication: Ventricular Tachycardia
Dilantin-125
Indication: Electroencephalogram Abnormal
Other drugs received by patient: Digoxin; Furosemide; Warfarin; Potassium
Possible Dilantin-125 side effects in 46 year old female
Reported by a physician from United States on 2012-08-16
Patient: 46 year old female
Reactions: Stevens-Johnson Syndrome
Drug(s) suspected as cause:
Dilantin
Dosage: 100mg capsules two in morning and two in evening
Administration route: Oral
Indication: Grand MAL Convulsion
Start date: 2009-04-21
Dilantin
Dosage: 100mg tablets, two tablets twice daily
Administration route: Oral
Start date: 2010-01-04
End date: 2010-01-05
Dilantin-125
Dosage: 200 mg, 2x/day
Administration route: Oral
Start date: 2009-08-18
Dilantin-125
Dosage: 300 mg, 1x/day
Indication: Grand MAL Convulsion
Start date: 2009-01-01
Other drugs received by patient: Citalopram; Chlorzoxazone; Butalbital and Caffeine and Paracetamol; Meclizine; Tramadol; Lyrica; Phenergan HCL; Seroquel
Possible Dilantin-125 side effects in 70 year old
Reported by a lawyer from United States on 2012-08-14
Patient: 70 year old
Reactions: Stevens-Johnson Syndrome
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 64 year old male
Reported by a consumer/non-health professional from United States on 2012-08-14
Patient: 64 year old male
Reactions: Diabetes Mellitus, Gastric Haemorrhage
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 43 year old male
Reported by a lawyer from United States on 2012-08-14
Patient: 43 year old male
Reactions: Stevens-Johnson Syndrome
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-13
Patient: female
Reactions: Nervous System Disorder, Memory Impairment, Eye Disorder, Convulsion
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 36 year old male
Reported by a physician from United States on 2012-08-10
Patient: 36 year old male
Reactions: Lymphadenopathy, Lung Disorder, Rash Generalised, Interstitial Lung Disease, Drug Hypersensitivity, Aspartate Aminotransferase Increased, Pyrexia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 45 year old
Reported by a physician from United States on 2012-08-09
Patient: 45 year old
Reactions: Major Depression
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 43 year old female
Reported by a consumer/non-health professional from United States on 2012-08-08
Patient: 43 year old female, weighing 95.0 kg (209.0 pounds)
Reactions: Anticonvulsant Drug Level Decreased, Coma, Toxicity To Various Agents, Headache, Stress, Convulsion, Bronchitis, Emotional Disorder, Influenza
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin-125
Dosage: 100 mg,5x/day
Start date: 2006-01-01
End date: 2011-01-01
Klonopin
Dosage: 2 mg, 3x/day
Administration route: Oral
Indication: Convulsion
Start date: 2004-01-01
Other drugs received by patient: Bentyl; Promethazine Hydrochloride; Nexium; Acetaminophen, Aspirin, and Codeine Phosphate; Benadryl; Bentyl; Bentyl; Nexium; Symbicort; Symbicort; Bentyl; Promethazine Hydrochloride; Bentyl; Nexium
Possible Dilantin-125 side effects in 75 year old male
Reported by a consumer/non-health professional from United States on 2012-08-07
Patient: 75 year old male
Reactions: Therapeutic Response Unexpected, Mental Status Changes
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-06
Patient: female
Reactions: Gingivitis
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-06
Patient: female
Reactions: Tubulointerstitial Nephritis, Hypersensitivity, Hepatitis, Stevens-Johnson Syndrome
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in 79 year old female
Reported by a consumer/non-health professional from United States on 2012-08-06
Patient: 79 year old female, weighing 45.4 kg (99.8 pounds)
Reactions: Drug Ineffective, Pain, Macular Degeneration
Drug(s) suspected as cause:
Aflibercept
Dosage: unk
Indication: Macular Degeneration
Start date: 2012-07-01
Dilantin-125
Dosage: 230 mg,daily
Indication: Convulsion
Start date: 1970-01-01
Keppra
Dosage: 500 mg, 2x/day
Indication: Convulsion
Ranibizumab
Dosage: 1 mg, unk
Indication: Macular Degeneration
Start date: 2012-01-01
Other drugs received by patient: Synthroid
Possible Dilantin-125 side effects in 86 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-06
Patient: 86 year old female
Reactions: Drug Level Increased, Ataxia, Vertigo, Drug Interaction, Cardioactive Drug Level Increased, Prothrombin Time Prolonged, Lethargy
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin-125
Other drugs received by patient possibly interacting with the suspect drug:
Amiodarone HCL
Dosage: 600 mg/day
Indication: Ventricular Tachycardia
Amiodarone HCL
Dosage: 400 mg/day
Dilantin-125
Indication: Electroencephalogram Abnormal
Other drugs received by patient: Potassium; Digoxin; Furosemide; Warfarin
Possible Dilantin-125 side effects in
Reported by a consumer/non-health professional from United States on 2012-08-03
Patient:
Reactions: Road Traffic Accident
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in male
Reported by a consumer/non-health professional from United States on 2012-08-02
Patient: male
Reactions: Convulsion
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in female
Reported by a consumer/non-health professional from United States on 2012-08-02
Patient: female
Reactions: Malaise, Rash
Drug(s) suspected as cause:
Dilantin-125
Dosage: unk
Lyrica
Dosage: unk
Possible Dilantin-125 side effects in
Reported by a lawyer from United States on 2012-07-31
Patient:
Reactions: Stevens-Johnson Syndrome
Drug(s) suspected as cause:
Dilantin-125
Possible Dilantin-125 side effects in female
Reported by a lawyer from United States on 2012-07-31
Patient: female
Reactions: Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Dilantin
Dosage: 1 g, unk
Indication: Convulsion
Start date: 2011-01-12
End date: 2011-01-12
Dilantin
Dosage: 100 mg, 4x/day
Start date: 2011-01-12
End date: 2011-01-12
Dilantin
Dosage: 200 mg, 2x/day
Administration route: Oral
Start date: 2011-01-13
End date: 2011-01-13
Dilantin
Dosage: 50mg infatabs twice daily along with phenytoin 200mg capsules to make total daily dose of 500mg
Administration route: Oral
Start date: 2011-01-14
Dilantin
Dosage: 200mg capsules twice daily along with phenytoin infatabs 50mg to make total daily dose of 500mg
Administration route: Oral
Start date: 2011-01-14
Dilantin-125
Dosage: unk
Indication: Convulsion
Start date: 2010-12-01
|
