DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Depocyt (Cytarabine) - Mucosal Inflammation - Suspected Cause - Side Effect Reports

 
 



Index of reports > Cases with Mucosal Inflammation (7)

Below is the selection of side effect reports (a.k.a. adverse event reports) related to Depocyt (Cytarabine) where reactions include mucosal inflammation. The selected reports were submitted to the FDA during the sample period of about a year.

Possible Depocyt side effects in 14 year old male

Reported by a consumer/non-health professional from Norway on 2012-06-10

Patient: 14 year old male

Reactions: C-Reactive Protein, Listless, Arachnoiditis, Deafness, Pyrexia, Headache, Somnolence, Fall, Neurotoxicity, Fatigue, Chest Pain, Coordination Abnormal, Sinusitis, Decreased Appetite, Ataxia, Cognitive Disorder, Mucosal Inflammation, Medulloblastoma Recurrent, Dysarthria, Metastases To Spine, Visual Impairment, Hypothyroidism, Neutropenia

Adverse event resulted in: life threatening event

Drug(s) suspected as cause:
Depocyt
    Dosage: initially given every other week,then monthly,cumulative dose 650mg,resatarted after 18months
    Indication: Medulloblastoma

Etoposide
    Dosage: 25 mg/day on alternate days; max 100mg daily (50 mg/m2 cumu dose:11.5 g/m2 over 31 months
    Administration route: Oral
    Indication: Medulloblastoma

Celecoxib
    Dosage: also taken 400mg bid 430mg/m2
    Administration route: Oral
    Indication: Medulloblastoma

Thalidomide
    Dosage: also taken 50mg 3mg/kg
    Administration route: Oral
    Indication: Medulloblastoma

Other drugs received by patient: Prednisolone Hydrogen Succinate; Dexamethasone



Possible Depocyt side effects in male

Reported by a health professional (non-physician/pharmacist) from Norway on 2012-05-30

Patient: male, weighing 75.0 kg (165.0 pounds)

Reactions: Confusional State, Listless, Arachnoiditis, Deafness, Pyrexia, Headache, Somnolence, Fall, Fatigue, C-Reactive Protein Increased, Chest Pain, Sinusitis, Decreased Appetite, Ataxia, Hypoaesthesia, Paraesthesia, Haematotoxicity, Mucosal Inflammation, Dysarthria, Anxiety, Neutropenia

Adverse event resulted in: hospitalization, disablity

Drug(s) suspected as cause:
Etoposide
    Dosage: 25mg every other day for the last 8 months; cumulative dose of 11.5 g/m2 over 31 months
    Administration route: Oral

Thalidomide
    Dosage: maximal dose 200mg daily (3 mg/kg)
    Administration route: Oral
    Indication: Medulloblastoma Recurrent

Etoposide
    Dosage: maximal dose 100mg daily (50 mg/m2); cumulative dose of 11.5 g/m2 over 31 months
    Administration route: Oral
    Indication: Medulloblastoma Recurrent

Depocyt
    Dosage: 50mg on alternate weeks, gradually increased to every other month; 3-month break after 7th course
    Indication: Medulloblastoma Recurrent

Celecoxib
    Dosage: maximal dose 400mg x 2 daily (430 mg/m2)
    Administration route: Oral
    Indication: Medulloblastoma Recurrent

Other drugs received by patient: Prednisolone Sodium Succinate; Dexamethasone



Possible Depocyt side effects in 20 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2012-04-02

Patient: 20 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Mucosal Inflammation, Herpes Simplex, Hyperkalaemia, Febrile Bone Marrow Aplasia, Hepatic Enzyme Increased

Drug(s) suspected as cause:
Doxorubicin HCL

Doxorubicin HCL

Dexamethasone

Depocyt
    Indication: Burkitt's Lymphoma

Dexamethasone

Cytarabine

Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Vincristine

Methotrexate
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: day 1
    Indication: Burkitt's Lymphoma

Doxorubicin HCL

Doxorubicin HCL

Cyclophosphamide

Methotrexate

Cytarabine
    Indication: Burkitt's Lymphoma

Doxorubicin HCL

Doxorubicin HCL

Vincristine

Methotrexate

Prednisone TAB
    Indication: Burkitt's Lymphoma

Dexamethasone
    Indication: Burkitt's Lymphoma

Cytarabine

Cyclophosphamide
    Dosage: a1-a3

Cyclophosphamide

Vincristine
    Indication: Burkitt's Lymphoma

Vincristine

Doxorubicin HCL

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Cyclophosphamide

Dexamethasone

Methotrexate

Cytarabine



Possible Depocyt side effects in 20 year old male

Reported by a individual with unspecified qualification from Germany on 2011-12-16

Patient: 20 year old male

Reactions: Mucosal Inflammation, Pneumocystis Jiroveci Pneumonia, Hyperkalaemia, Herpes Simplex, Bone Marrow Failure, Hepatic Enzyme Increased

Drug(s) suspected as cause:
Cyclophosphamide
    Dosage: 300 mg abs. in a1-a3

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Depocyt
    Indication: Burkitt's Lymphoma

Vincristine
    Indication: Burkitt's Lymphoma

Dexamethasone
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Lymphoma



Possible Depocyt side effects in 20 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2011-12-08

Patient: 20 year old male

Reactions: Mucosal Inflammation, Pneumocystis Jiroveci Pneumonia, Herpes Simplex, Hyperkalaemia, Aplasia, Hepatic Enzyme Increased

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Dexamethasone
    Indication: Burkitt's Lymphoma

Rituximab
    Indication: Burkitt's Lymphoma

Vincristine
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Depocyt
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: 300 mg abs. in a1-a3



Possible Depocyt side effects in 20 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2011-11-23

Patient: 20 year old male

Reactions: Pneumocystis Jiroveci Pneumonia, Mucosal Inflammation, Hyperkalaemia, Herpes Simplex, Febrile Bone Marrow Aplasia, Hepatic Enzyme Increased

Drug(s) suspected as cause:
Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Methotrexate
    Indication: Burkitt's Lymphoma

Cytarabine

Dexamethasone
    Indication: Burkitt's Lymphoma

Methotrexate

Cytarabine

Doxorubicin HCL

Cytarabine
    Indication: Burkitt's Lymphoma

Rituximab
    Dosage: day 1
    Indication: Burkitt's Lymphoma

Doxorubicin HCL

Dexamethasone

Prednisone TAB
    Indication: Burkitt's Lymphoma

Cyclophosphamide

Dexamethasone

Cytarabine

Cyclophosphamide

Cyclophosphamide
    Dosage: a1-a3

Vincristine

Vincristine

Depocyt
    Indication: Burkitt's Lymphoma

Doxorubicin HCL

Methotrexate

Cyclophosphamide

Vincristine
    Indication: Burkitt's Lymphoma

Vincristine

Dexamethasone

Methotrexate



Possible Depocyt side effects in 20 year old male

Reported by a health professional (non-physician/pharmacist) from Germany on 2011-11-23

Patient: 20 year old male

Reactions: Mucosal Inflammation, Pneumocystis Jiroveci Pneumonia, Hyperkalaemia, Herpes Simplex, Febrile Bone Marrow Aplasia, Hepatic Enzyme Increased

Drug(s) suspected as cause:
Cyclophosphamide

Dexamethasone
    Indication: Burkitt's Lymphoma

Doxorubicin HCL

Dexamethasone

Doxorubicin HCL

Vincristine
    Indication: Burkitt's Lymphoma

Vincristine

Methotrexate
    Indication: Burkitt's Lymphoma

Methotrexate

Cyclophosphamide
    Indication: Burkitt's Lymphoma

Cyclophosphamide
    Dosage: a1-a3

Doxorubicin HCL

Cyclophosphamide

Cyclophosphamide

Dexamethasone

Methotrexate

Methotrexate

Cytarabine
    Indication: Burkitt's Lymphoma

Prednisone TAB
    Indication: Burkitt's Lymphoma

Doxorubicin HCL
    Indication: Burkitt's Lymphoma

Vincristine

Cytarabine

Cytarabine

Vincristine

Dexamethasone

Cytarabine

Rituximab
    Dosage: day 1
    Indication: Burkitt's Lymphoma

Depocyt
    Indication: Burkitt's Lymphoma

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017