This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Didronel (Etidronate) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (20)
Death (1)
Life Threatening Events (2)
Disability (1)
Reports by Reaction Type
Femur Fracture (11),
Fall (8),
Fracture Displacement (8),
Gait Disturbance (8),
Pain in Extremity (7),
Muscular Weakness (7),
Stress Fracture (7),
Myopathy (6),
Arthralgia (6),
Pain (5),
Abdominal Discomfort (5),
Oedema Peripheral (5)
Possible Didronel side effects in
Reported by a physician from United States on 2012-08-23
Patient:
Reactions: Thrombosis, Vitamin D Deficiency, Asthma, Femur Fracture, Wrist Fracture, Eye Operation, Nephrolithiasis, Oesophageal Dilatation, Blood Cholesterol Increased, Sinusitis, RIB Fracture, Nausea, Squamous Cell Carcinoma, Urinary Tract Infection, Cystitis, Hormone Level Abnormal, Seasonal Allergy, Arthralgia, Stress Fracture, Hypertension
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fosamax Plus D
Indication: Osteoporosis
Fosamax
Dosage: 10 mg, unk
Administration route: Oral
Indication: Osteopenia
Start date: 1998-09-01
End date: 2001-10-25
Fosamax
Dosage: 70 mg, unk
Administration route: Oral
Indication: Osteoporosis
Start date: 2001-10-25
End date: 2008-07-25
Fosamax Plus D
Dosage: 70 mg, unk
Administration route: Oral
Indication: Osteopenia
Start date: 2007-06-02
End date: 2008-07-25
Alendronate Sodium
Dosage: 70 mg, unk
Administration route: Oral
Indication: Osteoporosis
Start date: 2008-07-25
End date: 2010-02-07
Didronel
Dosage: unk
Indication: Osteopenia
Start date: 1998-05-21
End date: 1998-06-20
Other drugs received by patient: Asacol; Vitamins (Unspecified); Compazine; Chlordiazepoxide; Calcium Carbonate; Corticosteroids (Unspecified); Vitamin B-12
Possible Didronel side effects in female
Reported by a physician from Finland on 2012-07-13
Patient: female
Reactions: Femur Fracture, Fracture Delayed Union, Hand Fracture
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Didronel
Administration route: Oral
Indication: Osteoporosis
Fosamax
Administration route: Oral
Indication: Osteoporosis
Boniva
Administration route: Oral
Indication: Osteoporosis
Start date: 2007-01-01
End date: 2010-01-01
Calcium
Administration route: Oral
Indication: Osteoporosis
Zoledronoc Acid
Indication: Osteoporosis
Other drugs received by patient: Medrol; Vitamin D; Calcium; Humira
Possible Didronel side effects in 38 year old female
Reported by a physician from Japan on 2012-07-11
Patient: 38 year old female
Reactions: Asthma, White Blood Cell Count Decreased, Pneumonia, Urine Output Decreased, Pseudomonas Infection, Anaemia, Iron Deficiency, Condition Aggravated, Pyrexia, Sepsis, Oedema, Acute Respiratory Distress Syndrome, Hypoalbuminaemia, Hypoxia, Neutrophil Count Decreased
Adverse event resulted in: death
Drug(s) suspected as cause:
Onon (Pranklukast)
Dosage: 180 mg, oral
Administration route: Oral
Indication: Asthma
Start date: 2010-03-01
Didronel
Dosage: 200 mg, per day, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2010-05-10
End date: 2012-01-24
Promac / 01312301 / (Polaprezinc)
Dosage: 150 mg, oral
Administration route: Oral
Indication: Zinc Deficiency
Start date: 2010-04-01
End date: 2012-04-12
Valproate Sodium
Dosage: 498 mg,qd, oral
Administration route: Oral
Indication: Epilepsy
Start date: 1974-02-01
Other drugs received by patient: Sennoside (Sennoside A+b); Intal; Glycerol 2.6%; Depas (Etizolam); ALL Other Therapeutica Products; Polmicort (Budesonide); Arderphyllin (Theophylline); Mucodyne (Carbocisteine)
Possible Didronel side effects in 61 year old female
Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-05-24
Patient: 61 year old female, weighing 57.6 kg (126.7 pounds)
Reactions: Oesophageal Squamous Cell Carcinoma, Oesophageal Stenosis
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Didronel
Possible Didronel side effects in 60 year old female
Reported by a health professional (non-physician/pharmacist) from Japan on 2012-05-17
Patient: 60 year old female, weighing 48.7 kg (107.1 pounds)
Reactions: Primary Sequestrum, Tooth Loss, Dysmorphism, Exposed Bone in JAW, Tooth Extraction, Oral Cavity Fistula, Gingival Disorder, Osteonecrosis of JAW, Impaired Healing, Breath Odour, Tenderness, Sinusitis, Pain in JAW
Drug(s) suspected as cause:
Alendronate Sodium
Dosage: 5 mg, oral
Administration route: Oral
Indication: Osteitis Deformans
Start date: 2003-03-01
End date: 2004-09-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Back Pain
Start date: 2000-11-01
End date: 2003-03-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteitis Deformans
Start date: 2000-11-01
End date: 2003-03-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Neck Pain
Start date: 2000-11-01
End date: 2003-03-01
Risedronate Sodium
Dosage: oral
Administration route: Oral
Indication: Osteitis Deformans
Start date: 2004-09-01
End date: 2005-09-01
Other drugs received by patient: Onealfa (Alfacalcidol)
Possible Didronel side effects in
Reported by a physician from Denmark on 2012-04-26
Patient:
Reactions: Primary Sequestrum, JAW Disorder, Osteomyelitis, Arteriosclerosis Coronary Artery, Acute Myocardial Infarction, Osteitis, Periostitis
Drug(s) suspected as cause:
Didronel
Possible Didronel side effects in 64 year old female
Reported by a individual with unspecified qualification from Austria on 2012-03-20
Patient: 64 year old female
Reactions: Myelofibrosis, Femur Fracture, Bone Pain, Anaphylactic Reaction, Lumbar Vertebral Fracture, Blood Parathyroid Hormone Increased, Dysstasia, Blood 25-Hydroxycholecalciferol Decreased, NO Therapeutic Response, Stress Fracture, Bone Density Decreased, Gait Disturbance, Osteocalcin Decreased, Pathological Fracture
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis
Start date: 1990-01-01
End date: 1995-01-01
Alendronate Sodium
Dosage: 70 m weekly, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 1995-01-01
End date: 2000-01-01
Alendronate Sodium
Dosage: 70 m weekly, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2000-01-01
End date: 2005-01-01
Possible Didronel side effects in
Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-02-29
Patient:
Reactions: Arteriosclerosis Coronary Artery, Acute Myocardial Infarction
Drug(s) suspected as cause:
Didronel
Possible Didronel side effects in male
Reported by a health professional (non-physician/pharmacist) from Denmark on 2012-02-21
Patient: male, weighing 74.0 kg (162.8 pounds)
Reactions: Impaired Healing, Osteonecrosis of JAW, Hypophagia, Pain in JAW
Drug(s) suspected as cause:
Zometa
Dosage: 4 mg, per 100mi nacl
Indication: Osteoporosis
Start date: 2003-10-16
Zometa
Dosage: 4 mg, per 100mi nacl
Start date: 2004-01-14
Didronel
Dosage: unk ukn, unk
Administration route: Oral
Start date: 2001-04-10
End date: 2002-06-10
Zometa
Dosage: 4 mg, per 100mi nacl
Start date: 2004-07-15
Didronel
Administration route: Oral
Indication: Osteoporosis
Start date: 2001-03-01
End date: 2002-06-01
Other drugs received by patient: Fosamax; Calciferol; Forteo; Sodium Fluoride; Fosamax; Natriumfluorid
Possible Didronel side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-17
Patient: 76 year old female
Reactions: Femur Fracture, Pain, Fall, Abdominal Discomfort, Oedema Peripheral, Fracture Displacement, Adhesion, Haematoma, LOW Turnover Osteopathy, Hyperparathyroidism Primary, Fracture Delayed Union, Muscular Weakness, Bursitis, Myopathy, Stress Fracture, Gait Disturbance, Scar
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fosamax
Dosage: 10 mgdaily, oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
Start date: 1995-12-29
End date: 2002-07-01
Actonel
Dosage: 35 mg once weekly, oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
Start date: 2002-10-30
End date: 2003-01-01
Boniva
Dosage: 150 mg once monthly, oral
Administration route: Oral
Indication: Osteopenia
Start date: 2005-12-29
End date: 2009-04-01
Boniva
Dosage: 150 mg once monthly, oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
Start date: 2005-12-29
End date: 2009-04-01
Didronel
Dosage: 200 mg twice daily times 2 weeks q 10 weeks, oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
Start date: 1993-12-21
End date: 1995-12-27
Other drugs received by patient: Acyclovir / 00587301 / (Aciclovir); Lidoderm; Arthrotec / 00372302 (Diclofenac Sodium); Cephalexin / 00145501 / (Cefalexin); Cozaar; Hydrocodone W / Apap (Hydrocodone, Paracetamol)
Possible Didronel side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-02-17
Patient: 76 year old female
Reactions: Soft Tissue Disorder, Femur Fracture, Fall, Abdominal Discomfort, Hyperparathyroidism, Oedema Peripheral, Fracture Displacement, LOW Turnover Osteopathy, Haematoma, Pain in Extremity, Fracture Delayed Union, Muscular Weakness, Bursitis, Myopathy, Stress Fracture, Gait Disturbance, Parathyroid Tumour Benign, Deep Vein Thrombosis, Scar
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Didronel
Dosage: 200 mg twice daily times two weeks cyclic every 10 weeks, oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
Start date: 1993-12-21
End date: 1995-12-29
Actonel
Dosage: 35 mg once weekly, oral
Administration route: Oral
Start date: 2002-10-30
End date: 2003-01-01
Fosamax
Dosage: 10 mg daily, oral
Administration route: Oral
Start date: 1995-12-29
End date: 2002-07-01
Boniva
Dosage: 150 mg once monthly, oral
Administration route: Oral
Start date: 2005-12-29
End date: 2009-04-01
Other drugs received by patient: Tagamet; Cytotec; Voltaren; Ranitidine Hydrochloride
Possible Didronel side effects in
Reported by a health professional (non-physician/pharmacist) from United States on 2012-01-04
Patient:
Reactions: Pancreatic Carcinoma, Hepatic Neoplasm Malignant, Oesophageal Carcinoma, Gastric Cancer
Drug(s) suspected as cause:
Didronel
Possible Didronel side effects in 76 year old female
Reported by a physician from United States on 2011-12-29
Patient: 76 year old female
Reactions: Femur Fracture, Pain, Fall, Abdominal Discomfort, Oedema Peripheral, Fracture Displacement, Haematoma, LOW Turnover Osteopathy, Anaemia Postoperative, Intervertebral Disc Operation, Hiatus Hernia, Hyperparathyroidism Primary, Pain in Extremity, Muscular Weakness, Radiotherapy, Breast Cancer Female, Bursitis, Myopathy, Osteoarthritis, Hysterectomy, Arthralgia, Stress Fracture, Parathyroid Tumour Benign, Gait Disturbance
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fosamax
Dosage: 10 mg daily, oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
Start date: 1995-12-29
End date: 2002-01-01
Actonel
Dosage: 35 mg once weekly, oral
Administration route: Oral
Indication: Osteopenia
Start date: 2002-10-30
End date: 2002-11-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis
End date: 1995-12-27
Boniva
Dosage: 150 mg once montly, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2005-12-29
End date: 2009-04-01
Other drugs received by patient: Cozaar; Arthrotec / 00372302 / (Diclofenac Sodium); Cephalexin
Possible Didronel side effects in 76 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-29
Patient: 76 year old female
Reactions: Femur Fracture, Pain, Fall, Abdominal Discomfort, Oedema Peripheral, Fracture Displacement, LOW Turnover Osteopathy, Anaemia Postoperative, Haematoma, Pain in Extremity, Hyperparathyroidism Primary, Muscular Weakness, Myopathy, Stress Fracture, Gait Disturbance, Parathyroid Tumour Benign
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fosamax
Dosage: 10 mg daily, oral
Administration route: Oral
Start date: 1995-12-29
End date: 2002-01-01
Actonel
Dosage: 35 mg once weekly, oral
Administration route: Oral
Start date: 2002-10-30
End date: 2002-11-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
End date: 1995-12-29
Boniva
Dosage: 150 ma once monthly, oral
Administration route: Oral
Start date: 2005-12-29
End date: 2009-04-01
Possible Didronel side effects in 67 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-12-07
Patient: 67 year old female
Reactions: Joint Instability, Femur Fracture, Sciatica, Bone Pain, Pain, Fall, Fracture Nonunion, Synovial Cyst, Myalgia, Fracture Displacement, Joint Effusion, Back Pain, Pain in Extremity, Device Damage, Muscular Weakness, Ankle Fracture, Myopathy, Device Failure, Impaired Healing, Arthralgia, Gait Disturbance, Muscle Disorder, Asthenia, Device Breakage
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Boniva
Dosage: 150 mg, 1 /month, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2006-01-01
End date: 2008-11-04
Actonel
Dosage: oral
Administration route: Oral
Boniva
Dosage: 150 mg, 1 /month, oral
Administration route: Oral
Indication: Osteoporosis
Fosamax
Dosage: 70 mg, 1 /week, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2004-01-01
End date: 2006-01-01
Boniva
Dosage: 150 mg, 1 /month, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2009-05-26
End date: 2010-03-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis
Alendronate Sodium
Dosage: 70 mg, 1 /week
Indication: Osteoporosis
Start date: 2008-11-04
End date: 2009-05-26
Fosamax
Dosage: 5 mg
Indication: Osteoporosis
Start date: 1998-01-01
End date: 2004-01-01
Other drugs received by patient: Avalide; Lisinopril; Toprol-XL; Aspirin; Simvastatin; Celebrex; Prozac
Possible Didronel side effects in 67 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-25
Patient: 67 year old female
Reactions: Femur Fracture, Pain in Extremity, Muscular Weakness, Fracture Nonunion, Fall, Ankle Fracture, Arthralgia, Fracture Displacement, Gait Disturbance, Device Breakage
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Fosamax
Dosage: 70 mg, 1 /week, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2004-01-01
End date: 2006-01-01
Alendronate Sodium
Dosage: 70 mg, 1 /week
Indication: Osteoporosis
Start date: 2008-11-04
End date: 2009-05-26
Boniva
Dosage: 150 mg, 1 /month, oral ; 150 mg, 1 /month, oral ; 150 mg, 1 /month, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2006-01-01
End date: 2008-11-04
Boniva
Dosage: 150 mg, 1 /month, oral ; 150 mg, 1 /month, oral ; 150 mg, 1 /month, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2009-05-26
End date: 2010-03-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis
Fosamax
Dosage: 5 mg
Indication: Osteoporosis
Start date: 1998-01-01
End date: 2004-01-01
Actonel
Dosage: oral
Administration route: Oral
Possible Didronel side effects in 67 year old female
Reported by a health professional (non-physician/pharmacist) from United States on 2011-11-25
Patient: 67 year old female
Reactions: Joint Instability, Femur Fracture, Sciatica, Fracture Nonunion, Fall, Synovial Cyst, Myalgia, Fracture Displacement, Pain in Extremity, Muscular Weakness, Ankle Fracture, Myopathy, Arthralgia, Gait Disturbance, Muscle Disorder, Asthenia, Device Breakage
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Actonel
Dosage: oral
Administration route: Oral
Fosamax
Dosage: 5 mg,
Indication: Osteoporosis
Start date: 1998-01-01
End date: 2004-01-01
Boniva
Dosage: 150 mg, 1/month, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2006-01-01
End date: 2008-11-04
Boniva
Dosage: 150 mg, 1/month, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2009-05-26
End date: 2010-03-01
Alendronate Sodium
Dosage: 70 mg, 1/week,
Indication: Osteoporosis
Start date: 2008-11-04
End date: 2009-05-26
Fosamax
Dosage: 70 mg, 1/week, oral
Administration route: Oral
Indication: Osteoporosis
Start date: 2004-01-01
End date: 2006-01-01
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis
Possible Didronel side effects in 76 year old female
Reported by a physician from United States on 2011-11-25
Patient: 76 year old female
Reactions: Femur Fracture, Pain in Extremity, Hyperparathyroidism Primary, Pain, Fall, Abdominal Discomfort, Arthralgia, Oedema Peripheral, Fracture Displacement, Stress Fracture, Haematoma, LOW Turnover Osteopathy, Anaemia Postoperative
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Didronel
Dosage: oral
Administration route: Oral
Indication: Osteoporosis Postmenopausal
End date: 1995-12-29
Actonel
Dosage: 35 mg once weekly, oral
Administration route: Oral
Start date: 2002-10-30
End date: 2002-11-01
Fosamax
Dosage: 10 mg daily, oral
Administration route: Oral
Start date: 1995-12-29
End date: 2002-01-01
Boniva
Dosage: 150 mg once monthly, oral
Administration route: Oral
Start date: 2005-12-29
End date: 2009-04-01
Possible Didronel side effects in male
Reported by a consumer/non-health professional from Denmark on 2011-11-07
Patient: male, weighing 74.0 kg (162.8 pounds)
Reactions: Impaired Healing, Osteonecrosis of JAW, Hypophagia, Pain in JAW
Drug(s) suspected as cause:
Zometa
Dosage: 4 mg, per 100mi nacl
Indication: Osteoporosis
Start date: 2003-10-16
Didronel
Administration route: Oral
Start date: 2001-03-01
End date: 2002-06-01
Zometa
Dosage: 4 mg, per 100mi nacl
Start date: 2004-07-15
Zometa
Dosage: 4 mg, per 100mi nacl
Start date: 2004-01-14
Other drugs received by patient: Calciferol; Sodium Fluoride; Fosamax; Forteo
Possible Didronel side effects in 61 year old female
Reported by a physician from United Kingdom on 2011-10-07
Patient: 61 year old female, weighing 5706.0 kg (12553.2 pounds)
Reactions: Dysphagia, Oesophageal Squamous Cell Carcinoma
Adverse event resulted in: life threatening event, hospitalization
Drug(s) suspected as cause:
Didronel
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