Index of reports
> Cases with Headache (9)
Below is the selection of side effect reports (a.k.a. adverse event reports) related to Depocyt (Cytarabine) where reactions include headache. The selected reports were submitted to the FDA during the sample period of about a year.
Possible Depocyt side effects in 14 year old male
Reported by a consumer/non-health professional from Norway on 2012-06-10
Patient: 14 year old male
Reactions: C-Reactive Protein, Listless, Arachnoiditis, Deafness, Pyrexia, Headache, Somnolence, Fall, Neurotoxicity, Fatigue, Chest Pain, Coordination Abnormal, Sinusitis, Decreased Appetite, Ataxia, Cognitive Disorder, Mucosal Inflammation, Medulloblastoma Recurrent, Dysarthria, Metastases To Spine, Visual Impairment, Hypothyroidism, Neutropenia
Adverse event resulted in: life threatening event
Drug(s) suspected as cause:
Depocyt
Dosage: initially given every other week,then monthly,cumulative dose 650mg,resatarted after 18months
Indication: Medulloblastoma
Etoposide
Dosage: 25 mg/day on alternate days; max 100mg daily (50 mg/m2 cumu dose:11.5 g/m2 over 31 months
Administration route: Oral
Indication: Medulloblastoma
Celecoxib
Dosage: also taken 400mg bid 430mg/m2
Administration route: Oral
Indication: Medulloblastoma
Thalidomide
Dosage: also taken 50mg 3mg/kg
Administration route: Oral
Indication: Medulloblastoma
Other drugs received by patient: Prednisolone Hydrogen Succinate; Dexamethasone
Possible Depocyt side effects in male
Reported by a health professional (non-physician/pharmacist) from Norway on 2012-05-30
Patient: male, weighing 75.0 kg (165.0 pounds)
Reactions: Confusional State, Listless, Arachnoiditis, Deafness, Pyrexia, Headache, Somnolence, Fall, Fatigue, C-Reactive Protein Increased, Chest Pain, Sinusitis, Decreased Appetite, Ataxia, Hypoaesthesia, Paraesthesia, Haematotoxicity, Mucosal Inflammation, Dysarthria, Anxiety, Neutropenia
Adverse event resulted in: hospitalization, disablity
Drug(s) suspected as cause:
Etoposide
Dosage: 25mg every other day for the last 8 months; cumulative dose of 11.5 g/m2 over 31 months
Administration route: Oral
Thalidomide
Dosage: maximal dose 200mg daily (3 mg/kg)
Administration route: Oral
Indication: Medulloblastoma Recurrent
Etoposide
Dosage: maximal dose 100mg daily (50 mg/m2); cumulative dose of 11.5 g/m2 over 31 months
Administration route: Oral
Indication: Medulloblastoma Recurrent
Depocyt
Dosage: 50mg on alternate weeks, gradually increased to every other month; 3-month break after 7th course
Indication: Medulloblastoma Recurrent
Celecoxib
Dosage: maximal dose 400mg x 2 daily (430 mg/m2)
Administration route: Oral
Indication: Medulloblastoma Recurrent
Other drugs received by patient: Prednisolone Sodium Succinate; Dexamethasone
Possible Depocyt side effects in female
Reported by a health professional (non-physician/pharmacist) from United States on 2012-05-29
Patient: female
Reactions: Vomiting, Nausea, Dizziness, Headache
Drug(s) suspected as cause:
Depocyt
Other drugs received by patient: Dexamethasone
Possible Depocyt side effects in 49 year old male
Reported by a physician from United Kingdom on 2012-04-11
Patient: 49 year old male
Reactions: Dyskinesia, Nuclear Magnetic Resonance Imaging Brain Abnormal, Headache
Drug(s) suspected as cause:
Depocyt
Other drugs received by patient: Acyclovir; Imatinib Mesylate; Fluconazole; Cotrim
Possible Depocyt side effects in 48 year old male
Reported by a physician from France on 2012-04-02
Patient: 48 year old male
Reactions: Agranulocytosis, Anaemia, Pain, Sepsis, Neoplasm Progression, Pyrexia, Headache, Thrombocytopenia, Prolymphocytic Leukaemia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Ciprofloxacin
Dosage: 500 mg;bid;iv
Indication: Sepsis
Start date: 2012-02-18
End date: 2012-02-27
Depocyt
Dosage: 50 mg;qow;inth
Indication: Prolymphocytic Leukaemia
Start date: 2012-01-14
End date: 2012-01-31
Augmentin '125'
Dosage: 1 gm;tid;iv
Indication: Sepsis
Start date: 2012-02-18
End date: 2012-02-27
Other drugs received by patient: Coversyl / 00790702 /; Domperidone; Valacyclovir Hydrochloride; Adancor; Procoralan; Atenolol; Pantoprazole; Azathioprine; Atorvastatin; Clopidogrel Bisulfate and Aspirin; Bactrim; Gaviscon / 00237601 /
Possible Depocyt side effects in 63 year old female
Reported by a physician from Austria on 2012-03-15
Patient: 63 year old female, weighing 51.0 kg (112.2 pounds)
Reactions: Dysphagia, Dehydration, Hypophagia, Nervous System Disorder, Headache, Asthenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Depocyt
Other drugs received by patient: Levothyroxine Sodium; Fortecortin / 00016001 /; Hydal; Elomel; Pantoloc / 01263201 /; Acecomb; Zofran; Vertirosan / 00019501 /; Bisoprolol Fumarate
Possible Depocyt side effects in
Reported by a physician from Italy on 2012-01-25
Patient:
Reactions: Vision Blurred, Headache
Drug(s) suspected as cause:
Depocyt
Other drugs received by patient: Cyclophosphamide; Cytarabine; Etoposide; Dexamethasone; Vincristine; Doxorubicin HCL; Rituximab; Ifosfamide; Methotrexate
Possible Depocyt side effects in male
Reported by a physician from Norway on 2011-12-28
Patient: male, weighing 75.0 kg (165.0 pounds)
Reactions: Confusional State, Arachnoiditis, Ataxia, Deafness, Pyrexia, Hypoaesthesia, Headache, Somnolence, Fall, Paraesthesia, Anxiety, Dysarthria, C-Reactive Protein Increased, Chest Pain, Neutropenia
Adverse event resulted in: hospitalization
Drug(s) suspected as cause:
Depocyt
Other drugs received by patient: Dexamethasone; Thalidomide; Celecoxib; Prednisolone; Etoposide
Possible Depocyt side effects in 70 year old male
Reported by a physician from Netherlands on 2011-11-16
Patient: 70 year old male
Reactions: Bedridden, Confusional State, Toxic Encephalopathy, Urinary Incontinence, Motor Dysfunction, Sensory Loss, Nuclear Magnetic Resonance Imaging Brain Abnormal, Faecal Incontinence, Headache, Culture Urine Positive, Somnolence, Delirium, Muscle Spasms, Candidiasis, Oxygen Saturation Decreased
Adverse event resulted in: death, hospitalization
Drug(s) suspected as cause:
Depocyt
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