This is an index of side effect / adverse reaction reports (a.k.a. adverse event reports) related to Daraprim (Pyrimethamine) and submitted to the FDA during the sample period of about a year. The information is not vetted and should not be considered as verified clinical evidence.
Reports by Event Outcome
All Cases (4)
Death (1)
Disability (1)
Reports by Reaction Type
Pancytopenia (2),
Blood Folate Increased (1),
Headache (1),
Transaminases Increased (1),
Haemodynamic Instability (1),
Speech Disorder (1),
Fatigue (1),
Palpitations (1),
Blindness Unilateral (1),
Abdominal Distension (1),
Maculopathy (1),
Rash Generalised (1)
Possible Daraprim side effects in 44 year old female
Reported by a consumer/non-health professional from United States on 2012-07-31
Patient: 44 year old female, weighing 77.1 kg (169.6 pounds)
Reactions: Rash Generalised, Hypophagia, Dehydration, Drug Hypersensitivity, Influenza Like Illness
Drug(s) suspected as cause:
Daraprim
Dosage: 100 mg;x1;po 25 mg;qd;po
Administration route: Oral
Indication: Toxoplasmosis
Start date: 2012-06-30
End date: 2012-06-30
Daraprim
Dosage: 100 mg;x1;po 25 mg;qd;po
Administration route: Oral
Indication: Toxoplasmosis
Start date: 2012-07-01
End date: 2012-07-11
Sulfadiazine
Dosage: 2000 mg;qd;
Indication: Toxoplasmosis
Start date: 2012-06-30
End date: 2012-07-11
Other drugs received by patient: Synthroid; Simvastatin
Possible Daraprim side effects in 38 year old female
Reported by a physician from Germany on 2012-07-17
Patient: 38 year old female
Reactions: Phenylketonuria, Amino Acid Level Increased, Maternal Exposure During Pregnancy, Condition Aggravated, Transaminases Increased
Drug(s) suspected as cause:
Daraprim
Other drugs received by patient: Leucovorin Calcium; Vitamin B12 + Folic Acid; Sulphadiazine; Spiramycin
Possible Daraprim side effects in 54 year old male
Reported by a physician from United States on 2012-03-20
Patient: 54 year old male
Reactions: Exophthalmos, Respiratory Disorder, Pancytopenia, Toxicity To Various Agents, Haemodynamic Instability, Mental Impairment, Zygomycosis, Bone Marrow Failure, Blindness Unilateral, Sinusitis Fungal, Eyelid Ptosis, Ophthalmoplegia, Maculopathy
Adverse event resulted in: death, hospitalization, disablity
Drug(s) suspected as cause:
Clindamycin
Indication: Cerebral Toxoplasmosis
Dapsone
Indication: Antifungal Prophylaxis
Daraprim
Indication: Cerebral Toxoplasmosis
Dexamethasone
Indication: Brain Oedema
Other drugs received by patient: Insulin
Possible Daraprim side effects in 47 year old female
Reported by a individual with unspecified qualification from United Kingdom on 2011-10-03
Patient: 47 year old female
Reactions: Cardiac Murmur, Mouth Ulceration, Pancytopenia, Blood Folate Increased, Headache, Accidental Overdose, Tremor, Anaemia Vitamin B12 Deficiency, Speech Disorder, Malaise, Fatigue, Palpitations, Abdominal Distension, Serum Ferritin Decreased, Asthenia
Drug(s) suspected as cause:
Daraprim
Other drugs received by patient: Fybogel Sachets
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