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Dexamethasone (Dexamethasone) - Hypokalaemia - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Hypokalaemia ()

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Dexamethasone where reactions include hypokalaemia. The selected reports were submitted to the FDA during the sample period of about a year.

 Reports 1 - 30 of    Next >>

Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-08-22

Patient:

Reactions: Abdominal Pain, Thrombosis, Hyperkalaemia, Coagulopathy, Hypoglycaemia, Hypocalcaemia, Hypoxia, Hiccups, Alanine Aminotransferase Abnormal, Pneumonitis, Cough, Pain in Extremity, Hypotension, Hyperglycaemia, External Ear Pain, Haematotoxicity, Dehydration, Lower Gastrointestinal Haemorrhage, Hypofibrinogenaemia, Aspartate Aminotransferase Abnormal, Hypokalaemia, Blood Bilirubin Abnormal, Pleural Effusion, Decreased Appetite, Gamma-Glutamyltransferase Abnormal, Hyponatraemia, Hypercalcaemia, Hypophosphataemia, Diarrhoea, Hypoalbuminaemia, Hypertension, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 10 mg/m2/day divided in to 2 doses for 14 consecutive days
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Dosage: on day 1 for all patients and on days 8, 15, 22 for cns invlovment
    Indication: Acute Lymphocytic Leukaemia

Methotrexate Sodium
    Dosage: 1 dose on day 15 for no cns involvement and on days 8, 15, 22 for cns involvement
    Indication: Acute Lymphocytic Leukaemia

Hydrocortisone
    Dosage: on days 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin HCL
    Dosage: given over 15-30 minutes on day 1
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: 1.5 mg/m2/dose, max. 2 mg, by push on days 1, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Asparaginase
    Dosage: 2500 units/m2/dose as 4 weekly doses
    Indication: Acute Lymphocytic Leukaemia

Bortezomib
    Dosage: 1.3 mg/sq.m/dose on days 1, 4, 8 and 11 combined with vxld
    Indication: Acute Lymphocytic Leukaemia

Other drugs received by patient: Vancomycin; Posaconazole; Voriconazole; Levofloxacin



Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-08-20

Patient:

Reactions: Abdominal Pain, Thrombosis, Hyperkalaemia, Hypoglycaemia, Coagulopathy, Hypokalaemia, Blood Bilirubin Abnormal, Hiccups, Pleural Effusion, Hypoxia, Hypocalcaemia, Alanine Aminotransferase Abnormal, Cough, Pneumonitis, Decreased Appetite, Pain in Extremity, Hypotension, Hyperglycaemia, Gamma-Glutamyltransferase Abnormal, Hyponatraemia, External Ear Pain, Hypercalcaemia, Haematotoxicity, Hypophosphataemia, Diarrhoea, Dehydration, Hypoalbuminaemia, Lower Gastrointestinal Haemorrhage, Hypertension, Hypofibrinogenaemia, Aspartate Aminotransferase Abnormal, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bortezomib
    Dosage: 1.3 mg/sq.m/dose on days 1, 4, 8 and 11 combined with vxld
    Indication: Acute Lymphocytic Leukaemia

Vincristine
    Dosage: 1.5 mg/m2/dose, max. 2 mg, by push on days 1, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Dosage: given over 15-30 minutes on day 1
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Dosage: 10 mg/m2/day divided in to 2 doses for 14 consecutive days
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Dosage: on day 1 for all patients and on days 8, 15, 22 for cns invlovment
    Indication: Acute Lymphocytic Leukaemia

Asparaginase
    Dosage: 2500 units/m2/dose as 4 weekly doses
    Indication: Acute Lymphocytic Leukaemia

Hydrocortisone
    Dosage: on days 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: 1 dose on day 15 for no cns involvement and on days 8, 15, 22 for cns involvement
    Indication: Acute Lymphocytic Leukaemia

Other drugs received by patient: Levofloxacin; Voriconazole; Posaconazole; Vancomycin



Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-08-14

Patient:

Reactions: Thrombosis, Abdominal Pain, Hyperkalaemia, Hypoglycaemia, Coagulopathy, Hypoxia, Hypocalcaemia, Hiccups, Alanine Aminotransferase Abnormal, Cough, Pneumonitis, Pain in Extremity, Hyperglycaemia, Hypotension, External Ear Pain, Haematotoxicity, Dehydration, Lower Gastrointestinal Haemorrhage, Hypofibrinogenaemia, Aspartate Aminotransferase Abnormal, Hypokalaemia, Neuropathy Peripheral, Blood Bilirubin Abnormal, Pleural Effusion, Decreased Appetite, Hyponatraemia, Gamma-Glutamyltransferase Abnormal, Hypercalcaemia, Hypophosphataemia, Diarrhoea, Hypoalbuminaemia, Hypertension, Infection

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Vincristine
    Dosage: 1.5 mg/m2/dose, max. 2 mg, by push on days 1, 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Methotrexate
    Dosage: 1 dose on day 15 for no cns involvement and on days 8, 15, 22 for cns involvement
    Indication: Acute Lymphocytic Leukaemia

Bortezomib
    Dosage: 1.3 mg/sq.m/dose on days 1, 4, 8 and 11 combined with vxld
    Indication: Acute Lymphocytic Leukaemia

Doxorubicin Hydrochloride
    Dosage: given over 15-30 minutes on day 1
    Indication: Acute Lymphocytic Leukaemia

Asparaginase
    Dosage: 2500 units/m2/dose as 4 weekly doses
    Indication: Acute Lymphocytic Leukaemia

Cytarabine
    Dosage: on day 1 for all patients and on days 8, 15, 22 for cns invlovment
    Indication: Acute Lymphocytic Leukaemia

Hydrocortisone
    Dosage: on days 8, 15 and 22
    Indication: Acute Lymphocytic Leukaemia

Dexamethasone
    Dosage: 10 mg/m2/day divided in to 2 doses for 14 consecutive days
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia

Other drugs received by patient: Levofloxacin; Vancomycin; Posaconazole; Voriconazole



Possible Dexamethasone side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-08-06

Patient:

Reactions: Anaphylactic Reaction, Pyrexia, Headache, Hyperhidrosis, Oedema Peripheral, Cough, Muscle Spasms, Diverticular Perforation, Back Pain, Pneumonia, Anaemia, Insomnia, Neutropenia, Stridor, Chills, Constipation, Hypokalaemia, Disease Progression, Fatigue, Dizziness, Thrombocytopenia, Enteritis, Dyspnoea, Nausea, Lymphopenia, Atrial Fibrillation, Febrile Neutropenia, Rash, Lung Disorder, Diarrhoea, Arthralgia, Sepsis, Bradycardia, Asthenia

Drug(s) suspected as cause:
Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma

Elotuzumab
    Dosage: 5, 10 and 20 mg/kg
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: 40 milligram
    Administration route: Oral
    Indication: Multiple Myeloma

Elotuzumab
    Dosage: 5, 10 and 20 mg/kg



Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-08-02

Patient:

Reactions: Electrocardiogram QT Prolonged, Hypokalaemia, Hypocalcaemia, Thrombocytopenia, Lethargy, Pneumonia, Nausea, Hyperglycaemia, Atrial Fibrillation, Febrile Neutropenia, Arthralgia, Diarrhoea, Dehydration, Neutropenia, Asthenia, Leukopenia

Drug(s) suspected as cause:
Dexamethasone
    Indication: Multiple Myeloma

Treanda
    Dosage: 75 or 100mg/m2 (day 1 and 2 of ea cycle)
    Indication: Multiple Myeloma

Lenalidomide
    Dosage: 5 or 10mg (daily,days 1-21 of ea cycle)
    Administration route: Oral
    Indication: Multiple Myeloma

Other drugs received by patient: Gastroprotectant; Acetylsalicylic Acid SRT



Possible Dexamethasone side effects in

Reported by a physician from Israel on 2012-07-28

Patient:

Reactions: Febrile Neutropenia, Hyponatraemia, Pyrexia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Placebo
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Dexamethasone
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Vincristine Sulfate
    Dosage: 0.6 mg, qd
    Start date: 2012-06-24
    End date: 2012-06-24

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Ondansetron HCL
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Cytoxan
    Dosage: 172 mg, qd
    Indication: Chemotherapy
    Start date: 2012-06-19
    End date: 2012-06-20

Ondansetron
    Administration route: Oral
    Indication: Prophylaxis of Nausea and Vomiting
    Start date: 2012-06-18
    End date: 2012-06-22

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Blinded PRE Trial Therapy
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Dexamethasone
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Cisplatin
    Dosage: 46.2 mg/kg, qd
    Indication: Chemotherapy
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Vincristine Sulfate
    Dosage: 0.66 mg, qd
    Start date: 2012-07-01
    End date: 2012-07-01

Etoposide
    Dosage: 33 mg, qd
    Indication: Chemotherapy
    Start date: 2012-06-18
    End date: 2012-06-20

Blinded PRE Trial Therapy
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Placebo
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Vincristine Sulfate
    Dosage: 0.66 mg, qd
    Indication: Chemotherapy
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Post Trial Therapy
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Blinded Ondansetron HCL
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Blinded Post Trial Therapy
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Other drugs received by patient: Dexacort (Dexamethasone Sodium Phosphate); Mesna; Resprim; Diamox



Possible Dexamethasone side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-07-23

Patient:

Reactions: Electrocardiogram QT Prolonged, Hypokalaemia, Hypocalcaemia, Thrombocytopenia, Lethargy, Pneumonia, Nausea, Hyperglycaemia, Febrile Neutropenia, Atrial Fibrillation, Arthralgia, Diarrhoea, Dehydration, Neutropenia, Asthenia, Leukopenia

Drug(s) suspected as cause:
Bendamustine Hydrochloride
    Dosage: 75 or 100mg/m2
    Indication: Multiple Myeloma

Revlimid
    Dosage: 5 or 10mg
    Administration route: Oral
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Other drugs received by patient: Gastroprotectant; Aspirin



Possible Dexamethasone side effects in

Reported by a physician from Israel on 2012-07-17

Patient:

Reactions: Febrile Neutropenia, Hyponatraemia, Pyrexia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Blinded Post Trial Therapy
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Ondansetron HCL
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Placebo
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Blinded Post Trial Therapy
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Blinded PRE Trial Therapy
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Cisplatin
    Dosage: 46.2 mg/kg, qd
    Indication: Chemotherapy
    Start date: 2012-06-18
    End date: 2012-06-18

Cytoxan
    Dosage: 172 mg, qd
    Indication: Chemotherapy
    Start date: 2012-06-19
    End date: 2012-06-20

Dexamethasone
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Vincristine Sulfate
    Dosage: 0.66 mg, qd
    Indication: Chemotherapy
    Start date: 2012-06-18
    End date: 2012-06-18

Dexamethasone
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Ondansetron HCL
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded PRE Trial Therapy
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Placebo
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-19
    End date: 2012-06-20

Vincristine Sulfate
    Dosage: 0.6 mg, qd
    Start date: 2012-06-24
    End date: 2012-06-24

Etoposide
    Dosage: 33 mg, qd
    Indication: Chemotherapy
    Start date: 2012-06-18
    End date: 2012-06-20

Ondansetron
    Administration route: Oral
    Indication: Prophylaxis of Nausea and Vomiting
    Start date: 2012-06-18
    End date: 2012-06-22

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Vincristine Sulfate
    Dosage: 0.66 mg, qd
    Start date: 2012-07-01
    End date: 2012-07-01

Blinded Aprepitant
    Administration route: Oral
    Start date: 2012-06-18
    End date: 2012-06-18

Other drugs received by patient: Dexacort (Dexamethasone Sodium Phosphate); Resprim; Diamox; Mesna



Possible Dexamethasone side effects in 68 year old female

Reported by a physician from United States on 2012-07-10

Patient: 68 year old female, weighing 80.0 kg (176.0 pounds)

Reactions: Syncope, Hypokalaemia, Renal Failure Acute

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-02

Cisplatin
    Dosage: 100mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-02

Cytarabine
    Dosage: 4gm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-03

Dexamethasone
    Dosage: 40mg every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2012-06-02



Possible Dexamethasone side effects in

Reported by a physician from Japan on 2012-06-29

Patient:

Reactions: Nausea, Anaemia, Febrile Neutropenia, Hyponatraemia, Toxicity To Various Agents, Peripheral Sensory Neuropathy, Haematotoxicity, Hypokalaemia, Fatigue, Diarrhoea, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Bortezomib
    Dosage: days 1, 4, 8 and 11 (1 mg/ m2 in cohort 1 and 1.3 mg/ m2 in cohort 2)
    Indication: Multiple Myeloma

Doxorubicin HCL
    Dosage: days 1-4

Dexamethasone
    Dosage: days 1-2, 4-5, 8-9 and 11-12
    Administration route: Oral
    Indication: Multiple Myeloma

Doxorubicin HCL
    Dosage: days 1-4
    Indication: Multiple Myeloma



Possible Dexamethasone side effects in

Reported by a physician from Japan on 2012-06-28

Patient:

Reactions: Nausea, Anaemia, Febrile Neutropenia, Hyponatraemia, Toxicity To Various Agents, Peripheral Sensory Neuropathy, Haematotoxicity, Hypokalaemia, Fatigue, Diarrhoea, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Bortezomib
    Dosage: days 1, 4, 8 and 11 (1 mg/ m2 in cohort 1 and 1.3 mg/ m2 in cohort 2)
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: days 1-2, 4-5, 8-9 and 11-12
    Administration route: Oral
    Indication: Multiple Myeloma

Doxorubicin HCL
    Dosage: days 1-4

Doxorubicin HCL
    Dosage: days 1-4
    Indication: Multiple Myeloma



Possible Dexamethasone side effects in

Reported by a physician from Japan on 2012-06-27

Patient:

Reactions: Nausea, Anaemia, Febrile Neutropenia, Hyponatraemia, Toxicity To Various Agents, Peripheral Sensory Neuropathy, Haematotoxicity, Hypokalaemia, Fatigue, Diarrhoea, Neutropenia, Thrombocytopenia

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: days 1-4
    Indication: Multiple Myeloma

Bortezomib
    Dosage: days 1, 4, 8 and 11 (1 mg/ m2 in cohort 1 and 1.3 mg/ m2 in cohort 2)
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: days 1-2, 4-5, 8-9 and 11-12
    Administration route: Oral
    Indication: Multiple Myeloma



Possible Dexamethasone side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-20

Patient: 64 year old male

Reactions: Diarrhoea, Electrolyte Imbalance, Blood Magnesium Decreased, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Thalidomide
    Indication: Multiple Myeloma

Bendamustine Hydrochloride
    Dosage: 100 mg/m2;iv 50 mg/m2;iv
    Indication: Multiple Myeloma
    Start date: 2011-09-28
    End date: 2012-05-09

Dexamethasone
    Indication: Multiple Myeloma

Other drugs received by patient: Acyclovir; Ondansetron; Cotrim; Fluconazole; Lansoprazole



Possible Dexamethasone side effects in 64 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2012-06-19

Patient: 64 year old male

Reactions: Diarrhoea, Blood Magnesium Decreased, Electrolyte Imbalance, Hypokalaemia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Thalidomide
    Dosage: regimen 1
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Treanda
    Dosage: cyclic
    Indication: Multiple Myeloma
    Start date: 2011-09-28
    End date: 2012-05-09

Treanda
    Dosage: cyclic, regimen 2

Other drugs received by patient: Acyclovir; Fluconazole; Lansoprazole; Cotrim; Ondansetron



Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-06-15

Patient:

Reactions: Anaemia, Multiple Myeloma, Toxicity To Various Agents, Hypokalaemia, Death, Hypophosphataemia, Neuropathy Peripheral, Fatigue, Thrombocytopenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carfilzomib
    Dosage: days 8, 9, 15, 16 every 28 days
    Indication: Multiple Myeloma

Melphalan Hydrochloride
    Indication: Multiple Myeloma

Steroids NOS
    Indication: Multiple Myeloma

Doxorubicin HCL
    Dosage: 1.5 to 3 mg/m^2/day
    Indication: Multiple Myeloma

Lenalidomide
    Indication: Multiple Myeloma

Cisplatin
    Dosage: (3-5 mg/m^2/day) 16 days continuous infusion
    Indication: Multiple Myeloma

Carfilzomib
    Dosage: day 1, 2

Thalidomide
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: in the absence of at least partial response (pr), dex increased to 20 mg
    Indication: Multiple Myeloma

Bortezomib
    Indication: Multiple Myeloma



Possible Dexamethasone side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-06-08

Patient:

Reactions: Anaemia, Toxicity To Various Agents, Multiple Myeloma, Hypokalaemia, Death, Hypophosphataemia, Fatigue, Neuropathy Peripheral, Thrombocytopenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Carfilzomib
    Dosage: days 8, 9, 15, 16 every 28 days
    Indication: Multiple Myeloma

Melphalan Hydrochloride
    Indication: Multiple Myeloma

Cisplatin
    Dosage: (3-5 mg/m^2/day) 16 days continuous infusion
    Indication: Multiple Myeloma

Dexamethasone
    Dosage: in the absence of at least partial response (pr), dex increased to 20 mg
    Indication: Multiple Myeloma

Thalidomide
    Indication: Multiple Myeloma

Bortezomib
    Indication: Multiple Myeloma

Lenalidomide
    Indication: Multiple Myeloma

Steroids NOS
    Indication: Multiple Myeloma

Doxorubicin HCL
    Dosage: 1.5 to 3 mg/m^2/day
    Indication: Multiple Myeloma

Carfilzomib
    Dosage: day 1, 2



Possible Dexamethasone side effects in 78 year old female

Reported by a physician from United States on 2012-05-16

Patient: 78 year old female, weighing 62.9 kg (138.4 pounds)

Reactions: Soft Tissue Infection, Status Epilepticus, Hypertension, Fall, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-07-12
    End date: 2011-10-15

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-07-12
    End date: 2011-10-17

Velcade
    Dosage: 1.3 milligram/sq. meter
    Indication: Multiple Myeloma
    Start date: 2011-07-12
    End date: 2011-10-14

Other drugs received by patient: Aspirin; Zosyn; Cefazolin; Ciprofloxacin



Possible Dexamethasone side effects in 78 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-10

Patient: 78 year old female, weighing 62.6 kg (137.7 pounds)

Reactions: Abscess Soft Tissue, Status Epilepticus, Hypertension, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Start date: 2011-07-12

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Start date: 2011-10-04
    End date: 2011-10-17

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Start date: 2011-10-04
    End date: 2011-10-15

Bortezomib
    Dosage: 1.3 milligram/sq. meter
    Start date: 2011-07-12

Bortezomib
    Dosage: 1.3 milligram/sq. meter
    Start date: 2011-10-04
    End date: 2011-10-14

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Start date: 2011-07-12

Other drugs received by patient: Aspirin; Keppra; Atenolol; Aspirin



Possible Dexamethasone side effects in 78 year old female

Reported by a physician from United States on 2012-05-10

Patient: 78 year old female, weighing 62.9 kg (138.4 pounds)

Reactions: Soft Tissue Infection, Status Epilepticus, Fall, Hypertension, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-07-12
    End date: 2011-10-17

Velcade
    Dosage: 1.3 milligram/sq. meter
    Indication: Multiple Myeloma
    Start date: 2011-07-12
    End date: 2011-10-14

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-07-12
    End date: 2011-10-15

Other drugs received by patient: Aspirin; Zosyn; Cefazolin; Ciprofloxacin



Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-04-09

Patient:

Reactions: Hyperkalaemia, Hyperglycaemia, Anaemia, Disease Progression, Hyperuricaemia, Hypokalaemia, Therapeutic Response Decreased, Fatigue, Hypomagnesaemia, Amyloidosis, Neutropenia, Blood Creatinine Increased, Thrombocytopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Melphalan Hydrochloride
    Dosage: 5 milligram/sq. meter

Dexamethasone
    Dosage: 40 milligram

Revlimid
    Dosage: 10 milligram
    Administration route: Oral

Other drugs received by patient: Proton Pump Inhibitor; Aspirin



Possible Dexamethasone side effects in 15 year old male

Reported by a consumer/non-health professional from United States on 2012-04-03

Patient: 15 year old male, weighing 110.0 kg (242.0 pounds)

Reactions: Hypersensitivity, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cytarabine
    Dosage: last dose on 24nov09; 60 mg it:15oct09
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Oncaspar
    Dosage: lats dose:05oct2009
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Cyclophosphamide
    Dosage: last dose on 27nov09. 2352mg:05oct2009
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Methotrexate
    Dosage: last dose on 09nov2009: 24000 mg iv mtx
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Daunorubicin HCL
    Dosage: last dose:02oct2009
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Vincristine Sulfate
    Dosage: last dose:15oct2009
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Etoposide
    Dosage: last dose on 27nov09.
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Asparaginase
    Dosage: last dose on 06jan10.
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Dexamethasone
    Dosage: last dose:21oct2009
    Start date: 2009-04-08

Sprycel
    Dosage: last dose on 27dec09. 1820mg:14oct2009
    Administration route: Oral
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08

Hydrocortisone
    Dosage: last dose on 24nov2009, 15oct2009
    Indication: Acute Lymphocytic Leukaemia
    Start date: 2009-04-08



Possible Dexamethasone side effects in

Reported by a physician from United States on 2012-03-12

Patient:

Reactions: Confusional State, Abdominal Pain, Pain, Multiple Myeloma, Pelvic Pain, Hypokalaemia, Fatigue, Neuropathy Peripheral, Upper Respiratory Tract Infection, Oedema, Hypocalcaemia, Thrombocytopenia, Cough, Back Pain, Vomiting, Dyspnoea, Cellulitis, Pneumonia, Nausea, Anaemia, Diarrhoea, Neutropenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: as 90 min infusion on day 1 of cycle 1 with other doses given over 30-60 min
    Indication: Multiple Myeloma

Lenalidomide
    Indication: Multiple Myeloma

Dexamethasone
    Indication: Multiple Myeloma

Bortezomib
    Indication: Multiple Myeloma

Other drugs received by patient: Aspirin



Possible Dexamethasone side effects in

Reported by a health professional (non-physician/pharmacist) from United States on 2012-03-07

Patient:

Reactions: Confusional State, Abdominal Pain, Hypersensitivity, Pain, Pulmonary Embolism, Pelvic Pain, Multiple Myeloma, Fall, Hypokalaemia, Thrombophlebitis Septic, Death, Fatigue, Neuropathy Peripheral, Basal Cell Carcinoma, Upper Respiratory Tract Infection, Balance Disorder, Oedema, Hypocalcaemia, Thrombocytopenia, Cough, Back Pain, Dyspnoea, Vomiting, Dysphagia, Cellulitis, Pneumonia, Nausea, Anaemia, Respiratory Distress, Hypophosphataemia, Syncope, Diarrhoea, Neutropenia, Leukopenia

Adverse event resulted in: death

Drug(s) suspected as cause:
Doxorubicin HCL
    Dosage: 3 milligram/sq. meter

Dexamethasone
    Dosage: 20 milligram

Revlimid
    Dosage: 5 milligram
    Administration route: Oral

Dexamethasone
    Dosage: 40 milligram
    Indication: Multiple Myeloma

Bortezomib
    Dosage: 1 milligram/sq. meter
    Indication: Multiple Myeloma

Revlimid
    Dosage: 10 milligram
    Administration route: Oral
    Indication: Multiple Myeloma

Bortezomib
    Dosage: .7 milligram/sq. meter

Doxorubicin HCL
    Dosage: 4 milligram/sq. meter
    Indication: Multiple Myeloma

Other drugs received by patient: Heparin; Glucocorticosteroids; Aspirin; Warfarin Sodium



Possible Dexamethasone side effects in

Reported by a physician from Australia on 2012-02-28

Patient:

Reactions: Hyperkalaemia, Pain, Multiple Myeloma, Peripheral Sensory Neuropathy, Constipation, Hypokalaemia, Cerebral Haemorrhage, Fatigue, Neutropenic Infection, Neuropathy Peripheral, Hypocalcaemia, Dizziness, Thrombocytopenia, Blood Creatinine Increased, Vomiting, Atrial Flutter, Hyperglycaemia, Anaemia, Alanine Aminotransferase Increased, Febrile Neutropenia, Hyponatraemia, Intestinal Obstruction, Hypercalcaemia, Diarrhoea, Neutropenia, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Istodax
    Dosage: 8-14 mg/m2
    Indication: Multiple Myeloma

Dexamethasone
    Administration route: Oral
    Indication: Multiple Myeloma

Bortezomib
    Indication: Multiple Myeloma

Other drugs received by patient: Sulfamethoxazole; Trimethoprim; Bisphosphonates; Neupogen; Valaciclovir; Neupogen; Neupogen



Possible Dexamethasone side effects in male

Reported by a health professional (non-physician/pharmacist) from Canada on 2012-02-02

Patient: male, weighing 57.2 kg (125.8 pounds)

Reactions: Productive Cough, Blood Magnesium Decreased, Hyperuricaemia, Hypokalaemia, Fatigue, Ecchymosis, Oedema, Hypocalcaemia, Blood Creatinine Increased, Decreased Appetite, Dyspnoea, Vomiting, Hyperglycaemia, Hypotension, Haemorrhoids, Febrile Neutropenia, General Physical Health Deterioration, Blood Bicarbonate Decreased, Hepatic Steatosis, Hypophosphataemia, Diarrhoea, Insomnia, Hypothyroidism, Neutropenia, Infection

Adverse event resulted in: death, hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 20 milligram
    Indication: Multiple Myeloma
    Start date: 2010-11-04

Lenalidomide
    Dosage: 25 milligram
    Administration route: Oral
    Start date: 2011-12-22
    End date: 2012-01-10

Dexamethasone
    Dosage: 12 milligram
    Start date: 2011-12-22
    End date: 2012-01-10

Lenalidomide
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2010-11-04

Other drugs received by patient: Prilosec; Synthroid; Travoprost and Timolol; Potassium Chloride; Acetaminophen; Sodium Chloride; Prochlorperazine; Serax; Levophed; Alendronate Sodium; Ventolin; Atrovent; Xalatan; Solu-Cortef; Timolol Maleate; Pantoprazole Sodium; Potassium Phosphates; Sodium Chloride; Ensure; Inhaler; Senokot; Versed; Pepcid; Mucomyst; Amlodipine; Pravastatin; Heparin; FLU Vaccine; Pravastatin; Colace; Lasix; Alendronate Sodium; Euro-D; Crestor; Normal Saline W / KCL; Gravol TAB; Magnesium Sulfate; Niaspan; Benadryl; Prilosec; Synthroid; Dilaudid; Dilaudid; Calcium; Sodium Chloride; Zovirax; Flexeril; Potassium Chloride; Aspirin; Synthroid; Dilaudid; Calcium Gluconate; Acetaminophen; Anusol; Sodium Chloride; Scopolamine; Euro-D; Lovenox; Sodium Chloride; Heparin; Solu-Cortef; Vitamin D; Hydromorphone HCL; Lasix; Sodium Chloride; Lactulose; Sodium Chloride; Lyrica; Pneumovax 23



Possible Dexamethasone side effects in female

Reported by a physician from United Kingdom on 2012-02-02

Patient: female, weighing 113.6 kg (249.9 pounds)

Reactions: Fatigue, Nausea, Blood Creatinine Increased, Thrombocytopenia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 40mg every 3 weeks
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-23

Cytarabine
    Dosage: 2mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-25

Cisplatin
    Dosage: 100mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-24

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-23



Possible Dexamethasone side effects in 65 year old female

Reported by a physician from United States on 2012-01-03

Patient: 65 year old female, weighing 86.0 kg (189.2 pounds)

Reactions: International Normalised Ratio Increased, Acidosis, Renal Failure Chronic, Hypokalaemia, Sepsis, Hypomagnesaemia, Hypocalcaemia, Kidney Infection, Blood Creatinine Increased, Lymphocyte Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Bortezomib
    Dosage: 1.3 milligram/sq. meter
    Indication: Multiple Myeloma
    Start date: 2011-09-20
    End date: 2011-09-30

Cefazolin

Revlimid
    Dosage: 25 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-09-20
    End date: 2011-10-03

Dexamethasone
    Dosage: 20 milligram
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-09-20
    End date: 2011-10-01

Other drugs received by patient: Fluids; Warfarin Sodium; Antibiotics; Electrolyte Replacement; Aspirin



Possible Dexamethasone side effects in 65 year old female

Reported by a physician from United States on 2011-12-29

Patient: 65 year old female, weighing 86.0 kg (189.2 pounds)

Reactions: International Normalised Ratio Increased, Acidosis, Renal Failure Chronic, Hypokalaemia, Hypomagnesaemia, Sepsis, Hypocalcaemia, Kidney Infection, Blood Creatinine Increased, Lymphocyte Count Decreased

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Velcade
    Dosage: 1.3 mg/m2, cyclic
    Indication: Multiple Myeloma
    Start date: 2011-09-20
    End date: 2011-09-30

Dexamethasone
    Dosage: 20 mg, cyclic
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-09-20
    End date: 2011-10-01

Cefazolin
    Indication: Product Used FOR Unknown Indication

Lenalidomide
    Dosage: 25 mg, cyclic
    Administration route: Oral
    Indication: Multiple Myeloma
    Start date: 2011-09-20
    End date: 2011-10-03

Other drugs received by patient: Aspirin; Warfarin Sodium



Possible Dexamethasone side effects in female

Reported by a physician from United Kingdom on 2011-12-19

Patient: female, weighing 113.6 kg (249.9 pounds)

Reactions: Fatigue, Nausea, Thrombocytopenia, Blood Creatinine Increased, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Cisplatin
    Dosage: 100mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-24

Cytarabine
    Dosage: 2mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-25

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-23

Dexamethasone
    Dosage: 40mg every 3 weeks
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-23



Possible Dexamethasone side effects in female

Reported by a physician from United Kingdom on 2011-12-08

Patient: female, weighing 113.6 kg (249.9 pounds)

Reactions: Fatigue, Nausea, Blood Creatinine Increased, Thrombocytopenia, Hypokalaemia

Adverse event resulted in: hospitalization

Drug(s) suspected as cause:
Dexamethasone
    Dosage: 40mg every 3 weeks
    Administration route: Oral
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-23

Cytarabine
    Dosage: 2mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-25

Ofatumumab
    Dosage: 1000mg cyclic
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-23

Cisplatin
    Dosage: 100mgm2 every 3 weeks
    Indication: Diffuse Large B-Cell Lymphoma Recurrent
    Start date: 2011-11-24



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